ATE231721T1 - Verwendung von tropolon derivate zur hemmung des inositmono phosphatase - Google Patents

Verwendung von tropolon derivate zur hemmung des inositmono phosphatase

Info

Publication number
ATE231721T1
ATE231721T1 AT96916132T AT96916132T ATE231721T1 AT E231721 T1 ATE231721 T1 AT E231721T1 AT 96916132 T AT96916132 T AT 96916132T AT 96916132 T AT96916132 T AT 96916132T AT E231721 T1 ATE231721 T1 AT E231721T1
Authority
AT
Austria
Prior art keywords
inositemono
phosphatase
inhibit
tropolone derivatives
tropolone
Prior art date
Application number
AT96916132T
Other languages
English (en)
Inventor
Khalid Islam
Stefania Stefanelli
Federica Sponga
Maurizio Denaro
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Application granted granted Critical
Publication of ATE231721T1 publication Critical patent/ATE231721T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT96916132T 1995-05-24 1996-05-20 Verwendung von tropolon derivate zur hemmung des inositmono phosphatase ATE231721T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95107936 1995-05-24
PCT/EP1996/002160 WO1996037197A1 (en) 1995-05-24 1996-05-20 Use of tropolone derivatives as inhibitors of the enzyme inositol monophosphatase

Publications (1)

Publication Number Publication Date
ATE231721T1 true ATE231721T1 (de) 2003-02-15

Family

ID=8219287

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96916132T ATE231721T1 (de) 1995-05-24 1996-05-20 Verwendung von tropolon derivate zur hemmung des inositmono phosphatase

Country Status (13)

Country Link
US (1) US5990160A (de)
EP (1) EP0828483B1 (de)
JP (1) JP4054061B2 (de)
KR (2) KR100412753B1 (de)
AT (1) ATE231721T1 (de)
AU (1) AU698059B2 (de)
CA (1) CA2221771C (de)
DE (1) DE69626010T2 (de)
DK (1) DK0828483T3 (de)
ES (1) ES2186782T3 (de)
PT (1) PT828483E (de)
SI (1) SI0828483T1 (de)
WO (1) WO1996037197A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689342B1 (en) * 2002-07-29 2004-02-10 Warner-Lambert Company Oral care compositions comprising tropolone compounds and essential oils and methods of using the same
GB201102248D0 (en) 2011-02-09 2011-03-23 Isis Innovation Treatment of bipolar disorder

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56147704A (en) * 1980-04-07 1981-11-16 Rowaale Keshohin Kk Dermatological composition
US4981980A (en) * 1989-09-14 1991-01-01 Merck & Co., Inc. Drug for treating manic depression

Also Published As

Publication number Publication date
DE69626010T2 (de) 2003-07-24
KR19990021882A (ko) 1999-03-25
PT828483E (pt) 2003-06-30
US5990160A (en) 1999-11-23
ES2186782T3 (es) 2003-05-16
CA2221771C (en) 2007-09-18
AU698059B2 (en) 1998-10-22
JPH11505817A (ja) 1999-05-25
KR100412753B1 (ko) 2004-04-21
KR20040004513A (ko) 2004-01-13
WO1996037197A1 (en) 1996-11-28
EP0828483B1 (de) 2003-01-29
DE69626010D1 (de) 2003-03-06
JP4054061B2 (ja) 2008-02-27
AU5900096A (en) 1996-12-11
CA2221771A1 (en) 1996-11-28
EP0828483A1 (de) 1998-03-18
SI0828483T1 (en) 2003-06-30
DK0828483T3 (da) 2003-05-19

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