ATE227736T1 - Lösliche proteine - Google Patents

Lösliche proteine

Info

Publication number
ATE227736T1
ATE227736T1 AT97918634T AT97918634T ATE227736T1 AT E227736 T1 ATE227736 T1 AT E227736T1 AT 97918634 T AT97918634 T AT 97918634T AT 97918634 T AT97918634 T AT 97918634T AT E227736 T1 ATE227736 T1 AT E227736T1
Authority
AT
Austria
Prior art keywords
protein
native protein
proteins
soluble
native
Prior art date
Application number
AT97918634T
Other languages
English (en)
Inventor
Stanley B Prusiner
Fred E Cohen
Tamaki Muramoto
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE227736T1 publication Critical patent/ATE227736T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Bipolar Transistors (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
AT97918634T 1996-11-05 1997-04-15 Lösliche proteine ATE227736T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/740,947 US5834593A (en) 1996-11-05 1996-11-05 Soluble form of PrPSC which is insoluble in native form
PCT/US1997/006227 WO1998020022A1 (en) 1996-11-05 1997-04-15 Soluble proteins

Publications (1)

Publication Number Publication Date
ATE227736T1 true ATE227736T1 (de) 2002-11-15

Family

ID=24978724

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97918634T ATE227736T1 (de) 1996-11-05 1997-04-15 Lösliche proteine

Country Status (13)

Country Link
US (1) US5834593A (de)
EP (1) EP1012162B1 (de)
JP (1) JP2001506979A (de)
AT (1) ATE227736T1 (de)
AU (1) AU720533B2 (de)
BR (1) BR9712874A (de)
CA (1) CA2268354A1 (de)
DE (1) DE69717167T2 (de)
DK (1) DK1012162T3 (de)
ES (1) ES2186886T3 (de)
NZ (1) NZ335103A (de)
PT (1) PT1012162E (de)
WO (1) WO1998020022A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2758337B1 (fr) * 1997-01-14 1999-03-05 Commissariat Energie Atomique Methode de criblage de substances a action therapeutique dans le traitement des esst comprenant une etape d'isolement de la prpres, a partir de la rate, procede d'isolement de le prpres et ses applications
GB2348203B (en) 1998-11-04 2002-06-19 Imp College Innovations Ltd Solube beta-forms of prion proteins, methods of preparation and use
US6166187A (en) * 1999-03-05 2000-12-26 The Regents Of The University Of California Method of concentrating prion proteins in blood samples
DE19918141A1 (de) * 1999-04-21 2000-10-26 Boehringer Ingelheim Vetmed Verfahren zur Diagnose von übertragbaren Spongiformen Enzephalopathien
US6437102B1 (en) 1999-11-24 2002-08-20 Bayer Corporation Method of separating prions from biological materials
WO2002079416A2 (en) * 2001-03-30 2002-10-10 Texas A & M University System Transgenic animals resistant to transmissible spongiform encephalopathies
GB0419628D0 (en) * 2004-09-03 2004-10-06 European Molecular Biology Lab Embl Method for determining protein solubility

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
US5266684A (en) * 1988-05-02 1993-11-30 The Reagents Of The University Of California Peptide mixtures
WO1991002002A1 (en) * 1989-07-21 1991-02-21 Washington University Recombinantly produced human membrane cofactor protein (mcp)
US5182366A (en) * 1990-05-15 1993-01-26 Huebner Verena D Controlled synthesis of peptide mixtures using mixed resins
EP0613495B1 (de) * 1991-11-14 2005-02-02 WEISSMANN, Charles Transgene nicht-menschliche tiere ohne prionprotein
WO1993023432A1 (en) * 1992-05-15 1993-11-25 New York University Soluble prion polypeptides, and methods for detecting and purifying thereof
US5605691A (en) * 1992-09-17 1997-02-25 Ophidian Pharmaceuticals, Inc. Immunologically active proteins from inclusion bodies
US5565186A (en) * 1994-05-13 1996-10-15 The Regents Of The University Of California Method of detecting prions in a sample and transgenic animal used for same

Also Published As

Publication number Publication date
WO1998020022A1 (en) 1998-05-14
EP1012162A1 (de) 2000-06-28
US5834593A (en) 1998-11-10
JP2001506979A (ja) 2001-05-29
CA2268354A1 (en) 1998-05-14
EP1012162A4 (de) 2000-06-28
PT1012162E (pt) 2003-04-30
BR9712874A (pt) 2000-02-01
DE69717167T2 (de) 2003-07-24
AU2669497A (en) 1998-05-29
AU720533B2 (en) 2000-06-01
EP1012162B1 (de) 2002-11-13
ES2186886T3 (es) 2003-05-16
DK1012162T3 (da) 2003-03-10
NZ335103A (en) 2000-10-27
DE69717167D1 (de) 2002-12-19

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