ATE243707T1 - Organische festphasensynthese - Google Patents
Organische festphasensyntheseInfo
- Publication number
- ATE243707T1 ATE243707T1 AT96943085T AT96943085T ATE243707T1 AT E243707 T1 ATE243707 T1 AT E243707T1 AT 96943085 T AT96943085 T AT 96943085T AT 96943085 T AT96943085 T AT 96943085T AT E243707 T1 ATE243707 T1 AT E243707T1
- Authority
- AT
- Austria
- Prior art keywords
- solid phase
- phase synthesis
- organic solid
- glyco
- enzymatically
- Prior art date
Links
- 238000010532 solid phase synthesis reaction Methods 0.000 title 1
- 150000001720 carbohydrates Chemical group 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 238000007171 acid catalysis Methods 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000012038 nucleophile Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Catalysts (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Carbon And Carbon Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9525007.2A GB9525007D0 (en) | 1995-12-07 | 1995-12-07 | Solid phase organic synthesis |
| GBGB9613921.7A GB9613921D0 (en) | 1996-07-03 | 1996-07-03 | Solid phase organic synthesis |
| PCT/EP1996/005535 WO1997020855A2 (en) | 1995-12-07 | 1996-12-06 | Solid phase organic synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE243707T1 true ATE243707T1 (de) | 2003-07-15 |
Family
ID=26308244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96943085T ATE243707T1 (de) | 1995-12-07 | 1996-12-06 | Organische festphasensynthese |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6492136B1 (de) |
| EP (1) | EP0871650B1 (de) |
| JP (1) | JP2000502068A (de) |
| AT (1) | ATE243707T1 (de) |
| AU (1) | AU719356B2 (de) |
| CA (1) | CA2239298A1 (de) |
| DE (1) | DE69628851D1 (de) |
| WO (1) | WO1997020855A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19626762A1 (de) | 1996-07-03 | 1998-01-08 | Basf Ag | Enzymatisch spaltbare Linker für Festphasensynthesen |
| US6756489B1 (en) * | 1997-08-08 | 2004-06-29 | Aventis Pharma Deutschland Gmbh | Substituted tetrahydropyrane derivatives, method for producing same, their use as medicine or diagnostic agent, as well as medicine containing same |
| ATE478083T1 (de) | 1999-03-05 | 2010-09-15 | Massachusetts Inst Technology | Linker zur synthese von oligosacchariden auf festträgern |
| DE19924606A1 (de) * | 1999-05-28 | 2000-11-30 | Graffinity Pharm Design Gmbh | Ligand-Anker-Konjugate |
| CN103739535B (zh) * | 2013-11-29 | 2016-06-08 | 温州大学 | 一种s-取代芳磺酸酯的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659774A (en) * | 1985-11-01 | 1987-04-21 | American Hoechst Corporation | Support for solid-phase oligonucleotide synthesis |
| US5679769A (en) * | 1994-03-15 | 1997-10-21 | Sloan-Kettering Institute For Cancer Research | Synthesis of asparagine-linked glycopeptides on a polymeric solid support |
-
1996
- 1996-12-06 WO PCT/EP1996/005535 patent/WO1997020855A2/en not_active Ceased
- 1996-12-06 DE DE69628851T patent/DE69628851D1/de not_active Expired - Lifetime
- 1996-12-06 JP JP9520999A patent/JP2000502068A/ja not_active Ceased
- 1996-12-06 US US09/077,496 patent/US6492136B1/en not_active Expired - Fee Related
- 1996-12-06 AU AU12033/97A patent/AU719356B2/en not_active Ceased
- 1996-12-06 CA CA002239298A patent/CA2239298A1/en not_active Abandoned
- 1996-12-06 AT AT96943085T patent/ATE243707T1/de not_active IP Right Cessation
- 1996-12-06 EP EP96943085A patent/EP0871650B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2239298A1 (en) | 1997-06-12 |
| EP0871650A2 (de) | 1998-10-21 |
| EP0871650B1 (de) | 2003-06-25 |
| WO1997020855A3 (en) | 1997-07-10 |
| WO1997020855A2 (en) | 1997-06-12 |
| AU1203397A (en) | 1997-06-27 |
| AU719356B2 (en) | 2000-05-04 |
| JP2000502068A (ja) | 2000-02-22 |
| US6492136B1 (en) | 2002-12-10 |
| DE69628851D1 (de) | 2003-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Cohen et al. | Application of serine-and threonine-derived cyclic sulfamidates for the preparation of S-linked glycosyl amino acids in solution-and solid-phase peptide synthesis | |
| DE3587883T2 (de) | Synthetische Prosthetogene und ihre Verwendung in Enzymkopplungstests. | |
| Schwartz et al. | A kinetic characterization of the glycosyltransferase activity of Eschericia coli PBP1b and development of a continuous fluorescence assay | |
| Nägele et al. | Chemoenzymatic synthesis of N-Ras lipopeptides | |
| DK0751144T3 (da) | Nye antracyclin-pro-drugs, fremgangsmåde til fremstilling deraf samt antitumorsammensætninger og et komponentkit indeholdende disse pro-drugs | |
| Wang et al. | Synthesis of a novel esterase-sensitive cyclic prodrug system for peptides that utilizes a “trimethyl lock”-facilitated lactonization reaction | |
| TR199902326T2 (xx) | Anti-hiperkolesterinemikler olarak ikameli piridinler ve bifeniller. | |
| FI944568A0 (fi) | Oligonukleotidien synteesi | |
| DK1053355T3 (da) | PNA- og DNA-konjugater og metoder til fremstilling heraf | |
| FR2379531A1 (fr) | Nouvelle substance physiologiquement active inhibant l'activite enzymatique de l'esterase et son mode de production | |
| Jeong et al. | Cyclic Guanidino-Sugars with Low p K a as Transition-State Analog Inhibitors of Glycosidases: Neutral Instead of Charged Species Are the Active Forms | |
| EA199800288A1 (ru) | Производные 5-o-дезозаминил-6-o-метилэритронолида а, способ их получения и их применение для получения биологически активных продуктов | |
| PT1095053E (pt) | Ligantes arilsulfona para analise por espectrometria de massa | |
| CA2064793C (en) | Hydrolytic enzyme inhibitors and substrates and assays, methods and kits embodying same | |
| BR9710190A (pt) | Ligante divisível enzimaticamente processo para sua preparação e uso do mesmo | |
| Garrard et al. | Inhibition of trypanothione reductase by substrate analogues | |
| Trombotto et al. | Straightforward route for anchoring a glucosyl moiety onto nucleophilic species: reaction of amines and alcohols with carboxymethyl 3, 4, 6-Tri-O-acetyl-α-D-glucopyranoside 2-O-Lactone | |
| ATE243707T1 (de) | Organische festphasensynthese | |
| Cameron et al. | Biomimetic monoacylation of diols in water. Lanthanide-promoted reactions of methyl benzoyl phosphate | |
| US5308766A (en) | Hydrolytic enzyme inhibitors/inactivators and methods for using same | |
| Bensel et al. | Pivalase catalytic antibodies: towards abzymatic activation of prodrugs | |
| Dubey et al. | Modification of the Thiourea Linkage of a Fluorescein− Oligonucleotide Conjugate to a Guanidinium Motif during Ammonia Deprotection | |
| Völkert et al. | Phenylhydrazide as an enzyme-labile protecting group in peptide synthesis | |
| Pal et al. | Detecting precatalytic conformational changes in F1-ATPase with 4-benzoyl (benzoyl)-1-amidofluorescein, a novel fluorescent nucleotide site-specific photoaffinity label. | |
| Mugford et al. | Unexpected subtilisin-catalyzed hydrolysis of a sulfinamide bond in preference to a carboxamide bond in N-acyl sulfinamides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |