ATE234283T1 - Indolecarbonsäurederivate und ihre verwendung als arzneimittel - Google Patents
Indolecarbonsäurederivate und ihre verwendung als arzneimittelInfo
- Publication number
- ATE234283T1 ATE234283T1 AT98942786T AT98942786T ATE234283T1 AT E234283 T1 ATE234283 T1 AT E234283T1 AT 98942786 T AT98942786 T AT 98942786T AT 98942786 T AT98942786 T AT 98942786T AT E234283 T1 ATE234283 T1 AT E234283T1
- Authority
- AT
- Austria
- Prior art keywords
- acid derivatives
- medicinal products
- alkyl
- indolecarboxylic acid
- chr3r4
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Cosmetics (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9711076A FR2768146B1 (fr) | 1997-09-05 | 1997-09-05 | Nouveaux composes de la famille des indole-carboxyliques et leur utilisation |
| PCT/FR1998/001853 WO1999012905A1 (fr) | 1997-09-05 | 1998-08-26 | Composes indole-carboxyliques et leur utilisation comme composes pharmaceutiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234283T1 true ATE234283T1 (de) | 2003-03-15 |
Family
ID=9510808
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03000188T ATE334962T1 (de) | 1997-09-05 | 1998-08-26 | Indolecarbonsäurederivate und ihre verwendung als arzneimittel |
| AT98942786T ATE234283T1 (de) | 1997-09-05 | 1998-08-26 | Indolecarbonsäurederivate und ihre verwendung als arzneimittel |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03000188T ATE334962T1 (de) | 1997-09-05 | 1998-08-26 | Indolecarbonsäurederivate und ihre verwendung als arzneimittel |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6448285B1 (de) |
| EP (2) | EP1302460B1 (de) |
| JP (2) | JP4090515B2 (de) |
| AT (2) | ATE334962T1 (de) |
| AU (1) | AU9079198A (de) |
| CA (2) | CA2271085C (de) |
| DE (2) | DE69812073T2 (de) |
| ES (2) | ES2268169T3 (de) |
| FR (1) | FR2768146B1 (de) |
| WO (1) | WO1999012905A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6495538B2 (en) * | 1999-06-23 | 2002-12-17 | Zinc Therapeutics, Canada Inc. | Zinc ionophores as therapeutic agents |
| FR2796279B1 (fr) * | 1999-07-16 | 2001-09-21 | Oreal | Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour le traitement de la seborrhee |
| FR2796274B1 (fr) * | 1999-07-16 | 2001-09-21 | Oreal | Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
| AU2002357003A1 (en) * | 2001-12-28 | 2003-07-24 | Guilford Pharmaceuticals Inc. | Indoles as naaladase inhibitors |
| US7125906B2 (en) | 2002-04-03 | 2006-10-24 | Astrazeneca Ab | Indole derivatives having anti-angiogenetic activity |
| US7041636B1 (en) | 2004-01-22 | 2006-05-09 | Benton Melody M | Composition for counteracting hair loss |
| UA95788C2 (en) | 2005-12-15 | 2011-09-12 | Ф. Хоффманн-Ля Рош Аг | Fused pyrrole derivatives |
| US20080160509A1 (en) * | 2006-09-13 | 2008-07-03 | Pacific Bioscience Laboratories, Inc. | Assays for predicting and assessing predisposition to male pattern baldness |
| US20080063673A1 (en) * | 2006-09-13 | 2008-03-13 | Akridge Robert E | Method and kit for treatment/prevention of hair loss |
| ES2452343T3 (es) * | 2006-09-29 | 2014-04-01 | Glaxosmithkline Llc | Compuestos de indol sustituidos |
| CA2673254C (en) * | 2006-12-22 | 2013-09-10 | Schering Corporation | 4,5-ring annulated indole derivatives for treating or preventing of hcv and related viral infections |
| CA2674831A1 (en) | 2006-12-22 | 2008-11-13 | Schering Corporation | 5,6-ring annulated indole derivatives and methods of use thereof |
| JP5079818B2 (ja) | 2006-12-22 | 2012-11-21 | メルク・シャープ・アンド・ドーム・コーポレーション | Hcvおよび関連するウイルス疾患の治療または予防のための4,5−環インドール誘導体 |
| KR20090001013A (ko) * | 2007-06-29 | 2009-01-08 | 주식회사 웰스킨 | 인돌-3-알킬카복실산을 함유하는 여드름 치료제 및 피지분비 억제제, 및 이를 포함하는 광역학적 치료용 키트 |
| AU2008295484B2 (en) | 2007-08-29 | 2013-09-26 | Merck Sharp & Dohme Llc | Substituted indole derivatives and methods of use thereof |
| PE20090994A1 (es) | 2007-08-29 | 2009-08-03 | Schering Corp | Derivados de azaindol 2,3-sustituidos como agentes antivirales |
| CN101842353A (zh) | 2007-08-29 | 2010-09-22 | 先灵公司 | 用于治疗病毒感染的2,3-取代的吲哚衍生物 |
| EP2222660B1 (de) | 2007-11-16 | 2014-03-26 | Merck Sharp & Dohme Corp. | 3-heterocyclylsubstituierte indolderivate und verfahren zu deren anwendung |
| JP5416708B2 (ja) | 2007-11-16 | 2014-02-12 | メルク・シャープ・アンド・ドーム・コーポレーション | 3−アミノスルホニル置換インドール誘導体およびそれらの使用方法 |
| WO2009152200A1 (en) | 2008-06-13 | 2009-12-17 | Schering Corporation | Tricyclic indole derivatives and methods of use thereof |
| WO2010143803A2 (en) * | 2009-06-08 | 2010-12-16 | Industry Foundation Of Chonnam National University | New nicotinamide derivatives with anti-androgen effects, processes of preparing, and antiandrogens comprising the same |
| FR2953722B1 (fr) | 2009-12-16 | 2012-03-09 | Expanscience Lab | Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles |
| KR101213495B1 (ko) * | 2010-06-03 | 2013-01-14 | 삼성디스플레이 주식회사 | 유기 발광 소자 |
| JP6910027B2 (ja) * | 2017-03-29 | 2021-07-28 | 株式会社コーセー | チロシナーゼ活性阻害剤、メラニン産生抑制剤及び美白剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB359876A (en) | 1930-05-20 | 1931-10-29 | British Thomson Houston Co Ltd | Improvements in and relating to polyphase thermionic generators |
| BE794483A (fr) * | 1972-01-26 | 1973-07-24 | Boehringer Mannheim Gmbh | Derives de l'acide indol-carbonique a effet hypoglycemiant et procedes pour leur preparation |
| LU86347A1 (fr) | 1986-03-06 | 1987-11-11 | Oreal | Compositions pour la coloration de la peau a base de derives d'indole |
| FR2686345A1 (fr) * | 1992-01-16 | 1993-07-23 | Oreal | Produit a base de particules minerales colorees comportant un pigment melanique, son procede de preparation et son utilisation en cosmetique. |
| FR2689898B1 (fr) * | 1992-04-08 | 1994-06-10 | Oreal | Pigments comportant un support inorganique et le produit de reaction d'un derive indolique et d'un derive quinonique, leur procede de preparation et leur utilisation en cosmetique. |
| JPH07507574A (ja) * | 1993-04-05 | 1995-08-24 | 藤沢薬品工業株式会社 | テストステロン5α−レダクターゼ阻害剤用インドール誘導体 |
| DE4314317A1 (de) * | 1993-04-30 | 1994-11-03 | Henkel Kgaa | Isatinhaltige Mittel zum Färben von keratinhaltigen Fasern |
| WO1997035572A1 (en) * | 1996-03-28 | 1997-10-02 | Smithkline Beecham Corporation | Carboxylic acid indole inhibitors of chemokines |
| GB9716657D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
-
1997
- 1997-09-05 FR FR9711076A patent/FR2768146B1/fr not_active Expired - Fee Related
-
1998
- 1998-08-26 DE DE69812073T patent/DE69812073T2/de not_active Expired - Fee Related
- 1998-08-26 EP EP03000188A patent/EP1302460B1/de not_active Expired - Lifetime
- 1998-08-26 WO PCT/FR1998/001853 patent/WO1999012905A1/fr not_active Ceased
- 1998-08-26 ES ES03000188T patent/ES2268169T3/es not_active Expired - Lifetime
- 1998-08-26 AT AT03000188T patent/ATE334962T1/de not_active IP Right Cessation
- 1998-08-26 DE DE69835460T patent/DE69835460T2/de not_active Expired - Fee Related
- 1998-08-26 CA CA002271085A patent/CA2271085C/fr not_active Expired - Fee Related
- 1998-08-26 AU AU90791/98A patent/AU9079198A/en not_active Abandoned
- 1998-08-26 AT AT98942786T patent/ATE234283T1/de not_active IP Right Cessation
- 1998-08-26 JP JP51515199A patent/JP4090515B2/ja not_active Expired - Fee Related
- 1998-08-26 ES ES98942786T patent/ES2195382T3/es not_active Expired - Lifetime
- 1998-08-26 CA CA002569685A patent/CA2569685A1/fr not_active Abandoned
- 1998-08-26 US US09/297,636 patent/US6448285B1/en not_active Expired - Fee Related
- 1998-08-26 EP EP98942786A patent/EP0964852B1/de not_active Expired - Lifetime
-
2002
- 2002-06-24 US US10/176,674 patent/US6596753B2/en not_active Expired - Fee Related
-
2003
- 2003-07-09 JP JP2003272606A patent/JP2004035566A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE334962T1 (de) | 2006-08-15 |
| EP0964852A1 (de) | 1999-12-22 |
| WO1999012905A1 (fr) | 1999-03-18 |
| CA2271085A1 (fr) | 1999-03-18 |
| DE69835460D1 (de) | 2006-09-14 |
| EP1302460A1 (de) | 2003-04-16 |
| FR2768146B1 (fr) | 2000-05-05 |
| EP0964852B1 (de) | 2003-03-12 |
| US6448285B1 (en) | 2002-09-10 |
| JP2004035566A (ja) | 2004-02-05 |
| US20030050325A1 (en) | 2003-03-13 |
| ES2268169T3 (es) | 2007-03-16 |
| CA2271085C (fr) | 2007-04-17 |
| CA2569685A1 (fr) | 1999-03-18 |
| ES2195382T3 (es) | 2003-12-01 |
| US6596753B2 (en) | 2003-07-22 |
| JP2000508352A (ja) | 2000-07-04 |
| DE69812073T2 (de) | 2003-09-25 |
| DE69835460T2 (de) | 2007-07-26 |
| FR2768146A1 (fr) | 1999-03-12 |
| DE69812073D1 (de) | 2003-04-17 |
| AU9079198A (en) | 1999-03-29 |
| JP4090515B2 (ja) | 2008-05-28 |
| EP1302460B1 (de) | 2006-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |