ATE244236T1 - Substituierte azole - Google Patents

Substituierte azole

Info

Publication number: ATE244236T1
Authority: AT; Austria
Prior art keywords: substituted azoles; azoles; substituted
Prior art date: 1999-04-14

Application number

AT00922630T

Other languages

English (en)

Inventor

Laszlo Revesz

Achim Schlapbach

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-14

Filing date

2000-04-12

Publication date

2003-07-15

1999-04-14 Priority claimed from GBGB9908532.6A external-priority patent/GB9908532D0/en

1999-04-14 Priority claimed from GBGB9908531.8A external-priority patent/GB9908531D0/en

2000-04-12 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2003-07-15 Application granted granted Critical

2003-07-15 Publication of ATE244236T1 publication Critical patent/ATE244236T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Hematology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT00922630T 1999-04-14 2000-04-12 Substituierte azole ATE244236T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9908532.6A GB9908532D0 (en)	1999-04-14	1999-04-14	Organic compounds
GBGB9908531.8A GB9908531D0 (en)	1999-04-14	1999-04-14	Organic compounds
PCT/EP2000/003290 WO2000063204A2 (de)	1999-04-14	2000-04-12	Substituted azoles

Publications (1)

Publication Number	Publication Date
ATE244236T1 true ATE244236T1 (de)	2003-07-15

Family

ID=26315413

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00922630T ATE244236T1 (de)	1999-04-14	2000-04-12	Substituierte azole

Country Status (25)

Country	Link
US (1)	US6579874B2 (de)
EP (1)	EP1224180B1 (de)
JP (1)	JP2003503311A (de)
KR (1)	KR20010108504A (de)
CN (1)	CN1378544A (de)
AR (1)	AR023465A1 (de)
AT (1)	ATE244236T1 (de)
AU (1)	AU4295300A (de)
BR (1)	BR0010598A (de)
CA (1)	CA2370417A1 (de)
CO (1)	CO5170501A1 (de)
CZ (1)	CZ20013696A3 (de)
DE (1)	DE60003709T2 (de)
DK (1)	DK1224180T3 (de)
ES (1)	ES2202114T3 (de)
HU (1)	HUP0302747A2 (de)
IL (1)	IL145836A0 (de)
MX (1)	MXPA01010434A (de)
NO (1)	NO20014987L (de)
PE (1)	PE20010031A1 (de)
PL (1)	PL364789A1 (de)
PT (1)	PT1224180E (de)
SK (1)	SK14562001A3 (de)
TR (1)	TR200102967T2 (de)
WO (1)	WO2000063204A2 (de)

Families Citing this family (56)

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ATE396978T1 (de)	1999-10-07	2008-06-15	Amgen Inc	Triazin-kinase-hemmer
ES2254238T3 (es)	1999-10-27	2006-06-16	Novartis Ag	Compuestos de tiazol e imidazo(4,5-b)piridina y su uso farmaceutico.
MXPA02007957A (es) *	2000-02-17	2002-11-29	Amgen Inc	Inhibidores de cinasas.
ATE430742T1 (de)	2000-12-21	2009-05-15	Smithkline Beecham Corp	Pyrimidinamine als angiogenesemodulatoren
EP1354603A1 (de) *	2000-12-26	2003-10-22	Takeda Chemical Industries, Ltd.	Begleitmedikamente
WO2002062792A1 (en) *	2001-02-02	2002-08-15	Takeda Chemical Industries, Ltd.	Jnk inhibitor
ES2251582T3 (es)	2001-03-09	2006-05-01	Pfizer Products Inc.	Compuestos antiinflamatorios de bencimidazol.
DE60210755T2 (de)	2001-03-09	2006-11-16	Pfizer Products Inc., Groton	Triazolopyridine als entzündungshemmende mittel
ATE304009T1 (de)	2001-04-04	2005-09-15	Pfizer Prod Inc	Neue benzotriazole mit entzündungshemmender wirkung
US20050080113A1 (en) *	2001-06-11	2005-04-14	Shigenori Ohkawa	Medicinal compositions
TWI231757B (en) *	2001-09-21	2005-05-01	Solvay Pharm Bv	1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
US7109216B2 (en)	2001-09-21	2006-09-19	Solvay Pharmaceuticals B.V.	1H-imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
AU2002333852B2 (en)	2001-09-21	2006-07-13	Solvay Pharmaceuticals B.V.	Novel 4,5-dihydro-1H-pyrazole derivativeshaving CB1-antagonistic activity
US7473695B2 (en) *	2001-10-22	2009-01-06	Mitsubishi Tanabe Pharma Corporation	4-imidazolin-2-one compounds
EP1458385A4 (de) *	2001-12-19	2005-12-21	Merck & Co Inc	Heteroaryl-substituierte imidazol-modulatoren des metabotropen glutamat-rezeptors-5
AR039241A1 (es) *	2002-04-04	2005-02-16	Biogen Inc	Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos
ES2278170T3 (es)	2002-07-09	2007-08-01	BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG	Composiciones farmaceuticas de anticolinergicos e inhibidores de la quinasa p38 en el tratamiento de enfermedades respiratorias.
AU2003268064A1 (en) *	2002-08-09	2004-02-25	Astrazeneca Ab	Oxadiazoles as modulators of metabotropic glutamate receptor-5
KR20050033070A (ko)	2002-08-09	2005-04-08	아스트라제네카 에이비이	메타보트로픽 글루타메이트 수용체-5의 조절제로서[1,2,4]옥사디아졸
AU2003264018A1 (en) *	2002-08-09	2004-02-25	Astrazeneca Ab	Compounds having an activity at metabotropic glutamate receptors
US7037923B2 (en)	2002-08-30	2006-05-02	Pfizer, Inc.	Alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines
US6949652B2 (en)	2002-08-30	2005-09-27	Pfizer, Inc.	Crystalline forms of 3-isopropyl-6-[4-(2,5-difluoro-phenyl)-oxazol-5-yl]-[1,2,4]triazolo-[4,3-A]pyridine
PA8579601A1 (es)	2002-08-30	2004-05-07	Pfizer Prod Inc	Compuestos antiinflamatorios de di y trifloruro-triazolo-piridinas
MXPA05002123A (es) *	2002-08-30	2005-06-06	Pfizer Prod Inc	Nuevos procedimientos e intermedios para preparar triazolo-piridinas.
US7012143B2 (en)	2002-08-30	2006-03-14	Dombroski Mark A	Cycloalkyl-[4-(difluorophenyl)-oxazol-5-yl]-triazolo-pyridines
US7005523B2 (en)	2002-08-30	2006-02-28	Pfizer Inc.	Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines
UA80295C2 (en) *	2002-09-06	2007-09-10	Biogen Inc	Pyrazolopyridines and using the same
ATE457716T1 (de)	2002-12-30	2010-03-15	Angiotech Int Ag	Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
DE602004028800D1 (en)	2003-02-07	2010-10-07	Daiichi Sankyo Co Ltd	Pyrazolderivat
ES2264795T3 (es)	2003-02-14	2007-01-16	Pfizer Products Inc.	Triazolo-piridinas como compuestos antiinflamatorios.
MY143245A (en) *	2004-04-28	2011-04-15	Mitsubishi Tanabe Pharma Corp	4- 2-(cycloalkylamino)pyrimidin-4-yl-(phenyl)-imidazolin-2-one derivatives as p38 map-kinase inhibitors for the treatment of inflammatory diseases
CA2570318A1 (en) *	2004-06-30	2006-01-12	Banyu Pharmaceutical Co., Ltd.	Biaryl derivatives
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
US9777053B2 (en) *	2006-02-08	2017-10-03	The General Hospital Corporation	Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
ES2301380B1 (es)	2006-08-09	2009-06-08	Laboratorios Almirall S.A.	Nuevos derivados de 1,7-naftiridina.
ES2320955B1 (es)	2007-03-02	2010-03-16	Laboratorios Almirall S.A.	Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
ES2329639B1 (es)	2007-04-26	2010-09-23	Laboratorios Almirall S.A.	Nuevos derivados de 4,8-difenilpoliazanaftaleno.
CA2685529A1 (en)	2007-04-30	2008-11-06	Abbott Laboratories	Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme
EP1992344A1 (de)	2007-05-18	2008-11-19	Institut Curie	P38 Alpha als therapeutisches Target für Erkrankungen, die mit einer FGFR3- Mutation assoziiert sind
WO2009094224A1 (en)	2008-01-25	2009-07-30	Millennium Pharmaceuticals, Inc.	Thiophenes and their use as phosphatidylinositol 3-kinase (pi3k) inhibitors
EP2108641A1 (de)	2008-04-11	2009-10-14	Laboratorios Almirall, S.A.	Neue substituierte Spiro[Cycloalkyl-1,3'-indo]-2'(1'H)-on-Derivate und ihre Verwendung als p38 mitogen-activated Kinase Inhibitoren
EP2113503A1 (de)	2008-04-28	2009-11-04	Laboratorios Almirall, S.A.	Neue substituierte Indolin-2-on- Derivate und ihre Verwendung als p39 mitogen-activated Kinase Inhibitoren
US8796314B2 (en)	2009-01-30	2014-08-05	Millennium Pharmaceuticals, Inc.	Heteroaryls and uses thereof
CA2750935A1 (en)	2009-01-30	2010-08-12	Millennium Pharmaceuticals, Inc.	Heteroaryls and their use as pi3k inhibitors
US9090601B2 (en)	2009-01-30	2015-07-28	Millennium Pharmaceuticals, Inc.	Thiazole derivatives
NZ596123A (en) *	2009-05-19	2014-08-29	Dow Agrosciences Llc	Compounds and methods for controlling fungi
EP2322176A1 (de)	2009-11-11	2011-05-18	Almirall, S.A.	Neue 7-Phenyl-[1,2,4]triazol[4,3-a]pyridin-3(2H)on-Derivate
JP2013533318A (ja)	2010-08-11	2013-08-22	ミレニアムファーマシューティカルズ，インコーポレイテッド	ヘテロアリールおよびその使用
PH12013500274A1 (en)	2010-08-11	2013-03-04	Millennium Pharm Inc	Heteroaryls and uses thereof
WO2012021611A1 (en)	2010-08-11	2012-02-16	Millennium Pharmaceuticals, Inc.	Heteroaryls and uses thereof
CA2814688A1 (en)	2010-10-13	2012-04-19	Millennium Pharmaceuticals, Inc.	Heteroaryls and uses thereof
AR086113A1 (es)	2011-04-30	2013-11-20	Abbott Lab	Isoxazolinas como agentes terapeuticos
US20190060286A1 (en)	2016-02-29	2019-02-28	University Of Florida Research Foundation, Incorpo	Chemotherapeutic Methods
JPWO2018159650A1 (ja) *	2017-02-28	2019-12-19	東レ株式会社	グアニジン誘導体及びその医薬用途
US12441707B2 (en)	2019-12-30	2025-10-14	Tyra Biosciences, Inc.	Indazole compounds

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US5658903A (en) *	1995-06-07	1997-08-19	Smithkline Beecham Corporation	Imidazole compounds, compositions and use
US5739143A (en) *	1995-06-07	1998-04-14	Smithkline Beecham Corporation	Imidazole compounds and compositions
DE69627006T2 (de) *	1995-08-10	2004-01-15	Merck & Co Inc	2-substituierte aryl-pyrrolen, zusammensetzungen solche verbindungen enthaltend und deren verwendung
US6492516B1 (en) *	1999-05-14	2002-12-10	Merck & Co., Inc.	Compounds having cytokine inhibitory activity

2000
- 2000-04-11 CO CO00026470A patent/CO5170501A1/es not_active Application Discontinuation
- 2000-04-12 ES ES00922630T patent/ES2202114T3/es not_active Expired - Lifetime
- 2000-04-12 BR BR0010598-8A patent/BR0010598A/pt not_active IP Right Cessation
- 2000-04-12 DK DK00922630T patent/DK1224180T3/da active
- 2000-04-12 AU AU42953/00A patent/AU4295300A/en not_active Abandoned
- 2000-04-12 KR KR1020017013086A patent/KR20010108504A/ko not_active Withdrawn
- 2000-04-12 EP EP00922630A patent/EP1224180B1/de not_active Expired - Lifetime
- 2000-04-12 WO PCT/EP2000/003290 patent/WO2000063204A2/de not_active Ceased
- 2000-04-12 DE DE60003709T patent/DE60003709T2/de not_active Expired - Fee Related
- 2000-04-12 AR ARP000101686A patent/AR023465A1/es unknown
- 2000-04-12 CA CA002370417A patent/CA2370417A1/en not_active Abandoned
- 2000-04-12 PT PT00922630T patent/PT1224180E/pt unknown
- 2000-04-12 CN CN00807552A patent/CN1378544A/zh active Pending
- 2000-04-12 PE PE2000000337A patent/PE20010031A1/es not_active Application Discontinuation
- 2000-04-12 SK SK1456-2001A patent/SK14562001A3/sk unknown
- 2000-04-12 JP JP2000612294A patent/JP2003503311A/ja active Pending
- 2000-04-12 TR TR2001/02967T patent/TR200102967T2/xx unknown
- 2000-04-12 PL PL00364789A patent/PL364789A1/xx not_active Application Discontinuation
- 2000-04-12 MX MXPA01010434A patent/MXPA01010434A/es unknown
- 2000-04-12 HU HU0302747A patent/HUP0302747A2/hu unknown
- 2000-04-12 AT AT00922630T patent/ATE244236T1/de not_active IP Right Cessation
- 2000-04-12 CZ CZ20013696A patent/CZ20013696A3/cs unknown
- 2000-04-12 IL IL14583600A patent/IL145836A0/xx unknown
2001
- 2001-10-12 US US09/975,913 patent/US6579874B2/en not_active Expired - Fee Related
- 2001-10-12 NO NO20014987A patent/NO20014987L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AR023465A1 (es)	2002-09-04
KR20010108504A (ko)	2001-12-07
CO5170501A1 (es)	2002-06-27
WO2000063204A2 (de)	2000-10-26
JP2003503311A (ja)	2003-01-28
BR0010598A (pt)	2002-02-05
CZ20013696A3 (cs)	2002-02-13
NO20014987L (no)	2001-12-14
TR200102967T2 (tr)	2002-01-21
DK1224180T3 (da)	2003-10-20
DE60003709T2 (de)	2004-12-23
EP1224180B1 (de)	2003-07-02
MXPA01010434A (es)	2002-03-27
AU4295300A (en)	2000-11-02
SK14562001A3 (sk)	2002-03-05
CA2370417A1 (en)	2000-10-26
PL364789A1 (en)	2004-12-13
WO2000063204A3 (de)	2002-05-23
ES2202114T3 (es)	2004-04-01
EP1224180A2 (de)	2002-07-24
CN1378544A (zh)	2002-11-06
US6579874B2 (en)	2003-06-17
NO20014987D0 (no)	2001-10-12
IL145836A0 (en)	2002-07-25
PE20010031A1 (es)	2001-02-23
DE60003709D1 (de)	2003-08-07
PT1224180E (pt)	2003-11-28
US20020049220A1 (en)	2002-04-25
HUP0302747A2 (hu)	2003-12-29

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