ATE229340T1 - Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen - Google Patents

Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen

Info

Publication number
ATE229340T1
ATE229340T1 AT96920364T AT96920364T ATE229340T1 AT E229340 T1 ATE229340 T1 AT E229340T1 AT 96920364 T AT96920364 T AT 96920364T AT 96920364 T AT96920364 T AT 96920364T AT E229340 T1 ATE229340 T1 AT E229340T1
Authority
AT
Austria
Prior art keywords
related methods
relaxing factor
factor
relaxin
analogs
Prior art date
Application number
AT96920364T
Other languages
English (en)
Inventor
Christian Schwabe
Elaine Unemori
Original Assignee
Connective Therapeutics Inc
Univ South Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connective Therapeutics Inc, Univ South Carolina filed Critical Connective Therapeutics Inc
Application granted granted Critical
Publication of ATE229340T1 publication Critical patent/ATE229340T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT96920364T 1995-06-07 1996-05-16 Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen ATE229340T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/484,219 US5911997A (en) 1995-06-07 1995-06-07 Relaxin-like factor and methods and uses thereof
PCT/US1996/007399 WO1996040186A1 (en) 1995-06-07 1996-05-16 Relaxin-like factor and methods and uses thereof

Publications (1)

Publication Number Publication Date
ATE229340T1 true ATE229340T1 (de) 2002-12-15

Family

ID=23923245

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96920364T ATE229340T1 (de) 1995-06-07 1996-05-16 Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen

Country Status (9)

Country Link
US (2) US5911997A (de)
EP (1) EP0831871B1 (de)
JP (1) JP3830520B2 (de)
AT (1) ATE229340T1 (de)
AU (1) AU709115B2 (de)
CA (1) CA2224080C (de)
DE (1) DE69625354T2 (de)
ES (1) ES2188763T3 (de)
WO (1) WO1996040186A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2229479C (en) 1995-08-15 2010-03-30 Connective Therapeutics, Inc. Method of promoting angiogenesis
DE19641378C1 (de) * 1996-09-27 1998-04-02 Ihf Inst Fuer Hormon Und Fortp Diagnosehilfe sowie Verfahren zum Nachweis der Trächtigkeit von Wiederkäuern
GB9717652D0 (en) * 1997-08-20 1997-10-22 Nycomed Imaging As Method
AUPR814401A0 (en) 2001-10-08 2001-11-01 Howard Florey Institute Of Experimental Physiology And Medicine Human 3 relaxin
US20050186526A1 (en) * 2002-11-01 2005-08-25 Bas Medical, Inc. Methods and systems for enabling and stabilizing tooth movement
AU2003903124A0 (en) * 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
US7878978B2 (en) * 2004-03-18 2011-02-01 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Use of relaxin to increase arterial compliance
JP4836942B2 (ja) * 2004-04-30 2011-12-14 コーセラ， インコーポレイテッド リラキシンの調節による胎仔の発育の制御のための方法および組成物
US20060052304A1 (en) * 2004-09-02 2006-03-09 Bas Medical, Inc. Method for remodeling bone and related sutures
EP1984016A1 (de) * 2006-02-17 2008-10-29 Associazione Foresta Per La Ricerca Nella Riproduzione Umana Verwendung von insulin-artigem faktor 3 zur behandlung von osteoporose und knochenerkrankungen
BRPI0920897A2 (pt) * 2008-11-24 2015-12-29 Corthera Inc prognóstico e prevenção de pré-eclampsia
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
EA030886B1 (ru) 2010-08-17 2018-10-31 Амбркс, Инк. Модифицированные полипептиды релаксина, содержащие некодируемую в природе аминокислоту, связанную с полимером, и их применение
JP6276690B2 (ja) * 2011-08-04 2018-02-07 ファリス バイオテック ゲーエムベーハー ヒトリラキシン−２を調製する方法
WO2013177529A1 (en) * 2012-05-24 2013-11-28 Angion Biomedica Corp. Relaxin-like compounds and uses thereof
US9393288B2 (en) 2012-05-29 2016-07-19 The University Of Vermont And State Agricultural College Methods of treating diseases associated with PPARγ
WO2014040008A1 (en) * 2012-09-10 2014-03-13 Angion Biomedica Corp. Relaxin-like peptides and uses thereof
JP6822839B2 (ja) 2013-09-13 2021-01-27 ザ・スクリップス・リサーチ・インスティテュート 修飾された治療剤、及びその組成物
KR102455171B1 (ko) 2013-12-18 2022-10-14 더 스크립스 리서치 인스티튜트 변형된 치료제, 스테이플드 펩티드 지질 접합체, 및 이의 조성물
MA41794A (fr) * 2015-03-18 2018-01-23 The California Institute For Biomedical Res Agents thérapeutiques modifiés et compositions associées
PT3387019T (pt) 2015-12-09 2022-01-14 Scripps Research Inst Proteínas de fusão de imunoglobulina de relaxina e métodos de uso
PE20191716A1 (es) 2017-02-08 2019-12-05 Bristol Myers Squibb Co Polipeptidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos
MX2022006861A (es) 2019-12-04 2022-07-11 Scripps Research Inst Agonistas del receptor glp2 y metodos de uso.
KR20240032010A (ko) 2021-06-09 2024-03-08 더 스크립스 리서치 인스티튜트 장기 지속형 이중 gip/glp-1 펩타이드 접합체 및 사용 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0101309B1 (de) * 1982-08-12 1991-01-16 Howard Florey Institute Of Experimental Physiology And Medicine Molekulare Klonierung und Charakterisierung der das menschliche Relaxin kodierenden Gen-Sequenz
US4835251A (en) * 1986-06-23 1989-05-30 Genetech, Inc. Method of chain combination
US5478807A (en) * 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy

Also Published As

Publication number Publication date
DE69625354T2 (de) 2003-10-30
EP0831871A4 (de) 1999-03-03
CA2224080C (en) 2010-07-27
US6949506B2 (en) 2005-09-27
EP0831871A1 (de) 1998-04-01
DE69625354D1 (de) 2003-01-23
US5911997A (en) 1999-06-15
AU709115B2 (en) 1999-08-19
JP3830520B2 (ja) 2006-10-04
US20030158376A1 (en) 2003-08-21
AU5869996A (en) 1996-12-30
EP0831871B1 (de) 2002-12-11
CA2224080A1 (en) 1996-12-19
JPH11512072A (ja) 1999-10-19
ES2188763T3 (es) 2003-07-01
WO1996040186A1 (en) 1996-12-19

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