ATE232901T1 - Biologisch aktive ligande der eph familie - Google Patents
Biologisch aktive ligande der eph familieInfo
- Publication number
- ATE232901T1 ATE232901T1 AT95916204T AT95916204T ATE232901T1 AT E232901 T1 ATE232901 T1 AT E232901T1 AT 95916204 T AT95916204 T AT 95916204T AT 95916204 T AT95916204 T AT 95916204T AT E232901 T1 ATE232901 T1 AT E232901T1
- Authority
- AT
- Austria
- Prior art keywords
- biologically active
- eph family
- active ligands
- ligands
- novel
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 3
- 102000050554 Eph Family Receptors Human genes 0.000 abstract 1
- 108091008815 Eph receptors Proteins 0.000 abstract 1
- 102000016979 Other receptors Human genes 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22207594A | 1994-04-04 | 1994-04-04 | |
| US22940294A | 1994-04-12 | 1994-04-12 | |
| US08/299,567 US5747033A (en) | 1993-10-28 | 1994-09-01 | Method of enhancing the biological activity of Eph family ligands |
| US32742394A | 1994-10-21 | 1994-10-21 | |
| PCT/US1995/004208 WO1995027060A2 (en) | 1994-04-04 | 1995-04-04 | Biologically active eph family ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE232901T1 true ATE232901T1 (de) | 2003-03-15 |
Family
ID=27499262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95916204T ATE232901T1 (de) | 1994-04-04 | 1995-04-04 | Biologisch aktive ligande der eph familie |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0758381B2 (de) |
| JP (1) | JP3686084B2 (de) |
| AT (1) | ATE232901T1 (de) |
| AU (1) | AU691915B2 (de) |
| CA (1) | CA2187167A1 (de) |
| DE (1) | DE69529674T3 (de) |
| ES (1) | ES2192199T5 (de) |
| IL (1) | IL113252A0 (de) |
| WO (1) | WO1995027060A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824303A (en) * | 1992-11-13 | 1998-10-20 | Amgen Inc. | Eck receptor ligands |
| US5864020A (en) * | 1994-07-20 | 1999-01-26 | Genentech, Inc. | HTK ligand |
| US5759775A (en) * | 1994-10-27 | 1998-06-02 | Genetech, Inc. | Methods for detecting nucleic acids encoding AL--1 neurotrophic factor |
| EP0787148B1 (de) * | 1994-10-27 | 2004-04-07 | Genentech, Inc. | Neurotrophischer al-1 faktor, einer ligand verwant mit dem eph tyrosine kinase receptor |
| EP1019728A1 (de) * | 1995-10-13 | 2000-07-19 | Mount Sinai Hospital | Verfahren zur aktivierung eines neuen ligand-regulierten wegs |
| US6610296B2 (en) | 1995-10-26 | 2003-08-26 | Genentech, Inc. | Methods of enhancing cognitive function using an AL-1 neurotrophic factor immunoadhesin |
| US6696557B1 (en) * | 1996-04-19 | 2004-02-24 | Genentech, Inc. | AL-2 neurotrophic factor nucleic acid |
| CA2259157A1 (en) | 1996-07-05 | 1998-01-15 | Mount Sinai Hospital Corporation | Oligomerized receptors which affect pathways regulated by transmembrane ligands for elk-related receptor tyrosine kinases |
| US5994112A (en) * | 1996-10-09 | 1999-11-30 | Incyte Pharmaceuticals, Inc. | Human protein tyrosine kinase |
| EP1141016A1 (de) * | 1998-12-18 | 2001-10-10 | Mount Sinai Hospital | Dreidimensionale struktur einer domäne vom typ des sterilen alpha motifs |
| IL143558A0 (en) * | 1998-12-23 | 2002-04-21 | Regeneron Pharma | Method of enhancing the biological activity of ligands |
| EP2789630A1 (de) | 2013-04-09 | 2014-10-15 | EngMab AG | Bispezifische Antikörper gegen CD3e und ROR1 |
| EP3204415B1 (de) | 2014-10-09 | 2020-06-17 | EngMab Sàrl | Bispezifische antikörper gegen cd3epsilon und ror1 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5151360A (en) * | 1990-12-31 | 1992-09-29 | Biomembrane Institute | Effect of n,n,n-trimethylsphingosine on protein kinase-c activity, melanoma cell growth in vitro, metastatic potential in vivo and human platelet aggregation |
| WO1994011384A1 (en) * | 1992-11-13 | 1994-05-26 | Immunex Corporation | Novel cytokine designated elk ligand |
| JPH08505765A (ja) * | 1992-11-13 | 1996-06-25 | アムジエン・インコーポレーテツド | Eck受容体リガンド |
| US5516658A (en) * | 1993-08-20 | 1996-05-14 | Immunex Corporation | DNA encoding cytokines that bind the cell surface receptor hek |
-
1995
- 1995-04-04 AT AT95916204T patent/ATE232901T1/de not_active IP Right Cessation
- 1995-04-04 ES ES95916204T patent/ES2192199T5/es not_active Expired - Lifetime
- 1995-04-04 AU AU22789/95A patent/AU691915B2/en not_active Ceased
- 1995-04-04 DE DE69529674T patent/DE69529674T3/de not_active Expired - Fee Related
- 1995-04-04 CA CA002187167A patent/CA2187167A1/en not_active Abandoned
- 1995-04-04 EP EP95916204A patent/EP0758381B2/de not_active Expired - Lifetime
- 1995-04-04 JP JP52594195A patent/JP3686084B2/ja not_active Expired - Fee Related
- 1995-04-04 IL IL11325295A patent/IL113252A0/xx not_active IP Right Cessation
- 1995-04-04 WO PCT/US1995/004208 patent/WO1995027060A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0758381B1 (de) | 2003-02-19 |
| CA2187167A1 (en) | 1995-10-12 |
| WO1995027060A2 (en) | 1995-10-12 |
| JP3686084B2 (ja) | 2005-08-24 |
| EP0758381A1 (de) | 1997-02-19 |
| JPH09511401A (ja) | 1997-11-18 |
| AU691915B2 (en) | 1998-05-28 |
| ES2192199T3 (es) | 2003-10-01 |
| EP0758381B2 (de) | 2006-11-15 |
| ES2192199T5 (es) | 2007-07-01 |
| IL113252A0 (en) | 1995-07-31 |
| AU2278995A (en) | 1995-10-23 |
| DE69529674T3 (de) | 2007-06-28 |
| DE69529674D1 (de) | 2003-03-27 |
| WO1995027060A3 (en) | 1995-11-02 |
| DE69529674T2 (de) | 2003-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |