ATE233084T1 - Pharmazeutische aerosolformulierung - Google Patents

Pharmazeutische aerosolformulierung

Info

Publication number: ATE233084T1
Authority: AT; Austria
Prior art keywords: pharmaceutical aerosol; formulations; aerosol formulation; relates; novel
Prior art date: 1999-04-14

Application number

AT00925450T

Other languages

English (en)

Inventor

Cecile Isabelle Bonvoisin

Christophe Laroche

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-14

Filing date

2000-04-13

Publication date

2003-03-15

1999-09-10 Priority claimed from GBGB9921289.6A external-priority patent/GB9921289D0/en

2000-04-13 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2003-03-15 Application granted granted Critical

2003-03-15 Publication of ATE233084T1 publication Critical patent/ATE233084T1/de

Links

239000000203 mixture Substances 0.000 title abstract 5
238000009472 formulation Methods 0.000 title abstract 4
239000008249 pharmaceutical aerosol Substances 0.000 title abstract 2
239000002245 particle Substances 0.000 abstract 2
YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 abstract 1
LVGUZGTVOIAKKC-UHFFFAOYSA-N 1,1,1,2-tetrafluoroethane Chemical compound FCC(F)(F)F LVGUZGTVOIAKKC-UHFFFAOYSA-N 0.000 abstract 1
GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 abstract 1
239000011248 coating agent Substances 0.000 abstract 1
238000000576 coating method Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
239000003380 propellant Substances 0.000 abstract 1
230000002685 pulmonary effect Effects 0.000 abstract 1
229960005018 salmeterol xinafoate Drugs 0.000 abstract 1
238000001694 spray drying Methods 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Emergency Medicine (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT00925450T 1999-04-14 2000-04-13 Pharmazeutische aerosolformulierung ATE233084T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
BH12699		1999-04-14
GBGB9921289.6A GB9921289D0 (en)	1999-09-10	1999-09-10	Pharmaceutical aerosol formulation
PCT/GB2000/001418 WO2000061108A1 (en)	1999-04-14	2000-04-13	Pharmaceutical aerosol formulation

Publications (1)

Publication Number	Publication Date
ATE233084T1 true ATE233084T1 (de)	2003-03-15

Family

ID=25663377

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00925450T ATE233084T1 (de)	1999-04-14	2000-04-13	Pharmazeutische aerosolformulierung

Country Status (10)

Country	Link
US (1)	US7090831B1 (de)
EP (1)	EP1169019B1 (de)
JP (1)	JP2002541183A (de)
AT (1)	ATE233084T1 (de)
AU (1)	AU4417500A (de)
DE (1)	DE60001492T2 (de)
DK (1)	DK1169019T3 (de)
ES (1)	ES2193069T3 (de)
PT (1)	PT1169019E (de)
WO (1)	WO2000061108A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080064613A1 (en) *	2006-09-11	2008-03-13	M-I Llc	Dispersant coated weighting agents
EP1337239B2 (de)	2000-11-30	2015-11-25	Vectura Limited	Partikel zur verwendung in einer pharmazeutischen zusammensetzung
ES2587135T3 (es)	2000-11-30	2016-10-20	Vectura Limited	Procedimiento de fabricación de partículas para su uso en una composición farmacéutica
KR100881258B1 (ko) *	2000-12-22	2009-02-05	글락소 그룹 리미티드	살메테롤 지나포에이트를 위한 정량식 흡입기
CA2459493C (en) *	2001-09-14	2011-08-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New pharmaceutical compositions for inhalation
AU2003259910A1 (en) *	2002-08-14	2004-03-03	E.I. Du Pont De Nemours And Company	Process for coating a pharmaceutical particle
PE20040950A1 (es)	2003-02-14	2005-01-01	Theravance Inc	DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
EP1628641A2 (de) *	2003-05-19	2006-03-01	Baxter International Inc.	Feste partikel, die ein antikonvulsivum oder ein immunsuppressivum enthalten und die mit einer oder mehreren oberflächen-modifizierenden substanzen beschichtet sind
GB0321607D0 (en) †	2003-09-15	2003-10-15	Vectura Ltd	Manufacture of pharmaceutical compositions
EP1688169A4 (de) *	2003-11-28	2008-10-01	Mitsubishi Chem Corp	Verfahren zur herstellung von feinen teilchen einer organischen verbindung
TWI341836B (en)	2004-03-11	2011-05-11	Theravance Inc	Biphenyl compounds useful as muscarinic receptor antagonists
EP1833822A2 (de)	2004-08-16	2007-09-19	Theravance, Inc.	Verbindungen mit beta2 adrenerg-rezeptor agonistischer und muscarin-rezeptor antagonistischer aktivität
WO2009069619A1 (ja) *	2007-11-27	2009-06-04	Erc Technology Inc.	オゾン化界面活性剤を含有する新規組成物
EP3620154A1 (de)	2009-02-06	2020-03-11	University Of Southern California	Therapeutische zusammensetzungen mit monoterpenen
SI3106149T1 (sl)	2009-05-29	2020-07-31	Pearl Therapeutics, Inc.	Sestavki za pljučno dostavo muskarinskih antagonistov z dolgotrajnim delovanjem in agonistov beta-2 adrenergičnega receptorja z dolgotrajnim delovanjem in povezani postopki in sistemi
US8815258B2 (en)	2009-05-29	2014-08-26	Pearl Therapeutics, Inc.	Compositions, methods and systems for respiratory delivery of two or more active agents
HUE026414T2 (hu)	2009-07-15	2016-05-30	Theravance Biopharma R&D Ip Llc	Bifenil-vegyület kristályos szabad-bázis formája
BR112012022209A2 (pt)	2010-03-03	2017-06-06	Neonc Tech Inc	composições farmacêuticas compreendendo monoterpenos
US20160038600A1 (en)	2012-08-03	2016-02-11	Neonc Technologies Inc.	Pharmaceutical compositions comprising poh derivatives
CN105078973B (zh)	2010-08-27	2020-10-09	尼昂克技术公司	包含poh衍生物的药物组合物
CN105616391B (zh)	2010-12-17	2021-03-19	尼昂克技术公司	使用异紫苏醇的方法和装置
ES2704465T3 (es)	2011-10-11	2019-03-18	Chiesi Farm Spa	Micropartículas cristalinas de un agonista de beta recubierto con un ácido graso
US9700558B2 (en)	2013-03-15	2017-07-11	Verona Pharma Plc	Drug combination of PDE3/PDE4 inhibitor and muscarinic receptor antagonist
HK1219059A1 (zh)	2013-03-15	2017-03-24	珍珠治疗公司	用於微粒晶体材料的状态调节的方法和系统
DE102013021718B4 (de) *	2013-12-20	2017-03-02	Gerresheimer Regensburg Gmbh	Kapsel zur Verwendung als Reservoir für eine pharmazeutische, vorzugsweise pulverförmige Zubereitung in einem Inhalator sowie Inhalator dafür
SI3142701T1 (en)	2014-05-12	2018-08-31	Verona Pharma Plc	NEW TREATMENT
EP3872069A1 (de)	2015-02-12	2021-09-01	Neonc Technologies, Inc.	Pharmazeutische zusammensetzungen mit perillylalkoholderivaten
DK3547836T3 (da)	2016-11-30	2024-11-18	Univ Southern California	Perillylalkohol-3 brompyruvat-konjugat og fremgangsmåder til behandling af cancer
CN119868317A (zh)	2018-02-08	2025-04-25	南加州大学	穿透血脑屏障的方法
WO2021216710A1 (en)	2020-04-24	2021-10-28	The Medical College Of Wisconsin, Inc.	Use of salmeterol as an anti-coronaviral agent

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1535531A (en) *	1976-10-15	1978-12-13	Warmer & Co Ltd W	Pharmaceutical compositions
ZW6584A1 (en)	1983-04-18	1985-04-17	Glaxo Group Ltd	Phenethanolamine derivatives
WO1988001165A1 (en)	1986-08-11	1988-02-25	Innovata Biomed Limited	Pharmaceutical formulations comprising microcapsules
GB8921222D0 (en)	1989-09-20	1989-11-08	Riker Laboratories Inc	Medicinal aerosol formulations
AU7908791A (en)	1990-05-08	1991-11-27	Liposome Technology, Inc.	Direct spray-dried drug/lipid powder composition
GB9024366D0 (en)	1990-11-09	1991-01-02	Glaxo Group Ltd	Medicaments
GB9024365D0 (en) *	1990-11-09	1991-01-02	Glaxo Group Ltd	Medicaments
GB9026005D0 (en)	1990-11-29	1991-01-16	Glaxo Group Ltd	Drug material suitable for micronisation
IL104068A (en)	1991-12-12	1998-10-30	Glaxo Group Ltd	Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
DE69227257T2 (de)	1991-12-12	1999-03-25	Glaxo Group Ltd	Arzneimittel
ES2089357T3 (es)	1991-12-31	1996-10-01	Hoechst Ag	Formulacion medicinal en forma de aerosol.
MX9304585A (es)	1992-07-31	1994-03-31	Glaxo Group Ltd	Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
EP0655237A1 (de) *	1993-11-27	1995-05-31	Hoechst Aktiengesellschaft	Medizinische Aerosolformulierung
GB9419536D0 (en) *	1994-09-28	1994-11-16	Glaxo Inc	Medicaments
JPH08151322A (ja) *	1994-09-30	1996-06-11	Takeda Chem Ind Ltd	経口徐放剤
GB9425160D0 (en) *	1994-12-10	1995-02-08	Glaxo Group Ltd	Medicaments
GB9606188D0 (en)	1996-03-23	1996-05-29	Danbiosyst Uk	Pollysaccharide microspheres for the pulmonary delivery of drugs
JP2001507701A (ja)	1996-12-31	2001-06-12	インヘイル・セラピューティック・システムズ・インコーポレーテッド	親水性賦形剤を有する疎水性薬剤の溶液を噴霧乾燥するための方法及びその方法によって作製された組成物
JP2002512183A (ja) *	1998-04-18	2002-04-23	グラクソグループリミテッド	医薬用エアゾール製剤
GB9828721D0 (en)	1998-12-24	1999-02-17	Glaxo Group Ltd	Novel apparatus and process

2000
- 2000-04-13 ES ES00925450T patent/ES2193069T3/es not_active Expired - Lifetime
- 2000-04-13 US US09/958,788 patent/US7090831B1/en not_active Expired - Fee Related
- 2000-04-13 AU AU44175/00A patent/AU4417500A/en not_active Abandoned
- 2000-04-13 PT PT00925450T patent/PT1169019E/pt unknown
- 2000-04-13 DK DK00925450T patent/DK1169019T3/da active
- 2000-04-13 EP EP00925450A patent/EP1169019B1/de not_active Expired - Lifetime
- 2000-04-13 AT AT00925450T patent/ATE233084T1/de not_active IP Right Cessation
- 2000-04-13 WO PCT/GB2000/001418 patent/WO2000061108A1/en not_active Ceased
- 2000-04-13 JP JP2000610441A patent/JP2002541183A/ja active Pending
- 2000-04-13 DE DE60001492T patent/DE60001492T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PT1169019E (pt)	2003-07-31
DE60001492D1 (de)	2003-04-03
ES2193069T3 (es)	2003-11-01
DE60001492T2 (de)	2003-12-18
AU4417500A (en)	2000-11-14
US7090831B1 (en)	2006-08-15
WO2000061108A1 (en)	2000-10-19
EP1169019A1 (de)	2002-01-09
DK1169019T3 (da)	2003-06-02
JP2002541183A (ja)	2002-12-03
EP1169019B1 (de)	2003-02-26

Legal Events

Date

Code

Title

Description

2003-08-15

UEP

Publication of translation of european patent specification

Ref document number: 1169019

Country of ref document: EP

2010-01-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE60001492D1 (de)	2003-04-03	Pharmazeutische aerosolformulierung
AP2000001961A0 (en)	2000-12-31	Pharmaceutical aerosol formulation.
DE60123793D1 (de)	2006-11-23	Neue aerosolformulierungen ein polares fluoriniertes molekül enthaltend
ES2178817T3 (es)	2003-01-01	Formulaciones medicinales de aerosol.
IT1255040B (it)	1995-10-13	Forma di ciclosporina adatta alla somministrazione per via polmonare eprocedimento di preparazione.
NZ240237A (en)	1994-06-27	An aerosol formulation (free of surfactant) for treatment of asthma comprising: a hydrofluorocarbon propellant, ethanol, and beclomethasone 17,21 dipropionate; preparation thereof
NO20010391L (no)	2001-03-23	Medisinske aerosolformuleringer
ATE216575T1 (de)	2002-05-15	Treibgasmischung für eine aerosolzubereitung
ATE291898T1 (de)	2005-04-15	Pharmazeutische aerosol formulierung enthaltend salmeterol und fluticason
ATE398999T1 (de)	2008-07-15	Aerosol-formulierungen von formoterol und mometason
HUP0002691A2 (hu)	2001-02-28	Ciklezonid tartalmú gyógyászati aeroszol termékek
CA2441549A1 (en)	2002-10-31	Ipratropium formulation for pulmonary inhalation
WO1999024016A8 (en)	1999-07-29	Emulsions for aerosolization and drug delivery
AU1534501A (en)	2001-06-04	Pharmaceutical formulations of salmeterol
BR0303347A (pt)	2004-07-13	Formulações de aerossol contendo ésteres de derivados de 3,17-diidroxi estratieno para deposição pulmonar
TH29519B (th)	1998-08-14	สูตรผสมทางเภสัชศาสตร์ที่เสถียรชนิดใหม่สำหรับการผลิตละอองลอยที่ไม่มีแก๊สผลักดัน