ATE234283T1 - Indolecarbonsäurederivate und ihre verwendung als arzneimittel - Google Patents

Indolecarbonsäurederivate und ihre verwendung als arzneimittel

Info

Publication number
ATE234283T1
ATE234283T1 AT98942786T AT98942786T ATE234283T1 AT E234283 T1 ATE234283 T1 AT E234283T1 AT 98942786 T AT98942786 T AT 98942786T AT 98942786 T AT98942786 T AT 98942786T AT E234283 T1 ATE234283 T1 AT E234283T1
Authority
AT
Austria
Prior art keywords
acid derivatives
medicinal products
alkyl
indolecarboxylic acid
chr3r4
Prior art date
Application number
AT98942786T
Other languages
English (en)
Inventor
Bruno Bernard
Catherine Gerst
Jean-Baptiste Galey
Maria Dalko
Patrick Pichaud
Original Assignee
Oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal filed Critical Oreal
Application granted granted Critical
Publication of ATE234283T1 publication Critical patent/ATE234283T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT98942786T 1997-09-05 1998-08-26 Indolecarbonsäurederivate und ihre verwendung als arzneimittel ATE234283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9711076A FR2768146B1 (fr) 1997-09-05 1997-09-05 Nouveaux composes de la famille des indole-carboxyliques et leur utilisation
PCT/FR1998/001853 WO1999012905A1 (fr) 1997-09-05 1998-08-26 Composes indole-carboxyliques et leur utilisation comme composes pharmaceutiques

Publications (1)

Publication Number Publication Date
ATE234283T1 true ATE234283T1 (de) 2003-03-15

Family

ID=9510808

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03000188T ATE334962T1 (de) 1997-09-05 1998-08-26 Indolecarbonsäurederivate und ihre verwendung als arzneimittel
AT98942786T ATE234283T1 (de) 1997-09-05 1998-08-26 Indolecarbonsäurederivate und ihre verwendung als arzneimittel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03000188T ATE334962T1 (de) 1997-09-05 1998-08-26 Indolecarbonsäurederivate und ihre verwendung als arzneimittel

Country Status (10)

Country Link
US (2) US6448285B1 (de)
EP (2) EP0964852B1 (de)
JP (2) JP4090515B2 (de)
AT (2) ATE334962T1 (de)
AU (1) AU9079198A (de)
CA (2) CA2569685A1 (de)
DE (2) DE69812073T2 (de)
ES (2) ES2195382T3 (de)
FR (1) FR2768146B1 (de)
WO (1) WO1999012905A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495538B2 (en) * 1999-06-23 2002-12-17 Zinc Therapeutics, Canada Inc. Zinc ionophores as therapeutic agents
FR2796274B1 (fr) * 1999-07-16 2001-09-21 Oreal Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
FR2796279B1 (fr) 1999-07-16 2001-09-21 Oreal Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour le traitement de la seborrhee
US7148250B2 (en) * 2001-12-28 2006-12-12 Guilford Pharmaceuticals Inc. Indoles as NAALADase inhibitors
JP2005532280A (ja) 2002-04-03 2005-10-27 アストラゼネカ アクチボラグ 化合物
US7041636B1 (en) 2004-01-22 2006-05-09 Benton Melody M Composition for counteracting hair loss
UA95788C2 (en) 2005-12-15 2011-09-12 Ф. Хоффманн-Ля Рош Аг Fused pyrrole derivatives
US20080160509A1 (en) * 2006-09-13 2008-07-03 Pacific Bioscience Laboratories, Inc. Assays for predicting and assessing predisposition to male pattern baldness
US20080063673A1 (en) * 2006-09-13 2008-03-13 Akridge Robert E Method and kit for treatment/prevention of hair loss
WO2008042571A2 (en) * 2006-09-29 2008-04-10 Smithkline Beecham Corporation Substituted indole compounds
KR20090106539A (ko) * 2006-12-22 2009-10-09 쉐링 코포레이션 Ｈｃｖ 및 관련 바이러스 감염을 치료 또는 예방하기 위한 4,5-환 환상 인돌 유도체
JP5079818B2 (ja) 2006-12-22 2012-11-21 メルク・シャープ・アンド・ドーム・コーポレーション Ｈｃｖおよび関連するウイルス疾患の治療または予防のための４，５−環インドール誘導体
JP5055377B2 (ja) 2006-12-22 2012-10-24 シェーリング コーポレイション ［５，６−環］環形成インドール誘導体およびその使用方法
KR20090001013A (ko) * 2007-06-29 2009-01-08 주식회사 웰스킨 인돌-3-알킬카복실산을 함유하는 여드름 치료제 및 피지분비 억제제, 및 이를 포함하는 광역학적 치료용 키트
RU2010111550A (ru) 2007-08-29 2011-10-10 Шеринг Корпорейшн (US) 2,3-замещенные индольные производные для лечения вирусных инфекций
WO2009032124A1 (en) 2007-08-29 2009-03-12 Schering Corporation Substituted indole derivatives and methods of use thereof
EP2195317B1 (de) 2007-08-29 2012-01-18 Schering Corporation 2,3-substituierte azaindolderivate zur behandlung von virusinfektionen
CN102317285A (zh) 2007-11-16 2012-01-11 先灵公司 3-氨基磺酰基取代的吲哚衍生物及其使用方法
US8765757B2 (en) 2007-11-16 2014-07-01 Merck Sharp & Dohme Corp. 3-heterocyclic substituted indole derivatives and methods of use thereof
JP5580814B2 (ja) 2008-06-13 2014-08-27 メルク・シャープ・アンド・ドーム・コーポレーション ３環式インドール誘導体およびその使用方法
WO2010143803A2 (en) * 2009-06-08 2010-12-16 Industry Foundation Of Chonnam National University New nicotinamide derivatives with anti-androgen effects, processes of preparing, and antiandrogens comprising the same
FR2953722B1 (fr) 2009-12-16 2012-03-09 Expanscience Lab Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles
KR101213495B1 (ko) * 2010-06-03 2013-01-14 삼성디스플레이 주식회사 유기 발광 소자
JP6910027B2 (ja) * 2017-03-29 2021-07-28 株式会社コーセー チロシナーゼ活性阻害剤、メラニン産生抑制剤及び美白剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB359876A (en) 1930-05-20 1931-10-29 British Thomson Houston Co Ltd Improvements in and relating to polyphase thermionic generators
BE794483A (fr) * 1972-01-26 1973-07-24 Boehringer Mannheim Gmbh Derives de l'acide indol-carbonique a effet hypoglycemiant et procedes pour leur preparation
LU86347A1 (fr) * 1986-03-06 1987-11-11 Oreal Compositions pour la coloration de la peau a base de derives d'indole
FR2686345A1 (fr) * 1992-01-16 1993-07-23 Oreal Produit a base de particules minerales colorees comportant un pigment melanique, son procede de preparation et son utilisation en cosmetique.
FR2689898B1 (fr) * 1992-04-08 1994-06-10 Oreal Pigments comportant un support inorganique et le produit de reaction d'un derive indolique et d'un derive quinonique, leur procede de preparation et leur utilisation en cosmetique.
US5530019A (en) * 1993-04-05 1996-06-25 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives useful as testosterone 5α-reductase inhibitors
DE4314317A1 (de) * 1993-04-30 1994-11-03 Henkel Kgaa Isatinhaltige Mittel zum Färben von keratinhaltigen Fasern
WO1997035572A1 (en) * 1996-03-28 1997-10-02 Smithkline Beecham Corporation Carboxylic acid indole inhibitors of chemokines
GB9716657D0 (en) * 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
US6448285B1 (en) 2002-09-10
FR2768146A1 (fr) 1999-03-12
CA2569685A1 (fr) 1999-03-18
FR2768146B1 (fr) 2000-05-05
JP2004035566A (ja) 2004-02-05
EP1302460A1 (de) 2003-04-16
CA2271085C (fr) 2007-04-17
US20030050325A1 (en) 2003-03-13
JP4090515B2 (ja) 2008-05-28
JP2000508352A (ja) 2000-07-04
DE69812073D1 (de) 2003-04-17
EP1302460B1 (de) 2006-08-02
ES2195382T3 (es) 2003-12-01
ATE334962T1 (de) 2006-08-15
WO1999012905A1 (fr) 1999-03-18
EP0964852B1 (de) 2003-03-12
ES2268169T3 (es) 2007-03-16
EP0964852A1 (de) 1999-12-22
DE69812073T2 (de) 2003-09-25
DE69835460T2 (de) 2007-07-26
US6596753B2 (en) 2003-07-22
CA2271085A1 (fr) 1999-03-18
AU9079198A (en) 1999-03-29
DE69835460D1 (de) 2006-09-14

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties