ATE233567T1 - Lhrh-antagonisten - Google Patents

Lhrh-antagonisten

Info

Publication number: ATE233567T1
Authority: AT; Austria
Prior art keywords: lhrh antagonists; lhrh; analogs; congeners; dosage
Prior art date: 1995-04-28

Application number

AT96913829T

Other languages

English (en)

Inventor

Cyril Y Bowers

Karl A Folkers

Anna Janecka

Original Assignee

Univ Texas

Univ Tulane

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-28

Filing date

1996-04-26

Publication date

2003-03-15

1996-04-26 Application filed by Univ Texas, Univ Tulane filed Critical Univ Texas

2003-03-15 Application granted granted Critical

2003-03-15 Publication of ATE233567T1 publication Critical patent/ATE233567T1/de

Links

229940124041 Luteinizing hormone releasing hormone (LHRH) antagonist Drugs 0.000 title 1
NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
230000002513 anti-ovulatory effect Effects 0.000 abstract 1
239000000039 congener Substances 0.000 abstract 1
XLXSAKCOAKORKW-UHFFFAOYSA-N gonadorelin Chemical class C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 XLXSAKCOAKORKW-UHFFFAOYSA-N 0.000 abstract 1
229960001340 histamine Drugs 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

AT96913829T 1995-04-28 1996-04-26 Lhrh-antagonisten ATE233567T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/430,602 US5656727A (en)	1992-09-15	1995-04-28	Antagonists of LHRH
PCT/US1996/005682 WO1996033729A1 (en)	1995-04-28	1996-04-26	Antagonists of lhrh

Publications (1)

Publication Number	Publication Date
ATE233567T1 true ATE233567T1 (de)	2003-03-15

Family

ID=23708267

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96913829T ATE233567T1 (de)	1995-04-28	1996-04-26	Lhrh-antagonisten

Country Status (10)

Country	Link
US (1)	US5656727A (de)
EP (1)	EP0822827B1 (de)
JP (1)	JPH11504335A (de)
AT (1)	ATE233567T1 (de)
AU (1)	AU703400B2 (de)
CA (1)	CA2219263A1 (de)
DE (1)	DE69626507T2 (de)
ES (1)	ES2191753T3 (de)
PT (1)	PT822827E (de)
WO (1)	WO1996033729A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2600554T3 (es)	2003-07-18	2017-02-09	Oakwood Laboratories L.L.C.	Prevención de la reducción del peso molecular del polímero, de la formación de impurezas y de la gelificación en composiciones poliméricas
JP4927729B2 (ja) *	2004-07-16	2012-05-09	オークウッドラボラトリーズ，エル．エル．シー．	性腺刺激ホルモン放出ホルモンアンタゴニスト
MX2009000709A (es) *	2006-07-18	2009-02-04	Sanofi Aventis	Anticuerpo antagonista contra epha2 para el tratamiento de cancer.
CA2727082C (en)	2008-06-12	2019-02-26	Syntaxin Limited	Fusion proteins for use in suppression of acromegaly
GB0820970D0 (en)	2008-11-17	2008-12-24	Syntaxin Ltd	Suppression of cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2872484A (en) *	1956-05-21	1959-02-03	American Cyanamid Co	Preparation of tetraalkyl-isothioureas
US4431635A (en) *	1979-06-13	1984-02-14	Coy David Howard	LH-RH Antagonists
AU9102582A (en) *	1981-12-10	1983-06-16	David Howard Coy	Lh-rh antagonists
FI832053L (fi) *	1982-06-10	1983-12-11	Syntex Inc	Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
US4444759A (en) *	1982-07-26	1984-04-24	The Salk Institute For Biological Studies	GnRH Antagonists II
US4504414A (en) *	1983-03-28	1985-03-12	Board Of Regents, The University Of Texas System	Synthetic pyridyl-alanyl decapeptides having antiovulatory activity
US4530920A (en) *	1983-11-07	1985-07-23	Syntex (U.S.A.) Inc.	Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
US4547370A (en) *	1983-11-29	1985-10-15	The Salk Institute For Biological Studies	GnRH Antagonists
US4652550A (en) *	1984-05-21	1987-03-24	The Salk Institute For Biological Studies	GnRH antagonists VII
IL74827A (en) *	1984-05-21	1989-06-30	Salk Inst For Biological Studi	Peptides active as gnrh antagonists and pharmaceutical compositions containing them
US4647653A (en) *	1984-08-23	1987-03-03	Tulane Educational Fund	Therapeutic peptides
US4565804A (en) *	1984-09-07	1986-01-21	The Salk Institute For Biological Studies	GnRH Antagonists VI
ZA862570B (en) *	1985-04-09	1986-12-30	Univ Tulane	Therapeutic decapeptides
AU5638886A (en) *	1985-04-19	1986-10-23	Syntex (U.S.A.) Inc.	Contraceptive methods for dogs using the decapeptide lhrh
EP0225746A3 (de) *	1985-11-14	1989-12-20	The Administrators of The Tulane Educational Fund	Therapeutische Dekapeptide
US4801577A (en) *	1987-02-05	1989-01-31	Syntex (U.S.A.) Inc.	Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4851385A (en) *	1987-07-15	1989-07-25	Indiana University Foundation	LHRH antagonist analogs having low histamine-release activity
US4935491A (en) *	1987-08-24	1990-06-19	Board Of Regents, The University Of Texas System	Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
DE68928278T2 (de) *	1988-02-10	1998-03-12	Tap Pharmaceuticals Inc	Lhrh-analog
US5140009A (en) *	1988-02-10	1992-08-18	Tap Pharmaceuticals, Inc.	Octapeptide LHRH antagonists
US5300492A (en) *	1988-02-10	1994-04-05	Tap Pharmaceuticals	LHRH analogs

1995
- 1995-04-28 US US08/430,602 patent/US5656727A/en not_active Expired - Fee Related
1996
- 1996-04-26 CA CA002219263A patent/CA2219263A1/en not_active Abandoned
- 1996-04-26 JP JP8532655A patent/JPH11504335A/ja not_active Ceased
- 1996-04-26 EP EP96913829A patent/EP0822827B1/de not_active Expired - Lifetime
- 1996-04-26 AT AT96913829T patent/ATE233567T1/de not_active IP Right Cessation
- 1996-04-26 DE DE69626507T patent/DE69626507T2/de not_active Expired - Fee Related
- 1996-04-26 WO PCT/US1996/005682 patent/WO1996033729A1/en not_active Ceased
- 1996-04-26 PT PT96913829T patent/PT822827E/pt unknown
- 1996-04-26 AU AU56670/96A patent/AU703400B2/en not_active Ceased
- 1996-04-26 ES ES96913829T patent/ES2191753T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2219263A1 (en)	1996-10-31
PT822827E (pt)	2003-07-31
EP0822827A1 (de)	1998-02-11
ES2191753T3 (es)	2003-09-16
US5656727A (en)	1997-08-12
WO1996033729A1 (en)	1996-10-31
EP0822827A4 (de)	2001-07-11
JPH11504335A (ja)	1999-04-20
DE69626507D1 (de)	2003-04-10
DE69626507T2 (de)	2003-11-13
EP0822827B1 (de)	2003-03-05
AU5667096A (en)	1996-11-18
AU703400B2 (en)	1999-03-25

Legal Events

Date

Code

Title

Description

2003-08-15

UEP

Publication of translation of european patent specification

Ref document number: 0822827

Country of ref document: EP

2006-01-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
OA09148A (en)	1991-10-31	Pharmacologically active CNS compounds.
MX9802383A (es)	1998-08-30	Derivados de pirimidina como antagonistas del receptor 5ht26.
EA199700111A1 (ru)	1997-12-30	Трициклические бензазепиновые антагонисты вазопрессина
MX9605023A (es)	1997-06-28	Compuestos substituidos de imidazolidin-2,4-diona como substancias farmaceuticamente activas.
DE59200181D1 (de)	1994-06-30	Brennstoffverteiler.
FI912621A7 (fi)	1991-12-02	Farmakologisesti aktiivisia keskushermostoon vaikuttavia yhdisteitä
DE59203994D1 (de)	1995-11-16	Brennstoffverteiler.
IT8522426A0 (it)	1985-10-10	Generatore termochimico di idrogeno a basso peso.
DE59203625D1 (de)	1995-10-19	Brennstoffverteiler.
FR2487917B1 (fr)	1985-12-27	Systeme d'alimentation de deux carburants
ATE233567T1 (de)	2003-03-15	Lhrh-antagonisten
FI912622A7 (fi)	1991-12-02	Farmakologisesti aktiivisia keskushermostoon vaikuttavia yhdisteitä
DE69318710D1 (en)	1998-06-25	Antitussivum
IT213678Z2 (it)	1990-01-22	Cabina per doccia a funzione multiple controllabili.
FI864249A7 (fi)	1986-10-21	Pirskotusputkirakenne leijukerrosta varten.
DE69015783D1 (de)	1995-02-16	Kraftstoffzufuhrschlauch.
FI940607A7 (fi)	1994-02-09	Imidatso(5,1-C)(1,4)bentsoksatsin-1-onijohdannaiset 5HT3-antagonisteina
ES522295A0 (es)	1984-08-16	Un derivado de trifluormetil-espiro(imidazolidina-4,3'-indolina)-2,2'5-triona.
DE59300621D1 (de)	1995-10-26	Kraftstoffzuleitung.
DE68910505D1 (de)	1993-12-09	Schnüffelventilanordnung.
FR2692261B1 (fr)	1994-09-02	Procédé de préparation d'un télogène actif.
IT8819903A0 (it)	1988-03-23	Procedimento perfezionato per la riduzione di composti organici mediante l'impiego di idruro di magnesio.
GB9218797D0 (en)	1992-10-21	Pharmacologically active compounds
ES1022124Y (es)	1993-08-01	"jeringuilla perfeccionada, de un solo uso"
AU4279585A (en)	1986-11-27	Device for adding disinfectant to the flushing water of a w.c.