ATE241383T1 - Behandlung von allergischen zuständen mit cystein-und serin-proteinase inhibitoren - Google Patents

Behandlung von allergischen zuständen mit cystein-und serin-proteinase inhibitoren

Info

Publication number: ATE241383T1
Authority: AT; Austria
Prior art keywords: treatment; cystein; proteinase inhibitors; serine proteinase; allergic conditions
Prior art date: 1997-12-11

Application number

AT98959056T

Other languages

English (en)

Inventor

David Ronald Garrod

Clive Robinson

Original Assignee

Univ Manchester

St Georges Hosp Medical School

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-11

Filing date

1998-12-11

Publication date

2003-06-15

1998-12-11 Application filed by Univ Manchester, St Georges Hosp Medical School filed Critical Univ Manchester

2003-06-15 Application granted granted Critical

2003-06-15 Publication of ATE241383T1 publication Critical patent/ATE241383T1/de

Links

239000003001 serine protease inhibitor Substances 0.000 title abstract 2
206010027654 Allergic conditions Diseases 0.000 title 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 title 1
239000013566 allergen Substances 0.000 abstract 2
210000004082 barrier epithelial cell Anatomy 0.000 abstract 2
230000004890 epithelial barrier function Effects 0.000 abstract 2
239000003112 inhibitor Substances 0.000 abstract 2
230000002265 prevention Effects 0.000 abstract 2
MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
102000005927 Cysteine Proteases Human genes 0.000 abstract 1
108010005843 Cysteine Proteases Proteins 0.000 abstract 1
MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
102000012479 Serine Proteases Human genes 0.000 abstract 1
108010022999 Serine Proteases Proteins 0.000 abstract 1
102000004142 Trypsin Human genes 0.000 abstract 1
108090000631 Trypsin Proteins 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
239000002852 cysteine proteinase inhibitor Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000012588 trypsin Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
Ophthalmology & Optometry (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Otolaryngology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT98959056T 1997-12-11 1998-12-11 Behandlung von allergischen zuständen mit cystein-und serin-proteinase inhibitoren ATE241383T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9726114.3A GB9726114D0 (en)	1997-12-11	1997-12-11	Prevention and/or treatment of allergic conditions
PCT/GB1998/003721 WO1999029339A2 (en)	1997-12-11	1998-12-11	Prevention and/or treatment of allergic conditions

Publications (1)

Publication Number	Publication Date
ATE241383T1 true ATE241383T1 (de)	2003-06-15

Family

ID=10823401

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98959056T ATE241383T1 (de)	1997-12-11	1998-12-11	Behandlung von allergischen zuständen mit cystein-und serin-proteinase inhibitoren

Country Status (13)

Country	Link
US (1)	US6440938B1 (de)
EP (1)	EP1032415B1 (de)
JP (2)	JP2001525374A (de)
AT (1)	ATE241383T1 (de)
AU (1)	AU747723C (de)
CA (1)	CA2313653C (de)
DE (1)	DE69815143T2 (de)
ES (1)	ES2200394T3 (de)
GB (1)	GB9726114D0 (de)
HR (1)	HRP20000450A2 (de)
HU (1)	HUP0100788A2 (de)
PT (1)	PT1032415E (de)
WO (1)	WO1999029339A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0125594D0 (en) *	2001-10-25	2001-12-19	Univ Sheffield	Inhibitors for inactivating allergens
EP3193906B1 (de) *	2014-09-18	2020-11-11	The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of Holy and Undiv. Trinity of Queen Elizabeth near Dublin	Verwendung von il-36 peptid inhibitoren zur behandlung und/oder reduktion von entzündungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5166134A (en) *	1986-12-24	1992-11-24	John Lezdey	Treatment of allergic rhinitis
US6034066A (en) *	1995-07-17	2000-03-07	Peptide Therapeutics Limited	Cysteine protease inhibitors for use in treatment of IGE mediated allergic diseases

1997
- 1997-12-11 GB GBGB9726114.3A patent/GB9726114D0/en not_active Ceased
1998
- 1998-12-11 PT PT98959056T patent/PT1032415E/pt unknown
- 1998-12-11 DE DE69815143T patent/DE69815143T2/de not_active Expired - Lifetime
- 1998-12-11 CA CA2313653A patent/CA2313653C/en not_active Expired - Fee Related
- 1998-12-11 US US09/581,075 patent/US6440938B1/en not_active Expired - Lifetime
- 1998-12-11 AT AT98959056T patent/ATE241383T1/de not_active IP Right Cessation
- 1998-12-11 AU AU14985/99A patent/AU747723C/en not_active Ceased
- 1998-12-11 HU HU0100788A patent/HUP0100788A2/hu unknown
- 1998-12-11 EP EP98959056A patent/EP1032415B1/de not_active Expired - Lifetime
- 1998-12-11 WO PCT/GB1998/003721 patent/WO1999029339A2/en not_active Ceased
- 1998-12-11 JP JP2000524008A patent/JP2001525374A/ja not_active Withdrawn
- 1998-12-11 HR HR20000450A patent/HRP20000450A2/hr not_active Application Discontinuation
- 1998-12-11 ES ES98959056T patent/ES2200394T3/es not_active Expired - Lifetime
2009
- 2009-12-25 JP JP2009295744A patent/JP2010155831A/ja active Pending

Also Published As

Publication number	Publication date
PT1032415E (pt)	2003-09-30
AU747723B2 (en)	2002-05-23
WO1999029339A2 (en)	1999-06-17
ES2200394T3 (es)	2004-03-01
US6440938B1 (en)	2002-08-27
HRP20000450A2 (en)	2001-06-30
DE69815143T2 (de)	2004-04-01
AU747723C (en)	2003-10-02
JP2001525374A (ja)	2001-12-11
GB9726114D0 (en)	1998-02-11
WO1999029339A3 (en)	1999-08-12
CA2313653A1 (en)	1999-06-17
CA2313653C (en)	2011-02-01
AU1498599A (en)	1999-06-28
EP1032415B1 (de)	2003-05-28
EP1032415A2 (de)	2000-09-06
DE69815143D1 (de)	2003-07-03
JP2010155831A (ja)	2010-07-15
HUP0100788A2 (hu)	2001-06-28

Legal Events

Date	Code	Title	Description
2003-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
TR199801151T2 (xx)	1998-08-21	Trombin inhibit�r� �n ila�lar.
DE69635447D1 (de)	2005-12-22	Plasma-kallikrein inhibitoren vom kunitz-typ
IS6069A (is)	2001-09-07	N-cýanómetýlamíð sem próteasalatar
TR199901191T2 (xx)	1999-12-21	Benzamidoaldehitlerin sistein proteaz� inhibit�r� olarak kullan�m�.
NO20005888D0 (no)	2000-11-21	Benzimidale derivater som mudulatorer av IgE
ATE520411T1 (de)	2011-09-15	Behandlung und prävention von lungenerkrankungen
ES2133807T3 (es)	1999-09-16	Compuestos de peptidilo y su uso terapeutico como inhibidores de metaloproteasas.
ATE377006T1 (de)	2007-11-15	Aus d-aminosäuren abgeleitete cystein- und serinproteasehemmer
ATE439853T1 (de)	2009-09-15	Zusammensetzung zur behandlung von ichthyosis unter verwendung von antitrypsin
NO20061736L (no)	1999-08-20	Krystallform av epotilon B
ATE193304T1 (de)	2000-06-15	Inhibitoren der menschlichen neutrophilenelastase
MEP90508A (en)	2011-12-20	New pharmaceutical composition
MX9800146A (es)	1998-03-31	Nuevos inhibidores de trombina, su preparacion y su uso.
ATE345136T1 (de)	2006-12-15	Cysteinprotease-hemmer mit 2-cyano-4-amino- pyrimidinstruktur und cathepsin-k-hemmender wirkung zur behandlung von entzündungen und anderen erkrankungen
SE9602263D0 (sv)	1996-06-07	New amino acid derivatives
DE60026279D1 (de)	2006-04-27	Zusammenstellungen zur prophylaxe und behandlung von allergien des typus i
DK0871454T3 (da)	2004-03-22	Phosphorholdige inhibitorer af cystein- og serinprotease
DE69814444D1 (de)	2003-06-12	Kombination von angiotensing-convertin-enzyme hemmern mit diuretikum zur behandlung von störungen der mikrozirkulation
ATE277943T1 (de)	2004-10-15	Trypsininhibitoren
IS5511A (is)	2000-05-26	Ný efnasambönd
DE69626671D1 (de)	2003-04-17	Fusionsproteine bestehend aus gewebefaktor-kunitzdomäne als inhibitoren des faktors viia
YU49422B (sh)	2006-01-16	Upotreba inhibitora ugljenične anhidraze za proizvodnju medikamenata za tretiranje makularnog edema ili makularne degeneracije izazvane starošću
ATE208793T1 (de)	2001-11-15	Thrombin-inhibitoren
DE69815143D1 (de)	2003-07-03	Behandlung von allergischen zuständen mit cystein- und serin-proteinase inhibitoren
ATE218877T1 (de)	2002-06-15	Bowman-birk-inhibitorzusammensetzungen zur behandlung von entzündungskrankheiten