ATE22879T1 - Pharmazeutische zusammensetzungen und verfahren zu deren herstellung. - Google Patents

Pharmazeutische zusammensetzungen und verfahren zu deren herstellung.

Info

Publication number: ATE22879T1
Authority: AT; Austria
Prior art keywords: ulcerogenic; oleanolic acid; disorders; provides; manufacture
Prior art date: 1982-04-27

Application number

AT83302068T

Other languages

English (en)

Inventor

Friedrich Otto Snyckers

Theunis Gerhardus Fourie

Original Assignee

Noristan Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-04-27

Filing date

1983-04-13

Publication date

1986-11-15

1983-04-13 Application filed by Noristan Ltd filed Critical Noristan Ltd

1986-11-15 Application granted granted Critical

1986-11-15 Publication of ATE22879T1 publication Critical patent/ATE22879T1/de

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 abstract 3
JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 abstract 3
YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 abstract 3
MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 abstract 3
229940100243 oleanolic acid Drugs 0.000 abstract 3
HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
210000000936 intestine Anatomy 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
210000002784 stomach Anatomy 0.000 abstract 2
230000000202 analgesic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000001562 ulcerogenic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT83302068T 1982-04-27 1983-04-13 Pharmazeutische zusammensetzungen und verfahren zu deren herstellung. ATE22879T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ZA822847		1982-04-27

Publications (1)

Publication Number	Publication Date
ATE22879T1 true ATE22879T1 (de)	1986-11-15

Family

ID=25576040

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT83302068T ATE22879T1 (de)	1982-04-27	1983-04-13	Pharmazeutische zusammensetzungen und verfahren zu deren herstellung.

Country Status (7)

Country	Link
US (1)	US4752606A (de)
EP (1)	EP0093520B1 (de)
JP (1)	JPS58201713A (de)
AT (1)	ATE22879T1 (de)
AU (1)	AU569840B2 (de)
CA (1)	CA1216796A (de)
DE (1)	DE3366910D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6236330A (ja) *	1985-08-12	1987-02-17	Oyo Seikagaku Kenkyusho:Kk	センブリ抽出エキス及びその製法
FR2609633B1 (fr) *	1987-01-15	1991-03-29	Froment Suzanne	Utilisation de l'acide glycyrrhetinique en tant que moyen cicatrisant
JPH07583B2 (ja) *	1990-11-21	1995-01-11	北海道糖業株式会社	水溶性五環性トリテルペン包接化合物及びその製造方法並びにそれを利用した食品、飲料、口腔用組成物
WO1993000895A1 (fr) *	1991-07-04	1993-01-21	Taisho Pharmaceutical Co., Ltd.	Analgesique
ZA976189B (en) *	1996-07-12	1999-01-11	Novartis Consumer Health Sa	Oral pharmaceutical combinations
ES2111498B1 (es) *	1996-07-25	1998-09-01	Univ Granada	Procedimiento de aprovechamiento industrial de los acidos oleanolico y maslinico contenidos en los subproductos de la molturacion de la aceituna.
ES2160553B1 (es) *	2000-04-19	2002-06-01	Consejo Superior Investigacion	Procedimiento para la obtencion de acidos terpenicos a partir de hoja de olea europaea.
DE60114708T2 (de) *	2000-06-05	2006-07-20	Loders Croklaan B.V.	Ursolsäure und Oleanolsäure enthaltende Mischungen
JPWO2003029391A1 (ja) *	2001-09-28	2005-01-13	日清オイリオグループ株式会社	オレアノール酸および／またはマスリン酸を含有する油脂組成物の製造方法
US20080220104A1 (en) *	2007-03-08	2008-09-11	Cappello John V	Compositions for producing satiety
RU2472231C1 (ru) *	2011-06-16	2013-01-10	Государственное образовательное учреждение высшего профессионального образования "Саратовский государственный университет им. Н.Г. Чернышевского"	Способ экспериментального моделирования стресс-индуцированного развития острого язвенного кровотечения

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3070623A (en) *	1957-07-16	1962-12-25	Biorex Laboratories Ltd	Pharmacological compounds
FR3715M (fr) *	1964-06-11	1965-11-29	Lucien Nouvel	Antithermiques et antirhumatismaux améliorés.
US3350270A (en) *	1964-09-18	1967-10-31	Leeds Dixon Lab Inc	Aluminum aspirin film-enveloped therapeutic agents in sustained release dosage form
GB1205012A (en) *	1966-09-19	1970-09-09	Dott Inverni & Della Beffa S P	Pharmaceutically active triterpenic acid
GB1251977A (de) *	1968-08-08	1971-11-03
GB1251976A (de) *	1968-08-08	1971-11-03
US3766206A (en) *	1971-11-03	1973-10-16	Pfizer	18beta-glycyrrheting acid amides useful as antiulcer agents
US3859328A (en) *	1971-11-03	1975-01-07	Pfizer	18 beta-glycyrrhetinic acid amides
GB1445831A (en) *	1972-08-22	1976-08-11	Boissevain L R	Pharmaceutically active derivatives of glycyrrhizinic acid and their preparation
GB1390683A (en) *	1972-12-18	1975-04-16	Biorex Laboratories Ltd	Pharmaceutical composition
US3934027A (en) *	1973-05-03	1976-01-20	Pfizer Inc.	18β-Glycyrrhetinic acid amides useful as antiulcer agents
GB1493926A (en) *	1974-01-29	1977-11-30	Inverni Della Beffa Spa	Pentacyclic triterpenes obtainable from terminalia sericea and their derivatives
DE2708520A1 (de) *	1977-02-26	1978-08-31	Thomae Gmbh Dr K	Neue arzneimittelkombinationen und verfahren zu ihrer herstellung
IT1075675B (it) *	1977-03-16	1985-04-22	Isf Spa	Derivati dell'acido oleanoico
NZ191586A (en) *	1978-10-10	1981-10-19	Sterling Drug Inc	Cyanoketones derived from glycyrrhetinic acid and pharmaceutical compositions
US4378354A (en) *	1978-12-27	1983-03-29	A. Nattermann & Cie. Gmbh	Inflammation-preventing pharmaceutical composition of oral administration
US4228161A (en) *	1979-03-28	1980-10-14	Merck & Co., Inc.	Anti-inflammatory combination having reduced ulcerogenicity
IT1167857B (it) *	1980-04-01	1987-05-20	Minophagen Pharma Co	Agente antiulcera,antiinfiammatorio ed antiallergico comprendente come ingrediente principale olean-12-ene-3beta,30-diolo e preparazione di esso

1983
- 1983-04-13 EP EP83302068A patent/EP0093520B1/de not_active Expired
- 1983-04-13 AT AT83302068T patent/ATE22879T1/de not_active IP Right Cessation
- 1983-04-13 DE DE8383302068T patent/DE3366910D1/de not_active Expired
- 1983-04-19 CA CA000426170A patent/CA1216796A/en not_active Expired
- 1983-04-26 AU AU13955/83A patent/AU569840B2/en not_active Ceased
- 1983-04-26 JP JP58073705A patent/JPS58201713A/ja active Pending
1984
- 1984-09-14 US US07/650,574 patent/US4752606A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA1216796A (en)	1987-01-20
US4752606A (en)	1988-06-21
EP0093520B1 (de)	1986-10-15
AU1395583A (en)	1983-11-03
DE3366910D1 (en)	1986-11-20
AU569840B2 (en)	1988-02-25
EP0093520A1 (de)	1983-11-09
JPS58201713A (ja)	1983-11-24

Legal Events

Date	Code	Title	Description
1987-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
GR1000465B (el)	1992-07-30	Μεθοδος παρασκευης φαρμακευτικων συνθεσεων που περιεχουν ακετυλ d-καρνιτινη για την θεραπευτικη αγωγη του γλαυκωματος.
MA23170A1 (fr)	1994-12-31	Procede de preparation d'un nouveau compose .
DE69933208D1 (de)	2006-10-26	Verwendung von zusammensetzungen mit antiseptika und/oder die wundheilung fördernden wirkstoffen für den tieferen atemwegstrakt
GB2303629B (en)	1998-09-02	Hydroxamic acids and their use as metalloproteinase inhibitors
UA37196C2 (uk)	2001-05-15	Лікарська форма для перорального введення для лікування запальних хвороб кишкового тракту
MX163955B (es)	1992-07-06	Composicion farmaceutica de dihidrocodeina e ibuprofen
CA2302700A1 (en)	1999-04-01	New use for budesonide and formoterol
ATE22879T1 (de)	1986-11-15	Pharmazeutische zusammensetzungen und verfahren zu deren herstellung.
DE69429964D1 (de)	2002-04-04	Feste, therapeutische oder hygienische, mucoadhäsive Zusammensetzung zur Verabreichung durch Auftragen auf der Mund-schleimhaut oder der Nasen-schleimhaut
IT1170214B (it)	1987-06-03	Composizione farmaceutica per la cura delle arteriopatie periferiche
MY108146A (en)	1996-08-30	Medicaments for treating inflammatory conditions or for analgesia
IS4251A (is)	1995-08-12	Ný píperídín-4-karboxamíð sem hafa kvalastillandiog staðdeyfandi áhrif
BR0207866A (pt)	2004-03-23	Uso de flumazenil na preparação de um medicamento para o tratamento da dependência de cocaìna
ATE91890T1 (de)	1993-08-15	Herstellung eines arzneimittels gegen arthritis und rheumatismus.
IL70407A (en)	1990-03-19	Synergistic analgesic pharmaceutical compositions in unit dosage form,comprising an analgesic agent and hydroxyzine
SE8304818D0 (sv)	1983-09-08	A medicine having anti-ulcer, spasmolytic and locally anesthetic effect
MY110416A (en)	1998-05-30	Composition for the treatment of schizophrenia.
IT1150451B (it)	1986-12-10	Composizione farmaceutica ad attivita'analgesica,antiretica e antiinfiammatoria e procedimento per la preparazione del principio attivo