ATE240949T1 - Epoxysuccinamid-derivate oder ihre salze - Google Patents

Epoxysuccinamid-derivate oder ihre salze

Info

Publication number
ATE240949T1
ATE240949T1 AT98914078T AT98914078T ATE240949T1 AT E240949 T1 ATE240949 T1 AT E240949T1 AT 98914078 T AT98914078 T AT 98914078T AT 98914078 T AT98914078 T AT 98914078T AT E240949 T1 ATE240949 T1 AT E240949T1
Authority
AT
Austria
Prior art keywords
substituted
group
alkyl
salt
hydrogen atom
Prior art date
Application number
AT98914078T
Other languages
English (en)
Inventor
Tetsuji Asao
Tomohiro Yamashita
Yoshimitsu Suda
Shigeo Okajima
Yukio Tada
Nobuhiko Katsunuma
Shozo Yamada
Kazuhiko Shigeno
Atsuhiko Uemura
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE240949T1 publication Critical patent/ATE240949T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98914078T 1997-04-18 1998-04-17 Epoxysuccinamid-derivate oder ihre salze ATE240949T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10215197 1997-04-18
PCT/JP1998/001778 WO1998047887A1 (en) 1997-04-18 1998-04-17 Novel epoxysuccinamide derivatives or salts thereof

Publications (1)

Publication Number Publication Date
ATE240949T1 true ATE240949T1 (de) 2003-06-15

Family

ID=14319744

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98914078T ATE240949T1 (de) 1997-04-18 1998-04-17 Epoxysuccinamid-derivate oder ihre salze

Country Status (8)

Country Link
US (1) US6110967A (de)
EP (1) EP0921122B1 (de)
JP (1) JP3410476B2 (de)
AT (1) ATE240949T1 (de)
AU (1) AU727497B2 (de)
CA (1) CA2258354A1 (de)
DE (1) DE69814800T2 (de)
WO (1) WO1998047887A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6620844B2 (en) * 2001-02-14 2003-09-16 Newmillennium Pharmaceutical, Inc. Method for reducing blood insulin levels by reducing in vivo cathepsin L activity
US20040009891A1 (en) * 2001-02-14 2004-01-15 Newmillennium Pharmaceutical, Inc. Method and composition for treating obesity by targeting cathepsin
DK1474425T3 (da) * 2002-01-07 2006-09-25 Eisai Co Ltd Deazapuriner og anvendelser deraf
ITPD20050056A1 (it) 2005-03-02 2006-09-03 Fidia Farmaceutici Derivati ammidici del'acido ialuronico in osteoartrosi
WO2007038772A1 (en) * 2005-09-28 2007-04-05 American Life Science Pharmaceuticals Novel drugs for dementia
US8673904B2 (en) 2006-06-13 2014-03-18 The Board Of Trustees Of The Leland Stanford Junior University Epoxide inhibitors of cysteine proteases
US20100216875A1 (en) * 2006-12-20 2010-08-26 Gregory Hook Methods of treating alzheimer's disease
WO2008149971A1 (ja) 2007-06-08 2008-12-11 Kyoto University 脳動脈瘤の治療または予防薬
US20100331545A1 (en) 2007-10-24 2010-12-30 Nippon Chemiphar Co., Ltd. Regulator for signaling toll-like receptor, which comprises cathepsin inhibitor as active ingredient
CN101967209B (zh) * 2010-10-20 2012-11-07 南京大学 一种n-乙酰基乙二胺螯合树脂及其制备方法
JP6175078B2 (ja) 2012-02-01 2017-08-02 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク 新規のシステインプロテアーゼ阻害剤及びその使用
CN104211666B (zh) * 2013-05-31 2017-11-14 中国人民解放军军事医学科学院毒物药物研究所 2,3‑环氧丁二酰胺类化合物、其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556853A (en) * 1993-10-29 1996-09-17 Takeda Chemical Industries, Ltd. Epoxysuccinic acid derivatives
JPH08104683A (ja) * 1993-10-29 1996-04-23 Takeda Chem Ind Ltd エポキシコハク酸誘導体
JPH08104684A (ja) * 1994-05-31 1996-04-23 Takeda Chem Ind Ltd エポキシコハク酸関連化合物
US5679708A (en) * 1994-05-31 1997-10-21 Takeda Chemical Industries, Ltd. Epoxysuccinic acid derivatives, their production and use
JP3338452B2 (ja) * 1995-12-12 2002-10-28 大鵬薬品工業株式会社 エポキシコハク酸アミド誘導体又はその塩及びこれを含有する医薬

Also Published As

Publication number Publication date
AU6853798A (en) 1998-11-13
DE69814800D1 (de) 2003-06-26
DE69814800T2 (de) 2003-12-18
AU727497B2 (en) 2000-12-14
JP3410476B2 (ja) 2003-05-26
EP0921122A4 (de) 2001-06-13
EP0921122B1 (de) 2003-05-21
CA2258354A1 (en) 1998-10-29
EP0921122A1 (de) 1999-06-09
WO1998047887A1 (en) 1998-10-29
US6110967A (en) 2000-08-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties