ATE247462T1 - Verwendung von metformin gegen die gewichtszunahme, die mit valproat und andere psychotropische arzneimittel verbunden ist - Google Patents

Verwendung von metformin gegen die gewichtszunahme, die mit valproat und andere psychotropische arzneimittel verbunden ist

Info

Publication number: ATE247462T1
Authority: AT; Austria
Prior art keywords: valproate; metformin; weight gain; gain associated; psychotropic drugs
Prior art date: 1998-10-15

Application number

AT99952021T

Other languages

English (en)

Inventor

Elizabeth Marie Cottingham

Original Assignee

Cottingham Elizabeth M

Morrison John A

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-15

Filing date

1999-10-15

Publication date

2003-09-15

1999-10-15 Application filed by Cottingham Elizabeth M, Morrison John A filed Critical Cottingham Elizabeth M

2003-09-15 Application granted granted Critical

2003-09-15 Publication of ATE247462T1 publication Critical patent/ATE247462T1/de

Links

AEQFSUDEHCCHBT-UHFFFAOYSA-M sodium valproate Chemical compound [Na+].CCCC(C([O-])=O)CCC AEQFSUDEHCCHBT-UHFFFAOYSA-M 0.000 title abstract 4
229940102566 valproate Drugs 0.000 title abstract 4
XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 3
229960003105 metformin Drugs 0.000 title abstract 3
230000004584 weight gain Effects 0.000 title abstract 2
235000019786 weight gain Nutrition 0.000 title abstract 2
229940001470 psychoactive drug Drugs 0.000 title 1
239000004089 psychotropic agent Substances 0.000 title 1
238000000034 method Methods 0.000 abstract 2
229940123208 Biguanide Drugs 0.000 abstract 1
-1 biguanide compound Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Child & Adolescent Psychology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT99952021T 1998-10-15 1999-10-15 Verwendung von metformin gegen die gewichtszunahme, die mit valproat und andere psychotropische arzneimittel verbunden ist ATE247462T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US10439498P	1998-10-15	1998-10-15
US09/416,330 US6194466B1 (en)	1998-10-15	1999-10-12	Use of metformin to counteract weight gain associated with valproate and other psychotropic medications
PCT/US1999/024262 WO2000021522A1 (en)	1998-10-15	1999-10-15	Use of metformin to counteract weight gain associated with valproate and other psychotropic medications

Publications (1)

Publication Number	Publication Date
ATE247462T1 true ATE247462T1 (de)	2003-09-15

Family

ID=26801492

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99952021T ATE247462T1 (de)	1998-10-15	1999-10-15	Verwendung von metformin gegen die gewichtszunahme, die mit valproat und andere psychotropische arzneimittel verbunden ist

Country Status (6)

Country	Link
US (1)	US6194466B1 (de)
EP (1)	EP1121110B1 (de)
AT (1)	ATE247462T1 (de)
AU (1)	AU6432899A (de)
DE (1)	DE69910600T2 (de)
WO (1)	WO2000021522A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4167742B2 (ja) *	1998-01-23	2008-10-22	中央発條株式会社	押し引きコントロールケーブル
US20050171088A1 (en) *	2004-01-30	2005-08-04	Astrazeneca Ab	Treatment of psychoses with dibenzothiazepine antipsychotic
US20060246131A1 (en) *	2005-04-28	2006-11-02	Cottlingham Elizabeth M	Use of metformin to counteract weight gain associated with psychotropic medications
WO2008090534A1 (en) *	2007-01-26	2008-07-31	Berand Limited	Methods and compositions for inhibition of excessive weight gain, reduction of inappropriate eating behaviours and inhibition of binge eating for the treatment of obesity
WO2017023833A1 (en)	2015-08-01	2017-02-09	Petti Stephen J	Compositions and methods for combination pharmacological treatments to induce a prolonged, mild decrease in core body temperature
WO2020037326A1 (en) *	2018-08-17	2020-02-20	Frequency Therapeutics, Inc.	Compositions and methods for generating hair cells by downregulating foxo
CA3109647A1 (en)	2018-08-17	2020-02-20	Frequency Therapeutics, Inc.	Compositions and methods for generating hair cells by upregulating jag-1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4432757A1 (de) *	1994-09-14	1996-03-21	Boehringer Mannheim Gmbh	Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung

1999
- 1999-10-12 US US09/416,330 patent/US6194466B1/en not_active Expired - Lifetime
- 1999-10-15 DE DE69910600T patent/DE69910600T2/de not_active Expired - Lifetime
- 1999-10-15 AU AU64328/99A patent/AU6432899A/en not_active Abandoned
- 1999-10-15 WO PCT/US1999/024262 patent/WO2000021522A1/en not_active Ceased
- 1999-10-15 EP EP99952021A patent/EP1121110B1/de not_active Expired - Lifetime
- 1999-10-15 AT AT99952021T patent/ATE247462T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69910600T2 (de)	2004-06-24
AU6432899A (en)	2000-05-01
DE69910600D1 (de)	2003-09-25
EP1121110A1 (de)	2001-08-08
WO2000021522A1 (en)	2000-04-20
EP1121110B1 (de)	2003-08-20
US6194466B1 (en)	2001-02-27

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Legal Events

Date	Code	Title	Description
2004-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties