ATE2272T1 - 9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2b)thiophen-4,9-imine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. - Google Patents

9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2b)thiophen-4,9-imine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.

Info

Publication number: ATE2272T1
Authority: AT; Austria
Prior art keywords: cyclohepta; thiophen; benzo; dihydro; imine
Prior art date: 1978-11-15

Application number

AT79104306T

Other languages

English (en)

Inventor

Paul S. Anderson

Ben E. Evans

Original Assignee

Merck & Co. Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-11-15

Filing date

1979-11-05

Publication date

1983-02-15

1979-11-05 Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.

1983-02-15 Application granted granted Critical

1983-02-15 Publication of ATE2272T1 publication Critical patent/ATE2272T1/de

Links

238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
208000018737 Parkinson disease Diseases 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
208000018300 basal ganglia disease Diseases 0.000 abstract 1
229940035363 muscle relaxants Drugs 0.000 abstract 1
239000003158 myorelaxant agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

AT79104306T 1978-11-15 1979-11-05 9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2b)thiophen-4,9-imine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. ATE2272T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US05/960,811 US4252810A (en)	1978-11-15	1978-11-15	9,10-Dihydro-4H-benzo[4,5]cyclohepta [1,2-b]thiophen-4,9-imines
EP79104306A EP0011206B1 (de)	1978-11-15	1979-11-05	9,10-Dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thiophen-4,9-imine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate

Publications (1)

Publication Number	Publication Date
ATE2272T1 true ATE2272T1 (de)	1983-02-15

Family

ID=25503670

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT79104306T ATE2272T1 (de)	1978-11-15	1979-11-05	9,10-dihydro-4h-benzo(4,5)cyclohepta(1,2b)thiophen-4,9-imine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.

Country Status (6)

Country	Link
US (1)	US4252810A (de)
EP (1)	EP0011206B1 (de)
JP (1)	JPS5572193A (de)
AT (1)	ATE2272T1 (de)
DE (1)	DE2964557D1 (de)
DK (1)	DK480979A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196415A (en) *	1989-05-09	1993-03-23	The United States Of America As Represented By The Department Of Health And Human Services	5-aminocarbonyl-5H-dibenzo[a.d]cyclohepten-5,10-imines for treatment of epilepsy and cocaine addiction
US5260309A (en) *	1989-06-01	1993-11-09	Pfizer Inc.	4,5,6,11-tetrahydrobenzo [6,7] cycloocta [1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo [6,7] cycloocta [1,2-b] thiophen-6,11-imines
WO1990015060A1 (en) *	1989-06-01	1990-12-13	Pfizer Inc.	4,5,6,11-TETRAHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES AND 6,11-DIHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES
US5064831A (en) *	1990-09-14	1991-11-12	Bristol-Myers Squibb Co.	Naphthothiophenimines for treating neuronal disorders caused by ischemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE794904A (fr) *	1972-02-04	1973-08-02	Roussel Uclaf	Nouveaux derives du dibenzocycloheptene et leur preparation
US4064139A (en) *	1975-04-07	1977-12-20	Merck & Co., Inc.	Substituted 9,10-dihydroanthracen-9,10-imines
US4123546A (en) *	1977-07-01	1978-10-31	E. I. Du Pont De Nemours And Company	Antidepressant compounds
IL56112A0 (en) *	1977-12-15	1979-03-12	Merck & Co Inc	Imino-bridged benzocycloheptapyridines

1978
- 1978-11-15 US US05/960,811 patent/US4252810A/en not_active Expired - Lifetime
1979
- 1979-11-05 DE DE7979104306T patent/DE2964557D1/de not_active Expired
- 1979-11-05 EP EP79104306A patent/EP0011206B1/de not_active Expired
- 1979-11-05 AT AT79104306T patent/ATE2272T1/de not_active IP Right Cessation
- 1979-11-14 DK DK480979A patent/DK480979A/da not_active Application Discontinuation
- 1979-11-15 JP JP14718079A patent/JPS5572193A/ja active Pending

Also Published As

Publication number	Publication date
DK480979A (da)	1980-05-16
US4252810A (en)	1981-02-24
DE2964557D1 (en)	1983-02-24
JPS5572193A (en)	1980-05-30
EP0011206B1 (de)	1983-01-19
EP0011206A1 (de)	1980-05-28

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Legal Events

Date	Code	Title	Description
1983-08-15	UEP	Publication of translation of european patent specification
1985-08-15	REN	Ceased due to non-payment of the annual fee