ATE244571T1 - Inhibitorische immunglobulin-polypeptide gegen den pdgf beta-rezeptor - Google Patents

Inhibitorische immunglobulin-polypeptide gegen den pdgf beta-rezeptor

Info

Publication number
ATE244571T1
ATE244571T1 AT93900793T AT93900793T ATE244571T1 AT E244571 T1 ATE244571 T1 AT E244571T1 AT 93900793 T AT93900793 T AT 93900793T AT 93900793 T AT93900793 T AT 93900793T AT E244571 T1 ATE244571 T1 AT E244571T1
Authority
AT
Austria
Prior art keywords
beta receptor
immunolobulin
inhibitory
polypeptides against
pdgf beta
Prior art date
Application number
AT93900793T
Other languages
English (en)
Inventor
Vanitha Ramakrishnan
Maria A Escobedo
Larry J Fretto
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Application granted granted Critical
Publication of ATE244571T1 publication Critical patent/ATE244571T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93900793T 1991-12-02 1992-12-01 Inhibitorische immunglobulin-polypeptide gegen den pdgf beta-rezeptor ATE244571T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80179591A 1991-12-02 1991-12-02
PCT/US1992/010359 WO1993010805A1 (en) 1991-12-02 1992-12-01 Inhibitory immunoglobulin polypeptides to human pdgf beta receptor

Publications (1)

Publication Number Publication Date
ATE244571T1 true ATE244571T1 (de) 2003-07-15

Family

ID=25182043

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93900793T ATE244571T1 (de) 1991-12-02 1992-12-01 Inhibitorische immunglobulin-polypeptide gegen den pdgf beta-rezeptor

Country Status (10)

Country Link
EP (2) EP0619738B1 (de)
JP (3) JP3455743B2 (de)
AT (1) ATE244571T1 (de)
CA (1) CA2124958C (de)
DE (1) DE69233125T2 (de)
NZ (1) NZ246242A (de)
PL (1) PL171920B1 (de)
RU (1) RU2194760C2 (de)
SG (1) SG72635A1 (de)
WO (1) WO1993010805A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6228600B1 (en) 1992-07-20 2001-05-08 The United States Of America As Represented By The Department Of Health And Human Services Immunoassays for the alpha platelet-derived growth factor receptor
US7252929B2 (en) 1989-02-09 2007-08-07 United States Of America, As Represented By The Secretary, Dept Of Health & Human Services Methods for identifying alpha PDGFR agonists and antagonists
DE69231128T2 (de) * 1991-01-31 2001-02-15 Cor Therapeutics, Inc. Domänen von extrazellulären bereichen von menschlichen blutplättchen abstammenden wachstumsfaktor rezeptor-polypeptiden
US5817310A (en) * 1991-12-02 1998-10-06 Cor Therapeutics, Inc. Inhibitory immunoglobulin polypeptides to human PDGF beta receptor
WO1994019016A1 (en) * 1993-02-25 1994-09-01 Zymogenetics, Inc. Inhibition of intimal hyperplasia using antibodies to pdgf receptors
US5976534A (en) * 1993-02-25 1999-11-02 Zymogenetics, Inc. Inhibition of intimal hyperplasia using antibodies to PDGF receptors and heparin
US5620687A (en) * 1993-02-25 1997-04-15 Zymogenetics, Inc. Inhibition of intimal hyperplasia using antibodies to PDGF beta receptors
US6908910B2 (en) 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US5504074A (en) 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
US7087592B1 (en) 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
JP2006526025A (ja) 2003-05-28 2006-11-16 エントレメッド インコーポレイテッド 抗血管新生剤
DE10337368A1 (de) * 2003-08-08 2005-03-03 Technische Universität Dresden Verfahren und Mittel zur Diagnose und Behandlung von Pankreastumoren
CA2558014A1 (en) 2004-03-12 2005-09-29 Entremed, Inc. Antiangiogenic agents
JP2009530388A (ja) 2006-03-20 2009-08-27 エントレメッド インコーポレイテッド ２−メトキシエストラジオールの疾患修飾性抗関節炎活性
CN103694351A (zh) * 2007-06-05 2014-04-02 耶鲁大学 受体酪氨酸激酶抑制剂及其使用方法
DK2321351T3 (en) * 2008-08-18 2017-12-18 Pfizer ANTIBODIES AGAINST CCR2
AR085091A1 (es) 2011-01-26 2013-09-11 Kolltan Pharmaceuticals Inc Anticuerpos anti-kit y sus usos
JP6483442B2 (ja) * 2011-12-05 2019-03-13 エックス−ボディ インコーポレイテッド Ｐｄｇｆ受容体ベータ結合ポリペプチド
EP3381943B1 (de) 2012-07-25 2022-03-16 Celldex Therapeutics, Inc. Anti-kit-antikörper und verwendungen davon
JO3405B1 (ar) 2013-01-09 2019-10-20 Regeneron Pharma الأجسام المضادة لمضاد مستقبل عامل النمو المشتق من الصفائح الدموية - بيتا واستخداماتها
CN113975386A (zh) 2014-05-23 2022-01-28 塞尔德克斯医疗公司 嗜酸性粒细胞或肥大细胞相关病症的治疗

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339356C (en) * 1988-02-02 1997-08-26 Lewis T. Williams Human platelet-derived growth factor receptor
ES2133269T3 (es) * 1989-02-09 1999-09-16 Us Health Gen receptor del factor de crecimiento derivado de plaquetas de tipo oc.

Also Published As

Publication number Publication date
SG72635A1 (en) 2000-05-23
NZ246242A (en) 1996-01-26
AU3232893A (en) 1993-06-28
JP3732385B2 (ja) 2006-01-05
JP2000355600A (ja) 2000-12-26
RU94031472A (ru) 1996-04-20
EP1350799A3 (de) 2003-12-03
CA2124958A1 (en) 1993-06-10
EP0619738A4 (en) 1996-07-03
EP0619738B1 (de) 2003-07-09
RU2194760C2 (ru) 2002-12-20
AU672377B2 (en) 1996-10-03
DE69233125D1 (de) 2003-08-14
DE69233125T2 (de) 2004-04-22
EP0619738A1 (de) 1994-10-19
CA2124958C (en) 2007-02-13
WO1993010805A1 (en) 1993-06-10
JP3455743B2 (ja) 2003-10-14
EP1350799A2 (de) 2003-10-08
JP2000355548A (ja) 2000-12-26
PL171920B1 (pl) 1997-06-30
JPH07501806A (ja) 1995-02-23

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