ATE232866T1 - Neue triazolo(4,5d) pyrimidinverbindungen - Google Patents

Neue triazolo(4,5d) pyrimidinverbindungen

Info

Publication number
ATE232866T1
ATE232866T1 AT99906644T AT99906644T ATE232866T1 AT E232866 T1 ATE232866 T1 AT E232866T1 AT 99906644 T AT99906644 T AT 99906644T AT 99906644 T AT99906644 T AT 99906644T AT E232866 T1 ATE232866 T1 AT E232866T1
Authority
AT
Austria
Prior art keywords
pyrimidine compounds
new triazolo
triazolo
new
pyrimidine
Prior art date
Application number
AT99906644T
Other languages
English (en)
Inventor
Roger Brown
Garry Pairaudeau
Brian Springthorpe
Stephen Thom
Paul Willis
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9800458A external-priority patent/SE9800458D0/xx
Priority claimed from SE9803669A external-priority patent/SE9803669D0/xx
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Application granted granted Critical
Publication of ATE232866T1 publication Critical patent/ATE232866T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT99906644T 1998-02-17 1999-02-05 Neue triazolo(4,5d) pyrimidinverbindungen ATE232866T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9800458A SE9800458D0 (sv) 1998-02-17 1998-02-17 Novel compounds
SE9803669A SE9803669D0 (sv) 1998-10-26 1998-10-26 Novel compounds
PCT/SE1999/000154 WO1999041254A1 (en) 1998-02-17 1999-02-05 NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS

Publications (1)

Publication Number Publication Date
ATE232866T1 true ATE232866T1 (de) 2003-03-15

Family

ID=26663214

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99906644T ATE232866T1 (de) 1998-02-17 1999-02-05 Neue triazolo(4,5d) pyrimidinverbindungen

Country Status (21)

Country Link
US (1) US6369064B1 (de)
EP (1) EP1056749B1 (de)
JP (1) JP2002503663A (de)
KR (1) KR20010078696A (de)
CN (1) CN1291193A (de)
AR (1) AR015515A1 (de)
AT (1) ATE232866T1 (de)
AU (1) AU2650099A (de)
BR (1) BR9907934A (de)
CA (1) CA2316264A1 (de)
DE (1) DE69905451T2 (de)
HU (1) HUP0100328A3 (de)
ID (1) ID27127A (de)
IL (1) IL137812A0 (de)
MX (1) MXPA00007634A (de)
NO (1) NO20004089L (de)
NZ (1) NZ505250A (de)
PL (1) PL342430A1 (de)
SK (1) SK12242000A3 (de)
TR (1) TR200002380T2 (de)
WO (1) WO1999041254A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702773D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9904129D0 (sv) * 1999-11-15 1999-11-15 Astra Pharma Prod Novel compounds
AR028110A1 (es) * 2000-06-02 2003-04-23 Astrazeneca Ab Nuevo proceso
GB0013488D0 (en) * 2000-06-02 2000-07-26 Astrazeneca Ab Chemical compound
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
GB0219746D0 (en) 2002-08-23 2002-10-02 Inst Of Ex Botany Ascr Azapurine derivatives
US7504497B2 (en) 2003-10-21 2009-03-17 Inspire Pharmaceuticals, Inc. Orally bioavailable compounds and methods for inhibiting platelet aggregation
WO2005040174A1 (en) * 2003-10-21 2005-05-06 Inspire Pharmaceuticals, Inc. Tetrahydro-furo`3,4-d!dioxole compounds and compositions and method for inhibiting platelet aggregation
US7749981B2 (en) * 2003-10-21 2010-07-06 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound
US7335648B2 (en) * 2003-10-21 2008-02-26 Inspire Pharmaceuticals, Inc. Non-nucleotide composition and method for inhibiting platelet aggregation
US7932376B2 (en) 2005-05-05 2011-04-26 Inspire Pharmaceuticals, Inc. Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation
JPWO2007020935A1 (ja) * 2005-08-17 2009-02-26 小野薬品工業株式会社 Ｐ２ｙ１２受容体および／またはｐ２ｙ１４受容体ブロッカーを含有してなる疼痛治療剤
US7566722B2 (en) * 2006-10-31 2009-07-28 Janssen Pharmaceutica, N.V. Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists
SI2340252T1 (sl) * 2008-09-09 2016-02-29 Astrazeneca Ab Postopek priprave (1S-)1-alfa, 2-alfa, 3-beta(1S*,2R*)5-beta))-3-(7-(2-(3,4-difluorofenil)-ciklopropilamino)-5- (propiltio)-3H-1,2,3-triazolo(4,5-D)pirimidin-3-il)-5-(2-hidroksietoksi) ciklopentan-1,2-diola in njegovih vmesnih spojin
WO2015027431A1 (en) * 2013-08-29 2015-03-05 Merck Sharp & Dohme Corp. 2,2-difluorodioxolo a2a receptor antagonists
WO2015162630A1 (en) * 2014-04-25 2015-10-29 Anlon Chemical Research Organization Novel processes for preparing triazolo [4,5-d]- pyrimidines, including ticagrelor, vianew intermediates and new route of synthesis.
GEAP202014908A (en) 2016-03-22 2020-03-10 Merck Sharp & Dohme Allosteric modulators of nicotinic acetylcholine receptors
CN111116592A (zh) * 2019-11-27 2020-05-08 杭州沧海帆医药科技有限公司 嘧啶并三氮唑类化合物及其医药用途
CN112876485A (zh) * 2021-01-25 2021-06-01 郭丽伟 一种用于治疗子宫平滑肌高频率强直性收缩相关疾病的化合物
EP4436566A4 (de) * 2021-11-22 2025-07-16 Purdue Research Foundation Zellpotente bisubstratinhibitoren für nikotinamid-n-methyltransferase (nnmt) und verwendungen davon

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742064A (en) 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
GB8826205D0 (en) 1988-11-09 1988-12-14 Wellcome Found Heterocyclic compounds
HU221880B1 (hu) 1995-07-11 2003-02-28 Astrazeneca Ab, Vérlemezke-aggregáció inhibitorok, ezeket tartalmazó gyógyszerkészítmények és előállításuk
ATE213245T1 (de) * 1996-12-20 2002-02-15 Triazolo(4,5-d)pyrimidinyl-derivate und ihre verwendung als medikamente
SE9702772D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
SE9702774D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds

Also Published As

Publication number Publication date
KR20010078696A (ko) 2001-08-21
CA2316264A1 (en) 1999-08-19
MXPA00007634A (es) 2003-09-10
HUP0100328A3 (en) 2003-04-28
DE69905451T2 (de) 2003-11-20
HUP0100328A2 (hu) 2001-09-28
ID27127A (id) 2001-03-01
WO1999041254A1 (en) 1999-08-19
CN1291193A (zh) 2001-04-11
BR9907934A (pt) 2000-10-24
US6369064B1 (en) 2002-04-09
JP2002503663A (ja) 2002-02-05
AU2650099A (en) 1999-08-30
IL137812A0 (en) 2001-10-31
AR015515A1 (es) 2001-05-02
NO20004089L (no) 2000-10-16
EP1056749B1 (de) 2003-02-19
NO20004089D0 (no) 2000-08-16
DE69905451D1 (de) 2003-03-27
NZ505250A (en) 2002-10-25
SK12242000A3 (sk) 2001-03-12
TR200002380T2 (tr) 2001-03-21
EP1056749A1 (de) 2000-12-06
PL342430A1 (en) 2001-06-04

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties