ATE250619T1 - Verfahren zur herstellung von sphingosinen und ceramide im grossmassstab - Google Patents

Verfahren zur herstellung von sphingosinen und ceramide im grossmassstab

Info

Publication number
ATE250619T1
ATE250619T1 AT00922837T AT00922837T ATE250619T1 AT E250619 T1 ATE250619 T1 AT E250619T1 AT 00922837 T AT00922837 T AT 00922837T AT 00922837 T AT00922837 T AT 00922837T AT E250619 T1 ATE250619 T1 AT E250619T1
Authority
AT
Austria
Prior art keywords
ceramides
large scale
sphingosins
producing
sphingosines
Prior art date
Application number
AT00922837T
Other languages
English (en)
Inventor
Elimelech Rochlin
Original Assignee
Lipiderm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipiderm Ltd filed Critical Lipiderm Ltd
Application granted granted Critical
Publication of ATE250619T1 publication Critical patent/ATE250619T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/08Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/16Preparation of optical isomers
    • C07C231/18Preparation of optical isomers by stereospecific synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT00922837T 1999-05-10 2000-05-09 Verfahren zur herstellung von sphingosinen und ceramide im grossmassstab ATE250619T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13352699P 1999-05-10 1999-05-10
PCT/IL2000/000264 WO2000068238A1 (en) 1999-05-10 2000-05-09 Process for large scale preparation of sphingosines and ceramides

Publications (1)

Publication Number Publication Date
ATE250619T1 true ATE250619T1 (de) 2003-10-15

Family

ID=22459033

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00922837T ATE250619T1 (de) 1999-05-10 2000-05-09 Verfahren zur herstellung von sphingosinen und ceramide im grossmassstab

Country Status (9)

Country Link
US (1) US6469148B1 (de)
EP (1) EP1187839B1 (de)
JP (1) JP2002544135A (de)
AT (1) ATE250619T1 (de)
AU (1) AU770635B2 (de)
CA (1) CA2373286C (de)
DE (1) DE60005513T2 (de)
IL (1) IL146120A0 (de)
WO (1) WO2000068238A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10325829A1 (de) 2003-06-06 2004-12-30 Asc Biotech Gmbh Derivate natürlicher, halbsynthetischer und syntetischer Lipide aus der Gruppe der Ceramide und der Sphingosine und ihre Verwendung als Therapeutica in der Medizin, speziell in der Dermatologie
EP2266950A1 (de) 2009-06-23 2010-12-29 Hans Uwe Wolf Ceramid-Dimere und ihre Verwendung als Arnzeimittel oder kosmetische Zubereitung
US20160208247A1 (en) 2013-07-31 2016-07-21 Qbi Enterprises Ltd. Methods of use of sphingolipid polyalkylamine oligonucleotide compounds
US9889200B2 (en) 2013-07-31 2018-02-13 Qbi Enterprises Ltd. Sphingolipid-polyalkylamine-oligonucleotide compounds
EP4709348A2 (de) 2023-05-12 2026-03-18 Carbocode S.A. Förderung des haarwachstums

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE71104T1 (de) * 1985-08-13 1992-01-15 Solco Basel Ag Neues verfahren zur herstellung von sphingosinderivaten.
JPH0692349B2 (ja) * 1986-03-06 1994-11-16 和光純薬工業株式会社 光学活性不飽和アミノアルコール誘導体の新規な製法
JPS63297351A (ja) * 1987-05-28 1988-12-05 Mect Corp 非天然型セラミド関連化合物及びその製造法
US5110987A (en) 1988-06-17 1992-05-05 Emory University Method of preparing sphingosine derivatives
JP2500799B2 (ja) * 1994-05-06 1996-05-29 和光純薬工業株式会社 光学活性不飽和アミノアルコ―ル誘導体の新規中間体

Also Published As

Publication number Publication date
US6469148B1 (en) 2002-10-22
JP2002544135A (ja) 2002-12-24
EP1187839A1 (de) 2002-03-20
CA2373286A1 (en) 2000-11-16
EP1187839B1 (de) 2003-09-24
CA2373286C (en) 2010-09-28
AU4311400A (en) 2000-11-21
WO2000068238A1 (en) 2000-11-16
AU770635B2 (en) 2004-02-26
IL146120A0 (en) 2002-07-25
DE60005513D1 (de) 2003-10-30
DE60005513T2 (de) 2004-07-15

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