ATE243253T1 - Rezeptoren der wachstumsfaktoren aus fibroblasten - Google Patents

Rezeptoren der wachstumsfaktoren aus fibroblasten

Info

Publication number
ATE243253T1
ATE243253T1 AT91915163T AT91915163T ATE243253T1 AT E243253 T1 ATE243253 T1 AT E243253T1 AT 91915163 T AT91915163 T AT 91915163T AT 91915163 T AT91915163 T AT 91915163T AT E243253 T1 ATE243253 T1 AT E243253T1
Authority
AT
Austria
Prior art keywords
domain
fibroblasts
receptors
growth factors
repeats
Prior art date
Application number
AT91915163T
Other languages
English (en)
Inventor
Craig A Dionne
Gregg Crumley
Michael C Jaye
Joseph Schlessinger
Original Assignee
Rhone Poulenc Rorer Internat H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24193610&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE243253(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Internat H filed Critical Rhone Poulenc Rorer Internat H
Application granted granted Critical
Publication of ATE243253T1 publication Critical patent/ATE243253T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT91915163T 1990-07-06 1991-07-03 Rezeptoren der wachstumsfaktoren aus fibroblasten ATE243253T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54958790A 1990-07-06 1990-07-06
PCT/US1991/004745 WO1992000999A1 (en) 1990-07-06 1991-07-03 Fibroblast growth factor receptors

Publications (1)

Publication Number Publication Date
ATE243253T1 true ATE243253T1 (de) 2003-07-15

Family

ID=24193610

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91915163T ATE243253T1 (de) 1990-07-06 1991-07-03 Rezeptoren der wachstumsfaktoren aus fibroblasten

Country Status (10)

Country Link
US (1) US6344546B1 (de)
EP (2) EP0538404B1 (de)
JP (2) JP3615220B2 (de)
AT (1) ATE243253T1 (de)
AU (1) AU662107B2 (de)
CA (1) CA2086425C (de)
DE (1) DE69133281T2 (de)
DK (1) DK0538404T3 (de)
ES (1) ES2204886T3 (de)
WO (1) WO1992000999A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6228609B1 (en) * 1992-07-09 2001-05-08 Systemix, Inc. Soluble Flk-2 sequence
CA2231509C (en) * 1995-09-11 2008-07-08 Osteoarthritis Sciences, Inc. Protein tyrosine kinase inhibitors for treating osteoarthritis
US6214795B1 (en) 1996-11-12 2001-04-10 Praecis Pharmaceuticals, Inc. Peptide compounds useful for modulating FGF receptor activity
WO2000039311A1 (en) * 1998-12-31 2000-07-06 Advanced Research And Technology Institute Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2
US6657078B2 (en) * 2001-02-07 2003-12-02 Celanese International Corporation Low energy carbonylation process
NZ565511A (en) 2005-07-22 2011-03-31 Five Prime Therapeutics Inc Compositions and methods of treating disease with FGFR fusion proteins
PE20081250A1 (es) 2006-11-28 2008-10-07 Centelion FUSIONES Fc CON RECEPTOR PARA FGF SOLUBLE MODIFICADAS, CON ACTIVIDAD BIOLOGICA MEJORADA
SG193860A1 (en) 2008-06-04 2013-10-30 Amgen Inc Fgf21 mutants and uses thereof
CN102171343B (zh) 2008-08-04 2017-07-14 戊瑞治疗有限公司 Fgfr细胞外结构域酸性区突变蛋白
NZ592009A (en) 2008-10-10 2012-11-30 Amgen Inc Fgf21 mutants and uses thereof
BRPI1011404B1 (pt) 2009-05-05 2022-05-03 Amgen Inc Polipeptídeos mutantes fgf21, polipeptídeo de fusão, multímero, composição farmacêutica, ácido nucleico isolado, vetor e célula hospedeira
AU2010246038A1 (en) 2009-05-05 2011-12-01 Amgen Inc. FGF21 mutants and uses thereof
JP2012530493A (ja) * 2009-06-17 2012-12-06 アムジエン・インコーポレーテツド キメラポリペプチドおよびその使用
WO2011034940A1 (en) 2009-09-15 2011-03-24 Five Prime Therapeutics, Inc. Hair growth methods using fgfr4 extracellular domains
PT2498799T (pt) 2009-11-13 2016-11-04 Five Prime Therapeutics Inc Utilização de proteínas do domínio extracelular rfcf1 para tratar cancros caracterizados por mutações ativadoras dependentes de ligando em rfcf2
MX2012006397A (es) * 2009-12-02 2012-11-30 Amgen Inc PROTEINAS DE ENLACE QUE ENLAZAN A FGFR1C HUMANO, ß-KLOTHO HUMANA Y TANTO FGFR1C HUMANO COMO ß-KLOTHO HUMANA.
UA109888C2 (uk) 2009-12-07 2015-10-26 ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
WO2011084711A2 (en) 2009-12-17 2011-07-14 Five Prime Therapeutics, Inc. Hair growth methods using fgfr3 extracellular domains
CA2800311A1 (en) 2010-05-11 2011-11-17 Aveo Pharmaceuticals, Inc. Anti-fgfr2 antibodies
US8481038B2 (en) 2010-11-15 2013-07-09 Five Prime Therapeutics, Inc. Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
MX349293B (es) 2010-11-15 2017-07-21 Five Prime Therapeutics Inc * Tratamiento de cancer con dosis elevadas de proteinas de fusion del receptor del factor de crecimiento de fibroblastos 1 (fgfr1) solubles.
US8951972B2 (en) 2010-12-09 2015-02-10 Five Prime Therapeutics, Inc. FGFR1 extracellular domain combination therapies for lung cancer
WO2013074492A1 (en) 2011-11-14 2013-05-23 Five Prime Therapeutics, Inc. Methods of treating cancer
JP2016510751A (ja) 2013-03-06 2016-04-11 ジェネンテック， インコーポレイテッド 抗がん剤耐性を治療及び予防する方法
WO2015191986A1 (en) 2014-06-13 2015-12-17 Genentech, Inc. Methods of treating and preventing cancer drug resistance

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9001466D0 (en) * 1990-01-23 1990-03-21 Erba Carlo Spa Extracellular form of the human fibroblast growth factor receptor
WO1991000916A2 (en) * 1989-07-06 1991-01-24 The Regents Of The University Of California Receptors for fibroblast growth factors

Also Published As

Publication number Publication date
EP1403285A1 (de) 2004-03-31
JPH05508550A (ja) 1993-12-02
ES2204886T3 (es) 2004-05-01
DE69133281D1 (de) 2003-07-24
JP2004041176A (ja) 2004-02-12
DE69133281T2 (de) 2004-05-06
EP0538404A1 (de) 1993-04-28
AU8427391A (en) 1992-02-04
WO1992000999A1 (en) 1992-01-23
DK0538404T3 (da) 2003-10-13
AU662107B2 (en) 1995-08-24
CA2086425C (en) 2006-01-17
CA2086425A1 (en) 1992-01-07
EP0538404B1 (de) 2003-06-18
JP3996084B2 (ja) 2007-10-24
EP0538404A4 (en) 1993-05-26
JP3615220B2 (ja) 2005-02-02
US6344546B1 (en) 2002-02-05

Similar Documents

Publication Publication Date Title
DE69133281D1 (de) Rezeptoren der wachstumsfaktoren aus fibroblasten
NO931955L (no) Reseptorer for leukemiinhiberende faktor
ES2137931T3 (es) Proteinas gdf-1 y uog-1.
NO964650D0 (no) LAG-3 protein-opplöselige polypeptidfraksjoner, fremgangsmåte for fremstilling, teraupeutisk preparat og anti-idiotype antistoff
IT1242149B (it) Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
EP1009814A4 (de) Kdr, ein menschlicher tyrosin kinase rezeptor
DK0618976T3 (da) Syntetisk DNA-sekvens med forbedret insekticid virkning i majs
NO940736L (no) DNA sekvenser som koder for gelonin polypeptid
CY1107173T1 (el) Μεθοδοι και κυτταρα για την εκφραση ανασυνδυασμενων πρωτεϊνικων προϊοντων
DK0479948T3 (da) Sammensætninger og fremgangsmåder til syntese af natriuretisk protein-receptor B og anvendelsesfremgangsmåder
DE69529822D1 (de) Interleukin-15-rezeptoren
FI971896A7 (fi) BMP-tyyppi II-reseptoria koodaava cDNA
ATE277178T1 (de) C-typ lektine
NO922421L (no) Collagenbindende protein, samt fremstilling derav
WO2001055103A3 (en) Chimeric neuropeptide y receptors
ES8800353A1 (es) Procedimiento de clonacion de factor humano viii-r.
DE69333284D1 (de) Polypeptide mit serotoninerger (5ht5a) rezeptor-aktivität, für sie kodierende nukleinsäuren und ihre verwendung
DE60043664D1 (de) Dungen davon
WO1999021994A3 (en) Human vesicle membrane protein-like proteins
IL138585A (en) Vertebrate patched -2 protein
DE69130675D1 (de) Klonierung und expression eines rhoptry-assoziierten proteins aus p. falciparum

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0538404

Country of ref document: EP

EELA Cancelled due to lapse of time