ATE229343T1 - Kombination von temozolomide und alpha-interferon zur behandlung von fortgeschrittenem krebs - Google Patents
Kombination von temozolomide und alpha-interferon zur behandlung von fortgeschrittenem krebsInfo
- Publication number
- ATE229343T1 ATE229343T1 AT96935971T AT96935971T ATE229343T1 AT E229343 T1 ATE229343 T1 AT E229343T1 AT 96935971 T AT96935971 T AT 96935971T AT 96935971 T AT96935971 T AT 96935971T AT E229343 T1 ATE229343 T1 AT E229343T1
- Authority
- AT
- Austria
- Prior art keywords
- temozolomide
- combination
- treatment
- alpha interferon
- advanced cancer
- Prior art date
Links
- 102000006992 Interferon-alpha Human genes 0.000 title abstract 2
- 108010047761 Interferon-alpha Proteins 0.000 title abstract 2
- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical compound O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 229960004964 temozolomide Drugs 0.000 title abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US623395P | 1995-10-04 | 1995-10-04 | |
| US62541096A | 1996-03-27 | 1996-03-27 | |
| PCT/US1996/015413 WO1997012630A1 (en) | 1995-10-04 | 1996-10-01 | Combination of temozolomide and alpha-ifn for the treatment of advanced cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE229343T1 true ATE229343T1 (de) | 2002-12-15 |
Family
ID=26675350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96935971T ATE229343T1 (de) | 1995-10-04 | 1996-10-01 | Kombination von temozolomide und alpha-interferon zur behandlung von fortgeschrittenem krebs |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0859630B1 (de) |
| JP (2) | JP4156028B2 (de) |
| AT (1) | ATE229343T1 (de) |
| AU (1) | AU719074B2 (de) |
| CA (1) | CA2233544A1 (de) |
| DE (1) | DE69625373T2 (de) |
| DK (1) | DK0859630T3 (de) |
| ES (1) | ES2183977T3 (de) |
| PT (1) | PT859630E (de) |
| WO (1) | WO1997012630A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102160864A (zh) * | 1999-03-30 | 2011-08-24 | 先灵公司 | 用替莫唑胺改善癌症治疗 |
| CA2397793A1 (en) * | 2000-01-24 | 2001-07-26 | Schering Corporation | Combination of temozolomide and pegylated interferon-alpha for treating cancer |
| EP1908477A3 (de) * | 2000-01-24 | 2008-06-11 | Schering Corporation | Kombination aus Temozolomid und pegyliertem Interferon-alpha zur Krebsbehandlung |
| JP5208733B2 (ja) | 2005-06-29 | 2013-06-12 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 組換えインターフェロンα２（ＩＦＮα２）変異体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5017371A (en) * | 1988-01-06 | 1991-05-21 | Amarillo Cell Culture Company, Incorporated | Method for reducing side effects of cancer therapy |
| ATE92333T1 (de) * | 1988-12-01 | 1993-08-15 | Schering Corp | Arzneimittel zur intralesionsbehandlung von schuppenartigem zellkarzinomen mit rekombinantem human-alpha-interferon. |
| AU651998B2 (en) * | 1990-10-12 | 1994-08-11 | F. Hoffmann-La Roche Ag | Use of a retinoid |
| DE4244548C2 (de) * | 1992-12-30 | 1997-10-02 | Stockhausen Chem Fab Gmbh | Pulverförmige, unter Belastung wäßrige Flüssigkeiten sowie Blut absorbierende Polymere, Verfahren zu ihrer Herstellung und ihre Verwendung in textilen Konstruktionen für die Körperhygiene |
-
1996
- 1996-10-01 DE DE69625373T patent/DE69625373T2/de not_active Expired - Lifetime
- 1996-10-01 AU AU73731/96A patent/AU719074B2/en not_active Ceased
- 1996-10-01 EP EP96935971A patent/EP0859630B1/de not_active Expired - Lifetime
- 1996-10-01 JP JP51432197A patent/JP4156028B2/ja not_active Expired - Fee Related
- 1996-10-01 WO PCT/US1996/015413 patent/WO1997012630A1/en not_active Ceased
- 1996-10-01 ES ES96935971T patent/ES2183977T3/es not_active Expired - Lifetime
- 1996-10-01 PT PT96935971T patent/PT859630E/pt unknown
- 1996-10-01 AT AT96935971T patent/ATE229343T1/de active
- 1996-10-01 CA CA002233544A patent/CA2233544A1/en not_active Abandoned
- 1996-10-01 DK DK96935971T patent/DK0859630T3/da active
-
2007
- 2007-03-26 JP JP2007080381A patent/JP2007169300A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11514995A (ja) | 1999-12-21 |
| JP2007169300A (ja) | 2007-07-05 |
| EP0859630A1 (de) | 1998-08-26 |
| JP4156028B2 (ja) | 2008-09-24 |
| AU719074B2 (en) | 2000-05-04 |
| WO1997012630A1 (en) | 1997-04-10 |
| PT859630E (pt) | 2003-02-28 |
| DE69625373T2 (de) | 2003-05-15 |
| ES2183977T3 (es) | 2003-04-01 |
| DK0859630T3 (da) | 2003-03-24 |
| AU7373196A (en) | 1997-04-28 |
| CA2233544A1 (en) | 1997-04-10 |
| DE69625373D1 (de) | 2003-01-23 |
| EP0859630B1 (de) | 2002-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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