ATE243528T1 - Antitumormittel enthaltend einen komplex einer oxidoreduktase und eines polymers und ein substrat des enzyms - Google Patents
Antitumormittel enthaltend einen komplex einer oxidoreduktase und eines polymers und ein substrat des enzymsInfo
- Publication number
- ATE243528T1 ATE243528T1 AT98115722T AT98115722T ATE243528T1 AT E243528 T1 ATE243528 T1 AT E243528T1 AT 98115722 T AT98115722 T AT 98115722T AT 98115722 T AT98115722 T AT 98115722T AT E243528 T1 ATE243528 T1 AT E243528T1
- Authority
- AT
- Austria
- Prior art keywords
- oxidoreductase
- antitumor agent
- substrate
- enzyme
- agent containing
- Prior art date
Links
- 102000004316 Oxidoreductases Human genes 0.000 title abstract 3
- 108090000854 Oxidoreductases Proteins 0.000 title abstract 3
- 239000002246 antineoplastic agent Substances 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title abstract 2
- 239000000758 substrate Substances 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
- C12Y117/03—Oxidoreductases acting on CH or CH2 groups (1.17) with oxygen as acceptor (1.17.3)
- C12Y117/03002—Xanthine oxidase (1.17.3.2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9240235A JPH1160499A (ja) | 1997-08-22 | 1997-08-22 | 抗腫瘍剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE243528T1 true ATE243528T1 (de) | 2003-07-15 |
Family
ID=17056469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98115722T ATE243528T1 (de) | 1997-08-22 | 1998-08-20 | Antitumormittel enthaltend einen komplex einer oxidoreduktase und eines polymers und ein substrat des enzyms |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0898968B1 (de) |
| JP (1) | JPH1160499A (de) |
| KR (1) | KR100572603B1 (de) |
| AT (1) | ATE243528T1 (de) |
| AU (1) | AU741472B2 (de) |
| CA (1) | CA2245397C (de) |
| DE (1) | DE69815769T2 (de) |
| ES (1) | ES2202704T3 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030157085A1 (en) | 1997-08-22 | 2003-08-21 | Hiroshi Maeda | Antitumor agents |
| ATE340592T1 (de) | 1999-04-23 | 2006-10-15 | Alza Corp | Konjugate enthaltend eine spaltbare bindung zur anwendung in einem liposom |
| US7238368B2 (en) * | 1999-04-23 | 2007-07-03 | Alza Corporation | Releasable linkage and compositions containing same |
| US7303760B2 (en) | 1999-04-23 | 2007-12-04 | Alza Corporation | Method for treating multi-drug resistant tumors |
| AU2001252650A1 (en) * | 2000-04-28 | 2001-11-12 | Effector Cell Institute | Novel derivative of cell chemotactic factor |
| JPWO2006080171A1 (ja) | 2005-01-31 | 2008-06-19 | 株式会社 エフェクター細胞研究所 | 免疫増強剤 |
| JPWO2006112362A1 (ja) * | 2005-04-18 | 2008-12-11 | 前田 浩 | 高分子型癌治療用医薬の製造方法 |
| EP1859810A1 (de) * | 2006-05-26 | 2007-11-28 | APIT Laboratories GmbH | Peg-modifizierte Arginin/lysin-Oxidoreduktase |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ225599A (en) * | 1987-08-04 | 1991-09-25 | Bristol Myers Co | Antibody-enzyme conjugates and combinations with prodrugs for the treatment of tumour cells |
| WO1991008770A1 (en) * | 1989-12-11 | 1991-06-27 | Immunomedics, Inc. | Method for antibody targeting of diagnostic or therapeutic agents |
| GB9421223D0 (en) * | 1994-10-21 | 1994-12-07 | Univ Alberta | Tissue imaging in gene therapy |
-
1997
- 1997-08-22 JP JP9240235A patent/JPH1160499A/ja not_active Withdrawn
-
1998
- 1998-08-18 AU AU80798/98A patent/AU741472B2/en not_active Ceased
- 1998-08-20 ES ES98115722T patent/ES2202704T3/es not_active Expired - Lifetime
- 1998-08-20 DE DE69815769T patent/DE69815769T2/de not_active Expired - Lifetime
- 1998-08-20 EP EP98115722A patent/EP0898968B1/de not_active Expired - Lifetime
- 1998-08-20 AT AT98115722T patent/ATE243528T1/de not_active IP Right Cessation
- 1998-08-21 CA CA002245397A patent/CA2245397C/en not_active Expired - Fee Related
- 1998-08-22 KR KR1019980034125A patent/KR100572603B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2245397C (en) | 2005-05-03 |
| AU741472B2 (en) | 2001-11-29 |
| ES2202704T3 (es) | 2004-04-01 |
| DE69815769D1 (de) | 2003-07-31 |
| JPH1160499A (ja) | 1999-03-02 |
| CA2245397A1 (en) | 1999-02-22 |
| EP0898968A1 (de) | 1999-03-03 |
| KR19990023798A (ko) | 1999-03-25 |
| DE69815769T2 (de) | 2004-05-19 |
| EP0898968B1 (de) | 2003-06-25 |
| KR100572603B1 (ko) | 2006-08-01 |
| AU8079898A (en) | 1999-03-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE324417T1 (de) | Polyphenolisches protein enthaltende bioadhäsive zusammensetzung | |
| IL143748A0 (en) | Substituted aryl or heteroarylamides having retinoid-like biological activity | |
| WO1998048852A3 (de) | Polymerbeschichtete stents | |
| ES2008718A6 (es) | Un metodo de preparacion de un sellador de silicona | |
| AU8865998A (en) | Improved multiparticulate tablet with quick disintegration | |
| ATE225665T1 (de) | Universell verwendbares bluttplasma | |
| DK1282669T3 (da) | Antibegroningssammensætning | |
| ATE243528T1 (de) | Antitumormittel enthaltend einen komplex einer oxidoreduktase und eines polymers und ein substrat des enzyms | |
| NO20000282D0 (no) | Dispersjon av titanpartikler omfattende et bindemiddel basert på polyorganosiloksan | |
| SG166661A1 (en) | Precursor compounds | |
| CA2319837A1 (en) | Hydroxylation activated drug release | |
| DE69814088D1 (de) | Galactoseoxidase enthaltende zusammensetzung und ihre verwendung | |
| EP1591526A3 (de) | Frazzled Nukleotidsequenzen, Expressions- produkte, Zusammensetzungen und Verwendungen | |
| CA2234377A1 (en) | Aqueous coating composition | |
| MY118864A (en) | Use of oxidation promoting chemicals in the oxidation of oxidizable galactose type of alcohol configuration containing polymer | |
| ATE493106T1 (de) | Oberflächenbehandlungsmittel für dentales hartgewebe | |
| DK1141069T3 (da) | Coatingsammensætning | |
| EP1148129A4 (de) | BETACELLULIN-VERäNDERUNG | |
| ES1044378U (es) | Indicador de paginas multiple y polivalente perfeccionado. | |
| DK0717929T3 (da) | Metode såvel som substans til hæmme af mikrobevækst på overflader såvel som substans til overfladebehandling |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |