ATE247978T1 - Verwendung von ompa enterobakterproteinen um zielgerichtet antigen-präsentierende zellen anzusteuern - Google Patents

Verwendung von ompa enterobakterproteinen um zielgerichtet antigen-präsentierende zellen anzusteuern

Info

Publication number: ATE247978T1
Authority: AT; Austria
Prior art keywords: ompa; presenting cells; targe; enterobacter; proteins
Prior art date: 1998-11-06

Application number

AT99971719T

Other languages

English (en)

Inventor

Jean-Yves Bonnefoy

Sybille Lecoanet

Jean-Pierre Aubry

Pascale Jeannin

Thierry Baussant

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-06

Filing date

1999-11-08

Publication date

2003-09-15

1999-11-08 Application filed by Pf Medicament filed Critical Pf Medicament

2003-09-15 Application granted granted Critical

2003-09-15 Publication of ATE247978T1 publication Critical patent/ATE247978T1/de

Links

210000000612 antigen-presenting cell Anatomy 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
102000004169 proteins and genes Human genes 0.000 title abstract 2
241000588914 Enterobacter Species 0.000 title 1
SZKKRCSOSQAJDE-UHFFFAOYSA-N Schradan Chemical compound CN(C)P(=O)(N(C)C)OP(=O)(N(C)C)N(C)C SZKKRCSOSQAJDE-UHFFFAOYSA-N 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 2
108010079246 OMPA outer membrane proteins Proteins 0.000 abstract 2
208000023275 Autoimmune disease Diseases 0.000 abstract 1
208000035473 Communicable disease Diseases 0.000 abstract 1
241000588747 Klebsiella pneumoniae Species 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
229940088623 biologically active substance Drugs 0.000 abstract 1
210000004443 dendritic cell Anatomy 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000008685 targeting Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT99971719T 1998-11-06 1999-11-08 Verwendung von ompa enterobakterproteinen um zielgerichtet antigen-präsentierende zellen anzusteuern ATE247978T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9814007A FR2785542B1 (fr)	1998-11-06	1998-11-06	UTILISATION D'UNE PROTEINE OmpA D'ENTEROBACTERIE, POUR LE CIBLAGE SPECIFIQUE D'UNE SUBSTANCE BIOLOGIQUEMENT ACTIVE QUI LUI EST ASSOCIEE VERS LES CELLULES PRESENTATRICES D'ANTIGENES TELLES QUE LES CELLULES DENDRITIQUES HUMAINES
PCT/FR1999/002734 WO2000027432A1 (fr)	1998-11-06	1999-11-08	UTILISATION D'UNE PROTEINE OmpA D'ENTEROBACTERIE, POUR LE CIBLAGE SPECIFIQUE VERS LES CELLULES PRESENTATRICES D'ANTIGENES

Publications (1)

Publication Number	Publication Date
ATE247978T1 true ATE247978T1 (de)	2003-09-15

Family

ID=9532467

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99971719T ATE247978T1 (de)	1998-11-06	1999-11-08	Verwendung von ompa enterobakterproteinen um zielgerichtet antigen-präsentierende zellen anzusteuern

Country Status (14)

Country	Link
EP (1)	EP1124577B1 (de)
JP (1)	JP2002529428A (de)
CN (1)	CN1181890C (de)
AT (1)	ATE247978T1 (de)
AU (1)	AU764205B2 (de)
BR (1)	BR9915071A (de)
CA (1)	CA2350183A1 (de)
DE (1)	DE69910809T2 (de)
DK (1)	DK1124577T3 (de)
ES (1)	ES2205946T3 (de)
FR (1)	FR2785542B1 (de)
PT (1)	PT1124577E (de)
WO (1)	WO2000027432A1 (de)
ZA (1)	ZA200103478B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2790959B1 (fr) *	1999-03-15	2003-06-27	Pf Medicament	Utilisation de fractions membranaires bacteriennes a effet adjuvant, leurs procedes de preparation et composition pharmaceutique les contenant
FR2790960B1 (fr) *	1999-03-15	2002-10-31	Pf Medicament	Utilisation de fractions membranaires bacteriennes a activite immunostimulante dans le traitement de cancers, leurs procedes de preparation et les compositions pharmaceutiques les contenant
WO2001013948A1 (en) *	1999-08-20	2001-03-01	The General Hospital Corporation	Outer membrane protein a, peptidoglycan-associated lipoprotein, and murein lipoprotein as therapeutic targets for treatment of sepsis
FR2803302B1 (fr) *	2000-01-04	2004-12-10	Pf Medicament	Procede de preparation d'un polypeptide soluble en solvant aqueux en absence de detergent
FR2809014A1 (fr) *	2000-05-16	2001-11-23	Pf Medicament	Utilisation d'une proteine ompa d'enterobacterie comme agent antimicrobien
FR2822071B1 (fr) *	2001-03-15	2005-07-01	Pf Medicament	Utilisation d'une fraction membranaire de bacteries a gram negatif pour induire la maturation des cellules dendritiques
EP2377883A1 (de) *	2010-04-15	2011-10-19	Universite d'Auvergne Clermont I	Antagonisten zur Vorbeugung oder Behandlung von entzündlicher Darmerkrankung, speziell von Morbus Crohn
CN102286106B (zh) *	2011-07-11	2013-05-01	中国人民解放军军事医学科学院微生物流行病研究所	夹心外膜蛋白展示载体及应用其制备的大肠埃希菌疫苗
KR20170011221A (ko) *	2015-07-22	2017-02-02	이화여자대학교 산학협력단	클렙시엘라균 감염질환의 예방용 백신
KR102920415B1 (ko) *	2022-12-15	2026-02-02	충남대학교산학협력단	OmpA 단백질을 유효성분으로 포함하는 자가포식 활성 억제용 조성물
CN121426899B (zh) *	2025-12-30	2026-04-28	齐鲁工业大学(山东省科学院)	一种与肺炎克雷伯菌结合的结合蛋白b及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2726472B1 (fr) *	1994-11-07	1997-01-31	Pf Medicament	Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
US5853719A (en) *	1996-04-30	1998-12-29	Duke University	Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
FR2748476B1 (fr) *	1996-05-07	1998-08-14	Pf Medicament	Complexe immunogene, son utilisation, son procede de preparation et vaccin le contenant

1998
- 1998-11-06 FR FR9814007A patent/FR2785542B1/fr not_active Expired - Fee Related
1999
- 1999-11-08 CA CA002350183A patent/CA2350183A1/fr not_active Abandoned
- 1999-11-08 ES ES99971719T patent/ES2205946T3/es not_active Expired - Lifetime
- 1999-11-08 BR BR9915071-9A patent/BR9915071A/pt not_active IP Right Cessation
- 1999-11-08 AT AT99971719T patent/ATE247978T1/de not_active IP Right Cessation
- 1999-11-08 DE DE69910809T patent/DE69910809T2/de not_active Expired - Fee Related
- 1999-11-08 EP EP99971719A patent/EP1124577B1/de not_active Expired - Lifetime
- 1999-11-08 AU AU11641/00A patent/AU764205B2/en not_active Ceased
- 1999-11-08 JP JP2000580661A patent/JP2002529428A/ja not_active Withdrawn
- 1999-11-08 PT PT99971719T patent/PT1124577E/pt unknown
- 1999-11-08 CN CNB998134538A patent/CN1181890C/zh not_active Expired - Fee Related
- 1999-11-08 WO PCT/FR1999/002734 patent/WO2000027432A1/fr not_active Ceased
- 1999-11-08 DK DK99971719T patent/DK1124577T3/da active
2001
- 2001-04-30 ZA ZA200103478A patent/ZA200103478B/en unknown

Also Published As

Publication number	Publication date
CN1181890C (zh)	2004-12-29
CA2350183A1 (fr)	2000-05-18
PT1124577E (pt)	2004-01-30
ZA200103478B (en)	2002-02-12
ES2205946T3 (es)	2004-05-01
AU1164100A (en)	2000-05-29
DK1124577T3 (da)	2003-12-08
WO2000027432A1 (fr)	2000-05-18
JP2002529428A (ja)	2002-09-10
CN1326360A (zh)	2001-12-12
EP1124577B1 (de)	2003-08-27
DE69910809T2 (de)	2004-06-17
FR2785542A1 (fr)	2000-05-12
EP1124577A1 (de)	2001-08-22
AU764205B2 (en)	2003-08-14
DE69910809D1 (de)	2003-10-02
FR2785542B1 (fr)	2001-02-09
BR9915071A (pt)	2001-07-17

Legal Events

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2004-08-15

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Publication of translation of european patent specification

Ref document number: 1124577

Country of ref document: EP

2007-08-15

REN

Ceased due to non-payment of the annual fee

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