ATE232109T1 - Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendung - Google Patents
Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendungInfo
- Publication number
- ATE232109T1 ATE232109T1 AT94925121T AT94925121T ATE232109T1 AT E232109 T1 ATE232109 T1 AT E232109T1 AT 94925121 T AT94925121 T AT 94925121T AT 94925121 T AT94925121 T AT 94925121T AT E232109 T1 ATE232109 T1 AT E232109T1
- Authority
- AT
- Austria
- Prior art keywords
- muc
- tandem repeats
- derivatives
- peptides
- multiple tandem
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 101100346932 Mus musculus Muc1 gene Proteins 0.000 abstract 3
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4727—Mucins, e.g. human intestinal mucin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/099,354 US5744144A (en) | 1993-07-30 | 1993-07-30 | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
| PCT/US1994/008477 WO1995003825A1 (en) | 1993-07-30 | 1994-07-29 | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE232109T1 true ATE232109T1 (de) | 2003-02-15 |
Family
ID=22274597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94925121T ATE232109T1 (de) | 1993-07-30 | 1994-07-29 | Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5744144A (de) |
| EP (1) | EP0804231B1 (de) |
| JP (1) | JPH09501159A (de) |
| AT (1) | ATE232109T1 (de) |
| CA (1) | CA2167730A1 (de) |
| DE (1) | DE69432109T2 (de) |
| WO (1) | WO1995003825A1 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN568095A0 (en) * | 1995-09-27 | 1995-10-26 | Austin Research Institute, The | Anti-Galalpha(1,3)Gal antibody binding peptides |
| ES2309992T3 (es) * | 1995-10-20 | 2008-12-16 | University Of Nebraska Board Of Regents | Composiciones y procedimientos para incrementar las respuestas inmunes mediadas por celulas presentadoras de antigeno. |
| US20080286228A1 (en) * | 1995-10-20 | 2008-11-20 | Tarantolo Stefano R | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells |
| WO1997028187A2 (en) * | 1996-01-31 | 1997-08-07 | The Population Council | Multivalent chimeric peptides as microbicides |
| JP2001510440A (ja) * | 1996-03-20 | 2001-07-31 | スローン―ケタリング・インスティテュート・フォー・キャンサー・リサーチ | ムチン接合体ペプチドワクチン |
| AU2540897A (en) * | 1996-03-21 | 1997-10-10 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods and compositions of chimeric polypeptides for tumor antigen vaccines |
| US6514731B1 (en) | 1996-05-24 | 2003-02-04 | Chiron Corporation | Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens |
| JP3945822B2 (ja) * | 1996-05-24 | 2007-07-18 | カイロン コーポレイション | 複数エピトープ融合タンパク質 |
| JP2001501599A (ja) * | 1996-09-10 | 2001-02-06 | バイオミラ・インコーポレイテッド | 炎症性疾患および自己免疫疾患の治療のための免疫抑制治療薬としてのmuc―1 |
| JP2001502907A (ja) * | 1996-10-25 | 2001-03-06 | ダナ―ファーバー キャンサー インスティテュート インク. | ムチンが介在した免疫調節 |
| EP1012276A2 (de) | 1997-02-24 | 2000-06-28 | Therion Biologics Corporation | Rekombinantes poxvirus zur immunisierung gegen muc1 tumor-assoziiertes antigen |
| GB9810040D0 (en) | 1998-05-11 | 1998-07-08 | Univ Nottingham | Blood borne tumour markers |
| AU755017B2 (en) | 1998-06-26 | 2002-11-28 | Biomira Inc. | Method of detecting T-cell activation |
| AU773265B2 (en) * | 1998-11-05 | 2004-05-20 | Regents Of The University Of Michigan, The | S100 proteins and autoantibodies as serum markers for cancer |
| GB9827228D0 (en) * | 1998-12-10 | 1999-02-03 | Univ Nottingham | Cancer detection method and reagents |
| DE19906615A1 (de) * | 1999-02-17 | 2000-09-28 | Hanisch Franz Georg | Peptid-Varianten des Tumormarkers MUC1 und ihre Verwendung |
| GB9904695D0 (en) * | 1999-03-01 | 1999-04-21 | Imp Cancer Res Tech | Peptide |
| GB9930359D0 (en) * | 1999-12-22 | 2000-02-09 | Glaxo Group Ltd | Novel polypeptides |
| CA2322057A1 (en) * | 2000-05-18 | 2001-11-18 | Dnavec Research Inc. | Paramyxovirus vectors used for transfer of foreign genes |
| US20030232399A1 (en) * | 2000-06-14 | 2003-12-18 | Robertson John Forsyth Russell | Cancer detection methods and reagents |
| DK2266603T3 (da) | 2000-10-18 | 2012-11-05 | Glaxosmithkline Biolog Sa | Tumorvacciner |
| US20020142047A1 (en) * | 2001-01-19 | 2002-10-03 | Johnson Mark E. | Microsphere delivery of mucin peptides |
| CA2441809C (en) | 2001-03-27 | 2014-07-22 | Biomira, Inc. | Liposomal vaccines comprising dilipopeptides for modulating t1 and t2 immune responses |
| IL158184A0 (en) * | 2001-03-30 | 2004-03-28 | Univ California | Anti-muc-1 single chain antibodies for tumor targeting |
| US7183388B2 (en) * | 2001-03-30 | 2007-02-27 | The Regents Of The University Of California | Anti-MUC-1 single chain antibodies for tumor targeting |
| GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
| US7247297B2 (en) * | 2001-09-14 | 2007-07-24 | The University Of Chicago | Use of DF3/MUC1 regulated expression in gene therapy |
| WO2003033011A2 (en) * | 2001-10-18 | 2003-04-24 | Zlatko Ademovic | Repetitive motifs from salivary proline rich proteins, mucin and collagen |
| EP1465699A4 (de) * | 2001-12-12 | 2006-05-24 | Leon J Lewandowski | Photophoretische autoimmunstimulation |
| EP1585960A2 (de) * | 2002-01-14 | 2005-10-19 | Vertex Pharmaceuticals Incorporated | Mucinimmobiliserte chromatographie |
| JP2005526497A (ja) * | 2002-02-04 | 2005-09-08 | ビオミラ,インコーポレーテッド | 免疫刺激性、共有結合性脂質化オリゴヌクレオチド |
| CA2482477A1 (en) * | 2002-04-15 | 2003-10-30 | Biomira, Inc. | Synthetic glyco-lipo-peptides as vaccines |
| MXPA04010255A (es) | 2002-04-19 | 2008-03-04 | Univ Toronto | Metodos inmunologicos y composiciones para el tratamiento de la enfermedad de alzheimier. |
| GB0212036D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| US20060142546A1 (en) * | 2002-09-05 | 2006-06-29 | Franz-Georg Hanisch | Immunogenic muc1 glycopeptides |
| GB2395270B (en) * | 2002-11-14 | 2006-08-16 | Univ Nottingham | Tumour marker proteins and uses thereof |
| US8343502B2 (en) * | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
| KR101241272B1 (ko) * | 2002-12-16 | 2013-03-15 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 면역 요법으로서의 효모계 백신 |
| US7696306B2 (en) * | 2003-07-11 | 2010-04-13 | Board of Agents of the University of Nebraska | Compositions and methods for preventing or treating cancer |
| AU2004286144A1 (en) | 2003-11-04 | 2005-05-12 | Dnavec Research Inc. | Method for producing gene transferred dendritic cells |
| EP1687322B1 (de) * | 2003-11-12 | 2017-02-08 | The Government of the United States of America, represented by the Secretary, Department of Health and Human Services | Massgeschneiderte vektoren für die behandlung und prävention von bauchspeicheldrüsenkrebs |
| AU2004289340B2 (en) * | 2003-11-12 | 2010-11-11 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | System for treating and preventing breast cancer |
| DK1697399T3 (en) | 2003-12-12 | 2017-03-06 | Government Of The United States Of America As Repr By The Secr Of The Dept Of Health And Human Servi | Human cytotoxic t lymphocyte epitope and its agonist epitope from the non-variable number of muc-1 tandem repeat sequences |
| TW201204410A (en) * | 2004-04-01 | 2012-02-01 | Oncothyreon Inc | Mucinous glycoprotein (MUC-1) vaccine |
| US20100129385A1 (en) * | 2005-02-08 | 2010-05-27 | Jackson David C | Immunogenic molecules |
| GB2426581A (en) * | 2005-05-27 | 2006-11-29 | Univ Nottingham | Immunoassay methods |
| NZ563466A (en) | 2005-05-27 | 2009-12-24 | Oncimmune Ltd | Improved immunoassay methods |
| AU2006274651B2 (en) * | 2005-06-28 | 2012-09-27 | Oncothyreon Inc. | Method of treating patients with a mucinous glycoprotein (MUC-1) vaccine |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| CA2637600A1 (en) | 2006-01-17 | 2007-07-26 | Health Research, Inc. | Heteroduplex tracking assay |
| KR20080094910A (ko) | 2006-01-17 | 2008-10-27 | 디나벡크 가부시키가이샤 | 신규 단백질 발현계 |
| KR20090052857A (ko) | 2006-07-13 | 2009-05-26 | 디나벡크 가부시키가이샤 | 비복제형 파라믹소바이러스과 바이러스 벡터 |
| US20090317414A1 (en) * | 2006-07-25 | 2009-12-24 | 4G Vaccines Pty Ltd | Cancer vaccine comprising a mucin 1 (muc1) t cell epitope-derived peptide |
| CN101632020B (zh) | 2006-09-13 | 2013-11-27 | 昂西免疫有限公司 | 改进的免疫测定方法 |
| WO2008127680A2 (en) * | 2007-04-11 | 2008-10-23 | The Jackson Laboratory | Diagnosis and treatment of diseases caused by misfolded proteins |
| US20090124557A1 (en) * | 2007-04-16 | 2009-05-14 | Yeda Research And Development Co. Ltd. | Compositions and methods for treating cancer |
| CA2687632C (en) | 2007-05-24 | 2013-01-15 | Glaxosmithkline Biologicals S.A. | Lyophilised antigen composition |
| GB0725239D0 (en) * | 2007-12-24 | 2008-02-06 | Oncimmune Ltd | Calibrator for autoantibody assay |
| EP2351599A4 (de) | 2008-11-14 | 2013-05-08 | Dnavec Corp | Verfahren zur herstellung dendritischer zellen |
| WO2011140595A2 (en) | 2010-05-10 | 2011-11-17 | 4G Vaccines Pty Ltd | Immunostimulatory and vaccine compositions |
| CA2825972A1 (en) | 2011-02-24 | 2012-08-30 | Oncothyreon Inc. | Muc1 based glycolipopeptide vaccine with adjuvant |
| JP6523685B2 (ja) | 2012-01-03 | 2019-06-05 | アメリカ合衆国 | Muc1腫瘍抗原のネイティブ及びアゴニストctlエピトープ |
| WO2016105536A2 (en) * | 2014-12-23 | 2016-06-30 | University Of Maryland, Baltimore | Muc1 decoy peptides for treatment and prevention of bacterial infections |
| WO2018060368A2 (en) | 2016-09-28 | 2018-04-05 | Bavarian Nordic A/S | Compositions and methods for enhancing the stability of transgenes in poxviruses |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02273195A (ja) * | 1988-11-17 | 1990-11-07 | Univ Melbourne | ヒト多型性上皮ムチンと反応するモノクローナル抗体 |
| WO1991008217A1 (en) * | 1989-12-05 | 1991-06-13 | The Regents Of The University Of California | Human intestinal mucins |
-
1993
- 1993-07-30 US US08/099,354 patent/US5744144A/en not_active Expired - Lifetime
-
1994
- 1994-07-29 DE DE69432109T patent/DE69432109T2/de not_active Expired - Fee Related
- 1994-07-29 AT AT94925121T patent/ATE232109T1/de not_active IP Right Cessation
- 1994-07-29 CA CA002167730A patent/CA2167730A1/en not_active Abandoned
- 1994-07-29 EP EP94925121A patent/EP0804231B1/de not_active Expired - Lifetime
- 1994-07-29 JP JP7505945A patent/JPH09501159A/ja active Pending
- 1994-07-29 WO PCT/US1994/008477 patent/WO1995003825A1/en not_active Ceased
- 1994-08-10 US US08/288,059 patent/US5827666A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0804231A1 (de) | 1997-11-05 |
| JPH09501159A (ja) | 1997-02-04 |
| EP0804231A4 (de) | 1999-08-18 |
| WO1995003825A1 (en) | 1995-02-09 |
| US5827666A (en) | 1998-10-27 |
| EP0804231B1 (de) | 2003-02-05 |
| DE69432109D1 (de) | 2003-03-13 |
| CA2167730A1 (en) | 1995-02-09 |
| US5744144A (en) | 1998-04-28 |
| DE69432109T2 (de) | 2003-11-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE232109T1 (de) | Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendung | |
| DE69739035D1 (de) | Zusammensetzungen und Methoden zur Behandlung von Infektionen unter Verwendung von Indolicidinanalogen | |
| IL124831A0 (en) | Ob protein derivatives having prolonged half-life | |
| MX9305729A (es) | Formulas de proteinas de liberacion sostenida. | |
| ATE518874T1 (de) | Synthetische lipid-a analogen und verwendungen davon | |
| DE69934967D1 (de) | Verfahren zur verminderung der immunogenität von proteinen | |
| DE69731373D1 (de) | Cc-chemokinzeptor c-c ckr-5, dessen derivate und verwendungen | |
| RU94042922A (ru) | Новые соединения, способы их получения, фармацевтическая композиция | |
| CA2113995A1 (en) | Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins | |
| IT1178235B (it) | Composizioni farmaceutiche contenenti sucralfat e procedimento per la loro stabilizzazione | |
| FI953442A0 (fi) | Gonadotropiinia sisältäviä pakastekuivattuja pallosia | |
| FI20075338A7 (fi) | gp350/220:n ei silmukoivia muutoksia | |
| MY115211A (en) | Novel amino acid derivatives, their preparation and use | |
| DE69219590D1 (de) | BPC-Peptide, deren Herstellung und Verwendung | |
| BG104267A (en) | Aminoterminally incised rantes as haemokin antagonists | |
| DE69900756D1 (de) | Verwendung von hmg proteinen zur herstellung von arzneimitteln mit zytotoxischer wirkung | |
| DE3568048D1 (en) | Process for the synthesis of peptides | |
| BG103872A (en) | Glycoconjugates of 20(s)-camptotecin | |
| CA2201944A1 (en) | Analogs of keratinocyte growth factor having enhanced temperature stability | |
| SE9602822D0 (sv) | New receptor | |
| DE69529750D1 (de) | Verbesserungen in der herstellung von proteinen in wirtszellen | |
| DE59410221D1 (de) | Rekombinante chladosporium herbarum allergene | |
| UA42797C2 (uk) | Похідні хінолон- і нафтиридонкарбонової кислоти та похідні ізоіндолу для їх одержання | |
| DE68905097D1 (de) | Peptid-molekuele, wirksam gegen gram-positive keime. | |
| IL71870A0 (en) | Improved steroid ester preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |