ATE232384T1 - Zusammensetzungen zur behandlung von nikotinabhängigkeit, enthaltend mecamylamin und bupropion - Google Patents

Zusammensetzungen zur behandlung von nikotinabhängigkeit, enthaltend mecamylamin und bupropion

Info

Publication number
ATE232384T1
ATE232384T1 AT98949758T AT98949758T ATE232384T1 AT E232384 T1 ATE232384 T1 AT E232384T1 AT 98949758 T AT98949758 T AT 98949758T AT 98949758 T AT98949758 T AT 98949758T AT E232384 T1 ATE232384 T1 AT E232384T1
Authority
AT
Austria
Prior art keywords
compositions
bupropion
addiction
nicotine
mecamylamin
Prior art date
Application number
AT98949758T
Other languages
English (en)
Inventor
Douglas D Cary
Original Assignee
Cary Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cary Medical Corp filed Critical Cary Medical Corp
Application granted granted Critical
Publication of ATE232384T1 publication Critical patent/ATE232384T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT98949758T 1997-10-03 1998-10-02 Zusammensetzungen zur behandlung von nikotinabhängigkeit, enthaltend mecamylamin und bupropion ATE232384T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6079497P 1997-10-03 1997-10-03
PCT/US1998/020894 WO1999017803A1 (en) 1997-10-03 1998-10-02 Compositon for the treatment of nicotine addiction containing a nicotine receptor antagonist and an anti-depressant or anti-anxiety drug

Publications (1)

Publication Number Publication Date
ATE232384T1 true ATE232384T1 (de) 2003-02-15

Family

ID=22031798

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98949758T ATE232384T1 (de) 1997-10-03 1998-10-02 Zusammensetzungen zur behandlung von nikotinabhängigkeit, enthaltend mecamylamin und bupropion

Country Status (11)

Country Link
US (3) US6197827B1 (de)
EP (1) EP1019088B1 (de)
JP (1) JP2001518520A (de)
KR (1) KR20010030860A (de)
CN (1) CN1155410C (de)
AT (1) ATE232384T1 (de)
AU (1) AU750808B2 (de)
BR (1) BR9812615A (de)
CA (1) CA2305799C (de)
DE (1) DE69811378T2 (de)
WO (1) WO1999017803A1 (de)

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US6734215B2 (en) * 1998-12-16 2004-05-11 University Of South Florida Exo-S-mecamylamine formulation and use in treatment
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US6780871B2 (en) 2001-01-29 2004-08-24 Albany Medical College Methods and compositions for treating addiction disorders
EP1406518A4 (de) * 2001-06-08 2006-03-29 Vector Tobacco Ltd Modifikation von nicotin- und nitrosaminkonzentrationen in tabak
EP1418862A4 (de) * 2001-06-29 2010-06-09 Leon J Lewandowski Individualisierte suchttherapie
US20060105023A1 (en) * 2001-12-10 2006-05-18 Knight Joseph R Treatment of neurological disorders with nicotine
EP1461037B1 (de) * 2001-12-10 2007-08-01 Joseph Robert Knight Verfahren zur herstellung eines mit einer nikotin enthaltenden substanz behandelten getränks
WO2003086076A1 (en) * 2002-04-09 2003-10-23 Vector Tobacco Ltd. Tobacco having reduced nicotine and nitrosamines
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US20050215552A1 (en) * 2002-05-17 2005-09-29 Gadde Kishore M Method for treating obesity
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US6893660B2 (en) * 2002-11-21 2005-05-17 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions without a stabilizer
US20040115244A1 (en) * 2002-12-17 2004-06-17 Holgate Eric Jamison Methods and compositions for nicotine replacement therapy
WO2004080446A1 (en) * 2003-03-14 2004-09-23 Agi Therapeutics Ltd. Treatment of intestinal conditions with n-2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine
US20070224284A1 (en) 2004-03-12 2007-09-27 John Devane Methods and compositions comprising at least one alpha3 beta4 nAChR antagonist or pharmaceutically acceptable salt thereof
DE10318714B4 (de) * 2003-04-25 2006-03-23 Hf Arzneimittelforschung Gmbh Wirkstoff-Kombinationen und Therapien zur Bekämpfung des Alkoholmissbrauches
WO2004096201A1 (en) * 2003-04-29 2004-11-11 Orexigen Therapeutics, Inc. Compositions for affecting weight loss
KR101087464B1 (ko) * 2003-08-08 2011-11-25 밸리언트 인터내셔널(바베이도스) 에스알엘 부프로피온 히드로클로라이드의 개질 방출형 정제
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US20050096311A1 (en) * 2003-10-30 2005-05-05 Cns Response Compositions and methods for treatment of nervous system disorders
WO2005067909A1 (en) * 2004-01-06 2005-07-28 Yale University Combination therapy with mecamylamine for the treatment of mood disorders
US7713959B2 (en) * 2004-01-13 2010-05-11 Duke University Compositions of an anticonvulsant and mirtazapine to prevent weight gain
EP1734955A2 (de) * 2004-01-13 2006-12-27 Duke University Zusammensetzungen eines antikonvulsiven mittels und eines antipsychotischen mittels zur beeinflussung des gewichtsverlustes
US20050226920A1 (en) * 2004-04-13 2005-10-13 Kirk Voelker Method of decreasing nicotine withdrawal symptoms during smoking cessation.
EP1748776A1 (de) * 2004-05-03 2007-02-07 Duke University Zusammensetzungen zur beeinflussung des gewichtsverlusts
GB0501655D0 (en) * 2005-01-26 2005-03-02 Veritron Ltd Therapeutic use
CN100379422C (zh) * 2005-03-24 2008-04-09 重庆医药工业研究院有限责任公司 一种丙帕他莫与丁螺环酮的组合物
RU2408368C2 (ru) 2005-06-27 2011-01-10 Биовэйл Лэборэториз Интернэшнл С.Р.Л. Препараты соли бупропиона с модифицированным высвобождением
US7879913B2 (en) * 2005-06-28 2011-02-01 Catholic Healthcare West Iptakalim hydrochloride for decreasing nicotine use
ES2761812T3 (es) * 2005-11-22 2020-05-21 Nalpropion Pharmaceuticals Inc Composición y métodos de aumento de la sensibilidad a la insulina
WO2007089318A2 (en) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
US20080044462A1 (en) * 2006-04-06 2008-02-21 Collegium Pharmaceutical, Inc. Delaware Stabilized transdermal bupropion preparations
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
WO2008038155A2 (en) * 2006-07-25 2008-04-03 Intelgenx Corp. Controlled-release pharmaceutical tablets
US7674479B2 (en) * 2006-07-25 2010-03-09 Intelgenx Corp. Sustained-release bupropion and bupropion/mecamylamine tablets
US8703191B2 (en) * 2006-07-25 2014-04-22 Intelgenx Corp. Controlled-release pharmaceutical tablets
CL2007002903A1 (es) * 2006-10-09 2008-04-18 Smithkline Beecham Corp Composicion que comprende a) al menos un antagonista del receptor nicotinico a3beta4; y b) al menos un metabolito de la nicotina; y uso para reducir los sintomas de abstinencia de nicotina y/o el uso del tabaco.
DK2089005T3 (da) 2006-11-09 2010-07-19 Orexigen Therapeutics Inc Lagdelte farmaceutiske formuleringer omfattende et hurtigt opløsende mellemlag
KR20150082689A (ko) 2006-11-09 2015-07-15 오렉시젠 세러퓨틱스 인크. 단위 용량 팩키지
JP5647519B2 (ja) 2007-09-13 2014-12-24 コンサート ファーマシューティカルズ インコーポレイテッド 重水素化カテコールおよびベンゾ［ｄ］［１，３］ジオキソールおよびその誘導体の合成
DE102008015101A1 (de) 2008-03-19 2009-09-24 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Kauzusammensetzung und deren Verwendung
WO2009158114A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
CN102724878A (zh) * 2010-01-11 2012-10-10 奥雷西根治疗公司 在重度抑郁症患者中提供体重减轻疗法的方法
HUE072188T2 (hu) 2012-06-06 2025-10-28 Nalpropion Pharmaceuticals Llc Készítmény magas kardiovaszkuláris kockázatú túlsúlyos és elhízott páciensek kezelésére szolgáló eljárásban történõ alkalmazásra
US8969371B1 (en) 2013-12-06 2015-03-03 Orexigen Therapeutics, Inc. Compositions and methods for weight loss in at risk patient populations
CN107982517B (zh) * 2017-12-15 2020-03-06 苏州科技城医院 治疗心肌缺血型慢性心力衰竭的西药复方组合物
CN112569237B (zh) * 2019-09-30 2022-12-02 武汉大学 伊马替尼及其衍生物与尼古丁或其类似物联用或复方在防治尼古丁成瘾与复吸中的应用
JP2024517335A (ja) * 2021-05-11 2024-04-19 ローズ リサーチ センター，エルエルシー 組合せ治療方法
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

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ATE232384T1 (de) * 1997-10-03 2003-02-15 Cary Medical Corp Zusammensetzungen zur behandlung von nikotinabhängigkeit, enthaltend mecamylamin und bupropion

Also Published As

Publication number Publication date
CN1155410C (zh) 2004-06-30
EP1019088A1 (de) 2000-07-19
DE69811378T2 (de) 2004-02-12
AU750808B2 (en) 2002-07-25
US20010014678A1 (en) 2001-08-16
WO1999017803A1 (en) 1999-04-15
AU9601198A (en) 1999-04-27
CA2305799A1 (en) 1999-04-15
DE69811378D1 (de) 2003-03-20
BR9812615A (pt) 2000-08-01
EP1019088B1 (de) 2003-02-12
HK1034662A1 (en) 2001-11-02
CA2305799C (en) 2008-12-23
US20040044005A1 (en) 2004-03-04
JP2001518520A (ja) 2001-10-16
KR20010030860A (ko) 2001-04-16
US6197827B1 (en) 2001-03-06
CN1280505A (zh) 2001-01-17

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