ATE247710T1 - Genexpression von utrophin - Google Patents

Genexpression von utrophin

Info

Publication number
ATE247710T1
ATE247710T1 AT96942508T AT96942508T ATE247710T1 AT E247710 T1 ATE247710 T1 AT E247710T1 AT 96942508 T AT96942508 T AT 96942508T AT 96942508 T AT96942508 T AT 96942508T AT E247710 T1 ATE247710 T1 AT E247710T1
Authority
AT
Austria
Prior art keywords
utrophin
nucleic acid
gene expression
actin
severity
Prior art date
Application number
AT96942508T
Other languages
English (en)
Inventor
Jonathon Mark Tinsley
Kay Elizabeth Davies
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9525962.8A external-priority patent/GB9525962D0/en
Priority claimed from GBGB9615797.9A external-priority patent/GB9615797D0/en
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of ATE247710T1 publication Critical patent/ATE247710T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4707Muscular dystrophy
    • C07K14/4708Duchenne dystrophy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT96942508T 1995-12-19 1996-12-19 Genexpression von utrophin ATE247710T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9525962.8A GB9525962D0 (en) 1995-12-19 1995-12-19 Gene expression
GBGB9615797.9A GB9615797D0 (en) 1995-12-19 1996-07-26 Gene expression
GBGB9622174.2A GB9622174D0 (en) 1995-12-19 1996-10-24 Gene expression
PCT/GB1996/003156 WO1997022696A1 (en) 1995-12-19 1996-12-19 Utrophin gene expression

Publications (1)

Publication Number Publication Date
ATE247710T1 true ATE247710T1 (de) 2003-09-15

Family

ID=27268039

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96942508T ATE247710T1 (de) 1995-12-19 1996-12-19 Genexpression von utrophin

Country Status (10)

Country Link
US (1) US6518413B1 (de)
EP (1) EP0868511B1 (de)
JP (1) JP2000504931A (de)
AT (1) ATE247710T1 (de)
AU (1) AU724525B2 (de)
DE (1) DE69629586T2 (de)
DK (1) DK0868511T3 (de)
ES (1) ES2205070T3 (de)
GB (1) GB9622174D0 (de)
WO (1) WO1997022696A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9923423D0 (en) 1999-10-04 1999-12-08 Isis Innovation Promoting gene expression
ES2330615T3 (es) 2000-04-28 2009-12-14 Asklepios Biopharmaceutical, Inc. Secuencias de adn que codifican para minigenes de distrofina y metodos de uso de las mismas.
GB2368064B (en) 2000-09-30 2002-11-13 Imp Cancer Res Tech DNA Element and Associated Protein
EP1366160B1 (de) * 2000-10-06 2008-07-09 The Regents Of The University Of Michigan Mini-dystrophin nukleinsäure- und peptidsequenzen
US7655467B2 (en) 2003-11-14 2010-02-02 The University Of Washington Compositions and methods for systemic nucleic acid sequence delivery
US7771993B2 (en) * 2004-01-23 2010-08-10 The Trustees Of The University Of Pennsylvania Microutrophin and uses thereof
US12460226B2 (en) 2018-04-16 2025-11-04 The Trustees Of The University Of Pennsylvania Compositions and methods for treating duchenne muscular dystrophy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9408573D0 (en) * 1994-04-29 1994-06-22 Gatsby Charitable Foundation Identification, production and use of saponin gylcosyl hydrolases

Also Published As

Publication number Publication date
DK0868511T3 (da) 2003-12-08
AU1164497A (en) 1997-07-14
ES2205070T3 (es) 2004-05-01
WO1997022696A1 (en) 1997-06-26
US6518413B1 (en) 2003-02-11
EP0868511A1 (de) 1998-10-07
DE69629586T2 (de) 2004-06-24
GB9622174D0 (en) 1996-12-18
JP2000504931A (ja) 2000-04-25
AU724525B2 (en) 2000-09-21
DE69629586D1 (de) 2003-09-25
EP0868511B1 (de) 2003-08-20

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