ATE235681T1 - Konvexes klebefilmsystem für laseranheftungs- mikrodissektionsanalyse - Google Patents

Konvexes klebefilmsystem für laseranheftungs- mikrodissektionsanalyse

Info

Publication number
ATE235681T1
ATE235681T1 AT98931631T AT98931631T ATE235681T1 AT E235681 T1 ATE235681 T1 AT E235681T1 AT 98931631 T AT98931631 T AT 98931631T AT 98931631 T AT98931631 T AT 98931631T AT E235681 T1 ATE235681 T1 AT E235681T1
Authority
AT
Austria
Prior art keywords
convex surface
selectively activated
activated
rod
tissue sample
Prior art date
Application number
AT98931631T
Other languages
English (en)
Inventor
Seth R National Inst Goldstein
Robert F Bonner
Paul D Smith
John Peterson
Thomas Pohida
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE235681T1 publication Critical patent/ATE235681T1/de

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/2833—Collecting samples on a sticky, tacky, adhesive surface
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/2833—Collecting samples on a sticky, tacky, adhesive surface
    • G01N2001/284—Collecting samples on a sticky, tacky, adhesive surface using local activation of adhesive, i.e. Laser Capture Microdissection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Microscoopes, Condenser (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AT98931631T 1997-06-27 1998-06-25 Konvexes klebefilmsystem für laseranheftungs- mikrodissektionsanalyse ATE235681T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/883,821 US6100051A (en) 1997-06-27 1997-06-27 Method utilizing convex geometry for laser capture microdissection
PCT/US1998/013318 WO1999000658A1 (en) 1997-06-27 1998-06-25 Convex geometry adhesive film system for laser capture microdissection

Publications (1)

Publication Number Publication Date
ATE235681T1 true ATE235681T1 (de) 2003-04-15

Family

ID=25383394

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98931631T ATE235681T1 (de) 1997-06-27 1998-06-25 Konvexes klebefilmsystem für laseranheftungs- mikrodissektionsanalyse

Country Status (8)

Country Link
US (2) US6100051A (de)
EP (1) EP0991929B1 (de)
JP (2) JP4070247B2 (de)
AT (1) ATE235681T1 (de)
AU (1) AU744131B2 (de)
CA (1) CA2294353C (de)
DE (1) DE69812625T2 (de)
WO (1) WO1999000658A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469779B2 (en) 1997-02-07 2002-10-22 Arcturus Engineering, Inc. Laser capture microdissection method and apparatus
US6495195B2 (en) 1997-02-14 2002-12-17 Arcturus Engineering, Inc. Broadband absorbing film for laser capture microdissection
US7075640B2 (en) 1997-10-01 2006-07-11 Arcturus Bioscience, Inc. Consumable for laser capture microdissection
CA2319589C (en) * 1998-02-03 2008-11-18 The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services Mechanical handling systems for laser capture microdissection
US6720191B1 (en) 1998-02-03 2004-04-13 The United States Of America As Represented By The Department Of Health And Human Services Mechanical handling systems for laser capture microdissection
CA2337900C (en) * 1998-07-30 2004-05-11 Robert F. Bonner Precision laser capture microdissection utilizing short pulse length
US6743601B1 (en) * 1998-12-10 2004-06-01 The United States Of America As Represented By The Department Of Health And Human Services Non-contact laser capture microdissection
DE69941724D1 (de) * 1998-12-10 2010-01-07 Us Gov Health & Human Serv Laseranheftungs-mikrodissektion mit zwei laserpulsen zum ausdehnen und zurückziehen einer schicht
US6528248B2 (en) 1999-04-29 2003-03-04 Arcturus Engineering, Inc. Processing technology for LCM samples
US6690470B1 (en) * 1999-11-04 2004-02-10 Arcturus Engineering, Inc. Automated laser capture microdissection
WO2001061311A1 (en) 2000-02-16 2001-08-23 Arcturus Engineering, Inc. Transfer film for laser microcapture
DE10015157A1 (de) * 2000-03-27 2001-10-18 P A L M Gmbh Verfahren zur Bearbeitung einer biologischen Masse und Steuersystem für eine Vorrichtung zur Bearbeitung einer biologischen Masse
DE10018251C2 (de) 2000-04-13 2003-08-14 Leica Microsystems Laserschneid-Vorrichtung mit Mikroskop
DE10043504C2 (de) * 2000-09-01 2002-07-04 Leica Microsystems Verfahren zur Laser-Mikrodissektion und Verwendung einer Vorrichtung zur Laser-Mikrodissektion
DE10043506C1 (de) * 2000-09-01 2001-12-06 Leica Microsystems Verfahren und Vorrichtung zur Laser-Mikrodissektion
TW558861B (en) * 2001-06-15 2003-10-21 Semiconductor Energy Lab Laser irradiation stage, laser irradiation optical system, laser irradiation apparatus, laser irradiation method, and method of manufacturing semiconductor device
JP4217398B2 (ja) 2001-09-12 2009-01-28 キヤノン株式会社 画像データ処理方法、画像データ処理装置、記憶媒体、及びプログラム
US8722357B2 (en) * 2001-11-05 2014-05-13 Life Technologies Corporation Automated microdissection instrument
US10156501B2 (en) 2001-11-05 2018-12-18 Life Technologies Corporation Automated microdissection instrument for determining a location of a laser beam projection on a worksurface area
US8715955B2 (en) * 2004-09-09 2014-05-06 Life Technologies Corporation Laser microdissection apparatus and method
US7264966B2 (en) * 2002-01-23 2007-09-04 Olympus Optical Co., Ltd. Method of isolating cell or sample to be analyzed in cell
US6813008B2 (en) * 2002-06-10 2004-11-02 Palantyr Research, Llc Microdissection optical system
JP2004170930A (ja) * 2002-10-31 2004-06-17 Olympus Corp マイクロダイセクション装置および方法
EP1890126B1 (de) * 2006-08-11 2017-10-04 Molecular Machines & Industries AG Verfahren und Vorrichtung zum Schneiden und Sammeln von Dissektaten
EP1887340A1 (de) * 2006-08-11 2008-02-13 Molecular Machines & Industries AG Verfahren und Vorrichtung zum Schneiden und Sammeln von Dissektaten
DE102006038335A1 (de) * 2006-08-15 2008-02-21 Böcking, Alfred, Prof. Dr. med. Verfahren zur Zellanalyse
DE102006045620B4 (de) 2006-09-25 2009-10-29 Roland Dr. Kilper Vorrichtung und Verfahren für Aufnahme, Transport und Ablage mikroskopischer Proben
US8744163B2 (en) * 2010-02-09 2014-06-03 International Genomics Consortium System and method for laser dissection
CA2860338C (en) 2012-01-06 2022-08-02 Viomics, Inc. System and method of detecting rnas altered by cancer in peripheral blood
EP2817609B1 (de) * 2012-02-26 2021-04-07 Caliber Imaging & Diagnostics Inc. Gewebeprobentisch für optisches gewebeschnittmikroskop
CN105378449B (zh) * 2012-12-17 2019-02-05 胡文聪 取样组件、显微镜模块及显微镜装置
TW201728955A (zh) * 2016-02-05 2017-08-16 億觀生物科技股份有限公司 光學觀測裝置
TWI829197B (zh) * 2016-05-20 2024-01-11 美商瑞弗股份有限公司 奈米尺度計量系統
DE102019102852B3 (de) * 2019-02-05 2020-07-02 Leica Microsystems Cms Gmbh Verfahren zur Lasermikrodissektion, Lasermikrodissektionssystem und Computerprogramm

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1965861A (en) * 1933-04-15 1934-07-10 Reba S Schneider Skin conditioner
US4334844A (en) * 1979-12-05 1982-06-15 Tokyo Metropolitan Government Replica film of specimen for electron microscopy apparatus
US4629687A (en) 1982-07-29 1986-12-16 Board Of Trustees Of Michigan State University Positive selection sorting of cells
US4624915A (en) 1982-07-29 1986-11-25 Board Of Trustees Of Michigan State University Positive selection sorting of cells
EP0188273B1 (de) * 1985-01-14 1991-08-28 Sumitomo Electric Industries Limited Endoskop mit Lichtleitern
US5281517A (en) * 1985-11-04 1994-01-25 Cell Analysis Systems, Inc. Methods for immunoploidy analysis
US5084005A (en) * 1988-07-13 1992-01-28 Becton, Dickinson And Company Swab for collection of biological samples
US5202230A (en) * 1990-09-07 1993-04-13 Kamentsky Louis A Methods of detecting cut cells in a tissue section
DE4029326C1 (de) * 1990-09-15 1992-03-05 Viktor Dipl.-Ing. 5900 Siegen De Schatz
US5665582A (en) * 1990-10-29 1997-09-09 Dekalb Genetics Corp. Isolation of biological materials
US5817462A (en) * 1995-02-21 1998-10-06 Applied Spectral Imaging Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding
JP3067347B2 (ja) * 1991-10-30 2000-07-17 株式会社島津製作所 ゲル状ビーズの選別装置
US5843644A (en) * 1994-03-01 1998-12-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Isolation of cellular material under microscopic visualization using an adhesive/extraction reagent tipped probe
US5843657A (en) * 1994-03-01 1998-12-01 The United States Of America As Represented By The Department Of Health And Human Services Isolation of cellular material under microscopic visualization
US6060288A (en) * 1994-08-03 2000-05-09 Mosaic Technologies Method for performing amplification of nucleic acid on supports
US5723290A (en) * 1994-11-03 1998-03-03 Trustees Of The University Of Pennsylvania Methods for profiling mRNA expression in neurites
US6174424B1 (en) * 1995-11-20 2001-01-16 Cirrex Corp. Couplers for optical fibers
US5759781A (en) * 1995-12-22 1998-06-02 Yale University Multiparametric fluorescence in situ hybridization
DE69733650T2 (de) * 1996-03-01 2006-04-20 Beckman Coulter, Inc., Fullerton System zum simultanen Durchführen einer Vielzahl von Ligandenbindungs-Untersuchungen
CA2267454A1 (en) * 1996-09-30 1998-04-09 John O. Outwater Method and apparatus for determining a contact area between a probe and a specimen
US5859699A (en) * 1997-02-07 1999-01-12 Arcturus Engineering, Inc. Laser capture microdissection analysis vessel
DE19714475C1 (de) * 1997-04-08 1998-12-17 Wavelight Laser Technologie Gm Vorrichtung für das Entfernen von Körpersubstanzen
US5994149A (en) * 1997-10-01 1999-11-30 Leonard Bloom Rapid test employing an adhesive slide
US6251688B1 (en) * 1998-03-20 2001-06-26 Ia, Inc. Method and apparatus for measurement of binding between a protein and a nucleotide
US6231597B1 (en) * 1999-02-16 2001-05-15 Mark E. Deem Apparatus and methods for selectively stenting a portion of a vessel wall

Also Published As

Publication number Publication date
CA2294353C (en) 2008-04-08
AU744131B2 (en) 2002-02-14
DE69812625D1 (de) 2003-04-30
DE69812625T2 (de) 2004-03-25
EP0991929B1 (de) 2003-03-26
JP2002503345A (ja) 2002-01-29
EP0991929A1 (de) 2000-04-12
WO1999000658A1 (en) 1999-01-07
AU8170498A (en) 1999-01-19
JP2008076411A (ja) 2008-04-03
CA2294353A1 (en) 1999-01-07
US6100051A (en) 2000-08-08
US6783734B1 (en) 2004-08-31
JP4070247B2 (ja) 2008-04-02

Similar Documents

Publication Publication Date Title
ATE235681T1 (de) Konvexes klebefilmsystem für laseranheftungs- mikrodissektionsanalyse
JP4639022B2 (ja) 生物学的材料層の一部を単離する方法
CA2259171C (en) Microscope slide with removable layer and method
ATE364895T1 (de) Verfahren zur präparation einer probe für elektronenmikroskopische untersuchungen, sowie dabei verwendete probenträger und transporthalter
DE69005270D1 (de) Verfahren zur optischen analyse.
EP1278056A4 (de) Sonde für ein abtastmikroskop, hergestellt durch bearbeitung mit fokussiertem ionenstrahl
WO2002087792A8 (en) Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles
AU6426099A (en) Collection device for biological samples and methods of use
CA2045172A1 (en) Dual color camera microscope and methodology for cell staining and analysis
ATE530633T1 (de) Verfahren und vorrichtung zur bildung von biologischem zellmaterial
DE68921634D1 (de) Platine zur schnellen analyse und indexierung von filtern und anderen objektträgern unter einem mikroskop mit zugehörigen analyseverfahren.
ATE51299T1 (de) Verfahren und vorrichtung zum entnehmen einer bestimmten menge plasma aus einer blutprobe fuer die analyse.
ATE258683T1 (de) Verfahren zur durchführung einer speichelanalyse
DE69324614D1 (de) Mehrweg-Objektträgeranordnung zur Verwendung bei mikroskopischen Untersuchungen
JPWO2013077337A1 (ja) 組織分割装置、細胞分取装置、細胞分取システム、組織表示システム、基板、伸展部材、組織分割方法および細胞分取方法
Henry A method for obtaining ribbons of serial sections of plastic embedded specimens
DK1410014T3 (da) Fremgangsmåde til identifikation af pröver fra et pattedyr samt kit til udövelse af fremgangsmåden
DE60121919D1 (de) Verfahren und vorrichtung zur vorbereitung von zellproben
DK0724619T3 (da) Rengøringsopløsning for automatiske analyseapparater
Bradley A simple adaptation of the carbon replica technique for the examination of selected areas in the electron microscope
Wouters et al. Combined light microscope and scanning electron microscope, a new instrument for cell biology
CN216117641U (zh) 一种松材线虫快速检测试纸
US5683915A (en) Sample deposition device and method
JP2002022625A (ja) マイクロサンプリングシステム及びマイクロナイフ
Peat Comparative light microscopy, scanning electron microscopy and transmission electron microscopy of selected organic walled microfossils

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties