ATE233406T1 - Verfahren zur bulk-anreicherung von einer zellpopulation oder zellsubpopulation - Google Patents
Verfahren zur bulk-anreicherung von einer zellpopulation oder zellsubpopulationInfo
- Publication number
- ATE233406T1 ATE233406T1 AT96943478T AT96943478T ATE233406T1 AT E233406 T1 ATE233406 T1 AT E233406T1 AT 96943478 T AT96943478 T AT 96943478T AT 96943478 T AT96943478 T AT 96943478T AT E233406 T1 ATE233406 T1 AT E233406T1
- Authority
- AT
- Austria
- Prior art keywords
- particles
- population
- sample
- subpopulation
- eliminated
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 6
- 239000000523 sample Substances 0.000 abstract 4
- 239000006228 supernatant Substances 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000005484 gravity Effects 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 238000004062 sedimentation Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55826895A | 1995-11-13 | 1995-11-13 | |
| PCT/US1996/017531 WO1997018473A1 (en) | 1995-11-13 | 1996-11-05 | Method and apparatus for bulk enrichment of a population or subpopulation of cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233406T1 true ATE233406T1 (de) | 2003-03-15 |
Family
ID=24228865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96943478T ATE233406T1 (de) | 1995-11-13 | 1996-11-05 | Verfahren zur bulk-anreicherung von einer zellpopulation oder zellsubpopulation |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6004743A (de) |
| EP (1) | EP0877941B1 (de) |
| JP (1) | JP2000500337A (de) |
| AT (1) | ATE233406T1 (de) |
| CA (1) | CA2236871A1 (de) |
| DE (1) | DE69626418T2 (de) |
| DK (1) | DK0877941T3 (de) |
| ES (1) | ES2194125T3 (de) |
| PT (1) | PT877941E (de) |
| WO (1) | WO1997018473A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19710496A1 (de) * | 1997-03-13 | 1998-09-17 | Boehringer Mannheim Gmbh | Verfahren zum Nachweis antigenspezifischer T-Zellen nach Anreicherung von mononukleären Zellpopulationen |
| US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| US7316932B2 (en) * | 2001-10-01 | 2008-01-08 | Stemcell Technologies Inc. | Method for separating cells |
| US9435799B2 (en) | 2002-07-31 | 2016-09-06 | Janssen Diagnostics, Inc. | Methods and reagents for improved selection of biological materials |
| DE10323901A1 (de) * | 2003-05-26 | 2005-01-05 | Institut Virion/Serion Gmbh | Verfahren und Testmittel zur Untersuchung und/oder zum Nachweis von Biomolekülen und/oder Wirkstoffen in Flüssigkeitsproben |
| US9790539B2 (en) | 2004-06-30 | 2017-10-17 | Russell Biotech, Inc. | Methods and reagents for improved selection of biological molecules |
| CA2599975C (en) * | 2005-03-03 | 2013-07-30 | University Of North Dakota | Surfaces coated with target-induced fluorescent compounds for detection of target elements |
| WO2007126151A1 (ja) * | 2006-04-28 | 2007-11-08 | Hitachi Maxell, Ltd. | 機能性粒子およびそれを用いた標的物質の分離方法 |
| WO2012048276A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| US10060911B2 (en) * | 2011-08-19 | 2018-08-28 | Protagen Aktiengesellschaft | Method for diagnosis of high-affinity binders and marker sequences |
| ES2602500T3 (es) | 2011-11-25 | 2017-02-21 | Miltenyi Biotec Gmbh | Método de separación celular |
| WO2015073913A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
| WO2015148704A1 (en) | 2014-03-25 | 2015-10-01 | Terumo Bct, Inc. | Passive replacement of media |
| EP3198006B1 (de) | 2014-09-26 | 2021-03-24 | Terumo BCT, Inc. | Geplante fütterung |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| CN117247899A (zh) | 2017-03-31 | 2023-12-19 | 泰尔茂比司特公司 | 细胞扩增 |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| JP2022513082A (ja) | 2018-11-19 | 2022-02-07 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | 免疫応答を調節するためのＩＲＥ１α－ＸＢＰ１シグナル伝達経路バイオマーカーの使用 |
| EP4314244B1 (de) | 2021-03-23 | 2025-07-23 | Terumo BCT, Inc. | Zellerfassung und -erweiterung |
| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928143A (en) * | 1972-02-23 | 1975-12-23 | Robert W Coughlin | Method of carrying out enzyme-catalyzed reactions |
| US4115535A (en) * | 1977-06-22 | 1978-09-19 | General Electric Company | Diagnostic method employing a mixture of normally separable protein-coated particles |
| US4487700A (en) * | 1983-02-18 | 1984-12-11 | Technicon Instruments Corporation | Method and apparatus for separating lymphocytes from anticoagulated blood |
| US4752563A (en) * | 1985-11-19 | 1988-06-21 | Coulter Corporation | Monoclonal antibody for recovery of leukocytes in human peripheral blood and method of recovery employing said monoclonal antibody |
| US5229268A (en) * | 1986-07-14 | 1993-07-20 | Abbott Laboratories | Method for diagnostic immunoassay by solid phase separation |
| NO162946C (no) * | 1987-08-21 | 1990-03-14 | Otto Soerensen | Anordning for magnetisk separasjon av celler. |
| US5238812A (en) * | 1987-03-13 | 1993-08-24 | Coulter Corporation | Method and apparatus for rapid mixing of small volumes for enhancing biological reactions |
| ATE81724T1 (de) * | 1987-11-09 | 1992-11-15 | Becton Dickinson Co | Verfahren zur analyse haematopoietischer zellen in einer probe. |
| US5256532A (en) * | 1988-05-02 | 1993-10-26 | Zynaxis Technologies, Inc. | Methods, reagents and test kits for determination of subpopulations of biological entities |
| US5576185A (en) * | 1994-04-15 | 1996-11-19 | Coulter Corporation | Method of positive or negative selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation |
| US5474687A (en) * | 1994-08-31 | 1995-12-12 | Activated Cell Therapy, Inc. | Methods for enriching CD34+ human hematopoietic progenitor cells |
-
1996
- 1996-11-05 EP EP96943478A patent/EP0877941B1/de not_active Expired - Lifetime
- 1996-11-05 DE DE69626418T patent/DE69626418T2/de not_active Expired - Lifetime
- 1996-11-05 PT PT96943478T patent/PT877941E/pt unknown
- 1996-11-05 DK DK96943478T patent/DK0877941T3/da active
- 1996-11-05 ES ES96943478T patent/ES2194125T3/es not_active Expired - Lifetime
- 1996-11-05 WO PCT/US1996/017531 patent/WO1997018473A1/en not_active Ceased
- 1996-11-05 CA CA002236871A patent/CA2236871A1/en not_active Abandoned
- 1996-11-05 AT AT96943478T patent/ATE233406T1/de not_active IP Right Cessation
- 1996-11-05 JP JP9518891A patent/JP2000500337A/ja active Pending
-
1997
- 1997-12-10 US US08/989,124 patent/US6004743A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0877941A1 (de) | 1998-11-18 |
| DK0877941T3 (da) | 2003-05-05 |
| ES2194125T3 (es) | 2003-11-16 |
| EP0877941B1 (de) | 2003-02-26 |
| DE69626418D1 (de) | 2003-04-03 |
| DE69626418T2 (de) | 2003-11-13 |
| JP2000500337A (ja) | 2000-01-18 |
| US6004743A (en) | 1999-12-21 |
| PT877941E (pt) | 2003-07-31 |
| CA2236871A1 (en) | 1997-05-22 |
| WO1997018473A1 (en) | 1997-05-22 |
| HK1016261A1 (en) | 1999-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0877941 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |