ATE243695T1 - 5-bicycloindolverbindungen - Google Patents

5-bicycloindolverbindungen

Info

Publication number
ATE243695T1
ATE243695T1 AT99930958T AT99930958T ATE243695T1 AT E243695 T1 ATE243695 T1 AT E243695T1 AT 99930958 T AT99930958 T AT 99930958T AT 99930958 T AT99930958 T AT 99930958T AT E243695 T1 ATE243695 T1 AT E243695T1
Authority
AT
Austria
Prior art keywords
compounds
bicycloindole
disclosed
ht1d receptor
migrane
Prior art date
Application number
AT99930958T
Other languages
English (en)
Inventor
Abdelmalik Slassi
Jalaj Arora
Ashok Tehim
Original Assignee
Nps Allelix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Allelix Corp filed Critical Nps Allelix Corp
Application granted granted Critical
Publication of ATE243695T1 publication Critical patent/ATE243695T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT99930958T 1998-07-17 1999-07-15 5-bicycloindolverbindungen ATE243695T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/116,946 US6329390B1 (en) 1998-07-17 1998-07-17 5-Bicycloindole compounds
PCT/CA1999/000639 WO2000004019A1 (en) 1998-07-17 1999-07-15 5-bicycloindole compounds

Publications (1)

Publication Number Publication Date
ATE243695T1 true ATE243695T1 (de) 2003-07-15

Family

ID=22370203

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99930958T ATE243695T1 (de) 1998-07-17 1999-07-15 5-bicycloindolverbindungen

Country Status (8)

Country Link
US (1) US6329390B1 (de)
EP (1) EP1098896B1 (de)
JP (1) JP2002520412A (de)
AT (1) ATE243695T1 (de)
AU (1) AU767274B2 (de)
CA (1) CA2343748A1 (de)
DE (1) DE69909097D1 (de)
WO (1) WO2000004019A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2508290C (en) * 2002-12-20 2017-02-28 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof
CN102936240A (zh) * 2012-10-30 2013-02-20 浙江省医学科学院 一种(r)-5-取代-3-(n-苄氧羰基吡咯烷-2-基羰基)-1h-吲哚的合成方法
WO2025104490A1 (en) * 2023-11-14 2025-05-22 Mindset Pharma Inc. Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto
WO2025104491A1 (en) * 2023-11-14 2025-05-22 Mindset Pharma Inc. Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407447D0 (en) * 1994-04-14 1994-06-08 Glaxo Group Ltd Chemical compounds
CN1289479C (zh) * 1996-11-26 2006-12-13 Nps艾里利克斯有限公司 作为5－ht1d受体配位体的5－环吲哚化合物

Also Published As

Publication number Publication date
JP2002520412A (ja) 2002-07-09
EP1098896B1 (de) 2003-06-25
AU767274B2 (en) 2003-11-06
CA2343748A1 (en) 2000-01-27
DE69909097D1 (de) 2003-07-31
WO2000004019A1 (en) 2000-01-27
AU4765199A (en) 2000-02-07
US6329390B1 (en) 2001-12-11
EP1098896A1 (de) 2001-05-16

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties