ATE247710T1 - Genexpression von utrophin - Google Patents

Genexpression von utrophin

Info

Publication number
ATE247710T1
ATE247710T1 AT96942508T AT96942508T ATE247710T1 AT E247710 T1 ATE247710 T1 AT E247710T1 AT 96942508 T AT96942508 T AT 96942508T AT 96942508 T AT96942508 T AT 96942508T AT E247710 T1 ATE247710 T1 AT E247710T1
Authority
AT
Austria
Prior art keywords
utrophin
nucleic acid
gene expression
actin
severity
Prior art date
Application number
AT96942508T
Other languages
English (en)
Inventor
Jonathon Mark Tinsley
Kay Elizabeth Davies
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9525962.8A external-priority patent/GB9525962D0/en
Priority claimed from GBGB9615797.9A external-priority patent/GB9615797D0/en
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of ATE247710T1 publication Critical patent/ATE247710T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4707—Muscular dystrophy
    • C07K14/4708—Duchenne dystrophy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96942508T 1995-12-19 1996-12-19 Genexpression von utrophin ATE247710T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9525962.8A GB9525962D0 (en) 1995-12-19 1995-12-19 Gene expression
GBGB9615797.9A GB9615797D0 (en) 1995-12-19 1996-07-26 Gene expression
GBGB9622174.2A GB9622174D0 (en) 1995-12-19 1996-10-24 Gene expression
PCT/GB1996/003156 WO1997022696A1 (en) 1995-12-19 1996-12-19 Utrophin gene expression

Publications (1)

Publication Number Publication Date
ATE247710T1 true ATE247710T1 (de) 2003-09-15

Family

ID=27268039

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96942508T ATE247710T1 (de) 1995-12-19 1996-12-19 Genexpression von utrophin

Country Status (10)

Country Link
US (1) US6518413B1 (de)
EP (1) EP0868511B1 (de)
JP (1) JP2000504931A (de)
AT (1) ATE247710T1 (de)
AU (1) AU724525B2 (de)
DE (1) DE69629586T2 (de)
DK (1) DK0868511T3 (de)
ES (1) ES2205070T3 (de)
GB (1) GB9622174D0 (de)
WO (1) WO1997022696A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9923423D0 (en) 1999-10-04 1999-12-08 Isis Innovation Promoting gene expression
WO2001083695A2 (en) 2000-04-28 2001-11-08 Xiao Xiao Dna sequences encoding dystrophin minigenes and methods of use thereof
GB2368064B (en) 2000-09-30 2002-11-13 Imp Cancer Res Tech DNA Element and Associated Protein
EP1366160B1 (de) * 2000-10-06 2008-07-09 The Regents Of The University Of Michigan Mini-dystrophin nukleinsäure- und peptidsequenzen
WO2005049850A2 (en) 2003-11-14 2005-06-02 University Of Washington Compositions and methods for systemic nucleic acid sequence delivery
US7771993B2 (en) * 2004-01-23 2010-08-10 The Trustees Of The University Of Pennsylvania Microutrophin and uses thereof
CA3099958A1 (en) * 2018-04-16 2019-10-24 The Trustees Of The University Of Pennsylvania Compositions and methods for treating duchenne muscular dystrophy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9408573D0 (en) * 1994-04-29 1994-06-22 Gatsby Charitable Foundation Identification, production and use of saponin gylcosyl hydrolases

Also Published As

Publication number Publication date
DE69629586T2 (de) 2004-06-24
EP0868511B1 (de) 2003-08-20
AU724525B2 (en) 2000-09-21
DE69629586D1 (de) 2003-09-25
AU1164497A (en) 1997-07-14
ES2205070T3 (es) 2004-05-01
US6518413B1 (en) 2003-02-11
WO1997022696A1 (en) 1997-06-26
EP0868511A1 (de) 1998-10-07
DK0868511T3 (da) 2003-12-08
JP2000504931A (ja) 2000-04-25
GB9622174D0 (en) 1996-12-18

Similar Documents

Publication Publication Date Title
EP0804609A4 (de) NEUARTIGE AUF p53 ANSPRECHENDE GENE
AU682140B2 (en) Multidrug resistance gene
EP0523140A4 (en) Reagents and methods for modulating gene expression through rna mimicry
CA2294516A1 (en) Ikk-.beta. proteins, nucleic acids and methods
WO2000053722A3 (en) Delivery of nucleic acids and proteins to cells
NZ191278A (en) Dna transfer vector comprising nucleotide sequence coding for eukaryotic protein and prokaryotic control fragment micro-organisms transformed proteins synthesised using microorganisms
EP0585257A4 (de) Für natürliche killerzellen spezifische dna- und aminosäuresequenz.
WO1995009872B1 (en) Dna encoding prostaglandin receptor ip
WO1998021343A8 (en) Genes encoding telomerase proteins
NO910982D0 (no) Uratoksydase-aktivt protein, rekombinant gen som koder for det, ekspresjonsvektor, mikroorganismer og transformerteceller.
EE200000151A (et) Aminoterminaalselt kärbitud rantes vormid, DNA molekulid, ekspressioonivektor, peremeesrakk, rekombinantne meetod proteiini valmistamiseks, proteiini kasutamine ning farmatseutiline kompositsioon
WO1998008961A3 (en) Endosperm and nucellus specific genes, promoters and uses thereof
WO1996007739A3 (en) Interleukin-1 type 3 receptors
DE69629586D1 (de) Genexpression von utrophin
CA2173102A1 (en) Dna sequence coding for a bmp receptor
DE69637599D1 (de) Rezeptoren für das humane Interleukin-12
HUP9900750A2 (hu) Gén kifejezésére szolgáló promóterek
CA2336261A1 (en) Cyclin e2 genes and proteins
CA2294566A1 (en) Ikk-.alpha. proteins, nucleic acids and methods
FR2732346B1 (fr) Proteines mutees, codees par un gene env mute de lentivirus, fragments peptidiques inclus dans lesdites proteines, vecteurs d'expression exprimant lesdites proteines mutees et leurs applications
ATE202570T1 (de) Gene, die für macif proteine kodieren, expressionsvektoren mit diesem genen, und transformantenzellen mit diesem proteinen
AU4375493A (en) Isolated protein receptors, antibodies which bind thereto, nucleic acid sequence coding therefor, and uses thereof
CA2032167A1 (en) Dna coding for protein binds to enhancer of.alpha.-fetoprotein gene
EP0155832A3 (de) Stabile Proteine, Verfahren zu deren Herstellung, dieselben kodierende Plasmide und andere DNS, diese Plasmide enthaltende Zellkulturen
WO1999022005A3 (en) Heparan sulfate d-glucosaminyl 3-o-sulfotransferases, an uses therefor

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties