ATE250778T1 - System umd verfahren zum erstellen eines hierarchischen biologischen modells - Google Patents
System umd verfahren zum erstellen eines hierarchischen biologischen modellsInfo
- Publication number
- ATE250778T1 ATE250778T1 AT96911761T AT96911761T ATE250778T1 AT E250778 T1 ATE250778 T1 AT E250778T1 AT 96911761 T AT96911761 T AT 96911761T AT 96911761 T AT96911761 T AT 96911761T AT E250778 T1 ATE250778 T1 AT E250778T1
- Authority
- AT
- Austria
- Prior art keywords
- model
- information
- phenomena
- umd
- creating
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000001413 cellular effect Effects 0.000 abstract 1
- 238000009509 drug development Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/20—Probabilistic models
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/30—Dynamic-time models
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/10—Analysis or design of chemical reactions, syntheses or processes
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/20—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H70/00—ICT specially adapted for the handling or processing of medical references
- G16H70/60—ICT specially adapted for the handling or processing of medical references relating to pathologies
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Theoretical Computer Science (AREA)
- Physiology (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Primary Health Care (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Pathology (AREA)
- Probability & Statistics with Applications (AREA)
- Epidemiology (AREA)
- Computing Systems (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Paper (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Control Of Metal Rolling (AREA)
- Inorganic Insulating Materials (AREA)
- Instruments For Measurement Of Length By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08422175 US5657255C1 (en) | 1995-04-14 | 1995-04-14 | Hierarchic biological modelling system and method |
| PCT/US1996/005155 WO1996032684A1 (en) | 1995-04-14 | 1996-04-12 | Hierarchical biological modelling system and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE250778T1 true ATE250778T1 (de) | 2003-10-15 |
Family
ID=23673709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96911761T ATE250778T1 (de) | 1995-04-14 | 1996-04-12 | System umd verfahren zum erstellen eines hierarchischen biologischen modells |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5657255C1 (de) |
| EP (2) | EP1353288A3 (de) |
| JP (1) | JPH11509655A (de) |
| AT (1) | ATE250778T1 (de) |
| AU (1) | AU5484596A (de) |
| DE (1) | DE69630116T2 (de) |
| DK (1) | DK0827611T3 (de) |
| WO (1) | WO1996032684A1 (de) |
Families Citing this family (97)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6456982B1 (en) * | 1993-07-01 | 2002-09-24 | Dragana N. Pilipovic | Computer system for generating projected data and an application supporting a financial transaction |
| US5930154A (en) * | 1995-01-17 | 1999-07-27 | Intertech Ventures, Ltd. | Computer-based system and methods for information storage, modeling and simulation of complex systems organized in discrete compartments in time and space |
| US6983227B1 (en) | 1995-01-17 | 2006-01-03 | Intertech Ventures, Ltd. | Virtual models of complex systems |
| US5657255C1 (en) * | 1995-04-14 | 2002-06-11 | Interleukin Genetics Inc | Hierarchic biological modelling system and method |
| US6108635A (en) * | 1996-05-22 | 2000-08-22 | Interleukin Genetics, Inc. | Integrated disease information system |
| WO1997044752A1 (en) * | 1996-05-22 | 1997-11-27 | Medical Science Systems, Inc. | Pharmaceutical process system for creating and analyzing information |
| US6246975B1 (en) * | 1996-10-30 | 2001-06-12 | American Board Of Family Practice, Inc. | Computer architecture and process of patient generation, evolution, and simulation for computer based testing system |
| US6056428A (en) * | 1996-11-12 | 2000-05-02 | Invention Machine Corporation | Computer based system for imaging and analyzing an engineering object system and indicating values of specific design changes |
| US6673538B1 (en) | 1997-07-25 | 2004-01-06 | The Trustees Of Boston University | Methods and compositions for designing vaccines |
| AU8513798A (en) | 1997-07-25 | 1999-02-16 | Trustees Of Boston University | Methods and compositions for determining species of bacteria and fungi |
| US6051029A (en) * | 1997-10-31 | 2000-04-18 | Entelos, Inc. | Method of generating a display for a dynamic simulation model utilizing node and link representations |
| US6078739A (en) * | 1997-11-25 | 2000-06-20 | Entelos, Inc. | Method of managing objects and parameter values associated with the objects within a simulation model |
| US6069629A (en) * | 1997-11-25 | 2000-05-30 | Entelos, Inc. | Method of providing access to object parameters within a simulation model |
| US5965352A (en) | 1998-05-08 | 1999-10-12 | Rosetta Inpharmatics, Inc. | Methods for identifying pathways of drug action |
| WO2000003318A2 (en) * | 1998-07-13 | 2000-01-20 | Chandu Corporation | Configurable bio-transport system simulator |
| US20020010550A1 (en) | 1998-09-14 | 2002-01-24 | George M. Grass | Pharmacokinetic-based drug design tool and method |
| EP1145149B1 (de) * | 1998-11-13 | 2005-04-06 | Cellomics, Inc. | Verfahren und system zum effizienten gewinnen und speichern von experimentellen daten |
| US7107253B1 (en) | 1999-04-05 | 2006-09-12 | American Board Of Family Practice, Inc. | Computer architecture and process of patient generation, evolution and simulation for computer based testing system using bayesian networks as a scripting language |
| AU4466700A (en) * | 1999-04-16 | 2000-11-02 | Entelos, Inc. | Method and apparatus for conducting linked simulation operations utilizing a computer-based system model |
| DE60002189T2 (de) * | 1999-04-21 | 2003-10-23 | Physiome Sciences, Inc. | System und verfahren zur modellierung von genetische, biochemische, biophysische und anatomische information |
| WO2001001206A2 (en) * | 1999-06-30 | 2001-01-04 | Strategic Simulation Systems, Inc. | System dynamics model builder and simulator |
| EP1222566A1 (de) * | 1999-09-23 | 2002-07-17 | Chroma Graphics, Inc. | Verfahren und vorrichtung zum beschreiben und simulieren komplexer systeme |
| US7356416B2 (en) | 2000-01-25 | 2008-04-08 | Cellomics, Inc. | Method and system for automated inference creation of physico-chemical interaction knowledge from databases of co-occurrence data |
| WO2001057760A1 (en) * | 2000-02-01 | 2001-08-09 | Ppd Discovery, Inc. | Data processing system for compound development programs |
| DE10007791A1 (de) * | 2000-02-21 | 2001-09-20 | Daidalos Software Gmbh | Verfahren zur Modellierung und Steuerung realer Abläufe in einer Datenverarbeitungsanlage und eine Datenverarbeitungsanlage zur Durchführung des Verfahrens |
| WO2001069239A1 (en) * | 2000-03-10 | 2001-09-20 | New World Science And Technology, Inc. | System and method for simulating cellular biochemical pathways |
| US7216113B1 (en) * | 2000-03-24 | 2007-05-08 | Symyx Technologies, Inc. | Remote Execution of Materials Library Designs |
| IL152740A0 (en) * | 2000-05-31 | 2003-06-24 | Fasttrack Systems Inc | Clinical trials management system and method |
| US20020091666A1 (en) * | 2000-07-07 | 2002-07-11 | Rice John Jeremy | Method and system for modeling biological systems |
| US6813615B1 (en) | 2000-09-06 | 2004-11-02 | Cellomics, Inc. | Method and system for interpreting and validating experimental data with automated reasoning |
| WO2002032035A2 (en) * | 2000-10-10 | 2002-04-18 | University Of Utah Research Foundation | Method and apparatus for monitoring dynamic systems using an integrated graphic display for the n-dimensional representations of critical functions |
| US6871171B1 (en) * | 2000-10-19 | 2005-03-22 | Optimata Ltd. | System and methods for optimized drug delivery and progression of diseased and normal cells |
| US20020087570A1 (en) * | 2000-11-02 | 2002-07-04 | Jacquez Geoffrey M. | Space and time information system and method |
| US7319945B1 (en) * | 2000-11-10 | 2008-01-15 | California Institute Of Technology | Automated methods for simulating a biological network |
| AU2002239619A1 (en) * | 2000-12-08 | 2002-06-18 | Peter J. Ortoleva | Methods for modeling multi-dimensional domains using information theory to resolve gaps in data and in theories |
| US6985846B1 (en) * | 2001-01-31 | 2006-01-10 | Pharsight Corporation | System and method for simulating clinical trial protocols with compiled state machines |
| US6937257B1 (en) * | 2001-01-31 | 2005-08-30 | Pharsight Corporation | Unit tracking and notification in a graphical drug model editor |
| US7353152B2 (en) * | 2001-05-02 | 2008-04-01 | Entelos, Inc. | Method and apparatus for computer modeling diabetes |
| US20020178184A1 (en) * | 2001-05-22 | 2002-11-28 | Allan Kuchinsky | Software system for biological storytelling |
| US7519605B2 (en) | 2001-05-09 | 2009-04-14 | Agilent Technologies, Inc. | Systems, methods and computer readable media for performing a domain-specific metasearch, and visualizing search results therefrom |
| US20050188294A1 (en) * | 2004-02-23 | 2005-08-25 | Kuchinsky Allan J. | Systems, tools and methods for constructing interactive biological diagrams |
| IL158876A0 (en) * | 2001-05-17 | 2004-05-12 | Entelos Inc | Apparatus and method for validating a computer model |
| US20030014232A1 (en) * | 2001-05-22 | 2003-01-16 | Paterson Thomas S. | Methods for predicting biological activities of cellular constituents |
| US6862561B2 (en) * | 2001-05-29 | 2005-03-01 | Entelos, Inc. | Method and apparatus for computer modeling a joint |
| AU2002310210A1 (en) * | 2001-06-01 | 2002-12-16 | Michael N. Liebman | Information processing method for evaluating and using biochemical pathway models using clinical data |
| US20020194201A1 (en) * | 2001-06-05 | 2002-12-19 | Wilbanks John Thompson | Systems, methods and computer program products for integrating biological/chemical databases to create an ontology network |
| US20020194154A1 (en) * | 2001-06-05 | 2002-12-19 | Levy Joshua Lerner | Systems, methods and computer program products for integrating biological/chemical databases using aliases |
| WO2003001891A2 (en) * | 2001-06-28 | 2003-01-09 | Entelos, Inc. | Method and apparatus for computer modeling of an adaptive immune response |
| EP1440410A2 (de) * | 2001-11-02 | 2004-07-28 | Siemens Corporate Research, Inc. | Patientendatenermittlungssystem für lungenkrebsanzeige |
| US7457731B2 (en) * | 2001-12-14 | 2008-11-25 | Siemens Medical Solutions Usa, Inc. | Early detection of disease outbreak using electronic patient data to reduce public health threat from bio-terrorism |
| US20050125158A1 (en) * | 2001-12-19 | 2005-06-09 | Kaiser Foundation Health Plan Inc. | Generating a mathematical model for diabetes |
| US7136787B2 (en) * | 2001-12-19 | 2006-11-14 | Archimedes, Inc. | Generation of continuous mathematical model for common features of a subject group |
| US20030170814A1 (en) * | 2001-12-26 | 2003-09-11 | Sermet Yucel | Systems and methods for providing runtime execution of discovery logic from biological and chemical data |
| US20060293873A1 (en) * | 2002-03-06 | 2006-12-28 | Trustees Of Boston University | Systems and methods for reverse engineering models of biological networks |
| US7680086B2 (en) | 2002-09-09 | 2010-03-16 | Siemens Canada Limited | Wireless local area network with clients having extended freedom of movement |
| US20030125548A1 (en) * | 2002-09-13 | 2003-07-03 | Dorit Arad | Molecules derived from mechanism based drug design |
| US8489336B2 (en) | 2002-09-16 | 2013-07-16 | Optimata Ltd. | Techniques for purposing a new compound and for re-purposing a drug |
| AU2003269395A1 (en) * | 2002-09-16 | 2004-04-30 | Optimata, Ltd. | An interactive technique for optimizing drug development from the pre-clinical phases through phase-iv |
| US20040115647A1 (en) * | 2002-12-12 | 2004-06-17 | Paterson Thomas S. | Apparatus and method for identifying biomarkers using a computer model |
| US8504380B2 (en) * | 2003-06-05 | 2013-08-06 | Medidata Solutions, Inc. | Assistance for clinical trial protocols |
| US7853406B2 (en) * | 2003-06-13 | 2010-12-14 | Entelos, Inc. | Predictive toxicology for biological systems |
| US20050130192A1 (en) * | 2003-09-11 | 2005-06-16 | Paterson Thomas S. | Apparatus and method for identifying therapeutic targets using a computer model |
| US20050059083A1 (en) * | 2003-09-15 | 2005-03-17 | Becton Dickinson And Company | High throughput method to identify ligands for cell attachment |
| US20050060100A1 (en) * | 2003-09-15 | 2005-03-17 | Becton Dickinson And Company | Computer software and algorithms for systems biologically linked to cellular phenotype |
| JP2007507814A (ja) * | 2003-10-07 | 2007-03-29 | エンテロス・インコーポレーテッド | 患者に固有の結果のシミュレーション |
| US20050079511A1 (en) * | 2003-10-14 | 2005-04-14 | Pharsight Corporation | Drug model explorer |
| EP1696790B1 (de) * | 2003-11-19 | 2011-11-02 | Entelos, Inc. | Verfahren zur Beurteilung der Nutzung von metabolischem Substrat und der Wirksamkeit einer Therapie |
| US20050154534A1 (en) * | 2004-01-13 | 2005-07-14 | Becton, Dickinson And Company | Automated media optimization technology |
| JPWO2005083615A1 (ja) * | 2004-02-26 | 2007-11-29 | 国立大学法人京都大学 | 生体シミュレーション装置およびプログラム |
| JP5102439B2 (ja) * | 2004-05-11 | 2012-12-19 | シスメックス株式会社 | シミュレーションシステム及びコンピュータプログラム |
| US20060025929A1 (en) * | 2004-07-30 | 2006-02-02 | Chris Eglington | Method of determining a genetic relationship to at least one individual in a group of famous individuals using a combination of genetic markers |
| US7493333B2 (en) | 2004-09-03 | 2009-02-17 | Biowisdom Limited | System and method for parsing and/or exporting data from one or more multi-relational ontologies |
| US7496593B2 (en) | 2004-09-03 | 2009-02-24 | Biowisdom Limited | Creating a multi-relational ontology having a predetermined structure |
| US7505989B2 (en) | 2004-09-03 | 2009-03-17 | Biowisdom Limited | System and method for creating customized ontologies |
| JP2007334377A (ja) * | 2004-09-27 | 2007-12-27 | Kyoto Univ | 生体シミュレーション装置およびプログラム |
| CA2596816A1 (en) * | 2005-02-04 | 2006-08-10 | Entelos, Inc. | Method for defining virtual patient populations |
| AU2006222889A1 (en) * | 2005-03-15 | 2006-09-21 | Entelos, Inc. | Apparatus and method for computer modeling type 1 diabetes |
| US20060265253A1 (en) * | 2005-05-18 | 2006-11-23 | Rao R B | Patient data mining improvements |
| US7581998B2 (en) * | 2005-09-08 | 2009-09-01 | Ngk Spark Plug Co., Ltd. | Method for regulating aground electrode position in spark plug |
| US7734423B2 (en) * | 2005-09-23 | 2010-06-08 | Crowley Davis Research, Inc. | Method, system, and apparatus for virtual modeling of biological tissue with adaptive emergent functionality |
| CA2628108C (en) * | 2005-11-10 | 2020-01-07 | Certara Usa, Inc. | Method and apparatus for computer modeling the human brain for predicting drug effects |
| US20100049492A1 (en) * | 2006-09-12 | 2010-02-25 | Entelos, Inc. | Method and apparatus for modeling skin sensitization |
| US20090070087A1 (en) * | 2007-09-07 | 2009-03-12 | Newman Richard D | Virtual tissue with emergent behavior and modeling method for producing the tissue |
| JP2009104558A (ja) * | 2007-10-25 | 2009-05-14 | Osaka Univ | シミュレーション装置、生体モデルのデータ構造、モデル作成装置、検索装置、生体モデル開発システム、モデル作成プログラムおよび記録媒体 |
| EP2223248A4 (de) * | 2007-11-13 | 2012-01-18 | Entelos Inc | Simulation von patientenspezifischen ergebnissen |
| US20100299289A1 (en) * | 2009-05-20 | 2010-11-25 | The George Washington University | System and method for obtaining information about biological networks using a logic based approach |
| US10943676B2 (en) | 2010-06-08 | 2021-03-09 | Cerner Innovation, Inc. | Healthcare information technology system for predicting or preventing readmissions |
| US9092566B2 (en) | 2012-04-20 | 2015-07-28 | International Drug Development Institute | Methods for central monitoring of research trials |
| US20140081659A1 (en) | 2012-09-17 | 2014-03-20 | Depuy Orthopaedics, Inc. | Systems and methods for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking |
| US9779063B1 (en) | 2013-03-15 | 2017-10-03 | Not Invented Here LLC | Document processor program having document-type dependent interface |
| EP3402900A1 (de) | 2016-01-12 | 2018-11-21 | Interleukin Genetics, Inc. | Verfahren zur vorhersage der reaktion auf eine therapie |
| US20190164631A1 (en) | 2016-05-19 | 2019-05-30 | Simplicitybio Sa | Biomarkers signature discovery and selection |
| US10329620B2 (en) | 2017-01-12 | 2019-06-25 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| US11288595B2 (en) * | 2017-02-14 | 2022-03-29 | Groq, Inc. | Minimizing memory and processor consumption in creating machine learning models |
| WO2020245402A1 (en) | 2019-06-06 | 2020-12-10 | Cardioforecast Ltd | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3800288A (en) * | 1972-02-24 | 1974-03-26 | Foxboro Co | Computer-directed process control system with crt display |
| US4881175A (en) * | 1986-09-02 | 1989-11-14 | Genex Corporation | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US5005143A (en) * | 1987-06-19 | 1991-04-02 | University Of Pennsylvania | Interactive statistical system and method for predicting expert decisions |
| US5025388A (en) * | 1988-08-26 | 1991-06-18 | Cramer Richard D Iii | Comparative molecular field analysis (CoMFA) |
| GB8823747D0 (en) * | 1988-10-10 | 1988-11-16 | Vickers Shipbuilding & Eng | System design tool |
| US5081584A (en) * | 1989-03-13 | 1992-01-14 | United States Of America | Computer-assisted design of anti-peptides based on the amino acid sequence of a target peptide |
| US5331573A (en) * | 1990-12-14 | 1994-07-19 | Balaji Vitukudi N | Method of design of compounds that mimic conformational features of selected peptides |
| EP0496902A1 (de) * | 1991-01-26 | 1992-08-05 | International Business Machines Corporation | Wissensbasiertes System und Verfahren zur Wiederauffindung von Moleküldaten |
| US5424963A (en) * | 1992-11-25 | 1995-06-13 | Photon Research Associates, Inc. | Molecular dynamics simulation method and apparatus |
| US6081766A (en) * | 1993-05-21 | 2000-06-27 | Axys Pharmaceuticals, Inc. | Machine-learning approach to modeling biological activity for molecular design and to modeling other characteristics |
| US5434796A (en) * | 1993-06-30 | 1995-07-18 | Daylight Chemical Information Systems, Inc. | Method and apparatus for designing molecules with desired properties by evolving successive populations |
| US5495423A (en) * | 1993-10-25 | 1996-02-27 | Trustees Of Boston University | General strategy for vaccine and drug design |
| US5463564A (en) * | 1994-09-16 | 1995-10-31 | 3-Dimensional Pharmaceuticals, Inc. | System and method of automatically generating chemical compounds with desired properties |
| US5657255C1 (en) * | 1995-04-14 | 2002-06-11 | Interleukin Genetics Inc | Hierarchic biological modelling system and method |
-
1995
- 1995-04-14 US US08422175 patent/US5657255C1/en not_active Expired - Lifetime
-
1996
- 1996-04-12 AT AT96911761T patent/ATE250778T1/de not_active IP Right Cessation
- 1996-04-12 EP EP03015906A patent/EP1353288A3/de not_active Withdrawn
- 1996-04-12 EP EP96911761A patent/EP0827611B1/de not_active Expired - Lifetime
- 1996-04-12 JP JP8531253A patent/JPH11509655A/ja active Pending
- 1996-04-12 DK DK96911761T patent/DK0827611T3/da active
- 1996-04-12 DE DE69630116T patent/DE69630116T2/de not_active Expired - Lifetime
- 1996-04-12 WO PCT/US1996/005155 patent/WO1996032684A1/en not_active Ceased
- 1996-04-12 AU AU54845/96A patent/AU5484596A/en not_active Abandoned
-
1997
- 1997-06-25 US US08882597 patent/US5808918C1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1353288A2 (de) | 2003-10-15 |
| EP1353288A3 (de) | 2005-01-12 |
| US5657255A (en) | 1997-08-12 |
| EP0827611A4 (de) | 1999-09-22 |
| EP0827611A1 (de) | 1998-03-11 |
| EP0827611B1 (de) | 2003-09-24 |
| DK0827611T3 (da) | 2004-02-09 |
| US5808918A (en) | 1998-09-15 |
| JPH11509655A (ja) | 1999-08-24 |
| US5657255C1 (en) | 2002-06-11 |
| DE69630116D1 (de) | 2003-10-30 |
| WO1996032684A1 (en) | 1996-10-17 |
| US5808918C1 (en) | 2002-06-25 |
| DE69630116T2 (de) | 2004-06-17 |
| AU5484596A (en) | 1996-10-30 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |