ATE228127T1 - Neue verwendung und neue derivate von imidazol, ihrer herstellung, zwischenprodukte, und verwendung als arzneimittel - Google Patents

Neue verwendung und neue derivate von imidazol, ihrer herstellung, zwischenprodukte, und verwendung als arzneimittel

Info

Publication number
ATE228127T1
ATE228127T1 AT95927004T AT95927004T ATE228127T1 AT E228127 T1 ATE228127 T1 AT E228127T1 AT 95927004 T AT95927004 T AT 95927004T AT 95927004 T AT95927004 T AT 95927004T AT E228127 T1 ATE228127 T1 AT E228127T1
Authority
AT
Austria
Prior art keywords
new
pct
products
alkenyl
alkyl
Prior art date
Application number
AT95927004T
Other languages
English (en)
Inventor
Bertrand Heckmann
Jean-Paul Vevert
Jidong Zhang
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE228127T1 publication Critical patent/ATE228127T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Retarders (AREA)
AT95927004T 1994-08-02 1995-08-01 Neue verwendung und neue derivate von imidazol, ihrer herstellung, zwischenprodukte, und verwendung als arzneimittel ATE228127T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9409566A FR2723370B1 (fr) 1994-08-02 1994-08-02 Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
PCT/FR1995/001034 WO1996004276A1 (fr) 1994-08-02 1995-08-01 Nouvelle utilisation et nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
ATE228127T1 true ATE228127T1 (de) 2002-12-15

Family

ID=9465986

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95927004T ATE228127T1 (de) 1994-08-02 1995-08-01 Neue verwendung und neue derivate von imidazol, ihrer herstellung, zwischenprodukte, und verwendung als arzneimittel

Country Status (20)

Country Link
US (1) US5811444A (de)
EP (1) EP0776325B1 (de)
JP (1) JP4044134B2 (de)
CN (1) CN1082961C (de)
AT (1) ATE228127T1 (de)
AU (1) AU707927B2 (de)
BR (1) BR9508481A (de)
CA (1) CA2196218A1 (de)
DE (1) DE69528902T2 (de)
DK (1) DK0776325T3 (de)
ES (1) ES2182909T3 (de)
FI (1) FI970424L (de)
FR (1) FR2723370B1 (de)
HU (1) HU221464B (de)
IL (1) IL114753A0 (de)
MX (1) MX9700821A (de)
PT (1) PT776325E (de)
RU (1) RU2187507C2 (de)
WO (1) WO1996004276A1 (de)
ZA (1) ZA956453B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2740773B1 (fr) * 1995-11-08 1997-12-19 Roussel Uclaf Nouveaux derives de l'imidazole, procede de preparation, intermediaires obtenus, application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
FR2740774B1 (fr) * 1995-11-08 1997-12-19 Roussel Uclaf Nouveaux derives d'imidazole n-benzyldioxole, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
FR2831822A1 (fr) * 2001-11-07 2003-05-09 Inst Nat Sante Rech Med Utilisation therapeutique de derives 4-mercapto- ou 4-seleno-imidazoles
JP6138834B2 (ja) * 2012-02-16 2017-05-31 ダウ アグロサイエンシィズ エルエルシー スルフィルイミン化合物の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003732B1 (de) * 1978-02-01 1983-10-19 The Wellcome Foundation Limited Imidazolderivate und deren Salze, deren Herstellung sowie deren pharmazeutische Zusammensetzungen
WO1994002474A1 (en) * 1992-07-17 1994-02-03 Smithkline Beecham Corporation Endothelin receptor antagonists
US5559105A (en) * 1992-07-17 1996-09-24 Smithkline Beecham Corporation Endothelin receptor antagonists

Also Published As

Publication number Publication date
JP4044134B2 (ja) 2008-02-06
IL114753A0 (en) 1995-11-27
FR2723370A1 (fr) 1996-02-09
DK0776325T3 (da) 2003-03-17
PT776325E (pt) 2003-03-31
EP0776325B1 (de) 2002-11-20
WO1996004276A1 (fr) 1996-02-15
HU221464B (en) 2002-10-28
CN1082961C (zh) 2002-04-17
FI970424A7 (fi) 1997-04-01
MX9700821A (es) 1997-05-31
DE69528902T2 (de) 2003-04-10
BR9508481A (pt) 1997-09-30
FI970424L (fi) 1997-04-01
AU3117995A (en) 1996-03-04
JPH10504544A (ja) 1998-05-06
ES2182909T3 (es) 2003-03-16
AU707927B2 (en) 1999-07-22
US5811444A (en) 1998-09-22
EP0776325A1 (de) 1997-06-04
CA2196218A1 (fr) 1996-02-15
RU2187507C2 (ru) 2002-08-20
FI970424A0 (fi) 1997-01-31
FR2723370B1 (fr) 1996-09-13
HUT77767A (hu) 1998-08-28
CN1158613A (zh) 1997-09-03
ZA956453B (en) 1996-08-05
DE69528902D1 (de) 2003-01-02

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