ATE233765T1 - Tetracyclische verbindungen als dopamin-agonisten - Google Patents
Tetracyclische verbindungen als dopamin-agonistenInfo
- Publication number
- ATE233765T1 ATE233765T1 AT94912799T AT94912799T ATE233765T1 AT E233765 T1 ATE233765 T1 AT E233765T1 AT 94912799 T AT94912799 T AT 94912799T AT 94912799 T AT94912799 T AT 94912799T AT E233765 T1 ATE233765 T1 AT E233765T1
- Authority
- AT
- Austria
- Prior art keywords
- image
- dopamine agonists
- treatment
- tetracyclic compounds
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4342493A | 1993-04-06 | 1993-04-06 | |
| US20998294A | 1994-03-17 | 1994-03-17 | |
| PCT/US1994/002894 WO1994022858A1 (en) | 1993-04-06 | 1994-03-18 | Tetracyclic compounds as dopamine agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233765T1 true ATE233765T1 (de) | 2003-03-15 |
Family
ID=26720416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94912799T ATE233765T1 (de) | 1993-04-06 | 1994-03-18 | Tetracyclische verbindungen als dopamin-agonisten |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5597832A (de) |
| EP (1) | EP0690863B1 (de) |
| JP (1) | JP2710695B2 (de) |
| KR (1) | KR100383342B1 (de) |
| CN (1) | CN1046723C (de) |
| AT (1) | ATE233765T1 (de) |
| AU (1) | AU677842B2 (de) |
| BR (1) | BR9405972A (de) |
| DE (1) | DE69432217T2 (de) |
| DK (1) | DK0690863T3 (de) |
| ES (1) | ES2193158T3 (de) |
| FI (1) | FI954738L (de) |
| NO (1) | NO311762B1 (de) |
| PT (1) | PT690863E (de) |
| WO (1) | WO1994022858A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5659037A (en) * | 1994-08-18 | 1997-08-19 | Abbott Laboratories | Process for preparing chiral tetracyclic dopaminergic compounds |
| CN100360123C (zh) | 1995-01-13 | 2008-01-09 | 萨默塞特药品有限公司 | 应用去甲司来吉兰的方法和医药组合物 |
| CA2213197C (en) | 1995-02-15 | 2001-08-07 | Neurogen Corporation | Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands |
| US5668141A (en) * | 1996-04-02 | 1997-09-16 | Abbott Laboratories | Trans-2,6-,3,6-and 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzo[c]phenanthrene compounds as dopamine agonists |
| DE19644228A1 (de) * | 1996-10-24 | 1998-04-30 | Merck Patent Gmbh | Thienopyrimidine |
| EP1006794B1 (de) * | 1997-03-12 | 2007-11-28 | Robert W. Esmond | Verfahren zur behandlung oder prävention der alzheimerischen krankheit |
| US6193954B1 (en) | 1997-03-21 | 2001-02-27 | Abbott Laboratories | Formulations for pulmonary delivery of dopamine agonists |
| JP2001518520A (ja) | 1997-10-03 | 2001-10-16 | キャリー メディカル コーポレイション | ニコチンレセプターアンタゴニストおよび抗抑うつ薬または抗不安薬を含有するニコチン嗜癖を治療する組成物 |
| US20040058873A1 (en) * | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
| GB9828861D0 (en) * | 1998-12-31 | 1999-02-17 | Danbiosyst Uk | Compositions |
| US5969159A (en) * | 1999-02-16 | 1999-10-19 | Great Lakes Chemical Corporation | Synthesis of cyclopentyl 2-thienyl ketone tiletamine and tiletamine acid addition salts such as tiletamine hydrochloride |
| US6147226A (en) * | 1999-02-16 | 2000-11-14 | Great Lakes Chemical Corporation | Synthesis of cyclopentyl 2-thienyl ketone, tiletamine and tiletamine acid addition salts, such as tiletamine hydrochloride |
| US6638929B2 (en) | 1999-12-29 | 2003-10-28 | Wyeth | Tricyclic protein kinase inhibitors |
| MXPA03001472A (es) * | 2000-08-16 | 2003-06-06 | Upjohn Co | Compuestos para el tratamiento de trastornos adictivos. |
| DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
| US20070243240A9 (en) * | 2000-08-24 | 2007-10-18 | Fred Windt-Hanke | Transdermal therapeutic system |
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| AU2003217430B2 (en) | 2002-02-15 | 2008-10-23 | Darpharma, Inc. | Mono-ester and asymmetrically substituted Di-ester pro-drugs of the dopamine D1 receptor agonists |
| US20100168085A1 (en) * | 2003-05-22 | 2010-07-01 | Yesa Research And Development Co. Ltd. At The Weizmann Institute Of Science | Dopamine and agonists and antagonists thereof for modulation of suppressive activity of CD4+CD25+ regulatory T cells |
| WO2005055920A2 (en) * | 2003-12-09 | 2005-06-23 | Yeda Research And Development Co. Ltd. | Compositions and methods for treatment of psychiatric disorders |
| US20070155720A1 (en) * | 2003-12-23 | 2007-07-05 | Darpharma, Inc. | Co-administration of dopamine-receptor binding compounds |
| WO2007098462A2 (en) * | 2006-02-21 | 2007-08-30 | Purdue Research Foundation | Trans-fused chromenoisoquinolines, synthesis and methods for use |
| US9359303B2 (en) | 2009-04-21 | 2016-06-07 | Purdue Research Foundation | Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor |
| PT2822936T (pt) | 2012-03-07 | 2021-12-02 | Univ Of Delhi | Derivados da aminoquinolina e suas utilizações |
| CN103387583B (zh) * | 2012-05-09 | 2018-04-13 | 中国科学院上海药物研究所 | 二芳基并[a,g]喹嗪类化合物、其制备方法、药物组合物及其应用 |
| RU2537170C1 (ru) * | 2013-11-20 | 2014-12-27 | Войсковая Часть 41598 | Средство профилактики церебральной формы острой лучевой болезни |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2691024A (en) * | 1952-05-26 | 1954-10-05 | Schenley Ind Inc | Dihydropyrrolo-(3.2-c) quinoline derivatives |
| US3541100A (en) * | 1967-12-14 | 1970-11-17 | American Cyanamid Co | Benzheteroazolo(2,3-a)isoquinolium salts |
| GB1379387A (en) * | 1970-12-11 | 1975-01-02 | Agfa Gevaert | Photoconductive recording materials |
| US3943137A (en) * | 1973-07-09 | 1976-03-09 | University Of Kansas Endowment Association | Acronycine derivatives |
| NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
| US4282227A (en) * | 1980-05-22 | 1981-08-04 | Smithkline Corporation | Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines |
| US4340600A (en) * | 1980-05-22 | 1982-07-20 | Smithkline Corporation | Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines |
| US5047536A (en) * | 1989-03-17 | 1991-09-10 | Purdue Research Foundation | Hexahydrobenzo(A)phenanthridine compounds |
| AU4391493A (en) * | 1992-05-26 | 1993-12-30 | Purdue Research Foundation | Substituted-hexahydrobenzo(A)phenanthridines |
-
1994
- 1994-03-18 ES ES94912799T patent/ES2193158T3/es not_active Expired - Lifetime
- 1994-03-18 PT PT94912799T patent/PT690863E/pt unknown
- 1994-03-18 FI FI954738A patent/FI954738L/fi unknown
- 1994-03-18 CN CN94192241A patent/CN1046723C/zh not_active Expired - Lifetime
- 1994-03-18 DK DK94912799T patent/DK0690863T3/da active
- 1994-03-18 JP JP6522116A patent/JP2710695B2/ja not_active Expired - Lifetime
- 1994-03-18 EP EP94912799A patent/EP0690863B1/de not_active Expired - Lifetime
- 1994-03-18 WO PCT/US1994/002894 patent/WO1994022858A1/en not_active Ceased
- 1994-03-18 BR BR9405972A patent/BR9405972A/pt not_active Application Discontinuation
- 1994-03-18 AT AT94912799T patent/ATE233765T1/de active
- 1994-03-18 KR KR1019950704355A patent/KR100383342B1/ko not_active Expired - Lifetime
- 1994-03-18 DE DE69432217T patent/DE69432217T2/de not_active Expired - Lifetime
- 1994-03-18 AU AU65203/94A patent/AU677842B2/en not_active Expired
- 1994-11-10 US US08/337,348 patent/US5597832A/en not_active Expired - Lifetime
-
1995
- 1995-10-05 NO NO19953957A patent/NO311762B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0690863B1 (de) | 2003-03-05 |
| CN1046723C (zh) | 1999-11-24 |
| ES2193158T3 (es) | 2003-11-01 |
| NO311762B1 (no) | 2002-01-21 |
| FI954738A7 (fi) | 1995-12-05 |
| DE69432217T2 (de) | 2004-04-08 |
| NO953957L (no) | 1995-11-21 |
| WO1994022858A1 (en) | 1994-10-13 |
| EP0690863A1 (de) | 1996-01-10 |
| DK0690863T3 (da) | 2003-06-30 |
| AU6520394A (en) | 1994-10-24 |
| DE69432217D1 (de) | 2003-04-10 |
| JP2710695B2 (ja) | 1998-02-10 |
| FI954738A0 (fi) | 1995-10-05 |
| EP0690863A4 (de) | 1995-11-07 |
| US5597832A (en) | 1997-01-28 |
| PT690863E (pt) | 2003-07-31 |
| KR100383342B1 (ko) | 2003-08-25 |
| KR960701870A (ko) | 1996-03-28 |
| FI954738L (fi) | 1995-12-05 |
| AU677842B2 (en) | 1997-05-08 |
| NO953957D0 (no) | 1995-10-05 |
| JPH08508487A (ja) | 1996-09-10 |
| CN1124489A (zh) | 1996-06-12 |
| BR9405972A (pt) | 1995-12-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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