ATE228165T1 - Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien - Google Patents
Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterienInfo
- Publication number
- ATE228165T1 ATE228165T1 AT96117455T AT96117455T ATE228165T1 AT E228165 T1 ATE228165 T1 AT E228165T1 AT 96117455 T AT96117455 T AT 96117455T AT 96117455 T AT96117455 T AT 96117455T AT E228165 T1 ATE228165 T1 AT E228165T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acids
- carbamoylase
- hydantoinase
- operon
- production
- Prior art date
Links
- 150000007650 D alpha amino acids Chemical class 0.000 title abstract 3
- 241000894006 Bacteria Species 0.000 title 1
- 244000005700 microbiome Species 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 230000002255 enzymatic effect Effects 0.000 abstract 2
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 150000001469 hydantoins Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI002432A IT1276163B1 (it) | 1995-11-23 | 1995-11-23 | Procedimento migliorato per la preparazione di d-alfa-amminoacidi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE228165T1 true ATE228165T1 (de) | 2002-12-15 |
Family
ID=11372580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96117455T ATE228165T1 (de) | 1995-11-23 | 1996-10-31 | Herstellung von d-alpha-aminosäuren, unter verwendung von mit dem carbamoylase-hydantoinase- operon-transformierten bakterien |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5834258A (de) |
| EP (1) | EP0775748B1 (de) |
| JP (1) | JP3768309B2 (de) |
| AT (1) | ATE228165T1 (de) |
| DE (1) | DE69624898D1 (de) |
| IT (1) | IT1276163B1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6524837B1 (en) | 1999-03-29 | 2003-02-25 | California Institute Of Technology | Hydantoinase variants with improved properties and their use for the production of amino acids |
| NL1019416C2 (nl) * | 2001-11-23 | 2003-06-02 | Dsm Nv | Werkwijze voor het bereiden van een enantiomeer verrijkt a-aminozuur. |
| WO2003085108A1 (fr) * | 2002-04-10 | 2003-10-16 | Ajinomoto Co., Inc. | Adn recombinant presentant un gene d'hydantoinase et un gene de carbamylase et procede de production d'acide amine |
| JP6363326B2 (ja) * | 2013-03-11 | 2018-07-25 | 株式会社コーセー | 酵母・細菌共通培養方法およびこれに用いる酵母・細菌共通培養培地 |
| CN111621452A (zh) * | 2019-02-28 | 2020-09-04 | 中国科学院微生物研究所 | 一株生产d-对羟基苯甘氨酸的枯草芽孢杆菌 |
| CN112080532A (zh) * | 2020-09-27 | 2020-12-15 | 铜陵利夫生物科技有限公司 | 一种双酶法生产d-对羟基苯甘氨酸的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1046399B (it) | 1975-05-12 | 1980-06-30 | Snam Progetti | Procedimento per la preparazione di d carbamil amminoacidi e dei corrispondenti d amminoacidi |
| IT1039757B (it) | 1975-07-10 | 1979-12-10 | Snam Progetti | Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione |
| IT1109506B (it) | 1978-05-23 | 1985-12-16 | Snam Progetti | Processo enzimatico-microbiologico per la produzione di amminoacidi otticamente attivi a partire da idantoine e/o carbamil-derivati racemi |
| FR2456728A1 (fr) | 1979-05-15 | 1980-12-12 | Aec Chim Organ Biolog | Procede de preparation de d-a-aminoacides |
| JPS61212292A (ja) | 1985-03-19 | 1986-09-20 | Mitsui Toatsu Chem Inc | Ｄ−α−アミノ酸の製造方法 |
| DE3535987A1 (de) | 1985-10-09 | 1987-04-23 | Basf Ag | Verfahren zur herstellung von meophilen mikroorganismen, die eine bei hoeherer temperatur aktive d-hydantoinase enthalten |
| FR2620731B1 (fr) | 1987-09-21 | 1990-03-23 | Hoechst France | Nouveau systeme enzymatique, son procede de preparation et son application notamment dans la preparation de la d-parahydroxyphenylglycine |
| US5565344A (en) | 1990-12-07 | 1996-10-15 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Process for production of D-α-amino acids |
| WO1994000577A1 (en) * | 1992-06-30 | 1994-01-06 | Smithkline Beecham P.L.C. | D-n-carbamoyl-amino acid amidohydrolase and hydantoinase |
| KR100292558B1 (ko) * | 1992-09-07 | 2001-06-01 | 오꾸야마 잇슨보오시 | 호퍼 부착 기기의 호퍼처리법 및 호퍼 |
| IT1274167B (it) * | 1994-04-15 | 1997-07-15 | Eniricerche Spa | Procedimento per la produzione di d- -amminoacidi |
| JP3996183B2 (ja) * | 1994-06-24 | 2007-10-24 | 株式会社カネカ | 複合固定化酵素調製物を用いたｄ−アミノ酸の製造方法 |
-
1995
- 1995-11-23 IT IT95MI002432A patent/IT1276163B1/it active IP Right Grant
-
1996
- 1996-10-31 DE DE69624898T patent/DE69624898D1/de not_active Expired - Lifetime
- 1996-10-31 AT AT96117455T patent/ATE228165T1/de not_active IP Right Cessation
- 1996-10-31 EP EP96117455A patent/EP0775748B1/de not_active Expired - Lifetime
- 1996-11-06 US US08/744,829 patent/US5834258A/en not_active Expired - Fee Related
- 1996-11-25 JP JP31389396A patent/JP3768309B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT1276163B1 (it) | 1997-10-27 |
| DE69624898D1 (de) | 2003-01-02 |
| US5834258A (en) | 1998-11-10 |
| JP3768309B2 (ja) | 2006-04-19 |
| EP0775748A3 (de) | 1999-04-07 |
| EP0775748B1 (de) | 2002-11-20 |
| EP0775748A2 (de) | 1997-05-28 |
| ITMI952432A1 (it) | 1997-05-23 |
| JPH09187286A (ja) | 1997-07-22 |
| ITMI952432A0 (de) | 1995-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |