ATE245699T1 - Rekombinant pgp3, verfahren zu dessen herstellung,und dessen verwendung in der diagnose und therapie - Google Patents
Rekombinant pgp3, verfahren zu dessen herstellung,und dessen verwendung in der diagnose und therapieInfo
- Publication number
- ATE245699T1 ATE245699T1 AT95915295T AT95915295T ATE245699T1 AT E245699 T1 ATE245699 T1 AT E245699T1 AT 95915295 T AT95915295 T AT 95915295T AT 95915295 T AT95915295 T AT 95915295T AT E245699 T1 ATE245699 T1 AT E245699T1
- Authority
- AT
- Austria
- Prior art keywords
- diagnosis
- therapy
- production
- pgp3
- recombinant
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 101100054302 Arabidopsis thaliana ABCB3 gene Proteins 0.000 title 1
- 101100113915 Arabidopsis thaliana CLS gene Proteins 0.000 title 1
- 101150063830 abcB4 gene Proteins 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 101100243724 Caenorhabditis elegans pgp-3 gene Proteins 0.000 abstract 1
- 241000606153 Chlamydia trachomatis Species 0.000 abstract 1
- 238000002965 ELISA Methods 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/229,980 US5629167A (en) | 1994-04-19 | 1994-04-19 | Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay |
| PCT/IB1995/000310 WO1995028487A2 (en) | 1994-04-19 | 1995-04-18 | Recombinant pgp3, methods of preparation and use in diagnosis and therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE245699T1 true ATE245699T1 (de) | 2003-08-15 |
Family
ID=22863480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95915295T ATE245699T1 (de) | 1994-04-19 | 1995-04-18 | Rekombinant pgp3, verfahren zu dessen herstellung,und dessen verwendung in der diagnose und therapie |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US5629167A (de) |
| EP (1) | EP0756630B1 (de) |
| JP (1) | JPH10503922A (de) |
| AT (1) | ATE245699T1 (de) |
| AU (1) | AU2222795A (de) |
| CA (1) | CA2188316A1 (de) |
| DE (1) | DE69531345T2 (de) |
| WO (1) | WO1995028487A2 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629167A (en) * | 1994-04-19 | 1997-05-13 | Biocine S.P.A. | Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay |
| US5944670A (en) * | 1996-12-02 | 1999-08-31 | Oridion Medical Ltd. | Breath test for the diagnosis of bacterial infection |
| US7459524B1 (en) * | 1997-10-02 | 2008-12-02 | Emergent Product Development Gaithersburg Inc. | Chlamydia protein, sequence and uses thereof |
| WO1999030737A1 (en) * | 1997-12-16 | 1999-06-24 | Chiron Corporation | Use of microparticles combined with submicron oil-in-water emulsions |
| US7393630B2 (en) * | 1997-12-16 | 2008-07-01 | Novartis Vaccines And Diagnostics, Inc. | Use of microparticles combined with submicron oil-in-water emulsions |
| CA2353107A1 (en) | 1998-12-01 | 2000-06-08 | Andrew D. Murdin | Chlamydia antigens and corresponding dna fragments and uses thereof |
| EP1169465B1 (de) * | 1998-12-04 | 2006-03-01 | University Of Manitoba | Zwei-schritte-verfahren zur impfung gegen chlamydia |
| US20020061848A1 (en) * | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| GB9828000D0 (en) * | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| US6919187B2 (en) * | 2000-04-21 | 2005-07-19 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| RU2331435C2 (ru) | 2001-12-12 | 2008-08-20 | Чирон Срл. | Иммунизация против chlamydia trachomatis |
| CN100374864C (zh) * | 2002-04-19 | 2008-03-12 | 再生生命工学会社 | 使用βig-h3蛋白质的诊断试剂盒 |
| DE10238825A1 (de) * | 2002-08-23 | 2004-03-11 | Roche Diagnostics Gmbh | Mikrofluidische Systeme mit hohem Aspektverhältnis |
| USD508479S1 (en) * | 2004-07-21 | 2005-08-16 | Matsushita Electric Industrial Co., Ltd. | Earphone with microphone |
| EP2152303A4 (de) * | 2007-05-01 | 2011-10-05 | Univ Texas | Chlamydien-antigene als reagentien zur diagnose und behandlung von chlamydien-infektion und erkrankung |
| AU2009302821A1 (en) | 2008-10-09 | 2010-04-15 | Board Of Regents, University Of Texas System | Methods and compositions for chlamydial antigens for diagnosis and treatment of chlamydial infection and disease |
| ITMI20090946A1 (it) | 2009-05-28 | 2010-11-29 | Novartis Ag | Espressione di proteine ricombinanti |
| WO2011112670A2 (en) * | 2010-03-09 | 2011-09-15 | Board Of Regents, University Of Texas System | Methods and compositions for chlamydial antigens for diagnosis and treatment of chlamydial infection and disease |
| WO2014113541A1 (en) * | 2013-01-16 | 2014-07-24 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Attenuated chlamydia vaccine |
| CN105126077A (zh) * | 2015-09-30 | 2015-12-09 | 侯淑萍 | 衣原体蛋白Pgp3在制备抑制银屑病样皮损药物中的应用 |
| CN109963864B (zh) * | 2016-08-11 | 2024-01-02 | 瑞普利金公司 | 用于亲和色谱的碱性稳定性fc结合蛋白 |
| EP3521304B9 (de) | 2018-02-01 | 2023-10-04 | Repligen Corporation | Fc-bindungsproteine mit cystein in der c-terminalen helikalen region |
| US11779860B2 (en) | 2017-08-07 | 2023-10-10 | Repligen Corporation | Fc binding proteins with cysteine in the C-terminal helical region |
| CN112345768B (zh) * | 2020-10-26 | 2021-05-07 | 华中农业大学 | 一种基于重组蛋白rsPgp3的家畜衣原体抗体的间接ELISA检测方法及试剂盒 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4336336A (en) | 1979-01-12 | 1982-06-22 | President And Fellows Of Harvard College | Fused gene and method of making and using same |
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| AU545912B2 (en) | 1980-03-10 | 1985-08-08 | Cetus Corporation | Cloned heterologous jive products in bacillies |
| ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
| NZ199722A (en) | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| US4551433A (en) | 1981-05-18 | 1985-11-05 | Genentech, Inc. | Microbial hybrid promoters |
| US4880911A (en) * | 1982-03-19 | 1989-11-14 | G. D. Searle & Co. | Fused polypeptides and methods for their detection |
| US4876197A (en) | 1983-02-22 | 1989-10-24 | Chiron Corporation | Eukaryotic regulatable transcription |
| CA1341302C (en) * | 1983-02-22 | 2001-10-09 | Rae Lyn Burke | Yeast expression systems with vectors having gapdh or pyk promoters and synthesis of foreign protein |
| JPS59166086A (ja) | 1983-03-09 | 1984-09-19 | Teruhiko Beppu | 新規な発現型プラスミドとそれらを用いて仔牛プロキモシン遺伝子を大腸菌内で発現させる方法 |
| US4546083A (en) | 1983-04-22 | 1985-10-08 | Stolle Research & Development Corporation | Method and device for cell culture growth |
| US4588684A (en) | 1983-04-26 | 1986-05-13 | Chiron Corporation | a-Factor and its processing signals |
| EP0127839B1 (de) | 1983-05-27 | 1992-07-15 | THE TEXAS A&M UNIVERSITY SYSTEM | Verfahren zur Herstellung eines rekombinanten Baculovirus-Expressionsvektors |
| US4689406A (en) | 1983-08-10 | 1987-08-25 | Amgen | Enhancement of microbial expression of polypeptides |
| US4870008A (en) | 1983-08-12 | 1989-09-26 | Chiron Corporation | Secretory expression in eukaryotes |
| JPS6054685A (ja) | 1983-09-02 | 1985-03-29 | Suntory Ltd | 改良発現ベクタ−およびその利用 |
| EP0136907A3 (de) | 1983-10-03 | 1986-12-30 | Genentech, Inc. | Xenogeneisches Expressionskontrollsystem, Verfahren zu dessen Verwendung, dieses enthaltende Expressionsvektoren, mit denselben transformierte Zellen und daraus hergestellte heterolose Proteine |
| ZA848495B (en) | 1984-01-31 | 1985-09-25 | Idaho Res Found | Production of polypeptides in insect cells |
| ATE102250T1 (de) | 1984-05-11 | 1994-03-15 | Chiron Corp | Erhoehte hefetranskription unter verwendung einer hybridkonstruktion der promotorregion. |
| US4880734A (en) | 1984-05-11 | 1989-11-14 | Chiron Corporation | Eukaryotic regulatable transcription |
| US4738921A (en) | 1984-09-27 | 1988-04-19 | Eli Lilly And Company | Derivative of the tryptophan operon for expression of fused gene products |
| US4745056A (en) | 1984-10-23 | 1988-05-17 | Biotechnica International, Inc. | Streptomyces secretion vector |
| US4837148A (en) | 1984-10-30 | 1989-06-06 | Phillips Petroleum Company | Autonomous replication sequences for yeast strains of the genus pichia |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| CA1260858A (en) | 1985-03-28 | 1989-09-26 | Lawrence S. Cousens | Expression using fused genes providing for protein product |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4865974A (en) | 1985-09-20 | 1989-09-12 | Cetus Corporation | Bacterial methionine N-terminal peptidase |
| JPS6296086A (ja) * | 1985-10-21 | 1987-05-02 | Agency Of Ind Science & Technol | 複合プラスミド |
| ES2061482T3 (es) | 1986-05-02 | 1994-12-16 | Gist Brocades Nv | Metodo para la identificacion de secuencias de señal secretora para sintesis de proteina extracelular en bacillus. |
| JPS63123383A (ja) | 1986-11-11 | 1988-05-27 | Mitsubishi Kasei Corp | ハイブリツドプロモ−タ−、発現調節dna配列および発現ベクタ− |
| CA1304020C (en) * | 1987-03-23 | 1992-06-23 | Meher H. Irani | High level expression in yeast |
| GB8709746D0 (en) * | 1987-04-24 | 1987-05-28 | Wenman W M | Chlamydia vaccine |
| US4929555A (en) | 1987-10-19 | 1990-05-29 | Phillips Petroleum Company | Pichia transformation |
| US4800734A (en) | 1987-11-02 | 1989-01-31 | White Consolidated Industries, Inc. | Room air conditioner |
| CA1340772C (en) * | 1987-12-30 | 1999-09-28 | Patricia Tekamp-Olson | Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences |
| US4973551A (en) * | 1988-01-15 | 1990-11-27 | Merck & Co., Inc. | Vector for the expression of fusion proteins and protein immunogens |
| IT1224253B (it) * | 1988-04-08 | 1990-09-26 | Sclavo Spa | Oligonucleotidi sintetici utili per la determinazione di chlamydia trachomatis in un campione biologico |
| CA2017507C (en) * | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
| FR2659578B1 (fr) * | 1990-03-14 | 1995-04-28 | Peugeot | Appareil d'alimentation automatique en flans de tole d'une presse ou autre machine quelconque. |
| IT1244706B (it) * | 1991-02-07 | 1994-08-08 | Sclavo Spa | Plasmide pctd isolato da chlamydia trachomatis serotipo d, suoi geni e proteine da essi codificate; plasmidi ricombinanti per l'espressionedi detti geni in sistemi eterologhi come proteine ricombinanti di fusione, preparazione di dette proteine ricombinanti e loro uso nella formulazione di vaccini e/o diagnostici |
| US6248563B1 (en) * | 1991-02-07 | 2001-06-19 | Scalvo Spa | Chlamydia trachomatis serotype D genes |
| US5629167A (en) * | 1994-04-19 | 1997-05-13 | Biocine S.P.A. | Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay |
| US6448234B1 (en) * | 1998-12-08 | 2002-09-10 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20020061848A1 (en) * | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| WO2001081379A2 (en) * | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US6919187B2 (en) * | 2000-04-21 | 2005-07-19 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| RU2331435C2 (ru) * | 2001-12-12 | 2008-08-20 | Чирон Срл. | Иммунизация против chlamydia trachomatis |
| US7105171B2 (en) * | 2002-03-07 | 2006-09-12 | The Regents Of The University Of California | Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia |
-
1994
- 1994-04-19 US US08/229,980 patent/US5629167A/en not_active Expired - Lifetime
-
1995
- 1995-04-18 CA CA002188316A patent/CA2188316A1/en not_active Abandoned
- 1995-04-18 JP JP7526847A patent/JPH10503922A/ja active Pending
- 1995-04-18 DE DE69531345T patent/DE69531345T2/de not_active Expired - Lifetime
- 1995-04-18 WO PCT/IB1995/000310 patent/WO1995028487A2/en not_active Ceased
- 1995-04-18 AU AU22227/95A patent/AU2222795A/en not_active Abandoned
- 1995-04-18 AT AT95915295T patent/ATE245699T1/de active
- 1995-04-18 EP EP95915295A patent/EP0756630B1/de not_active Expired - Lifetime
- 1995-06-05 US US08/465,465 patent/US6210968B1/en not_active Expired - Fee Related
-
1998
- 1998-01-23 US US09/012,716 patent/US6649374B1/en not_active Expired - Fee Related
-
2003
- 2003-02-13 US US10/365,602 patent/US7070791B2/en not_active Expired - Fee Related
-
2006
- 2006-03-17 US US11/377,566 patent/US7485313B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6649374B1 (en) | 2003-11-18 |
| CA2188316A1 (en) | 1995-10-26 |
| AU2222795A (en) | 1995-11-10 |
| EP0756630B1 (de) | 2003-07-23 |
| DE69531345D1 (de) | 2003-08-28 |
| EP0756630A1 (de) | 1997-02-05 |
| US7070791B2 (en) | 2006-07-04 |
| US20060147474A1 (en) | 2006-07-06 |
| DE69531345T2 (de) | 2004-04-15 |
| WO1995028487A2 (en) | 1995-10-26 |
| US7485313B2 (en) | 2009-02-03 |
| US5629167A (en) | 1997-05-13 |
| JPH10503922A (ja) | 1998-04-14 |
| WO1995028487A3 (en) | 1995-12-28 |
| US6210968B1 (en) | 2001-04-03 |
| US20040053393A1 (en) | 2004-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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