ATE229519T1 - Neue cis-3,4-chromanderivate zur vorbeugung oder behandlung von oestrogenbezogenen krankheiten oder syndromen - Google Patents

Neue cis-3,4-chromanderivate zur vorbeugung oder behandlung von oestrogenbezogenen krankheiten oder syndromen

Info

Publication number
ATE229519T1
ATE229519T1 AT97910267T AT97910267T ATE229519T1 AT E229519 T1 ATE229519 T1 AT E229519T1 AT 97910267 T AT97910267 T AT 97910267T AT 97910267 T AT97910267 T AT 97910267T AT E229519 T1 ATE229519 T1 AT E229519T1
Authority
AT
Austria
Prior art keywords
syndromes
prevention
treatment
related diseases
estrogen
Prior art date
Application number
AT97910267T
Other languages
English (en)
Inventor
Poul Jacobsen
Svend Treppendahl
Paul Stanley Bury
Anders Kanstrup
Lise Brown Christiansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE229519T1 publication Critical patent/ATE229519T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT97910267T 1996-10-28 1997-10-28 Neue cis-3,4-chromanderivate zur vorbeugung oder behandlung von oestrogenbezogenen krankheiten oder syndromen ATE229519T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK119596 1996-10-28
PCT/DK1997/000486 WO1998018779A1 (en) 1996-10-28 1997-10-28 Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes

Publications (1)

Publication Number Publication Date
ATE229519T1 true ATE229519T1 (de) 2002-12-15

Family

ID=8102047

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97910267T ATE229519T1 (de) 1996-10-28 1997-10-28 Neue cis-3,4-chromanderivate zur vorbeugung oder behandlung von oestrogenbezogenen krankheiten oder syndromen

Country Status (12)

Country Link
EP (1) EP0937062B1 (de)
JP (1) JP2001502711A (de)
AT (1) ATE229519T1 (de)
AU (1) AU4772397A (de)
CA (1) CA2269973A1 (de)
DE (1) DE69717844T2 (de)
DK (1) DK0937062T3 (de)
ES (1) ES2188909T3 (de)
IL (1) IL129627A0 (de)
NO (1) NO992006L (de)
WO (1) WO1998018779A1 (de)
ZA (1) ZA979650B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002533456A (ja) * 1998-12-30 2002-10-08 シグナル ファーマシューティカルズ， インコーポレイテッド エストロゲン受容体のモジュレートを行うための化合物および方法
ATE532777T1 (de) 2004-09-21 2011-11-15 Marshall Edwards Inc Substituierte chromanderivate, medikamente und anwendungen in der therapie
JP4976649B2 (ja) * 2004-09-21 2012-07-18 マーシャル エドワーズ，インク． 化合物
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
CA2816322A1 (en) 2010-11-01 2012-05-10 Marshall Edwards, Inc. Isoflavonoid compositions and methods for the treatment of cancer
CN107427003B (zh) 2015-02-02 2023-01-31 梅制药公司 联合治疗
WO2019051562A1 (en) * 2017-09-15 2019-03-21 Norbio No. 1 Pty Ltd TREATMENT OF EXCITOTOXICITY
EP4420728A3 (de) * 2019-12-12 2024-10-30 Accutar Biotechnology Inc. Neue chromanderivate mit östrogenrezeptorabbauaktivität und verwendungen davon

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340276A (en) * 1964-04-01 1967-09-05 Ciba Geigy Corp 3, 4-diphenyl-chromans
DE1543749A1 (de) * 1966-02-16 1969-12-11 Merck Ag E Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
HUP9702244A3 (en) * 1995-01-13 1999-12-28 Novo Nordisk As Use of 3,4-diphenyl chromans for manufacture of a pharmaceutical composition for treatment or prophylaxis of gynaecological disorders

Also Published As

Publication number Publication date
NO992006D0 (no) 1999-04-27
DE69717844D1 (de) 2003-01-23
ES2188909T3 (es) 2003-07-01
ZA979650B (en) 1998-04-28
WO1998018779A1 (en) 1998-05-07
IL129627A0 (en) 2000-02-29
AU4772397A (en) 1998-05-22
CA2269973A1 (en) 1998-05-07
EP0937062A1 (de) 1999-08-25
DK0937062T3 (da) 2003-04-07
EP0937062B1 (de) 2002-12-11
DE69717844T2 (de) 2003-10-02
NO992006L (no) 1999-06-25
JP2001502711A (ja) 2001-02-27

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