ATE239785T1 - Funktionelle domänen der restriktionsendonukleasen aus -i(flavobakterium okeanokoites)(foki) - Google Patents
Funktionelle domänen der restriktionsendonukleasen aus -i(flavobakterium okeanokoites)(foki)Info
- Publication number
- ATE239785T1 ATE239785T1 AT94909526T AT94909526T ATE239785T1 AT E239785 T1 ATE239785 T1 AT E239785T1 AT 94909526 T AT94909526 T AT 94909526T AT 94909526 T AT94909526 T AT 94909526T AT E239785 T1 ATE239785 T1 AT E239785T1
- Authority
- AT
- Austria
- Prior art keywords
- foki
- recognition
- present
- domain
- relates
- Prior art date
Links
- 108091008146 restriction endonucleases Proteins 0.000 title abstract 5
- 241000589579 Planomicrobium okeanokoites Species 0.000 title 1
- 238000003776 cleavage reaction Methods 0.000 abstract 3
- 230000007017 scission Effects 0.000 abstract 3
- 101710163270 Nuclease Proteins 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 210000004900 c-terminal fragment Anatomy 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 108010026638 endodeoxyribonuclease FokI Proteins 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 210000004898 n-terminal fragment Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1749393A | 1993-02-12 | 1993-02-12 | |
| PCT/US1994/001201 WO1994018313A1 (en) | 1993-02-12 | 1994-02-10 | Functional domains in flavobacterium okeanokoites (foki) restriction endonuclease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239785T1 true ATE239785T1 (de) | 2003-05-15 |
Family
ID=21782900
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03010009T ATE513037T1 (de) | 1993-02-12 | 1994-02-10 | Funktionelle domänen der restriktionsendonukleasen aus flavobakterium okeanokoites (foki) |
| AT94909526T ATE239785T1 (de) | 1993-02-12 | 1994-02-10 | Funktionelle domänen der restriktionsendonukleasen aus -i(flavobakterium okeanokoites)(foki) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03010009T ATE513037T1 (de) | 1993-02-12 | 1994-02-10 | Funktionelle domänen der restriktionsendonukleasen aus flavobakterium okeanokoites (foki) |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP0682699B1 (de) |
| JP (1) | JPH08510375A (de) |
| AT (2) | ATE513037T1 (de) |
| AU (1) | AU6234594A (de) |
| CA (1) | CA2154581C (de) |
| DE (1) | DE69432628T8 (de) |
| WO (1) | WO1994018313A1 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5436150A (en) * | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US8206965B2 (en) | 2002-03-15 | 2012-06-26 | Cellectis S.A. | Hybrid and single chain meganucleases and use thereof |
| WO2009095742A1 (en) | 2008-01-31 | 2009-08-06 | Cellectis | New i-crei derived single-chain meganuclease and uses thereof |
| WO2004067753A2 (en) | 2003-01-28 | 2004-08-12 | Cellectis | Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof. |
| CA2539439C (en) | 2003-09-19 | 2012-10-23 | Sangamo Biosciences, Inc. | Engineered zinc finger proteins for regulation of gene expression |
| DK2025756T3 (da) | 2003-11-18 | 2011-10-03 | Bayer Bioscience Nv | Forbedret målrettet DNA-indsætning i planter |
| CN101155921B (zh) | 2005-04-04 | 2013-02-06 | 拜尔作物科学公司 | 用于去除所选择dna序列的方法和手段 |
| US8367890B2 (en) | 2006-09-28 | 2013-02-05 | Bayer Cropscience N.V. | Methods and means for removal of a selected DNA sequence |
| US8765448B2 (en) | 2007-06-05 | 2014-07-01 | Bayer CropScience, N.V. | Methods and means for exact replacement of target DNA in eukaryotic organisms |
| DK2205749T3 (en) | 2007-09-27 | 2016-08-22 | Dow Agrosciences Llc | MODIFIED PROTEINS zinc finger, which target the 5-enolpyruvylshikimate-3-phosphate synthase genes |
| US20110239315A1 (en) | 2009-01-12 | 2011-09-29 | Ulla Bonas | Modular dna-binding domains and methods of use |
| EP2206723A1 (de) | 2009-01-12 | 2010-07-14 | Bonas, Ulla | Modulare DNA-bindende Domänen |
| EP3456826B1 (de) | 2009-12-10 | 2023-06-28 | Regents of the University of Minnesota | Tal-effektor-vermittelte dna-modifizierung |
| JP6208580B2 (ja) | 2010-05-17 | 2017-10-04 | サンガモ セラピューティクス, インコーポレイテッド | 新規のdna結合タンパク質及びその使用 |
| AU2011264074B2 (en) | 2010-06-09 | 2015-01-22 | Bayer Cropscience Nv | Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering |
| RU2639512C2 (ru) | 2010-06-09 | 2017-12-21 | Байер Кропсайенс Нв | Способы и средство модификации растительного генома в нуклеотидной последовательности, широко используемой в геномной инженерии растений |
| CN103597082B (zh) | 2011-06-06 | 2017-09-15 | 拜尔作物科学公司 | 用于在预选位点修饰植物基因组的方法和手段 |
| CN107287234A (zh) | 2011-08-22 | 2017-10-24 | 拜尔作物科学公司 | 修饰植物基因组的方法和手段 |
| US20140251317A1 (en) | 2011-10-12 | 2014-09-11 | Bayer Cropscience Ag | Plants with decreased activity of a starch dephosphorylating enzyme |
| US20140283819A1 (en) | 2011-10-12 | 2014-09-25 | Bayer Cropscience Ag | Plants with decreased activity of a starch dephosphorylating enzyme |
| US11518997B2 (en) | 2012-04-23 | 2022-12-06 | BASF Agricultural Solutions Seed US LLC | Targeted genome engineering in plants |
| RU2014153918A (ru) | 2012-06-12 | 2016-07-27 | Дженентек, Инк. | Способы и композиции для получения условно нокаутных аллелей |
| EP2861737B1 (de) | 2012-06-19 | 2019-04-17 | Regents Of The University Of Minnesota | Gen-targeting in pflanzen durch dns-viren |
| CN104968193B (zh) | 2012-11-01 | 2021-02-09 | 塞尔克蒂斯股份有限公司 | 用于生成治疗性蛋白质的植物 |
| US20140178561A1 (en) | 2012-12-21 | 2014-06-26 | Cellectis | Potatoes with reduced cold-induced sweetening |
| US10113162B2 (en) | 2013-03-15 | 2018-10-30 | Cellectis | Modifying soybean oil composition through targeted knockout of the FAD2-1A/1B genes |
| WO2014161821A1 (en) | 2013-04-02 | 2014-10-09 | Bayer Cropscience Nv | Targeted genome engineering in eukaryotes |
| EP2878667A1 (de) | 2013-11-29 | 2015-06-03 | Institut Pasteur | TAL-Effektormittel zur partiellen oder vollständigen Deletion von DNA-Tandem-Repeats |
| US9522936B2 (en) | 2014-04-24 | 2016-12-20 | Sangamo Biosciences, Inc. | Engineered transcription activator like effector (TALE) proteins |
| WO2015193858A1 (en) | 2014-06-20 | 2015-12-23 | Cellectis | Potatoes with reduced granule-bound starch synthase |
| CN107429241B (zh) | 2014-08-14 | 2025-10-24 | 百奥赛图(北京)医药科技股份有限公司 | Dna敲入系统 |
| EP3289080B1 (de) | 2015-04-30 | 2021-08-25 | The Trustees of Columbia University in the City of New York | Gentherapie für autosomal dominante erkrankungen |
| US10837024B2 (en) | 2015-09-17 | 2020-11-17 | Cellectis | Modifying messenger RNA stability in plant transformations |
| WO2017134601A1 (en) | 2016-02-02 | 2017-08-10 | Cellectis | Modifying soybean oil composition through targeted knockout of the fad3a/b/c genes |
| CN109415737A (zh) | 2016-05-25 | 2019-03-01 | 嘉吉公司 | 用于在植物中产生突变的工程化核酸酶 |
| EA201892624A1 (ru) | 2016-05-26 | 2019-06-28 | Нунхемс Б.В. | Растения, дающие бессемянные плоды |
| US20190225974A1 (en) | 2016-09-23 | 2019-07-25 | BASF Agricultural Solutions Seed US LLC | Targeted genome optimization in plants |
| WO2018144097A1 (en) | 2016-11-04 | 2018-08-09 | Akeagen Llc | Genetically modified non-human animals and methods for producing heavy chain-only antibodies |
| WO2018092072A1 (en) | 2016-11-16 | 2018-05-24 | Cellectis | Methods for altering amino acid content in plants through frameshift mutations |
| CA3060622A1 (en) | 2017-04-25 | 2018-11-01 | Cellectis | Alfalfa with reduced lignin composition |
| DK3501268T3 (da) | 2017-12-22 | 2021-11-08 | Kws Saat Se & Co Kgaa | Regenerering af planter i tilstedeværelse af histondeacetylase hæmmere |
| EP3508581A1 (de) | 2018-01-03 | 2019-07-10 | Kws Saat Se | Regenerierung von genetisch modifizierten pflanzen |
| US20200362366A1 (en) | 2018-01-12 | 2020-11-19 | Basf Se | Gene underlying the number of spikelets per spike qtl in wheat on chromosome 7a |
| JP2021519067A (ja) | 2018-03-23 | 2021-08-10 | ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | 常染色体優性疾患のための遺伝子編集 |
| EP3545756A1 (de) | 2018-03-28 | 2019-10-02 | KWS SAAT SE & Co. KGaA | Regeneration von pflanzen in gegenwart von inhibitoren der histonmethyltransferase ezh2 |
| ES3047057T3 (en) | 2018-05-09 | 2025-12-03 | Kws Saat Se & Co Kgaa | Gene for resistance to a pathogen of the genus heterodera |
| EP3807300A1 (de) | 2018-06-15 | 2021-04-21 | KWS SAAT SE & Co. KGaA | Verfahren zur verbesserung von genom-engineering und regeneration bei pflanzen |
| CA3103564A1 (en) | 2018-06-15 | 2019-12-19 | KWS SAAT SE & Co. KGaA | Methods for enhancing genome engineering efficiency |
| US12146142B2 (en) | 2018-06-15 | 2024-11-19 | KWS SAAT SE & Co. KGaA | Methods for improving genome engineering and regeneration in plant II |
| EP3806619A1 (de) | 2018-06-15 | 2021-04-21 | Nunhems B.V. | Kernlose wassermelonenpflanzen mit modifikationen in einem abc-transporter-gen |
| EP3623379A1 (de) | 2018-09-11 | 2020-03-18 | KWS SAAT SE & Co. KGaA | Gen zur modifizierung von rhizomania-virus (bnyvv)-resistenz |
| EP3906309A2 (de) | 2019-01-04 | 2021-11-10 | Cargill, Incorporated | Modifizierte nukleasen zur erzeugung von mutationen in pflanzen |
| US20220112511A1 (en) | 2019-01-29 | 2022-04-14 | The University Of Warwick | Methods for enhancing genome engineering efficiency |
| EP3708651A1 (de) | 2019-03-12 | 2020-09-16 | KWS SAAT SE & Co. KGaA | Verbesserung der pflanzenregeneration |
| EP3757219A1 (de) | 2019-06-28 | 2020-12-30 | KWS SAAT SE & Co. KGaA | Verbesserte pflanzenregeneration und -umwandlung unter verwendung des grf1-booster-gens |
| CN115335528A (zh) | 2019-11-12 | 2022-11-11 | 科沃施种子欧洲股份两合公司 | 孢囊线虫属病原体抗性基因 |
| CA3169128A1 (en) | 2020-02-28 | 2021-09-02 | Ling MENG | Immature inflorescence meristem editing |
| EP4019638A1 (de) | 2020-12-22 | 2022-06-29 | KWS SAAT SE & Co. KGaA | Förderung der regeneration und transformation in beta vulgaris |
| EP4019639A1 (de) | 2020-12-22 | 2022-06-29 | KWS SAAT SE & Co. KGaA | Förderung der regeneration und transformation in beta vulgaris |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0589958A4 (de) * | 1991-06-11 | 1995-04-26 | Gen Hospital Corp | Universelle ortsspezifische nuklease. |
-
1994
- 1994-02-10 AT AT03010009T patent/ATE513037T1/de not_active IP Right Cessation
- 1994-02-10 AT AT94909526T patent/ATE239785T1/de not_active IP Right Cessation
- 1994-02-10 EP EP94909526A patent/EP0682699B1/de not_active Revoked
- 1994-02-10 DE DE69432628T patent/DE69432628T8/de not_active Revoked
- 1994-02-10 JP JP6518193A patent/JPH08510375A/ja active Pending
- 1994-02-10 WO PCT/US1994/001201 patent/WO1994018313A1/en not_active Ceased
- 1994-02-10 CA CA002154581A patent/CA2154581C/en not_active Expired - Lifetime
- 1994-02-10 EP EP03010009A patent/EP1340812B1/de not_active Expired - Lifetime
- 1994-02-10 AU AU62345/94A patent/AU6234594A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994018313A1 (en) | 1994-08-18 |
| EP1340812B1 (de) | 2011-06-15 |
| JPH08510375A (ja) | 1996-11-05 |
| CA2154581A1 (en) | 1994-08-18 |
| EP1340812A3 (de) | 2004-01-28 |
| EP1340812A2 (de) | 2003-09-03 |
| DE69432628T8 (de) | 2004-07-08 |
| CA2154581C (en) | 2008-12-16 |
| EP0682699A1 (de) | 1995-11-22 |
| DE69432628T2 (de) | 2004-03-11 |
| ATE513037T1 (de) | 2011-07-15 |
| EP0682699A4 (de) | 1997-02-12 |
| EP0682699B1 (de) | 2003-05-07 |
| DE69432628D1 (de) | 2003-06-12 |
| AU6234594A (en) | 1994-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |