ATE231721T1 - Verwendung von tropolon derivate zur hemmung des inositmono phosphatase - Google Patents
Verwendung von tropolon derivate zur hemmung des inositmono phosphataseInfo
- Publication number
- ATE231721T1 ATE231721T1 AT96916132T AT96916132T ATE231721T1 AT E231721 T1 ATE231721 T1 AT E231721T1 AT 96916132 T AT96916132 T AT 96916132T AT 96916132 T AT96916132 T AT 96916132T AT E231721 T1 ATE231721 T1 AT E231721T1
- Authority
- AT
- Austria
- Prior art keywords
- inositemono
- phosphatase
- inhibit
- tropolone derivatives
- tropolone
- Prior art date
Links
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 title 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 title 1
- MDYOLVRUBBJPFM-UHFFFAOYSA-N tropolone Chemical class OC1=CC=CC=CC1=O MDYOLVRUBBJPFM-UHFFFAOYSA-N 0.000 title 1
- RRDGXYZZWSIADF-UHFFFAOYSA-N puberulic acid Chemical compound OC(=O)C=1C=C(O)C(O)=C(O)C(=O)C=1 RRDGXYZZWSIADF-UHFFFAOYSA-N 0.000 abstract 2
- JAJRKOVXTSKCLS-UHFFFAOYSA-N puberulonic acid Chemical compound C1=C(O)C(=O)C(O)=C(O)C2=C1C(=O)OC2=O JAJRKOVXTSKCLS-UHFFFAOYSA-N 0.000 abstract 2
- 206010054089 Depressive symptom Diseases 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102100021608 Inositol monophosphatase 2 Human genes 0.000 abstract 1
- 206010026749 Mania Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95107936 | 1995-05-24 | ||
| PCT/EP1996/002160 WO1996037197A1 (en) | 1995-05-24 | 1996-05-20 | Use of tropolone derivatives as inhibitors of the enzyme inositol monophosphatase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE231721T1 true ATE231721T1 (de) | 2003-02-15 |
Family
ID=8219287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96916132T ATE231721T1 (de) | 1995-05-24 | 1996-05-20 | Verwendung von tropolon derivate zur hemmung des inositmono phosphatase |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5990160A (de) |
| EP (1) | EP0828483B1 (de) |
| JP (1) | JP4054061B2 (de) |
| KR (2) | KR20040004513A (de) |
| AT (1) | ATE231721T1 (de) |
| AU (1) | AU698059B2 (de) |
| CA (1) | CA2221771C (de) |
| DE (1) | DE69626010T2 (de) |
| DK (1) | DK0828483T3 (de) |
| ES (1) | ES2186782T3 (de) |
| PT (1) | PT828483E (de) |
| SI (1) | SI0828483T1 (de) |
| WO (1) | WO1996037197A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6689342B1 (en) * | 2002-07-29 | 2004-02-10 | Warner-Lambert Company | Oral care compositions comprising tropolone compounds and essential oils and methods of using the same |
| GB201102248D0 (en) | 2011-02-09 | 2011-03-23 | Isis Innovation | Treatment of bipolar disorder |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56147704A (en) * | 1980-04-07 | 1981-11-16 | Rowaale Keshohin Kk | Dermatological composition |
| US4981980A (en) * | 1989-09-14 | 1991-01-01 | Merck & Co., Inc. | Drug for treating manic depression |
-
1996
- 1996-05-20 DE DE69626010T patent/DE69626010T2/de not_active Expired - Lifetime
- 1996-05-20 DK DK96916132T patent/DK0828483T3/da active
- 1996-05-20 ES ES96916132T patent/ES2186782T3/es not_active Expired - Lifetime
- 1996-05-20 EP EP96916132A patent/EP0828483B1/de not_active Expired - Lifetime
- 1996-05-20 KR KR10-2003-7009874A patent/KR20040004513A/ko not_active Ceased
- 1996-05-20 PT PT96916132T patent/PT828483E/pt unknown
- 1996-05-20 WO PCT/EP1996/002160 patent/WO1996037197A1/en not_active Ceased
- 1996-05-20 SI SI9630569T patent/SI0828483T1/xx unknown
- 1996-05-20 CA CA002221771A patent/CA2221771C/en not_active Expired - Lifetime
- 1996-05-20 AT AT96916132T patent/ATE231721T1/de active
- 1996-05-20 AU AU59000/96A patent/AU698059B2/en not_active Expired
- 1996-05-20 JP JP53536896A patent/JP4054061B2/ja not_active Expired - Lifetime
- 1996-05-20 KR KR1019970708357A patent/KR100412753B1/ko not_active Expired - Lifetime
-
1999
- 1999-05-14 US US09/312,733 patent/US5990160A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0828483B1 (de) | 2003-01-29 |
| KR100412753B1 (ko) | 2004-04-21 |
| AU5900096A (en) | 1996-12-11 |
| SI0828483T1 (en) | 2003-06-30 |
| JPH11505817A (ja) | 1999-05-25 |
| JP4054061B2 (ja) | 2008-02-27 |
| KR19990021882A (ko) | 1999-03-25 |
| AU698059B2 (en) | 1998-10-22 |
| DE69626010T2 (de) | 2003-07-24 |
| ES2186782T3 (es) | 2003-05-16 |
| CA2221771C (en) | 2007-09-18 |
| DK0828483T3 (da) | 2003-05-19 |
| WO1996037197A1 (en) | 1996-11-28 |
| EP0828483A1 (de) | 1998-03-18 |
| US5990160A (en) | 1999-11-23 |
| DE69626010D1 (de) | 2003-03-06 |
| KR20040004513A (ko) | 2004-01-13 |
| CA2221771A1 (en) | 1996-11-28 |
| PT828483E (pt) | 2003-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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