ATE234614T1 - Verwendung von selegilin zur behandlung von gehörverlust bei säugetieren - Google Patents
Verwendung von selegilin zur behandlung von gehörverlust bei säugetierenInfo
- Publication number
- ATE234614T1 ATE234614T1 AT96917093T AT96917093T ATE234614T1 AT E234614 T1 ATE234614 T1 AT E234614T1 AT 96917093 T AT96917093 T AT 96917093T AT 96917093 T AT96917093 T AT 96917093T AT E234614 T1 ATE234614 T1 AT E234614T1
- Authority
- AT
- Austria
- Prior art keywords
- selegiline
- mammals
- hearing loss
- treat hearing
- treat
- Prior art date
Links
- 206010011878 Deafness Diseases 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title abstract 2
- 230000010370 hearing loss Effects 0.000 title abstract 2
- 231100000888 hearing loss Toxicity 0.000 title abstract 2
- 208000016354 hearing loss disease Diseases 0.000 title abstract 2
- MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical compound C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 title abstract 2
- 229960003946 selegiline Drugs 0.000 title abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/475,186 US5561163A (en) | 1990-08-31 | 1995-06-07 | Treating hearing loss with deprenyl |
| PCT/US1996/008642 WO1996040094A1 (en) | 1995-06-07 | 1996-06-03 | Use of selegiline to treat hearing loss in mammals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234614T1 true ATE234614T1 (de) | 2003-04-15 |
Family
ID=23886552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96917093T ATE234614T1 (de) | 1995-06-07 | 1996-06-03 | Verwendung von selegilin zur behandlung von gehörverlust bei säugetieren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5561163A (de) |
| EP (1) | EP0831798B1 (de) |
| JP (1) | JP3094305B2 (de) |
| AT (1) | ATE234614T1 (de) |
| AU (1) | AU693704B2 (de) |
| CA (1) | CA2221255C (de) |
| DE (1) | DE69626816T2 (de) |
| ES (1) | ES2194104T3 (de) |
| WO (1) | WO1996040094A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050222127A1 (en) * | 2004-03-30 | 2005-10-06 | Alcon, Inc. | Use of Rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance |
| WO2005118539A1 (en) | 2004-06-01 | 2005-12-15 | F.Hoffmann-La Roche Ag | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor |
| PL2970890T3 (pl) | 2013-03-14 | 2020-11-16 | The Brigham And Women's Hospital, Inc. | Kompozycje i sposoby ekspansji i hodowli nabłonkowych komórek macierzystych |
| EP3189134A1 (de) | 2014-09-03 | 2017-07-12 | The Brigham and Women's Hospital, Inc. | Zusammensetzungen, systeme und verfahren zur erzeugung von innenohrhaarzellen zur behandlung von gehörverlust |
| US11021687B2 (en) | 2016-01-08 | 2021-06-01 | The Brigham And Women's Hospital, Inc. | Production of differentiated enteroendocrine cells and insulin producing cells |
| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| US11260130B2 (en) | 2016-03-02 | 2022-03-01 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV |
| US10213511B2 (en) | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| EP3562827A1 (de) | 2016-12-30 | 2019-11-06 | Frequency Therapeutics, Inc. | 1h-pyrrol-2,5-dion-verbindungen und verfahren zur verwendung davon zur induktion der selbsterneuerung von unterstützenden stamm-/vorläuferzellen |
| US11617745B2 (en) | 2018-08-17 | 2023-04-04 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by downregulating FOXO |
| JP2021533788A (ja) | 2018-08-17 | 2021-12-09 | フリークエンシー セラピューティクス インコーポレイテッド | Ｊａｇ−１を上方制御することにより有毛細胞を生成するための組成物及び方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA871155A (en) * | 1971-05-18 | Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt | Optically active phenyl isopropylamine derivatives having pharmaceutical properties and their preparation | |
| HU187775B (en) * | 1982-07-14 | 1986-02-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | New process for producing propargile-amines of pharmaceutical activity |
| HU193662B (en) * | 1983-12-20 | 1987-11-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing synergetic pharmaceutical composition of antidepressive aktivity |
| US4916151A (en) * | 1985-12-05 | 1990-04-10 | Merrell Dow Pharmaceuticals Inc. | Method of treating parkinson's syndrome |
| US4871550A (en) * | 1986-09-05 | 1989-10-03 | Millman Phillip L | Nutrient composition for athletes and method of making and using the same |
| US4861800A (en) * | 1987-08-18 | 1989-08-29 | Buyske Donald A | Method for administering the drug deprenyl so as to minimize the danger of side effects |
| US5192808A (en) * | 1990-08-31 | 1993-03-09 | Deprenyl Animal Health, Inc. | Therapeutic effect of L-deprenyl in the management of pituitary-dependent hyperadrenocorticism (cushing's disease) |
| CA2039194C (en) * | 1990-08-31 | 1997-01-28 | Norton W. Milgram | Uses of l-deprenyl and compositions for same |
| SE9301112D0 (sv) * | 1993-04-02 | 1993-04-02 | Orion-Yhtymae Oy | A new composition |
-
1995
- 1995-06-07 US US08/475,186 patent/US5561163A/en not_active Expired - Lifetime
-
1996
- 1996-06-03 AU AU59772/96A patent/AU693704B2/en not_active Ceased
- 1996-06-03 ES ES96917093T patent/ES2194104T3/es not_active Expired - Lifetime
- 1996-06-03 DE DE69626816T patent/DE69626816T2/de not_active Expired - Fee Related
- 1996-06-03 AT AT96917093T patent/ATE234614T1/de not_active IP Right Cessation
- 1996-06-03 EP EP96917093A patent/EP0831798B1/de not_active Expired - Lifetime
- 1996-06-03 JP JP09501174A patent/JP3094305B2/ja not_active Expired - Fee Related
- 1996-06-03 CA CA002221255A patent/CA2221255C/en not_active Expired - Lifetime
- 1996-06-03 WO PCT/US1996/008642 patent/WO1996040094A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US5561163A (en) | 1996-10-01 |
| ES2194104T3 (es) | 2003-11-16 |
| DE69626816D1 (de) | 2003-04-24 |
| EP0831798B1 (de) | 2003-03-19 |
| JP3094305B2 (ja) | 2000-10-03 |
| AU5977296A (en) | 1996-12-30 |
| WO1996040094A1 (en) | 1996-12-19 |
| JPH10510843A (ja) | 1998-10-20 |
| EP0831798A1 (de) | 1998-04-01 |
| DE69626816T2 (de) | 2004-02-05 |
| CA2221255A1 (en) | 1996-12-19 |
| CA2221255C (en) | 2005-11-08 |
| AU693704B2 (en) | 1998-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |