ATE234643T1 - Biologische klebstoffzusammensetzung und verfahren zum fördern der haftung zwischen flächengewebe - Google Patents
Biologische klebstoffzusammensetzung und verfahren zum fördern der haftung zwischen flächengewebeInfo
- Publication number
- ATE234643T1 ATE234643T1 AT94919328T AT94919328T ATE234643T1 AT E234643 T1 ATE234643 T1 AT E234643T1 AT 94919328 T AT94919328 T AT 94919328T AT 94919328 T AT94919328 T AT 94919328T AT E234643 T1 ATE234643 T1 AT E234643T1
- Authority
- AT
- Austria
- Prior art keywords
- adhesive composition
- biological adhesive
- tissue
- promoting adhesion
- surface tissues
- Prior art date
Links
- 239000003364 biologic glue Substances 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title 1
- 108700039882 Protein Glutamine gamma Glutamyltransferase 2 Proteins 0.000 abstract 2
- 102100038095 Protein-glutamine gamma-glutamyltransferase 2 Human genes 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000008365 aqueous carrier Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 125000000404 glutamine group Chemical group N[C@@H](CCC(N)=O)C(=O)* 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/254—Enzymes, proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/834—Urine; urinary system
- Y10S530/835—Kidney
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/84—Bones; tendons; teeth; cartilage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/841—Muscles; heart
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/842—Skin; hair; nails; sebaceous glands; cerumen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/843—Digestive system
- Y10S530/846—Liver
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Surgery (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Adhesives Or Adhesive Processes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/071,528 US5549904A (en) | 1993-06-03 | 1993-06-03 | Biological adhesive composition and method of promoting adhesion between tissue surfaces |
| PCT/US1994/006208 WO1994028949A1 (en) | 1993-06-03 | 1994-06-03 | Biological adhesive composition and method of promoting adhesion between tissue surfaces |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234643T1 true ATE234643T1 (de) | 2003-04-15 |
Family
ID=22101910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94919328T ATE234643T1 (de) | 1993-06-03 | 1994-06-03 | Biologische klebstoffzusammensetzung und verfahren zum fördern der haftung zwischen flächengewebe |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5549904A (de) |
| EP (1) | EP0702572B1 (de) |
| JP (1) | JP3483255B2 (de) |
| AT (1) | ATE234643T1 (de) |
| AU (2) | AU7051194A (de) |
| CA (1) | CA2163250A1 (de) |
| DE (1) | DE69432300T2 (de) |
| ES (1) | ES2194869T3 (de) |
| TW (1) | TW404836B (de) |
| WO (1) | WO1994028949A1 (de) |
Families Citing this family (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5936035A (en) * | 1988-11-21 | 1999-08-10 | Cohesion Technologies, Inc. | Biocompatible adhesive compositions |
| US6117425A (en) | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
| US7208179B1 (en) * | 1990-11-27 | 2007-04-24 | The American National Red Cross | Methods for treating disease and forming a supplemented fibrin matrix |
| US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| JPH07328108A (ja) * | 1994-06-10 | 1995-12-19 | Ajinomoto Co Inc | 生体組織接着剤及び血液凝固剤 |
| US6010871A (en) * | 1994-09-29 | 2000-01-04 | Ajinomoto Co., Inc. | Modification of peptide and protein |
| US6458889B1 (en) | 1995-12-18 | 2002-10-01 | Cohesion Technologies, Inc. | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use |
| US6833408B2 (en) * | 1995-12-18 | 2004-12-21 | Cohesion Technologies, Inc. | Methods for tissue repair using adhesive materials |
| DK2111876T3 (da) | 1995-12-18 | 2011-12-12 | Angiodevice Internat Gmbh | Tværbundne polymerpræparater og fremgangsmåder til anvendelse deraf |
| US7883693B2 (en) | 1995-12-18 | 2011-02-08 | Angiodevice International Gmbh | Compositions and systems for forming crosslinked biomaterials and methods of preparation of use |
| CA2300194A1 (en) * | 1997-08-15 | 1999-02-25 | Children's Medical Center Corporation | Osteopontin coated surfaces and methods of use |
| US6114119A (en) * | 1997-08-29 | 2000-09-05 | Wisconsin Alumni Research Foundation | Transglutaminase and gene encoding same |
| US20030099620A1 (en) * | 1997-10-30 | 2003-05-29 | The General Hospital Corporation | Bonding of cartilaginous matrices using isolated chondrocytes |
| DE69831589T2 (de) * | 1997-10-30 | 2006-06-22 | The General Hospital Corp., Boston | Zusammenfügung von knorpelmatrizen unter verwendung isolierter chondrozyten |
| US6190896B1 (en) | 1997-11-14 | 2001-02-20 | Bassam M. Fraij | Active human cellular transglutaminase |
| EP1066051A4 (de) * | 1998-03-26 | 2002-05-02 | Gen Hospital Corp | Sciellin und seine verwendungen |
| US20020022588A1 (en) * | 1998-06-23 | 2002-02-21 | James Wilkie | Methods and compositions for sealing tissue leaks |
| US6190815B1 (en) * | 1998-08-11 | 2001-02-20 | Xerox Corporation | Toner compositions |
| US7241730B2 (en) * | 1998-08-27 | 2007-07-10 | Universitat Zurich | Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides |
| US6197061B1 (en) | 1999-03-01 | 2001-03-06 | Koichi Masuda | In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage |
| US6463335B1 (en) | 1999-10-04 | 2002-10-08 | Medtronic, Inc. | Temporary medical electrical lead having electrode mounting pad with biodegradable adhesive |
| JP2003520830A (ja) | 2000-01-25 | 2003-07-08 | エドワーズ ライフサイエンシーズ コーポレイション | 再狭窄および吻合内膜過形成処置のための送達系 |
| GB0011356D0 (en) * | 2000-05-12 | 2000-06-28 | Univ Nottingham Trent | Medical implant materials |
| US6685626B2 (en) | 2001-02-02 | 2004-02-03 | Regeneration Technologies, Inc. | Compositions, devices, methods, and kits for induction of adhesions |
| US20060094112A1 (en) * | 2001-03-07 | 2006-05-04 | Omotunde Babalola | Biological scaffold |
| ATE502660T1 (de) * | 2001-07-16 | 2011-04-15 | Depuy Products Inc | Poröses freisetzungsgerüst und verfahren |
| US8815793B2 (en) * | 2001-07-20 | 2014-08-26 | Northwestern University | Polymeric compositions and related methods of use |
| US7618937B2 (en) * | 2001-07-20 | 2009-11-17 | Northwestern University | Peptidomimetic polymers for antifouling surfaces |
| US7858679B2 (en) * | 2001-07-20 | 2010-12-28 | Northwestern University | Polymeric compositions and related methods of use |
| EP1435980A4 (de) * | 2001-09-15 | 2006-06-07 | Univ California | Stratifiziertes knorpelgewebe und verfahren zu seiner hestellung |
| US20030165473A1 (en) * | 2001-11-09 | 2003-09-04 | Rush-Presbyterian-St. Luke's Medical Center | Engineered intervertebral disc tissue |
| RU2203072C1 (ru) * | 2001-12-29 | 2003-04-27 | Челябинский государственный институт лазерной хирургии | Способ приготовления суспензии фетальных клеток, предназначенных для трансплантации при хронических заболеваниях печени |
| ES2223227B1 (es) | 2002-05-31 | 2006-04-16 | Consejo Sup. Investig. Cientificas | Secuencia de nucleotidos de maiz codificante de una proteina con actividad transglutaminasa, y su uso. |
| US8911831B2 (en) * | 2002-07-19 | 2014-12-16 | Northwestern University | Surface independent, surface-modifying, multifunctional coatings and applications thereof |
| US7163545B2 (en) * | 2002-07-29 | 2007-01-16 | Mayo Foundation For Medical Education And Research | Spinal cord surgical implant |
| US7208171B2 (en) * | 2002-10-31 | 2007-04-24 | Northwestern University | Injectable and bioadhesive polymeric hydrogels as well as related methods of enzymatic preparation |
| ATE457716T1 (de) * | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| CA2511486A1 (en) * | 2002-12-30 | 2004-07-22 | Angiotech International Ag | Tissue reactive compounds and compositions and uses thereof |
| JP2004283371A (ja) * | 2003-03-20 | 2004-10-14 | Nagoya Industrial Science Research Inst | 医用材料 |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US7101396B2 (en) | 2003-10-06 | 2006-09-05 | 3F Therapeutics, Inc. | Minimally invasive valve replacement system |
| EP1684671B1 (de) | 2003-10-06 | 2020-09-30 | Medtronic 3F Therapeutics, Inc. | Minimalinvasives klappenersatzsystem |
| ES2404682T3 (es) | 2003-12-11 | 2013-05-28 | Isto Technologies Inc. | Sistema de cartílago particulado |
| CN104174071A (zh) | 2004-04-28 | 2014-12-03 | 安希奥设备国际有限责任公司 | 用于形成交联生物材料的组合物和系统及关联的制备方法与用途 |
| WO2005122870A2 (en) | 2004-06-14 | 2005-12-29 | Pneumrx, Inc. | Lung access device |
| US7553810B2 (en) * | 2004-06-16 | 2009-06-30 | Pneumrx, Inc. | Lung volume reduction using glue composition |
| US20050281799A1 (en) | 2004-06-16 | 2005-12-22 | Glen Gong | Targeting damaged lung tissue using compositions |
| US20050281739A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Imaging damaged lung tissue using compositions |
| US7608579B2 (en) * | 2004-06-16 | 2009-10-27 | Pneumrx, Inc. | Lung volume reduction using glue compositions |
| US7678767B2 (en) | 2004-06-16 | 2010-03-16 | Pneumrx, Inc. | Glue compositions for lung volume reduction |
| US20050288702A1 (en) | 2004-06-16 | 2005-12-29 | Mcgurk Erin | Intra-bronchial lung volume reduction system |
| US20050281798A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Targeting sites of damaged lung tissue using composition |
| US20050281740A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Imaging damaged lung tissue |
| US20050288796A1 (en) * | 2004-06-23 | 2005-12-29 | Hani Awad | Native soft tissue matrix for therapeutic applications |
| WO2006014567A2 (en) | 2004-07-08 | 2006-02-09 | Pneumrx, Inc. | Pleural effusion treatment device, method and material |
| US7766891B2 (en) | 2004-07-08 | 2010-08-03 | Pneumrx, Inc. | Lung device with sealing features |
| CA2581093C (en) | 2004-09-17 | 2014-11-18 | Angiotech Biomaterials Corporation | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use |
| US20090319045A1 (en) | 2004-10-12 | 2009-12-24 | Truncale Katherine G | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| WO2006050213A2 (en) * | 2004-10-29 | 2006-05-11 | Michalow Alexander E | Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway |
| JP4874259B2 (ja) | 2004-11-23 | 2012-02-15 | ヌームアールエックス・インコーポレーテッド | 標的部位にアクセスするための操縦可能な装置 |
| US7815926B2 (en) * | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
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| US8921109B2 (en) | 2005-09-19 | 2014-12-30 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| US7732539B2 (en) * | 2006-02-16 | 2010-06-08 | National Science Foundation | Modified acrylic block copolymers for hydrogels and pressure sensitive wet adhesives |
| US9402633B2 (en) | 2006-03-13 | 2016-08-02 | Pneumrx, Inc. | Torque alleviating intra-airway lung volume reduction compressive implant structures |
| US8157837B2 (en) | 2006-03-13 | 2012-04-17 | Pneumrx, Inc. | Minimally invasive lung volume reduction device and method |
| US8888800B2 (en) | 2006-03-13 | 2014-11-18 | Pneumrx, Inc. | Lung volume reduction devices, methods, and systems |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2949407A1 (de) * | 1979-12-07 | 1981-06-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur gewinnung von (alpha) -2-sb-glykoprotein |
| DE3113986A1 (de) * | 1981-04-07 | 1982-10-21 | Robert Bosch Gmbh, 7000 Stuttgart | Vorrichtung zur regelung der leerlaufdrehzahl einer brennkraftmaschine |
| US4582794A (en) * | 1982-09-15 | 1986-04-15 | The University Of Arizona Foundation | Method of determining polyamine content of biological fluids |
| US4728643A (en) * | 1984-11-02 | 1988-03-01 | The General Hospital Corporation | Method of treating psoriasis |
| US5037816A (en) * | 1984-11-02 | 1991-08-06 | The General Hospital Corporation | Method of treating psoriasis |
| WO1989001512A1 (en) * | 1987-08-17 | 1989-02-23 | The Liposome Company, Inc. | A sponge enzyme having transglutaminase-like activity |
| US4968713A (en) * | 1989-07-31 | 1990-11-06 | Merck & Co., Inc. | Certain imidazole compounds as transglutaminase inhibitors |
| AU1268192A (en) * | 1991-01-04 | 1992-08-17 | Board Of Regents, The University Of Texas System | Cloning and expression of tissue transglutaminases |
| US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
| US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
-
1993
- 1993-06-03 US US08/071,528 patent/US5549904A/en not_active Expired - Lifetime
-
1994
- 1994-06-03 AU AU70511/94A patent/AU7051194A/en not_active Abandoned
- 1994-06-03 AT AT94919328T patent/ATE234643T1/de not_active IP Right Cessation
- 1994-06-03 JP JP50193595A patent/JP3483255B2/ja not_active Expired - Fee Related
- 1994-06-03 DE DE69432300T patent/DE69432300T2/de not_active Expired - Fee Related
- 1994-06-03 WO PCT/US1994/006208 patent/WO1994028949A1/en not_active Ceased
- 1994-06-03 ES ES94919328T patent/ES2194869T3/es not_active Expired - Lifetime
- 1994-06-03 CA CA002163250A patent/CA2163250A1/en not_active Abandoned
- 1994-06-03 EP EP94919328A patent/EP0702572B1/de not_active Expired - Lifetime
- 1994-06-06 TW TW083105136A patent/TW404836B/zh not_active IP Right Cessation
-
1996
- 1996-01-29 US US08/592,921 patent/US5736132A/en not_active Expired - Lifetime
-
1998
- 1998-09-01 AU AU83055/98A patent/AU8305598A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08510943A (ja) | 1996-11-19 |
| TW404836B (en) | 2000-09-11 |
| CA2163250A1 (en) | 1994-12-22 |
| AU8305598A (en) | 1999-04-29 |
| EP0702572B1 (de) | 2003-03-19 |
| JP3483255B2 (ja) | 2004-01-06 |
| US5549904A (en) | 1996-08-27 |
| ES2194869T3 (es) | 2003-12-01 |
| WO1994028949A1 (en) | 1994-12-22 |
| DE69432300T2 (de) | 2004-02-12 |
| EP0702572A1 (de) | 1996-03-27 |
| DE69432300D1 (de) | 2003-04-24 |
| AU7051194A (en) | 1995-01-03 |
| US5736132A (en) | 1998-04-07 |
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