ATE233089T1 - Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen - Google Patents

Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen

Info

Publication number
ATE233089T1
ATE233089T1 AT99960118T AT99960118T ATE233089T1 AT E233089 T1 ATE233089 T1 AT E233089T1 AT 99960118 T AT99960118 T AT 99960118T AT 99960118 T AT99960118 T AT 99960118T AT E233089 T1 ATE233089 T1 AT E233089T1
Authority
AT
Austria
Prior art keywords
treating
composition
mycobacterium infections
preventing mycobacterium
preventing
Prior art date
Application number
AT99960118T
Other languages
English (en)
Inventor
Ze-Qi Xu
Yuh-Meei Lin
Michael T Flavin
Original Assignee
Sarawak Medichem Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarawak Medichem Pharmaceuticals Inc filed Critical Sarawak Medichem Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE233089T1 publication Critical patent/ATE233089T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT99960118T 1998-10-15 1999-10-14 Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen ATE233089T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10440998P 1998-10-15 1998-10-15
PCT/US1999/023689 WO2000021514A2 (en) 1998-10-15 1999-10-14 Method and composition for treating and preventing tuberculosis

Publications (1)

Publication Number Publication Date
ATE233089T1 true ATE233089T1 (de) 2003-03-15

Family

ID=22300328

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99960118T ATE233089T1 (de) 1998-10-15 1999-10-14 Verfahren und zusammensetzung zur behandlung und vorbeugung von mycobacterium infektionen

Country Status (12)

Country Link
US (2) US6268393B1 (de)
EP (1) EP1143952B1 (de)
CN (1) CN1334727A (de)
AP (1) AP2001002115A0 (de)
AT (1) ATE233089T1 (de)
AU (1) AU1705400A (de)
CA (1) CA2346813A1 (de)
DE (1) DE69905616T2 (de)
EA (1) EA200100347A1 (de)
ID (1) ID29547A (de)
OA (1) OA11666A (de)
WO (1) WO2000021514A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6677350B1 (en) * 1999-09-22 2004-01-13 Advanced Life Sciences, Inc. Beta-fluoroethyl thiourea compounds and use
AU758744B2 (en) * 2000-10-31 2003-03-27 F. Hoffmann-La Roche Ag Methods for the analysis of non-proteinaceous components using a protease from a bacillus strain
WO2002074777A2 (en) * 2001-03-16 2002-09-26 Sarawak Medichem Pharmaceuticals, Inc. Pyranocoumarin compounds as a novel pharmacophore with anti-tb activity
AU2003211734A1 (en) * 2002-03-08 2003-09-22 Kuraray Co., Ltd. Intermediates for production of (+)-calanolide a, processes for production of the intermediates and process for producing (+)-calanolide a with the same
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039476A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp Proceso para preparar derivados de 6-alquiliden penem
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
CA2574363A1 (en) * 2004-07-23 2006-02-02 Pharmacia & Upjohn Company Llc Enantioselective method for separating sustituted 2-trifluoromethyl-2h-chromene-3-carboxylic acid derivatives
EP1909786A2 (de) * 2005-07-27 2008-04-16 Wyeth a Corporation of the State of Delaware TRIZYKLISCHE 6-ALKYLIDEN-PENEM-ß-LACTAMASE-HEMMER UND ß-LACTAM-ANTIBIOTISCHE KOMBINATION: EIN BREITBANDANTIBIOTIKUM
JP2009502934A (ja) * 2005-07-27 2009-01-29 ワイス 二環式６−アルキリデンペネムβ−ラクタマーゼインヒビターおよびβ−ラクタム抗生物質の組み合わせ：広範なスペクトルの抗生物質
GT200600380A (es) * 2005-08-24 2007-03-29 Proceso para la preparacion de inhibidores de beta-lactamasa
CA2642754A1 (en) * 2006-02-13 2007-08-23 Trustees Of Boston University Compositions and methods for antibiotic potentiation and drug discovery
US20100234348A1 (en) * 2006-08-04 2010-09-16 Trustees Of Boston University Compositions and methods for potentiating antibiotic activity
ES2463689T3 (es) * 2007-11-05 2014-05-28 Institute Of Mataria Medica, Chinese Academy Of Medical Sciences Tetraciclodipiranil cumarinas y los usos anti VIH y anti-tuberculosis de las mismas
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same
CN102516217B (zh) * 2011-12-15 2014-03-12 四川大学 手性二氢色原酮骨架化合物及不对称合成
US9572809B2 (en) * 2012-07-18 2017-02-21 Spero Trinem, Inc. Combination therapy to treat Mycobacterium diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591770A (en) 1992-03-31 1997-01-07 The United States Of America As Represented By The Department Of Health And Human Services Calanolide and related antiretroviral compounds, compositions, and uses thereof
AU671827B2 (en) * 1992-03-31 1996-09-12 United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The Calanolide antiviral compounds, compositions and uses thereof
US5723631A (en) 1992-12-23 1998-03-03 Smithkline Beecham Corporation Coumarin derivatives as retroviral inhibitors
US6043271A (en) * 1994-08-03 2000-03-28 Sarawak Medichem Pharmaceuticals, Inc. Method for the preparation of (±)-calanolide A and intermediates thereof

Also Published As

Publication number Publication date
US6268393B1 (en) 2001-07-31
DE69905616T2 (de) 2003-08-14
EA200100347A1 (ru) 2001-10-22
OA11666A (en) 2004-12-08
ID29547A (id) 2001-09-06
AU1705400A (en) 2000-05-01
DE69905616D1 (de) 2003-04-03
US20010027209A1 (en) 2001-10-04
EP1143952B1 (de) 2003-02-26
WO2000021514A3 (en) 2001-08-23
WO2000021514A2 (en) 2000-04-20
CN1334727A (zh) 2002-02-06
AP2001002115A0 (en) 2001-06-30
EP1143952A2 (de) 2001-10-17
EP1143952A3 (de) 2002-09-11
CA2346813A1 (en) 2000-04-20

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Legal Events

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