ATE243215T1 - Neue 2-decarboxy-2-phosphinico prostaglandin f analoge - Google Patents

Neue 2-decarboxy-2-phosphinico prostaglandin f analoge

Info

Publication number
ATE243215T1
ATE243215T1 AT00950904T AT00950904T ATE243215T1 AT E243215 T1 ATE243215 T1 AT E243215T1 AT 00950904 T AT00950904 T AT 00950904T AT 00950904 T AT00950904 T AT 00950904T AT E243215 T1 ATE243215 T1 AT E243215T1
Authority
AT
Austria
Prior art keywords
compounds
decarboxy
analogue
new
glaucoma
Prior art date
Application number
AT00950904T
Other languages
English (en)
Inventor
Mitchell Anthony Delong
John August Wos
Biswanath De
Frank Hallock Ebetino
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of ATE243215T1 publication Critical patent/ATE243215T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/303—Cycloaliphatic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT00950904T 1999-08-04 2000-08-01 Neue 2-decarboxy-2-phosphinico prostaglandin f analoge ATE243215T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14713299P 1999-08-04 1999-08-04
PCT/US2000/020851 WO2001010873A1 (en) 1999-08-04 2000-08-01 Novel 2-decarboxy-2-phosphinico prostaglandin f analogs

Publications (1)

Publication Number Publication Date
ATE243215T1 true ATE243215T1 (de) 2003-07-15

Family

ID=22520396

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00950904T ATE243215T1 (de) 1999-08-04 2000-08-01 Neue 2-decarboxy-2-phosphinico prostaglandin f analoge

Country Status (12)

Country Link
US (1) US6372730B1 (de)
EP (1) EP1202999B1 (de)
JP (1) JP4846150B2 (de)
AT (1) ATE243215T1 (de)
AU (1) AU776375B2 (de)
CA (1) CA2380326C (de)
CO (1) CO5180630A1 (de)
DE (1) DE60003435T2 (de)
ES (1) ES2202156T3 (de)
IL (1) IL147771A0 (de)
NO (1) NO20020523L (de)
WO (1) WO2001010873A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2364948C (en) 1999-03-05 2011-04-26 Duke University C16 unsaturated fp-selective prostaglandins analogs
US6884858B2 (en) 1999-10-19 2005-04-26 Texas Petrochemicals Lp Process for preparing polyolefin products
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20060135609A1 (en) * 2004-10-21 2006-06-22 Duke University Ophthamological drugs
WO2007074604A1 (ja) 2005-12-26 2007-07-05 Ltt Bio-Pharma Co., Ltd. 水溶性非ペプチド性低分子薬物含有ナノ粒子
US20070254920A1 (en) * 2006-04-26 2007-11-01 Aerie Pharmaceuticals, Inc. Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use
KR101513318B1 (ko) * 2007-05-14 2015-04-17 가부시키가이샤 엘티티 바이오파마 서방성의 음하전기를 갖는 저분자 약물 함유 나노 입자
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
WO2010058669A1 (ja) * 2008-11-18 2010-05-27 株式会社Ｌｔｔバイオファーマ 新規プロスタグランジンｅ１誘導体及びそれを封入するナノ粒子
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
CN105319283A (zh) * 2014-07-17 2016-02-10 上海市农药研究所 检测三联吡啶含量的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171331A (en) 1978-06-05 1979-10-16 Miles Laboratories, Inc. 1 And 2-substituted analogues of certain prostaglandins
US5312832A (en) 1991-05-17 1994-05-17 Allergan, Inc. Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives
US5409911A (en) * 1992-09-11 1995-04-25 Merck & Co., Inc. Prostaglandin analog for treating osteoporosis
US5658897A (en) * 1996-04-08 1997-08-19 Allergan Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, 2-hydrocarbyl phosphinyloxyalkyl or phosphonamidoalkyl as therapeutic agents
HUP0004436A3 (en) * 1997-09-09 2001-09-28 Procter & Gamble Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
BR9811774A (pt) * 1997-09-09 2000-08-29 Procter & Gamble Tetraidroprostaglandinas aromáticas substituìdas por c16-c20 úteis como agonistas fp
SK3382000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders
US6121253A (en) * 1998-11-20 2000-09-19 Merck Frosst Canada & Co. Prostaglandin conjugates for treating or preventing bone disease

Also Published As

Publication number Publication date
EP1202999A1 (de) 2002-05-08
EP1202999B1 (de) 2003-06-18
US6372730B1 (en) 2002-04-16
DE60003435T2 (de) 2004-05-19
NO20020523L (no) 2002-04-02
AU6393300A (en) 2001-03-05
CA2380326A1 (en) 2001-02-15
ES2202156T3 (es) 2004-04-01
CO5180630A1 (es) 2002-07-30
AU776375B2 (en) 2004-09-09
WO2001010873A1 (en) 2001-02-15
CA2380326C (en) 2008-03-18
IL147771A0 (en) 2002-08-14
DE60003435D1 (de) 2003-07-24
JP2003506454A (ja) 2003-02-18
JP4846150B2 (ja) 2011-12-28
NO20020523D0 (no) 2002-02-01

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Legal Events

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