ATE226815T1 - Herstellung von arzneimitteln - Google Patents

Herstellung von arzneimitteln

Info

Publication number
ATE226815T1
ATE226815T1 AT98930903T AT98930903T ATE226815T1 AT E226815 T1 ATE226815 T1 AT E226815T1 AT 98930903 T AT98930903 T AT 98930903T AT 98930903 T AT98930903 T AT 98930903T AT E226815 T1 ATE226815 T1 AT E226815T1
Authority
AT
Austria
Prior art keywords
ethanol
manufacturing
composition
medicinal products
dissolved
Prior art date
Application number
AT98930903T
Other languages
English (en)
Inventor
Steven Leigh
Mathew Louis Steven Leigh
Original Assignee
Phares Pharm Res Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phares Pharm Res Nv filed Critical Phares Pharm Res Nv
Application granted granted Critical
Publication of ATE226815T1 publication Critical patent/ATE226815T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98930903T 1997-06-20 1998-06-19 Herstellung von arzneimitteln ATE226815T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9713140A GB2326337A (en) 1997-06-20 1997-06-20 Homogeneous lipid compositions for drug delivery
PCT/GB1998/001803 WO1998058629A2 (en) 1997-06-20 1998-06-19 Preparation of pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE226815T1 true ATE226815T1 (de) 2002-11-15

Family

ID=10814725

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98930903T ATE226815T1 (de) 1997-06-20 1998-06-19 Herstellung von arzneimitteln

Country Status (12)

Country Link
US (1) US6599527B1 (de)
EP (1) EP1011634B1 (de)
JP (1) JP2002507966A (de)
AT (1) ATE226815T1 (de)
AU (1) AU731397B2 (de)
CA (1) CA2294337C (de)
DE (1) DE69809074T2 (de)
DK (1) DK1011634T3 (de)
ES (1) ES2185179T3 (de)
GB (1) GB2326337A (de)
PT (1) PT1011634E (de)
WO (1) WO1998058629A2 (de)

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GB2326337A (en) 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
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WO1999044642A1 (en) * 1998-03-05 1999-09-10 Phares Pharmaceutical Research Nv Pharmaceutical compositions and their use
WO2000033817A1 (en) * 1998-12-08 2000-06-15 Phares Pharmaceutical Research N.V. Phospholipid compositions
ATE404172T1 (de) 1998-12-30 2008-08-15 Dexcel Ltd Dispergierbares konzentrat zur verabreichung von cyclosporin
GB9908309D0 (en) * 1999-04-12 1999-06-02 Phares Pharm Res Nv Lipid aggregate forming compositions and their use
US20030064948A1 (en) * 2001-02-08 2003-04-03 Alfred Fahr Invasomes for therapy of disorders, their preparation and use
WO2003105611A2 (en) 2002-06-12 2003-12-24 The Coca-Cola Company Beverages containing plant sterols
US7306819B2 (en) 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
DE10233632A1 (de) * 2002-07-24 2004-02-05 Wilex Ag Formulierungen von Phenylalanin-Derivaten
US20050196370A1 (en) * 2003-03-18 2005-09-08 Zhi-Jian Yu Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye
US20040185068A1 (en) * 2003-03-18 2004-09-23 Zhi-Jian Yu Self-emulsifying compositions, methods of use and preparation
GB0317869D0 (en) * 2003-07-30 2003-09-03 Disperse Ltd Improved drug delivery system
US7659310B2 (en) * 2004-04-27 2010-02-09 Formatech, Inc. Methods of enhancing solubility of agents
WO2005105041A2 (en) * 2004-04-27 2005-11-10 Formatech, Inc. Methods of enhancing solubility in water of hydrophobic compounds by micellar dispersions
US20050255154A1 (en) 2004-05-11 2005-11-17 Lena Pereswetoff-Morath Method and composition for treating rhinitis
WO2005110360A2 (en) * 2004-05-18 2005-11-24 Phares Pharmaceutical Research N.V. Compositions for injection
US20060014677A1 (en) * 2004-07-19 2006-01-19 Isotechnika International Inc. Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
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EP2200613B1 (de) 2007-09-21 2018-09-05 The Johns Hopkins University Phenazin-derivate und ihre verwendungen
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
CA2781527C (en) * 2009-09-23 2017-10-24 Indu Javeri Methods for the preparation of liposomes
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
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US20120028335A1 (en) 2010-07-28 2012-02-02 Life Technologies Corporation Anti-viral azide-containing compounds
HRP20191711T1 (hr) 2011-03-14 2019-12-13 Drug Delivery Solutions Ltd Oftalmološki pripravak
US9644038B2 (en) 2011-12-21 2017-05-09 The Regents Of The University Of California Apolipoprotein nanodiscs with telodendrimer
AU2013212068B2 (en) 2012-01-26 2018-02-15 Life Technologies Corporation Methods for increasing the infectivity of viruses
DE102012008822A1 (de) 2012-05-07 2013-11-07 GM Global Technology Operations LLC (n.d. Ges. d. Staates Delaware) Verstellvorrichtung, Kraftfahrzeugsitz, Kraftfahrzeug und Verfahren hierzu
EP2846773A4 (de) 2012-05-10 2015-12-30 Painreform Ltd Depotformulierungen eines lokalanästhetikums und verfahren zur herstellung davon
WO2017035326A1 (en) 2015-08-25 2017-03-02 Lawrence Livermore National Security, Llc Stable nanolipoprotein particles and related compositions methods and systems
WO2017044899A1 (en) 2015-09-11 2017-03-16 Lawrence Livermore National Security, Llc Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation
WO2017155837A1 (en) * 2016-03-07 2017-09-14 Lawrence Livermore National Security, Llc Nanolipoprotein particles and related compositions methods and systems for improved drug loading
US12083223B2 (en) 2017-05-02 2024-09-10 Lawrence Livermore National Security, Llc Nanolipoprotein particles and related compositions methods and systems for loading RNA
US11207422B2 (en) 2017-05-02 2021-12-28 Lawrence Livermore National Security, Llc MOMP telonanoparticles, and related compositions, methods and systems
EP3542788A1 (de) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topische zusammensetzung enthaltend calcipotriol und betamethason dipropionat
CA3107841C (en) * 2019-10-18 2023-05-09 Deciem Beauty Group Inc. Skin care formulation with lipophilic peptides

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Also Published As

Publication number Publication date
GB2326337A (en) 1998-12-23
DE69809074D1 (de) 2002-12-05
CA2294337A1 (en) 1998-12-30
PT1011634E (pt) 2003-03-31
CA2294337C (en) 2007-05-15
EP1011634A1 (de) 2000-06-28
JP2002507966A (ja) 2002-03-12
AU731397B2 (en) 2001-03-29
WO1998058629A2 (en) 1998-12-30
DK1011634T3 (da) 2003-03-03
AU8118498A (en) 1999-01-04
EP1011634B1 (de) 2002-10-30
DE69809074T2 (de) 2003-06-26
GB9713140D0 (en) 1997-08-27
US6599527B1 (en) 2003-07-29
WO1998058629A3 (en) 1999-03-18
ES2185179T3 (es) 2003-04-16

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