ATE232901T1 - Biologisch aktive ligande der eph familie - Google Patents

Biologisch aktive ligande der eph familie

Info

Publication number: ATE232901T1
Authority: AT; Austria
Prior art keywords: biologically active; eph family; active ligands; ligands; novel
Prior art date: 1994-04-04

Application number

AT95916204T

Other languages

English (en)

Inventor

Samuel Davis

Nicholas Gale

Thomas H Aldrich

Peter C Maisonpierre

Mitchell Goldfarb

George D Yancopoulos

Original Assignee

Regeneron Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-04

Filing date

1995-04-04

Publication date

2003-03-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27499262&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE232901(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1994-09-01 Priority claimed from US08/299,567 external-priority patent/US5747033A/en

1995-04-04 Application filed by Regeneron Pharma filed Critical Regeneron Pharma

2003-03-15 Application granted granted Critical

2003-03-15 Publication of ATE232901T1 publication Critical patent/ATE232901T1/de

Links

239000003446 ligand Substances 0.000 title abstract 3
102000050554 Eph Family Receptors Human genes 0.000 abstract 1
108091008815 Eph receptors Proteins 0.000 abstract 1
102000016979 Other receptors Human genes 0.000 abstract 1
102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
239000002299 complementary DNA Substances 0.000 abstract 1
230000001537 neural effect Effects 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

AT95916204T 1994-04-04 1995-04-04 Biologisch aktive ligande der eph familie ATE232901T1 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US22207594A	1994-04-04	1994-04-04
US22940294A	1994-04-12	1994-04-12
US08/299,567 US5747033A (en)	1993-10-28	1994-09-01	Method of enhancing the biological activity of Eph family ligands
US32742394A	1994-10-21	1994-10-21
PCT/US1995/004208 WO1995027060A2 (en)	1994-04-04	1995-04-04	Biologically active eph family ligands

Publications (1)

Publication Number	Publication Date
ATE232901T1 true ATE232901T1 (de)	2003-03-15

Family

ID=27499262

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95916204T ATE232901T1 (de)	1994-04-04	1995-04-04	Biologisch aktive ligande der eph familie

Country Status (9)

Country	Link
EP (1)	EP0758381B2 (de)
JP (1)	JP3686084B2 (de)
AT (1)	ATE232901T1 (de)
AU (1)	AU691915B2 (de)
CA (1)	CA2187167A1 (de)
DE (1)	DE69529674T3 (de)
ES (1)	ES2192199T5 (de)
IL (1)	IL113252A0 (de)
WO (1)	WO1995027060A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5824303A (en) *	1992-11-13	1998-10-20	Amgen Inc.	Eck receptor ligands
US5624899A (en) *	1994-07-20	1997-04-29	Genentech Inc.	Method for using Htk ligand
WO1996013518A1 (en) *	1994-10-27	1996-05-09	Genentech, Inc.	Al-1 neurotrophic factor, a ligand for an eph-related tyrosine kinase receptor
US5759775A (en)	1994-10-27	1998-06-02	Genetech, Inc.	Methods for detecting nucleic acids encoding AL--1 neurotrophic factor
JPH11515105A (ja) *	1995-10-13	1999-12-21	マウント・サイナイ・ホスピタル・コーポレイション	新規リガンド調節経路の活性化方法
US6610296B2 (en)	1995-10-26	2003-08-26	Genentech, Inc.	Methods of enhancing cognitive function using an AL-1 neurotrophic factor immunoadhesin
US6696557B1 (en) *	1996-04-19	2004-02-24	Genentech, Inc.	AL-2 neurotrophic factor nucleic acid
US6413730B1 (en)	1996-07-05	2002-07-02	Mount Sinai Hospital Corporation	Method for identifying compounds that inhibit or enhance activation of a transmembrane ligand for a receptor tyrosine kinase
US5994112A (en) *	1996-10-09	1999-11-30	Incyte Pharmaceuticals, Inc.	Human protein tyrosine kinase
AU1764200A (en) *	1998-12-18	2000-07-12	Mount Sinai Hospital Corporation	Three dimensional structure of a sterile alpha motif domain
WO2000037642A1 (en) *	1998-12-23	2000-06-29	Regeneron Pharmaceuticals, Inc.	Method of enhancing the biological activity of ligands
EP2789630A1 (de)	2013-04-09	2014-10-15	EngMab AG	Bispezifische Antikörper gegen CD3e und ROR1
CA2963692A1 (en)	2014-10-09	2016-04-14	Engmab Ag	Bispecific antibodies against cd3epsilon and ror1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5151360A (en) *	1990-12-31	1992-09-29	Biomembrane Institute	Effect of n,n,n-trimethylsphingosine on protein kinase-c activity, melanoma cell growth in vitro, metastatic potential in vivo and human platelet aggregation
PT669929E (pt) *	1992-11-13	2007-04-30	Immunex Corp	Ligando de elk, uma citoquina
AU685765B2 (en) *	1992-11-13	1998-01-29	Amgen, Inc.	(Eck) receptor ligands
US5516658A (en) *	1993-08-20	1996-05-14	Immunex Corporation	DNA encoding cytokines that bind the cell surface receptor hek

1995
- 1995-04-04 DE DE69529674T patent/DE69529674T3/de not_active Expired - Fee Related
- 1995-04-04 EP EP95916204A patent/EP0758381B2/de not_active Expired - Lifetime
- 1995-04-04 WO PCT/US1995/004208 patent/WO1995027060A2/en not_active Ceased
- 1995-04-04 AU AU22789/95A patent/AU691915B2/en not_active Ceased
- 1995-04-04 JP JP52594195A patent/JP3686084B2/ja not_active Expired - Fee Related
- 1995-04-04 IL IL11325295A patent/IL113252A0/xx not_active IP Right Cessation
- 1995-04-04 AT AT95916204T patent/ATE232901T1/de not_active IP Right Cessation
- 1995-04-04 CA CA002187167A patent/CA2187167A1/en not_active Abandoned
- 1995-04-04 ES ES95916204T patent/ES2192199T5/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP3686084B2 (ja)	2005-08-24
DE69529674T3 (de)	2007-06-28
WO1995027060A3 (en)	1995-11-02
AU691915B2 (en)	1998-05-28
ES2192199T5 (es)	2007-07-01
IL113252A0 (en)	1995-07-31
ES2192199T3 (es)	2003-10-01
DE69529674D1 (de)	2003-03-27
CA2187167A1 (en)	1995-10-12
AU2278995A (en)	1995-10-23
EP0758381A1 (de)	1997-02-19
DE69529674T2 (de)	2003-12-18
EP0758381B2 (de)	2006-11-15
JPH09511401A (ja)	1997-11-18
WO1995027060A2 (en)	1995-10-12
EP0758381B1 (de)	2003-02-19

Legal Events

Date	Code	Title	Description
2003-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69529674D1 (de)	2003-03-27	Biologisch aktive ligande der eph familie
CY1107821T1 (el)	2013-06-19	Πολυπεπτιδιο παραγοντα viii με ενεργοτητα παραγοντα viii:c
FI104180B1 (fi)	1999-11-30	Menetelmä polypeptidin vasta-aineen ekä IL-4 välittämien tilojen hoitoon tarkoitetun seoksen valmistamiseksi
DE69029799D1 (de)	1997-03-06	Modifizierte formen von fortpflanzungshormonen
IL100343A0 (en)	1992-09-06	G protein coupled glutamate receptors
NO965362L (no)	1997-02-13	Syntetiske lederpeptidsekvenser
ATE404583T1 (de)	2008-08-15	Funktionelle antagonisten von hedgehog-aktivität
DK1749888T3 (da)	2010-05-10	Opløselige Zalph11a-cytokinreceptorer
WO2002012345A3 (en)	2003-06-12	Soluble zcytor 11 cytokine receptors
EP0218531A3 (de)	1989-07-12	Immunogenische Peptide von menschlichem Interleukin-1 und die entsprechenden Antipeptid-Antikörper
ES8606494A1 (es)	1986-04-16	Un metodo de producir un peptido o polipeptido sintetico.
EP0515516A4 (en)	1993-03-31	Totally synthetic affinity reagents
DK0759942T3 (da)	2003-06-10	Interleukin-15-receptorer
PL349158A1 (en)	2002-07-01	Method of enhancing the biological activity of ligands
DE69712124D1 (de)	2002-05-29	Hormones de croissance humaines mutantes et leur utilisation
ATE359291T1 (de)	2007-05-15	Brustkrebsresistenzprotein (bcrp) und für dieses kodierende dna
ATE314470T1 (de)	2006-01-15	Biologisch aktive liganden der eph familie
IL127363A0 (en)	1999-10-28	IL-1/TNF-alpha-activated kinase and methods of making and using the same
DE59911530D1 (de)	2005-03-03	Zellpermeabilität-vermittelndes polypeptid
MXPA02011938A (es)	2004-09-06	Adn que codifica para un receptor de histamina de mamifero del subtipo h4.
CA2236001A1 (en)	1997-05-01	Biologically active eph family ligands
DE58909261D1 (de)	1995-06-29	Ancrod-proteine, ihre herstellung und verwendung.