ATE228165T1 - Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien - Google Patents

Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien

Info

Publication number
ATE228165T1
ATE228165T1 AT96117455T AT96117455T ATE228165T1 AT E228165 T1 ATE228165 T1 AT E228165T1 AT 96117455 T AT96117455 T AT 96117455T AT 96117455 T AT96117455 T AT 96117455T AT E228165 T1 ATE228165 T1 AT E228165T1
Authority
AT
Austria
Prior art keywords
amino acids
carbamoylase
hydantoinase
operon
production
Prior art date
Application number
AT96117455T
Other languages
English (en)
Inventor
Renata Grifantini
Giuliano Galli
Guido Grandi
Giovanna Carpani
Original Assignee
Enitecnologie Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enitecnologie Spa filed Critical Enitecnologie Spa
Application granted granted Critical
Publication of ATE228165T1 publication Critical patent/ATE228165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT96117455T 1995-11-23 1996-10-31 Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien ATE228165T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI002432A IT1276163B1 (it) 1995-11-23 1995-11-23 Procedimento migliorato per la preparazione di d-alfa-amminoacidi

Publications (1)

Publication Number Publication Date
ATE228165T1 true ATE228165T1 (de) 2002-12-15

Family

ID=11372580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96117455T ATE228165T1 (de) 1995-11-23 1996-10-31 Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien

Country Status (6)

Country Link
US (1) US5834258A (de)
EP (1) EP0775748B1 (de)
JP (1) JP3768309B2 (de)
AT (1) ATE228165T1 (de)
DE (1) DE69624898D1 (de)
IT (1) IT1276163B1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524837B1 (en) 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids
NL1019416C2 (nl) * 2001-11-23 2003-06-02 Dsm Nv Werkwijze voor het bereiden van een enantiomeer verrijkt a-aminozuur.
WO2003085108A1 (fr) * 2002-04-10 2003-10-16 Ajinomoto Co., Inc. Adn recombinant presentant un gene d'hydantoinase et un gene de carbamylase et procede de production d'acide amine
JP6363326B2 (ja) * 2013-03-11 2018-07-25 株式会社コーセー 酵母・細菌共通培養方法およびこれに用いる酵母・細菌共通培養培地
CN111621452A (zh) * 2019-02-28 2020-09-04 中国科学院微生物研究所 一株生产d-对羟基苯甘氨酸的枯草芽孢杆菌
CN112080532A (zh) * 2020-09-27 2020-12-15 铜陵利夫生物科技有限公司 一种双酶法生产d-对羟基苯甘氨酸的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1046399B (it) 1975-05-12 1980-06-30 Snam Progetti Procedimento per la preparazione di d carbamil amminoacidi e dei corrispondenti d amminoacidi
IT1039757B (it) 1975-07-10 1979-12-10 Snam Progetti Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione
IT1109506B (it) 1978-05-23 1985-12-16 Snam Progetti Processo enzimatico-microbiologico per la produzione di amminoacidi otticamente attivi a partire da idantoine e/o carbamil-derivati racemi
FR2456728A1 (fr) 1979-05-15 1980-12-12 Aec Chim Organ Biolog Procede de preparation de d-a-aminoacides
JPS61212292A (ja) 1985-03-19 1986-09-20 Mitsui Toatsu Chem Inc Ｄ−α−アミノ酸の製造方法
DE3535987A1 (de) 1985-10-09 1987-04-23 Basf Ag Verfahren zur herstellung von meophilen mikroorganismen, die eine bei hoeherer temperatur aktive d-hydantoinase enthalten
FR2620731B1 (fr) 1987-09-21 1990-03-23 Hoechst France Nouveau systeme enzymatique, son procede de preparation et son application notamment dans la preparation de la d-parahydroxyphenylglycine
DE69129899T2 (de) 1990-12-07 1999-01-14 Kanegafuchi Kagaku Kogyo K.K., Osaka Verfahren zur Herstellung von D-Alpha-Aminosäuren
WO1994000577A1 (en) * 1992-06-30 1994-01-06 Smithkline Beecham P.L.C. D-n-carbamoyl-amino acid amidohydrolase and hydantoinase
KR100292558B1 (ko) * 1992-09-07 2001-06-01 오꾸야마 잇슨보오시 호퍼 부착 기기의 호퍼처리법 및 호퍼
IT1274167B (it) * 1994-04-15 1997-07-15 Eniricerche Spa Procedimento per la produzione di d- -amminoacidi
CN1088473C (zh) * 1994-06-24 2002-07-31 钟渊化学工业株式会社 用复合固相酶制品生产d－氨基酸的方法

Also Published As

Publication number Publication date
IT1276163B1 (it) 1997-10-27
EP0775748A2 (de) 1997-05-28
ITMI952432A0 (de) 1995-11-23
DE69624898D1 (de) 2003-01-02
US5834258A (en) 1998-11-10
JP3768309B2 (ja) 2006-04-19
EP0775748A3 (de) 1999-04-07
EP0775748B1 (de) 2002-11-20
ITMI952432A1 (it) 1997-05-23
JPH09187286A (ja) 1997-07-22

Similar Documents

Publication Publication Date Title
ATE210728T1 (de) Herstellungsverfahren einer substanz
DK88586D0 (da) Fremgangsmaade til fremstilling af l-carnitin ad mikrobiologisk vej
PT824873E (pt) Producao de um condimento
ATE196776T1 (de) Neue mikroorganismen, deren verwendung und verfahren zur herstellung von l-alpha-aminosäuren
EP0264457A4 (de) Herstellung optisch aktiver cyclopropancarbonsäuren.
ATE106451T1 (de) Fermentationsverfahren zur herstellung von 2-keto-l-gulonsäure.
DE69022522D1 (de) Herstellung von aminosäuren durch methylotrophe bazillen.
ATE228165T1 (de) Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien
EP0859050A4 (de) Alkaline protease, verfahren zu ihrer herstellung, anwendung derselben und diese herstellende mikroorganismen
ATE155814T1 (de) Verfahren zur herstellung von d-alpha-aminosäuren
DE3584218D1 (de) Herstellung von derivaten von a-21978c.
US5714355A (en) Microorganism, use thereof and process for the production of L-α-amino acids
SE8403933D0 (sv) Production of l-amino acids from alpha-keto acids
PL349759A1 (en) Method of obtaining non-poroteinous l-amino acids by fermentation process
DK0549710T3 (da) Fremgangsmåde til fremstilling af enantiomere 2-alkansyrer
DE69305773D1 (de) Herstellung von Diacetyl
AU4613100A (en) Process for producing optically active azetidine-2-carboxylic acids
BR0005307A (pt) Processo para a produção fermentativa de l-lisina usando bactérias coryneform
ATE203232T1 (de) Verfahren zur herstellung von n-acetyl-d,l-alpha- aminocarbonsäuren
ES2124714T3 (es) Procedimiento de ingenieria genetica para la preparacion de s-(+)-2,2-dimetilciclopropanocarboxamida mediante microorganismos.
DE69228761D1 (de) Verfahren zur herstellung von neuraminidase
MY102317A (en) Novel microorganisms and a method for production of glutamic acid using the same.
ATE117289T1 (de) Herstellung von pyridazinon.
DE68918776D1 (de) Verfahren zur Herstellung von Biokatalysatoren mit vorher fehlender stereoselektiver Enzymaktivität.
MY100385A (en) Process for producing l-amino acids or 5''-inosinic acid by fermentation.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties