ATE231868T1 - 5h-pyrano(2,3-d:6,5-d')dipyrimidin-derivate mit antibakterieller, antiviraler und immunmodulatorischer wirkung - Google Patents
5h-pyrano(2,3-d:6,5-d')dipyrimidin-derivate mit antibakterieller, antiviraler und immunmodulatorischer wirkungInfo
- Publication number
- ATE231868T1 ATE231868T1 AT97954962T AT97954962T ATE231868T1 AT E231868 T1 ATE231868 T1 AT E231868T1 AT 97954962 T AT97954962 T AT 97954962T AT 97954962 T AT97954962 T AT 97954962T AT E231868 T1 ATE231868 T1 AT E231868T1
- Authority
- AT
- Austria
- Prior art keywords
- antiviral
- antibacterial
- pyrano
- derivatives
- immunomodulatory effects
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 230000002519 immonomodulatory effect Effects 0.000 title abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU1997/000371 WO1999025718A1 (en) | 1997-11-19 | 1997-11-19 | 5H-PYRANO[2,3-d:6,5-d']DIPYRIMIDINE DERIVATIVES HAVING AN ANTIBACTERIAL, ANTIVIRAL AND IMMUNO-MODULATING ACTIVITY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE231868T1 true ATE231868T1 (de) | 2003-02-15 |
Family
ID=20130165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97954962T ATE231868T1 (de) | 1997-11-19 | 1997-11-19 | 5h-pyrano(2,3-d:6,5-d')dipyrimidin-derivate mit antibakterieller, antiviraler und immunmodulatorischer wirkung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6340755B1 (de) |
| EP (1) | EP1033369B1 (de) |
| JP (1) | JP2001523683A (de) |
| AT (1) | ATE231868T1 (de) |
| AU (1) | AU739701B2 (de) |
| CA (1) | CA2310398C (de) |
| DE (1) | DE69718831T2 (de) |
| IL (1) | IL136181A0 (de) |
| WO (1) | WO1999025718A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1309349B1 (de) * | 2000-07-07 | 2005-11-09 | Stichting REGA VZW | Pharmazeutische zusammensetzung und verfahren zur behandlung von retroviralen infektionen |
| GB0016845D0 (en) * | 2000-07-07 | 2000-08-30 | Leuven K U Res & Dev | Pharmaceutical composition for treatment of HIV infection |
| RU2232593C2 (ru) * | 2002-08-12 | 2004-07-20 | НИИ онкологии им. проф. Н.Н.Петрова | Способ лечения рака шейки матки ib-ii стадий |
| RU2246496C1 (ru) * | 2003-09-12 | 2005-02-20 | Тец Виктор Вениаминович | Вещество с противовирусной и антибактериальной активностью на основе производных 2,8-дитиоксо-1h-пирано[2,3-d, 6,5-d`] дипиримидина и их 10-аза-аналогов |
| RU2595038C1 (ru) * | 2015-04-03 | 2016-08-20 | Виктор Вениаминович Тец | Лекарственное средство с противовирусной активностью (варианты) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH485972A (fr) | 1968-11-01 | 1970-02-15 | Lucifer Sa | Valve servo-commandée à piston |
| SU487076A1 (ru) * | 1974-05-17 | 1975-10-05 | Киевский Ордена Ленина Государственный Университет Им.Т.Г. Шевченко | Способ получени солей производных пирилиа (2,3- ) пиримидина |
| US4272535A (en) * | 1978-07-31 | 1981-06-09 | Schering Corporation | 2,4-[1H,3H,5H]-(1)-Benzopyrano-[2,3-d]-pyrimidinediones and their use as anti-allergy agents |
| IE49570B1 (en) | 1979-03-30 | 1985-10-30 | Rhone Poulenc Ind | 2-(pyrid-2-yl)tetrahydrothiophene derivatives |
| US4297355A (en) * | 1979-11-15 | 1981-10-27 | Schering Corporation | (1H,3H,5H)-(1)-Benzopyrano-(2,3-d)-pyrimidine-4-one-2-thiones and their use as anti-allergy agents |
| DE3335472A1 (de) * | 1983-09-30 | 1985-04-11 | Gödecke AG, 1000 Berlin | 5h-(1)benzopyrano-(2,3,-d)pyrimidin-derivate, verfahren zu deren herstellung sowie deren verwendung bei der bekaempfung von gastralen und duodenalen schleimhautlaesionen |
| US5639881A (en) * | 1991-11-08 | 1997-06-17 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Synthesis and elucidation of pyrimido (4,5-Q) quinazoline derivatives |
| DE19502179A1 (de) * | 1995-01-25 | 1996-08-01 | Thomae Gmbh Dr K | Trisubstituierte Pyrimido[5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
-
1997
- 1997-11-19 IL IL13618197A patent/IL136181A0/xx unknown
- 1997-11-19 EP EP97954962A patent/EP1033369B1/de not_active Expired - Lifetime
- 1997-11-19 US US09/554,836 patent/US6340755B1/en not_active Expired - Fee Related
- 1997-11-19 AT AT97954962T patent/ATE231868T1/de not_active IP Right Cessation
- 1997-11-19 JP JP2000521099A patent/JP2001523683A/ja not_active Ceased
- 1997-11-19 WO PCT/RU1997/000371 patent/WO1999025718A1/ru not_active Ceased
- 1997-11-19 DE DE69718831T patent/DE69718831T2/de not_active Expired - Fee Related
- 1997-11-19 AU AU61257/98A patent/AU739701B2/en not_active Ceased
- 1997-11-19 CA CA002310398A patent/CA2310398C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2310398A1 (en) | 1999-05-27 |
| US6340755B1 (en) | 2002-01-22 |
| EP1033369A4 (de) | 2001-07-18 |
| AU6125798A (en) | 1999-06-07 |
| DE69718831T2 (de) | 2003-08-14 |
| IL136181A0 (en) | 2001-05-20 |
| EP1033369A1 (de) | 2000-09-06 |
| AU739701B2 (en) | 2001-10-18 |
| JP2001523683A (ja) | 2001-11-27 |
| CA2310398C (en) | 2006-10-24 |
| EP1033369B1 (de) | 2003-01-29 |
| WO1999025718A1 (en) | 1999-05-27 |
| DE69718831D1 (de) | 2003-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |