ATE237574T1 - Als antioxydanten verwendbare substituierte phenole und thiophenole - Google Patents

Als antioxydanten verwendbare substituierte phenole und thiophenole

Info

Publication number: ATE237574T1
Authority: AT; Austria
Prior art keywords: thiophenols; antioxidants; usable; substituted phenols; phenols
Prior art date: 1996-11-20

Application number

AT97910819T

Other languages

English (en)

Inventor

Roger A Parker

Paul S Wright

Steven J Busch

Kim S Chen

Mark Yates

Original Assignee

Aventis Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-20

Filing date

1997-10-07

Publication date

2003-05-15

1997-10-07 Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE237574T1 publication Critical patent/ATE237574T1/de

Links

239000003963 antioxidant agent Substances 0.000 title 1
150000002989 phenols Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
- C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Immunology (AREA)
Hematology (AREA)
Rheumatology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Emergency Medicine (AREA)
Transplantation (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Anti-Oxidant Or Stabilizer Compositions (AREA)

AT97910819T 1996-11-20 1997-10-07 Als antioxydanten verwendbare substituierte phenole und thiophenole ATE237574T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US75552896A	1996-11-20	1996-11-20
PCT/US1997/018055 WO1998022418A1 (en)	1996-11-20	1997-10-07	Substituted phenols and thiophenols useful as antioxidant agents

Publications (1)

Publication Number	Publication Date
ATE237574T1 true ATE237574T1 (de)	2003-05-15

Family

ID=25039544

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97910819T ATE237574T1 (de)	1996-11-20	1997-10-07	Als antioxydanten verwendbare substituierte phenole und thiophenole

Country Status (21)

Country	Link
EP (1)	EP0942896B1 (de)
JP (2)	JP4267705B2 (de)
KR (2)	KR100698995B1 (de)
CN (1)	CN1168693C (de)
AR (1)	AR009429A1 (de)
AT (1)	ATE237574T1 (de)
AU (1)	AU734050B2 (de)
BR (1)	BR9713372A (de)
CA (1)	CA2271054C (de)
DE (1)	DE69721040T2 (de)
DK (1)	DK0942896T3 (de)
ES (1)	ES2191828T3 (de)
HU (1)	HUP9904244A3 (de)
IL (1)	IL129957A (de)
NO (1)	NO318039B1 (de)
NZ (1)	NZ335440A (de)
PT (1)	PT942896E (de)
SI (1)	SI0942896T1 (de)
TW (1)	TW508349B (de)
WO (1)	WO1998022418A1 (de)
ZA (1)	ZA9710315B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6670398B2 (en)	1997-05-14	2003-12-30	Atherogenics, Inc.	Compounds and methods for treating transplant rejection
EP1695959A1 (de) *	1997-05-14	2006-08-30	Atherogenics, Inc.	Verbindungen und Methoden zur Hemmung der VCAM-1 Expression
US6852878B2 (en)	1998-05-14	2005-02-08	Atherogenics, Inc.	Thioketals and thioethers for inhibiting the expression of VCAM-1
EA200800375A1 (ru)	1997-05-14	2008-06-30	Атеродженикс, Инк.	Соединения и способы ингибирования экспрессии vcam-1
US6020383A (en) *	1999-01-11	2000-02-01	Eastman Chemicals Company	Method for reducing blood cholesterol and/or blood triglycerides
WO2003039231A2 (en) *	2001-10-25	2003-05-15	Atherogenics, Inc.	Compounds and methods for treating transplant rejection
US7294737B2 (en)	2004-04-20	2007-11-13	Atherogenics, Inc.	Process of preparing esters and ethers of probucol and derivatives thereof
KR100725582B1 (ko)	2004-06-29	2007-06-08	주식회사 동부하이텍	식물병원균의 생장억제활성을 갖는 알킬페놀 유도체
EP1827406B1 (de) *	2004-12-22	2010-07-28	Basf Se	Mittel gegen radikale
JP2010522762A (ja)	2007-03-26	2010-07-08	サルトリア・フアーマシユーテイカルズ・エル・エル・シー	糖尿病の治療のための方法及びプロブコール誘導体の組成物
KR101420083B1 (ko) *	2012-04-04	2014-07-15	이화여자대학교 산학협력단	Ｕｃｈ－ｌ１ 저해 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 ｕｃｈ－ｌ１ 관련 질환의 예방 또는 치료용 약학적 조성물
WO2014185561A1 (ko) *	2013-05-13	2014-11-20	이화여자대학교 산학협력단	신규한 화합물 또는 이의 약학적으로 허용 가능한 염 및 이를 유효성분으로 함유하는 ｕｃｈ－ｌ１ 관련 질환의 예방 또는 치료용 약학적 조성물
WO2016170704A1 (ja) *	2015-04-23	2016-10-27	株式会社日本ハイポックス	慢性呼吸器疾患治療剤及び心臓の線維化抑制組成物
CN121108026B (zh) *	2025-11-13	2026-02-10	江西众和化工有限公司	三氟乙基苯硫醚类化合物、农药组合物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57176038A (en) *	1981-04-21	1982-10-29	Fuji Photo Film Co Ltd	Silver halide color photographic material
CA2050514A1 (en) *	1990-09-14	1992-03-15	Bradley C. Pearce	Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia
DE4109627A1 (de) *	1991-03-23	1992-09-24	Boehringer Mannheim Gmbh	Neue phenolether, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
CA2096496A1 (en) *	1992-05-29	1993-11-30	Bradley C. Pearce	Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia
DE69217221T2 (de) *	1992-09-18	1997-05-15	Nippon Hypox Lab Inc	Hydrochinonderivate und diese enthaltende Antioxydantien sowie Tumorinhibitoren
TW393475B (en) *	1992-10-16	2000-06-11	Chugai Pharmaceutical Co Ltd	4-alkoxyl-2,6-di-t-butyl phenol derivatives
JP3050733B2 (ja) *	1992-10-16	2000-06-12	中外製薬株式会社	４−アルコキシ−２，６−ジ−ｔ−ブチルフェノール誘導体

1997
- 1997-10-07 EP EP97910819A patent/EP0942896B1/de not_active Expired - Lifetime
- 1997-10-07 KR KR1019997004402A patent/KR100698995B1/ko not_active Expired - Fee Related
- 1997-10-07 CA CA002271054A patent/CA2271054C/en not_active Expired - Fee Related
- 1997-10-07 PT PT97910819T patent/PT942896E/pt unknown
- 1997-10-07 AT AT97910819T patent/ATE237574T1/de not_active IP Right Cessation
- 1997-10-07 AU AU48098/97A patent/AU734050B2/en not_active Ceased
- 1997-10-07 SI SI9730517T patent/SI0942896T1/xx unknown
- 1997-10-07 IL IL12995797A patent/IL129957A/xx not_active IP Right Cessation
- 1997-10-07 DE DE69721040T patent/DE69721040T2/de not_active Expired - Lifetime
- 1997-10-07 HU HU9904244A patent/HUP9904244A3/hu unknown
- 1997-10-07 JP JP52363998A patent/JP4267705B2/ja not_active Expired - Fee Related
- 1997-10-07 BR BR9713372A patent/BR9713372A/pt not_active IP Right Cessation
- 1997-10-07 NZ NZ335440A patent/NZ335440A/en unknown
- 1997-10-07 DK DK97910819T patent/DK0942896T3/da active
- 1997-10-07 ES ES97910819T patent/ES2191828T3/es not_active Expired - Lifetime
- 1997-10-07 WO PCT/US1997/018055 patent/WO1998022418A1/en not_active Ceased
- 1997-10-07 CN CNB971999104A patent/CN1168693C/zh not_active Expired - Fee Related
- 1997-10-07 KR KR1020067001270A patent/KR100648118B1/ko not_active Expired - Fee Related
- 1997-11-14 ZA ZA9710315A patent/ZA9710315B/xx unknown
- 1997-11-15 TW TW086117094A patent/TW508349B/zh not_active IP Right Cessation
- 1997-11-17 AR ARP970105361A patent/AR009429A1/es not_active Application Discontinuation
1999
- 1999-05-19 NO NO19992390A patent/NO318039B1/no not_active IP Right Cessation
2008
- 2008-11-19 JP JP2008295012A patent/JP2009132710A/ja active Pending

Also Published As

Publication number	Publication date
KR100648118B1 (ko)	2006-11-28
SI0942896T1 (en)	2003-08-31
BR9713372A (pt)	2000-03-21
EP0942896A1 (de)	1999-09-22
JP2009132710A (ja)	2009-06-18
CA2271054C (en)	2005-12-13
AU4809897A (en)	1998-06-10
CN1237955A (zh)	1999-12-08
IL129957A0 (en)	2000-02-29
ZA9710315B (en)	1998-05-20
PT942896E (pt)	2003-07-31
NO318039B1 (no)	2005-01-24
JP2001504483A (ja)	2001-04-03
HUP9904244A3 (en)	2002-07-29
IL129957A (en)	2005-06-19
TW508349B (en)	2002-11-01
CN1168693C (zh)	2004-09-29
NO992390L (no)	1999-07-16
KR100698995B1 (ko)	2007-03-26
DE69721040D1 (de)	2003-05-22
CA2271054A1 (en)	1998-05-28
NO992390D0 (no)	1999-05-19
HK1021970A1 (en)	2000-07-21
EP0942896B1 (de)	2003-04-16
NZ335440A (en)	2001-07-27
AU734050B2 (en)	2001-05-31
HUP9904244A2 (hu)	2000-09-28
KR20000057135A (ko)	2000-09-15
KR20060016839A (ko)	2006-02-22
ES2191828T3 (es)	2003-09-16
WO1998022418A1 (en)	1998-05-28
DK0942896T3 (da)	2003-07-28
DE69721040T2 (de)	2003-10-16
AR009429A1 (es)	2000-04-12
JP4267705B2 (ja)	2009-05-27

Legal Events

Date

Code

Title

Description

2003-09-15

UEP

Publication of translation of european patent specification

Ref document number: 0942896

Country of ref document: EP

2010-07-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69712238D1 (de)	2002-06-06	Schalter und Dämpfunsglied
DE69726844D1 (de)	2004-01-29	Künstliche zwischenwirbelscheibe
BR9711781A (pt)	1999-08-24	Mancal
ID18085A (id)	1998-02-26	Popok sekali pakai jenis tarikan
DE69739146D1 (de)	2009-01-15	Absorbierende zusammensetzung
DE69810660D1 (de)	2003-02-13	Abhitzedampferzeuger und betriebsverfahren dafür
ID17427A (id)	1997-12-24	Popok sekali pakai
ID17346A (id)	1997-12-18	Popok sekali pakai
ID18096A (id)	1998-02-26	Popok sekali pakai
ID17545A (id)	1998-01-08	Popok sekali pakai
ID17591A (id)	1998-01-15	Popok sekali pakai
DE59711118D1 (de)	2004-01-22	Spickeln, Zunehmen und Mindern
ID18374A (id)	1998-04-02	Popok sekali pakai
NO982414D0 (no)	1998-05-27	Ny kombinasjon
ID17571A (id)	1998-01-08	Popok sekali pakai
ID18359A (id)	1998-04-02	Komposisi mikrokapsul
ID16110A (id)	1997-09-04	Sakelar geser
DE59806095D1 (de)	2002-12-05	Mähscheibe und Mähwerk
DK0942896T3 (da)	2003-07-28	Substituerede phenoler og thiophenoler velegnede som antioxidanter
BR9612583A (pt)	1999-07-20	Mancal de rolamento
ID16287A (id)	1997-09-18	Popok sekali pakai
NO962808D0 (no)	1996-07-03	Tobakkerstatning
DE59705744D1 (de)	2002-01-24	Aufschnittschneidemaschine
ATE235498T1 (de)	2003-04-15	Alkyl-4-silylheterocyclische phenole und thiophenole als antioxidansmittel
DE69602074D1 (de)	1999-05-20	Radioempfänger und Betriebsverfahren