ATE233765T1 - Tetracyclische verbindungen als dopamin-agonisten - Google Patents
Tetracyclische verbindungen als dopamin-agonistenInfo
- Publication number
- ATE233765T1 ATE233765T1 AT94912799T AT94912799T ATE233765T1 AT E233765 T1 ATE233765 T1 AT E233765T1 AT 94912799 T AT94912799 T AT 94912799T AT 94912799 T AT94912799 T AT 94912799T AT E233765 T1 ATE233765 T1 AT E233765T1
- Authority
- AT
- Austria
- Prior art keywords
- image
- dopamine agonists
- treatment
- tetracyclic compounds
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4342493A | 1993-04-06 | 1993-04-06 | |
| US20998294A | 1994-03-17 | 1994-03-17 | |
| PCT/US1994/002894 WO1994022858A1 (en) | 1993-04-06 | 1994-03-18 | Tetracyclic compounds as dopamine agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233765T1 true ATE233765T1 (de) | 2003-03-15 |
Family
ID=26720416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94912799T ATE233765T1 (de) | 1993-04-06 | 1994-03-18 | Tetracyclische verbindungen als dopamin-agonisten |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5597832A (de) |
| EP (1) | EP0690863B1 (de) |
| JP (1) | JP2710695B2 (de) |
| KR (1) | KR100383342B1 (de) |
| CN (1) | CN1046723C (de) |
| AT (1) | ATE233765T1 (de) |
| AU (1) | AU677842B2 (de) |
| BR (1) | BR9405972A (de) |
| DE (1) | DE69432217T2 (de) |
| DK (1) | DK0690863T3 (de) |
| ES (1) | ES2193158T3 (de) |
| FI (1) | FI954738L (de) |
| NO (1) | NO311762B1 (de) |
| PT (1) | PT690863E (de) |
| WO (1) | WO1994022858A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5659037A (en) * | 1994-08-18 | 1997-08-19 | Abbott Laboratories | Process for preparing chiral tetracyclic dopaminergic compounds |
| JP3036847B2 (ja) | 1995-01-13 | 2000-04-24 | サマーセット・ファーマシューティカルズ・インコーポレイテッド | デスメチルセレギリンを用いる方法および医薬組成物 |
| WO1996025411A1 (en) | 1995-02-15 | 1996-08-22 | Neurogen Corporation | Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands |
| US5668141A (en) * | 1996-04-02 | 1997-09-16 | Abbott Laboratories | Trans-2,6-,3,6-and 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzo[c]phenanthrene compounds as dopamine agonists |
| DE19644228A1 (de) * | 1996-10-24 | 1998-04-30 | Merck Patent Gmbh | Thienopyrimidine |
| JP2001514663A (ja) * | 1997-03-12 | 2001-09-11 | エスモンド，ロバート ダブリュー． | アルツハイマー病を処置または予防するための方法 |
| US6193954B1 (en) | 1997-03-21 | 2001-02-27 | Abbott Laboratories | Formulations for pulmonary delivery of dopamine agonists |
| AU750808B2 (en) | 1997-10-03 | 2002-07-25 | Cary Medical Corporation | Compositon for the treatment of nicotine addiction containing a nicotine receptor antagonist and an anti-depressant or anti-anxiety drug |
| US20040058873A1 (en) * | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
| GB9828861D0 (en) * | 1998-12-31 | 1999-02-17 | Danbiosyst Uk | Compositions |
| US5969159A (en) * | 1999-02-16 | 1999-10-19 | Great Lakes Chemical Corporation | Synthesis of cyclopentyl 2-thienyl ketone tiletamine and tiletamine acid addition salts such as tiletamine hydrochloride |
| US6147226A (en) * | 1999-02-16 | 2000-11-14 | Great Lakes Chemical Corporation | Synthesis of cyclopentyl 2-thienyl ketone, tiletamine and tiletamine acid addition salts, such as tiletamine hydrochloride |
| US6638929B2 (en) * | 1999-12-29 | 2003-10-28 | Wyeth | Tricyclic protein kinase inhibitors |
| AU2001283393B2 (en) * | 2000-08-16 | 2005-09-22 | Pharmacia & Upjohn Company | Compounds for the treatment of addictive disorders |
| DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| US20070243240A9 (en) * | 2000-08-24 | 2007-10-18 | Fred Windt-Hanke | Transdermal therapeutic system |
| DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| AU2003217430B2 (en) * | 2002-02-15 | 2008-10-23 | Darpharma, Inc. | Mono-ester and asymmetrically substituted Di-ester pro-drugs of the dopamine D1 receptor agonists |
| WO2004103262A2 (en) * | 2003-05-22 | 2004-12-02 | Yeda Research And Development Co. Ltd. | Dopamine and agonists and antagonists thereof for modulation of suppressive activity of cd4+cd25+ regulatory t cells |
| WO2005055920A2 (en) * | 2003-12-09 | 2005-06-23 | Yeda Research And Development Co. Ltd. | Compositions and methods for treatment of psychiatric disorders |
| CN1964713A (zh) * | 2003-12-23 | 2007-05-16 | 达法尔摩公司 | 多巴胺－受体结合化合物的共同使用 |
| EP2010541A2 (de) * | 2006-02-21 | 2009-01-07 | Purdue Research Foundation | Übertragene chromenoisochinoline, synthese und anwendungsverfahren |
| WO2010124005A1 (en) | 2009-04-21 | 2010-10-28 | Purdue Research Foundation | Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor |
| US9567316B2 (en) | 2012-03-07 | 2017-02-14 | The Mclean Hospital Corporation | Aminoquinoline derivatives and uses thereof |
| CN103387583B (zh) * | 2012-05-09 | 2018-04-13 | 中国科学院上海药物研究所 | 二芳基并[a,g]喹嗪类化合物、其制备方法、药物组合物及其应用 |
| RU2537170C1 (ru) * | 2013-11-20 | 2014-12-27 | Войсковая Часть 41598 | Средство профилактики церебральной формы острой лучевой болезни |
| WO2026043936A1 (en) * | 2024-08-20 | 2026-02-26 | Universidad Del Desarrollo | Cysteine-bound short-chain fatty acid derivatives for the treatment of addictions |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2691024A (en) * | 1952-05-26 | 1954-10-05 | Schenley Ind Inc | Dihydropyrrolo-(3.2-c) quinoline derivatives |
| US3541100A (en) * | 1967-12-14 | 1970-11-17 | American Cyanamid Co | Benzheteroazolo(2,3-a)isoquinolium salts |
| GB1379387A (en) * | 1970-12-11 | 1975-01-02 | Agfa Gevaert | Photoconductive recording materials |
| US3943137A (en) * | 1973-07-09 | 1976-03-09 | University Of Kansas Endowment Association | Acronycine derivatives |
| NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
| US4282227A (en) * | 1980-05-22 | 1981-08-04 | Smithkline Corporation | Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines |
| US4340600A (en) * | 1980-05-22 | 1982-07-20 | Smithkline Corporation | Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines |
| US5047536A (en) * | 1989-03-17 | 1991-09-10 | Purdue Research Foundation | Hexahydrobenzo(A)phenanthridine compounds |
| DE69334206D1 (de) * | 1992-05-26 | 2008-04-03 | Purdue Research Foundation | Substituierte hexahydrobenzo(a) phenanthridine |
-
1994
- 1994-03-18 PT PT94912799T patent/PT690863E/pt unknown
- 1994-03-18 BR BR9405972A patent/BR9405972A/pt not_active Application Discontinuation
- 1994-03-18 WO PCT/US1994/002894 patent/WO1994022858A1/en not_active Ceased
- 1994-03-18 AT AT94912799T patent/ATE233765T1/de active
- 1994-03-18 EP EP94912799A patent/EP0690863B1/de not_active Expired - Lifetime
- 1994-03-18 CN CN94192241A patent/CN1046723C/zh not_active Expired - Lifetime
- 1994-03-18 KR KR1019950704355A patent/KR100383342B1/ko not_active Expired - Lifetime
- 1994-03-18 FI FI954738A patent/FI954738L/fi unknown
- 1994-03-18 AU AU65203/94A patent/AU677842B2/en not_active Expired
- 1994-03-18 JP JP6522116A patent/JP2710695B2/ja not_active Expired - Lifetime
- 1994-03-18 ES ES94912799T patent/ES2193158T3/es not_active Expired - Lifetime
- 1994-03-18 DE DE69432217T patent/DE69432217T2/de not_active Expired - Lifetime
- 1994-03-18 DK DK94912799T patent/DK0690863T3/da active
- 1994-11-10 US US08/337,348 patent/US5597832A/en not_active Expired - Lifetime
-
1995
- 1995-10-05 NO NO19953957A patent/NO311762B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1124489A (zh) | 1996-06-12 |
| BR9405972A (pt) | 1995-12-12 |
| AU677842B2 (en) | 1997-05-08 |
| JP2710695B2 (ja) | 1998-02-10 |
| DE69432217D1 (de) | 2003-04-10 |
| NO953957L (no) | 1995-11-21 |
| EP0690863B1 (de) | 2003-03-05 |
| NO953957D0 (no) | 1995-10-05 |
| FI954738A7 (fi) | 1995-12-05 |
| WO1994022858A1 (en) | 1994-10-13 |
| CN1046723C (zh) | 1999-11-24 |
| FI954738L (fi) | 1995-12-05 |
| EP0690863A4 (de) | 1995-11-07 |
| ES2193158T3 (es) | 2003-11-01 |
| JPH08508487A (ja) | 1996-09-10 |
| KR100383342B1 (ko) | 2003-08-25 |
| DE69432217T2 (de) | 2004-04-08 |
| PT690863E (pt) | 2003-07-31 |
| KR960701870A (ko) | 1996-03-28 |
| AU6520394A (en) | 1994-10-24 |
| EP0690863A1 (de) | 1996-01-10 |
| DK0690863T3 (da) | 2003-06-30 |
| US5597832A (en) | 1997-01-28 |
| NO311762B1 (no) | 2002-01-21 |
| FI954738A0 (fi) | 1995-10-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69432217D1 (de) | Tetracyclische verbindungen als dopamin-agonisten | |
| GEP20022676B (en) | 4-Phenyl-Pyridine Derivatives, Method for Their Production and Their Use for Treatment of Disorders Caused by Antagonist of NK-1 Receptors | |
| ATE216996T1 (de) | Kondensierte trizyklische, stickstoffenthaltende verbindungen als substanz p rezeptor antagonisten | |
| ID22636A (id) | Zat-zat terapeutik | |
| ES2134847T3 (es) | Derivados de taxol. | |
| BG106301A (en) | Quinuclidine derivatives and their use as muscarinic m3 receptor ligands | |
| CA2286723A1 (en) | Tricyclic compounds | |
| BG107120A (bg) | Нови бавнодействащи бетамиметици, метод за тяхното получаване и приложението им като лекарствени средства | |
| ZA9811576B (en) | Anilide derivative, production and use thereof. | |
| ATE401311T1 (de) | Kondensierte heterozyklische verbindungen als petidase inhibitoren | |
| CA2239705A1 (en) | Quinazoline-4-one ampa antagonists | |
| GB0021421D0 (en) | Compounds | |
| ES2122258T3 (es) | 4-azaesteroides 15 sustituidos. | |
| EP1189900A4 (de) | Heterocyclische aminopyrrolidon-derivate als melatonergene wirkstoffe | |
| ATE88461T1 (de) | Substituierte oximether und fungizide, die diese verbindungen enthalten. | |
| NZ316312A (en) | Novel fused isoquinolines as dopamine receptor ligands | |
| IT1241029B (it) | Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione | |
| CA2159481A1 (en) | Tetracyclic compounds as dopamine agonists | |
| CA2213197A1 (en) | Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands | |
| ES8203358A1 (es) | Metodo de producir lactamas antihipertensoras | |
| NZ512754A (en) | Remedial agent for erectile dysfunction containing a 3(2H)-pyridazinone derivative | |
| PT1192161E (pt) | Cromeno¬4,3,2/de| isoquinolinas como ligandos potentes de receptores de dopamina | |
| DE69016266D1 (de) | Aminoketonverbindungen. | |
| WO2002024641A1 (en) | Tricyclic indole compounds having affinity for serotonin receptor | |
| CA2245926A1 (en) | 7-phenyl-1,4-diazepane compounds, process for their preparation, and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0690863 Country of ref document: EP |