ATE228372T1 - Hcg und derivate als matrixmetalloprotease- inhibitoren - Google Patents

Hcg und derivate als matrixmetalloprotease- inhibitoren

Info

Publication number
ATE228372T1
ATE228372T1 AT97934545T AT97934545T ATE228372T1 AT E228372 T1 ATE228372 T1 AT E228372T1 AT 97934545 T AT97934545 T AT 97934545T AT 97934545 T AT97934545 T AT 97934545T AT E228372 T1 ATE228372 T1 AT E228372T1
Authority
AT
Austria
Prior art keywords
hcg
derivatives
matrix metalloprotease
metalloprotease inhibitors
inhibitors
Prior art date
Application number
AT97934545T
Other languages
English (en)
Inventor
Adriana Albini
Giorgia Orengo
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of ATE228372T1 publication Critical patent/ATE228372T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT97934545T 1996-08-07 1997-07-25 Hcg und derivate als matrixmetalloprotease- inhibitoren ATE228372T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96RM000566A IT1284876B1 (it) 1996-08-07 1996-08-07 Hcg come inibitore della collagenasi
PCT/EP1997/004053 WO1998005353A1 (en) 1996-08-07 1997-07-25 hCG AND DERIVATIVES AS MATRIX METALLOPROTEASES INHIBITORS

Publications (1)

Publication Number Publication Date
ATE228372T1 true ATE228372T1 (de) 2002-12-15

Family

ID=11404385

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97934545T ATE228372T1 (de) 1996-08-07 1997-07-25 Hcg und derivate als matrixmetalloprotease- inhibitoren

Country Status (14)

Country Link
US (1) US6444639B2 (de)
EP (1) EP0920330B1 (de)
JP (1) JP3996952B2 (de)
AR (1) AR009013A1 (de)
AT (1) ATE228372T1 (de)
AU (1) AU732972B2 (de)
CA (1) CA2262582C (de)
DE (1) DE69717463T2 (de)
DK (1) DK0920330T3 (de)
ES (1) ES2183205T3 (de)
IL (1) IL128399A (de)
IT (1) IT1284876B1 (de)
PT (1) PT920330E (de)
WO (1) WO1998005353A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE457716T1 (de) 2002-12-30 2010-03-15 Angiotech Int Ag Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
EP1740202B1 (de) 2004-02-13 2012-05-09 Stem Cell Therapeutics Corp. Verwendung des luteinisierenden hormons (lh) und von choriongonadotrophin (hcg) für die proliferation von neuralen stammzellen und neurogenese
JP2008515818A (ja) 2004-10-07 2008-05-15 ステム セル セラピューティクス コーポレイション 妊娠に関連する化合物の投与による多能性幹細胞の増殖の刺激
JP2009530235A (ja) 2006-03-17 2009-08-27 ステム セル セラピューティクス コーポレイション 神経幹細胞増殖剤および神経幹細胞分化剤の連続投与レジメン
CN106535923A (zh) * 2014-07-15 2017-03-22 泽特奇克研究机构有限责任公司 用于预防和治疗眼部疾病的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1250075B (it) * 1991-12-18 1995-03-30 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti gonadotropine.
US5677275A (en) * 1994-08-05 1997-10-14 The United States Of America As Represented By The Department Of Health And Human Services Treatment of cancer with human chorionic gonadotropin
US6251402B1 (en) 1995-10-16 2001-06-26 Applied Research Systems Ars Holding N.V. Use of human chorionic gonadotropin in the treatment of Kaposi's sarcoma
US5968513A (en) * 1996-06-24 1999-10-19 University Of Maryland Biotechnology Institute Method of promoting hematopoiesis using derivatives of human chorionic gonadotropin

Also Published As

Publication number Publication date
CA2262582C (en) 2009-02-24
JP2000516582A (ja) 2000-12-12
IL128399A0 (en) 2000-01-31
US6444639B2 (en) 2002-09-03
AU3771197A (en) 1998-02-25
AU732972B2 (en) 2001-05-03
ES2183205T3 (es) 2003-03-16
AR009013A1 (es) 2000-03-08
DE69717463D1 (de) 2003-01-09
CA2262582A1 (en) 1998-02-12
US20010006940A1 (en) 2001-07-05
WO1998005353A1 (en) 1998-02-12
PT920330E (pt) 2003-02-28
DK0920330T3 (da) 2002-12-30
IL128399A (en) 2006-10-05
JP3996952B2 (ja) 2007-10-24
ITRM960566A0 (de) 1996-08-07
DE69717463T2 (de) 2003-07-10
EP0920330B1 (de) 2002-11-27
EP0920330A1 (de) 1999-06-09
ITRM960566A1 (it) 1998-02-07
IT1284876B1 (it) 1998-05-22

Similar Documents

Publication Publication Date Title
DE69725465D1 (de) 6-phenylpyridyl-2-amin-derivate verwendbar als nos-inhibitoren
DE69718480D1 (de) Heterocyclische metalloprotease inhibitoren
EE9900171A (et) Heteroarüülsuktsiinamiidid ja nende kasutamine metalloproteinaaside inhibiitoritena
DE69836346D1 (de) Heteroaryl aminoguanidin- und alkoxyguanidinderivate und ihre verwendung als proteasehemmer
DK0923561T3 (da) Heterocykliske metalloproteaseinhibitorer
DE69820906D1 (de) Hydroxamsäure-derivate als matrix metalloproteinaseinhibitoren
NO972307D0 (no) Matriksmetallproteaseinhibitorer
FI990466A0 (fi) Aktivaattorit ja laite
DE69826662D1 (de) 4-brom or 4-iod-phenylamino-benzhydroxamsäurederivate und ihre anwendung als mek-inhibitoren
DE60020100D1 (de) Dimerverbindungen und als inhibitoren der neuramidinase
ATE214693T1 (de) Aminoguanidine und alkoxyguanidine als protease- hemmer
DK0927183T3 (da) Spirocykliske metalloprotease-inhibitorer
FI973198L (fi) Silloitetut indolit matriisimetalloproteaasi-inhibiittoreina
NO985227D0 (no) Alkylaminobenzothiazol og -benzoksazol - derivater
BR9709902A (pt) Inibidores de metalo-proteinase de matriz
DE69702751D1 (de) Dipeptidische benzamidine als kininogenasen-inhibitoren
HUP9904165A3 (en) 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase and use thereof
ATE210112T1 (de) Substituierte 4-biphenyl-4- hydroxybuttersäurederivate als matrix metallprotease inhibitoren
DE69708629D1 (de) Alkyloxyamin-substituierte fluorenonderivate und ihre verwendung als proteinkinase-c-inhibitoren
ATE228372T1 (de) Hcg und derivate als matrixmetalloprotease- inhibitoren
ATE205822T1 (de) Substituierte 4-arylbutyrsäurederivate als matrix metalloprotease inhibitoren
ATE229497T1 (de) Substituierte phenethyl-derivate als matrx- metalloprotease-inhibitoren
DE69831427D1 (de) Benzo(c)quinolizinderivative und deren verwendung als 5 alpha-reduktase-hemmer
EE04494B1 (et) 1-oksa-, asa- ja tianaftaleen-2-oon biseetrid fosfolambaani inhibiitoritena
DE69809829D1 (de) Untergrunderkennung und Kompensation

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0920330

Country of ref document: EP

EEFA Change of the company name