ATE245447T1 - Inhibitor von gehirnödemen - Google Patents
Inhibitor von gehirnödemenInfo
- Publication number
- ATE245447T1 ATE245447T1 AT96919984T AT96919984T ATE245447T1 AT E245447 T1 ATE245447 T1 AT E245447T1 AT 96919984 T AT96919984 T AT 96919984T AT 96919984 T AT96919984 T AT 96919984T AT E245447 T1 ATE245447 T1 AT E245447T1
- Authority
- AT
- Austria
- Prior art keywords
- endothelin antagonist
- treating
- brain edemas
- edemas
- preventing
- Prior art date
Links
- 206010048962 Brain oedema Diseases 0.000 title abstract 6
- 208000006752 brain edema Diseases 0.000 title abstract 6
- 239000003112 inhibitor Substances 0.000 title 1
- 239000002308 endothelin receptor antagonist Substances 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960003065 bosentan Drugs 0.000 abstract 1
- SXTRWVVIEPWAKM-UHFFFAOYSA-N bosentan hydrate Chemical compound O.COC1=CC=CC=C1OC(C(=NC(=N1)C=2N=CC=CN=2)OCCO)=C1NS(=O)(=O)C1=CC=C(C(C)(C)C)C=C1 SXTRWVVIEPWAKM-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16006095 | 1995-06-02 | ||
| PCT/JP1996/001438 WO1996038173A1 (en) | 1995-06-02 | 1996-05-29 | Brain edema inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE245447T1 true ATE245447T1 (de) | 2003-08-15 |
Family
ID=15707042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96919984T ATE245447T1 (de) | 1995-06-02 | 1996-05-29 | Inhibitor von gehirnödemen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5945448A (de) |
| EP (1) | EP0838223B1 (de) |
| JP (1) | JP4011114B2 (de) |
| KR (1) | KR100399797B1 (de) |
| CN (1) | CN1083261C (de) |
| AT (1) | ATE245447T1 (de) |
| AU (1) | AU700182B2 (de) |
| BR (1) | BR9608413A (de) |
| CA (1) | CA2218028C (de) |
| DE (1) | DE69629195T2 (de) |
| DK (1) | DK0838223T3 (de) |
| ES (1) | ES2202449T3 (de) |
| PT (1) | PT838223E (de) |
| TR (1) | TR199701497T1 (de) |
| TW (1) | TW460286B (de) |
| WO (1) | WO1996038173A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482857B1 (en) | 1998-07-17 | 2002-11-19 | The University Of Texas Southwestern Medical Center | Compositions which contain triterpenes for regulating hair growth |
| US6124362A (en) * | 1998-07-17 | 2000-09-26 | The Procter & Gamble Company | Method for regulating hair growth |
| TWI232102B (en) * | 2001-07-17 | 2005-05-11 | Shionogi & Co | A pharmaceutical formulation for injection |
| JP2007217438A (ja) * | 2001-07-17 | 2007-08-30 | Shionogi & Co Ltd | 注射用医薬製剤 |
| JP2006506445A (ja) | 2002-08-28 | 2006-02-23 | ホリス − イーデン ファーマスーティカルズ、 インコーポレイテッド | 治療処置の方法 |
| US7861479B2 (en) | 2005-01-14 | 2011-01-04 | Airlite Plastics, Co. | Insulated foam panel forms |
| AU2007225139A1 (en) * | 2006-03-13 | 2007-09-20 | Encysive Pharmaceuticals, Inc. | Methods and compositions for treatment of diastolic heart failure |
| US8080549B2 (en) | 2007-01-12 | 2011-12-20 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
| US8071596B2 (en) | 2007-01-12 | 2011-12-06 | Concert Pharmaceuticals, Inc. | Endothelin receptor antagonists |
| US8919067B2 (en) | 2011-10-31 | 2014-12-30 | Airlite Plastics Co. | Apparatus and method for construction of structures utilizing insulated concrete forms |
| US8887465B2 (en) | 2012-01-13 | 2014-11-18 | Airlite Plastics Co. | Apparatus and method for construction of structures utilizing insulated concrete forms |
| USD713975S1 (en) | 2012-07-30 | 2014-09-23 | Airlite Plastics Co. | Insulative insert for insulated concrete form |
| US10787827B2 (en) | 2016-11-14 | 2020-09-29 | Airlite Plastics Co. | Concrete form with removable sidewall |
| CA3061942A1 (en) | 2018-11-19 | 2020-05-19 | Bradley J. Crosby | Concrete form with removable sidewall |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0526642T3 (da) * | 1991-01-29 | 1998-10-19 | Shionogi & Co | Triterpenderivat |
| ES2116663T3 (es) * | 1993-06-11 | 1998-07-16 | Shionogi & Co | Compuestos intermediarios para la preparacion de derivados triterpenos antagonistas del receptor de endotelina. |
| US5599811A (en) * | 1995-02-21 | 1997-02-04 | Warner-Lambert Company | Benzothiazine dioxides as endothelin antagonists |
-
1996
- 1996-05-29 TR TR97/01497T patent/TR199701497T1/xx unknown
- 1996-05-29 BR BR9608413A patent/BR9608413A/pt not_active Application Discontinuation
- 1996-05-29 AU AU58440/96A patent/AU700182B2/en not_active Ceased
- 1996-05-29 EP EP96919984A patent/EP0838223B1/de not_active Expired - Lifetime
- 1996-05-29 DK DK96919984T patent/DK0838223T3/da active
- 1996-05-29 PT PT96919984T patent/PT838223E/pt unknown
- 1996-05-29 AT AT96919984T patent/ATE245447T1/de not_active IP Right Cessation
- 1996-05-29 US US08/930,827 patent/US5945448A/en not_active Expired - Lifetime
- 1996-05-29 JP JP53636696A patent/JP4011114B2/ja not_active Expired - Fee Related
- 1996-05-29 ES ES96919984T patent/ES2202449T3/es not_active Expired - Lifetime
- 1996-05-29 WO PCT/JP1996/001438 patent/WO1996038173A1/ja not_active Ceased
- 1996-05-29 CA CA2218028A patent/CA2218028C/en not_active Expired - Fee Related
- 1996-05-29 DE DE69629195T patent/DE69629195T2/de not_active Expired - Lifetime
- 1996-05-29 CN CN96194363A patent/CN1083261C/zh not_active Expired - Fee Related
- 1996-05-29 KR KR1019970707867A patent/KR100399797B1/ko not_active Expired - Fee Related
- 1996-06-01 TW TW085106558A patent/TW460286B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69629195D1 (de) | 2003-08-28 |
| BR9608413A (pt) | 1998-12-29 |
| CA2218028C (en) | 2010-07-06 |
| JP4011114B2 (ja) | 2007-11-21 |
| DE69629195T2 (de) | 2004-05-06 |
| EP0838223A4 (de) | 2001-04-25 |
| AU700182B2 (en) | 1998-12-24 |
| KR100399797B1 (ko) | 2004-04-13 |
| EP0838223B1 (de) | 2003-07-23 |
| ES2202449T3 (es) | 2004-04-01 |
| CN1186441A (zh) | 1998-07-01 |
| EP0838223A1 (de) | 1998-04-29 |
| AU5844096A (en) | 1996-12-18 |
| US5945448A (en) | 1999-08-31 |
| KR19990008341A (ko) | 1999-01-25 |
| TW460286B (en) | 2001-10-21 |
| PT838223E (pt) | 2003-12-31 |
| DK0838223T3 (da) | 2003-11-17 |
| CA2218028A1 (en) | 1996-12-05 |
| WO1996038173A1 (en) | 1996-12-05 |
| TR199701497T1 (xx) | 1998-06-22 |
| MX9708920A (es) | 1998-03-31 |
| CN1083261C (zh) | 2002-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0838223 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |