ATE249476T1 - Cyclin d1 und seine cdna - Google Patents
Cyclin d1 und seine cdnaInfo
- Publication number
- ATE249476T1 ATE249476T1 AT92909340T AT92909340T ATE249476T1 AT E249476 T1 ATE249476 T1 AT E249476T1 AT 92909340 T AT92909340 T AT 92909340T AT 92909340 T AT92909340 T AT 92909340T AT E249476 T1 ATE249476 T1 AT E249476T1
- Authority
- AT
- Austria
- Prior art keywords
- prad1
- disclosed
- antibodies
- nucleic acid
- acid sequence
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0331—Animal model for proliferative diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/667,711 US6110700A (en) | 1991-03-11 | 1991-03-11 | PRAD1 cyclin and its cDNA |
| PCT/US1992/001925 WO1992015603A1 (en) | 1991-03-11 | 1992-03-11 | Prad1 cyclin and its cdna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE249476T1 true ATE249476T1 (de) | 2003-09-15 |
Family
ID=24679321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92909340T ATE249476T1 (de) | 1991-03-11 | 1992-03-11 | Cyclin d1 und seine cdna |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6110700A (de) |
| EP (1) | EP0575546B1 (de) |
| JP (1) | JP3369169B2 (de) |
| AT (1) | ATE249476T1 (de) |
| CA (1) | CA2104871C (de) |
| DE (1) | DE69233191T2 (de) |
| DK (1) | DK0575546T3 (de) |
| WO (1) | WO1992015603A1 (de) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6110700A (en) * | 1991-03-11 | 2000-08-29 | The General Hospital Corporation | PRAD1 cyclin and its cDNA |
| US6156876A (en) * | 1991-05-16 | 2000-12-05 | Cold Spring Harbor Laboratory | D-type cyclin and uses related thereto |
| US7550561B1 (en) * | 1991-05-16 | 2009-06-23 | Cold Spring Harbor Laboratory | p16INK4 polypeptides |
| US5543291A (en) * | 1993-01-29 | 1996-08-06 | Dana Farber Cancer Institute | Method of detecting carcinoma |
| US5514571A (en) * | 1993-08-05 | 1996-05-07 | University Technologies International Inc. | Cyclin D1 negative regulatory activity |
| US20020073441A1 (en) | 2000-12-13 | 2002-06-13 | Ross Brian D. | Compositions and methods for detecting proteolytic activity |
| US7226771B2 (en) | 2002-04-19 | 2007-06-05 | Diversa Corporation | Phospholipases, nucleic acids encoding them and methods for making and using them |
| EP1497418B1 (de) | 2002-04-19 | 2012-10-17 | Verenium Corporation | Phospholipasen, diese codierende nukleinsäuren sowie verfahren zu ihrer herstellung und verwendung |
| EP2194133B1 (de) | 2003-03-06 | 2015-12-02 | BASF Enzymes LLC | Amylasen, Nukleinsäuren, die diese codieren, und Verfahren zu deren Herstellung und Verwendung |
| CA2515583C (en) | 2003-03-07 | 2015-07-14 | Diversa Corporation | Hydrolases, nucleic acids encoding them and methods for making and using them |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| GB0307428D0 (en) * | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| EP1613733B1 (de) | 2003-04-04 | 2015-06-03 | BASF Enzymes LLC | Pektatlyasen, diese codierende nukleinsäuren und verfahren zu deren herstellung und verwendung |
| CN103484486B (zh) | 2003-07-02 | 2018-04-24 | 维莱尼姆公司 | 葡聚糖酶,编码它们的核酸以及制备和使用它们的方法 |
| US7741089B2 (en) | 2003-08-11 | 2010-06-22 | Verenium Corporation | Laccases, nucleic acids encoding them and methods for making and using them |
| US20050221339A1 (en) * | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| AU2005264938B2 (en) | 2004-06-16 | 2011-11-24 | Verenium Corporation | Compositions and methods for enzymatic decolorization of chlorophyll |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| EP1869174B1 (de) | 2005-03-10 | 2015-02-18 | BASF Enzymes LLC | Lyase-enzyme, nukleinsäuren zu deren kodierung und verfahren zu deren herstellung und verwendung |
| EA018577B1 (ru) | 2005-03-15 | 2013-09-30 | Верениум Корпорейшн | Целлюлазы, нуклеиновые кислоты, кодирующие их, и способы их получения и применения |
| WO2007081385A2 (en) | 2006-01-11 | 2007-07-19 | Raindance Technologies, Inc. | Microfluidic devices and methods of use in the formation and control of nanoreactors |
| EP1987142A4 (de) | 2006-02-02 | 2009-07-15 | Verenium Corp | Esterasen und damit zusammenhängende nukleinsäuren und verfahren |
| NZ595502A (en) | 2006-02-10 | 2013-11-29 | Verenium Corp | Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them |
| ES2682284T3 (es) | 2006-02-14 | 2018-09-19 | Bp Corporation North America Inc. | Xilanasas, ácidos nucleicos que las codifican y métodos para elaborarlas y usarlas |
| KR101622894B1 (ko) | 2006-03-07 | 2016-05-19 | 바스프 엔자임스 엘엘씨 | 알돌라제, 이것을 코딩하는 핵산과 그 제조 방법 및 사용 방법 |
| ES2416104T3 (es) | 2006-03-07 | 2013-07-30 | Cargill, Incorporated | Aldolasas, ácidos nucleicos que las codifican y métodos para producir y usar las mismas |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| WO2007133710A2 (en) | 2006-05-11 | 2007-11-22 | Raindance Technologies, Inc. | Microfluidic devices and methods of use thereof |
| CN106222185B (zh) | 2006-08-04 | 2021-12-03 | 维莱尼姆公司 | 葡聚糖酶、编码它们的核酸及制备和使用它们的方法 |
| US9012390B2 (en) | 2006-08-07 | 2015-04-21 | Raindance Technologies, Inc. | Fluorocarbon emulsion stabilizing surfactants |
| EP2057274B1 (de) | 2006-09-21 | 2013-12-11 | DSM IP Assets B.V. | Phospholipase ,nukleinsaüre, die diese kodieren und verfahren zur ihrer herstellung und verwendung |
| US8877478B2 (en) | 2006-09-21 | 2014-11-04 | Verenium Corporation | Phytases, nucleic acids encoding them and methods for making and using them |
| PL3101128T3 (pl) | 2006-12-21 | 2019-09-30 | Basf Enzymes Llc | Amylazy i glukoamylazy, kwasy nukleinowe kodujące te związki oraz sposoby wytwarzania tych związków oraz stosowania ich |
| WO2008097559A2 (en) | 2007-02-06 | 2008-08-14 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| NZ601191A (en) | 2007-10-03 | 2014-01-31 | Verenium Corp | Xylanases, nucleic acids encoding them and methods for making and using them |
| CA2739011A1 (en) * | 2007-10-29 | 2009-05-07 | The Regents Of The University Of California | Osteoarthritis gene therapy |
| CA2710922A1 (en) | 2008-01-03 | 2009-07-16 | Verenium Corporation | Isomerases, nucleic acids encoding them and methods for making and using them |
| AU2008347234B2 (en) | 2008-01-03 | 2015-05-28 | Basf Enzymes Llc | Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them |
| EP4047367A1 (de) | 2008-07-18 | 2022-08-24 | Bio-Rad Laboratories, Inc. | Verfahren zum nachweis von zielanalyten unter verwendung von tropfenbibliotheken |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| US8357503B2 (en) | 2008-08-29 | 2013-01-22 | Bunge Oils, Inc. | Hydrolases, nucleic acids encoding them and methods for making and using them |
| US8153391B2 (en) | 2008-08-29 | 2012-04-10 | Bunge Oils, Inc. | Hydrolases, nucleic acids encoding them and methods for making and using them |
| US8198062B2 (en) | 2008-08-29 | 2012-06-12 | Dsm Ip Assets B.V. | Hydrolases, nucleic acids encoding them and methods for making and using them |
| AU2009290563A1 (en) | 2008-09-15 | 2010-03-18 | Genentech, Inc. | Compositions and methods for regulating cell osmolarity |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| HUE030948T2 (en) | 2009-05-21 | 2017-06-28 | Basf Enzymes Llc | Phytases, nucleic acids and processes encoding them for their production and use |
| US10520500B2 (en) | 2009-10-09 | 2019-12-31 | Abdeslam El Harrak | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| UA111708C2 (uk) | 2009-10-16 | 2016-06-10 | Бандж Ойлз, Інк. | Спосіб рафінування олії |
| UA109884C2 (uk) | 2009-10-16 | 2015-10-26 | Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування | |
| EP2517025B1 (de) | 2009-12-23 | 2019-11-27 | Bio-Rad Laboratories, Inc. | Verfahren zur reduzierung des austauschs von molekülen zwischen tröpfchen |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| EP4435111A1 (de) | 2010-02-12 | 2024-09-25 | Bio-Rad Laboratories, Inc. | Digitale analytanalyse |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| EP3859011A1 (de) | 2011-02-11 | 2021-08-04 | Bio-Rad Laboratories, Inc. | Verfahren zur bildung gemischter tröpfchen |
| WO2012112804A1 (en) | 2011-02-18 | 2012-08-23 | Raindance Technoligies, Inc. | Compositions and methods for molecular labeling |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| EP2714970B1 (de) | 2011-06-02 | 2017-04-19 | Raindance Technologies, Inc. | Enzymquantifizierung |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| US20130210659A1 (en) | 2012-02-10 | 2013-08-15 | Andrew Watson | Molecular diagnostic screening assay |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| EP2986762B1 (de) | 2013-04-19 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Digitale analyse von analyten |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| US20220348919A1 (en) * | 2017-01-18 | 2022-11-03 | Centre National De La Recherche Scientifique | Hybrid nucleic acid molecules and their use |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4535058A (en) * | 1982-10-01 | 1985-08-13 | Massachusetts Institute Of Technology | Characterization of oncogenes and assays based thereon |
| NZ212291A (en) * | 1984-06-08 | 1991-10-25 | Suntory Ltd | Peptide from human atrium cordis having diuretic action, dna coding therefor and pharmaceutical compositions thereof |
| US6110700A (en) * | 1991-03-11 | 2000-08-29 | The General Hospital Corporation | PRAD1 cyclin and its cDNA |
| US5538846A (en) * | 1992-09-17 | 1996-07-23 | Meeker; Timothy C. | BCL-1 locus nucleic acid probes and assay methods |
-
1991
- 1991-03-11 US US07/667,711 patent/US6110700A/en not_active Expired - Lifetime
-
1992
- 1992-03-11 DE DE69233191T patent/DE69233191T2/de not_active Expired - Fee Related
- 1992-03-11 DK DK92909340T patent/DK0575546T3/da active
- 1992-03-11 JP JP50891192A patent/JP3369169B2/ja not_active Expired - Lifetime
- 1992-03-11 WO PCT/US1992/001925 patent/WO1992015603A1/en not_active Ceased
- 1992-03-11 AT AT92909340T patent/ATE249476T1/de not_active IP Right Cessation
- 1992-03-11 CA CA002104871A patent/CA2104871C/en not_active Expired - Lifetime
- 1992-03-11 EP EP92909340A patent/EP0575546B1/de not_active Expired - Lifetime
-
1995
- 1995-06-02 US US08/460,744 patent/US6107541A/en not_active Expired - Lifetime
- 1995-06-02 US US08/460,694 patent/US5858655A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992015603A1 (en) | 1992-09-17 |
| US6110700A (en) | 2000-08-29 |
| US6107541A (en) | 2000-08-22 |
| CA2104871C (en) | 2009-12-22 |
| DE69233191D1 (de) | 2003-10-16 |
| EP0575546A4 (en) | 1996-04-03 |
| US5858655A (en) | 1999-01-12 |
| CA2104871A1 (en) | 1992-09-12 |
| DE69233191T2 (de) | 2004-06-17 |
| JP3369169B2 (ja) | 2003-01-20 |
| EP0575546A1 (de) | 1993-12-29 |
| EP0575546B1 (de) | 2003-09-10 |
| DK0575546T3 (da) | 2004-01-26 |
| JPH06505398A (ja) | 1994-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |