ATE251142T1 - Eine kristallmodifikation von celecoxib - Google Patents

Eine kristallmodifikation von celecoxib

Info

Publication number: ATE251142T1
Authority: AT; Austria
Prior art keywords: celecoxib; crystal modification; ylübenzenesulfo; namide; pyrazol
Prior art date: 2000-06-26

Application number

AT01106333T

Other languages

English (en)

Inventor

Halit Guenduez

Mehmet Bahar

Mehmet Goektepe

Original Assignee

Fako Ilaclari A S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-26

Filing date

2001-03-15

Publication date

2003-10-15

2001-03-15 Application filed by Fako Ilaclari A S filed Critical Fako Ilaclari A S

2003-10-15 Application granted granted Critical

2003-10-15 Publication of ATE251142T1 publication Critical patent/ATE251142T1/de

Links

RZEKVGVHFLEQIL-UHFFFAOYSA-N celecoxib Chemical compound C1=CC(C)=CC=C1C1=CC(C(F)(F)F)=NN1C1=CC=C(S(N)(=O)=O)C=C1 RZEKVGVHFLEQIL-UHFFFAOYSA-N 0.000 title 1
229960000590 celecoxib Drugs 0.000 title 1
239000013078 crystal Substances 0.000 title 1
230000004048 modification Effects 0.000 title 1
238000012986 modification Methods 0.000 title 1
LQVXSNNAFNGRAH-QHCPKHFHSA-N BMS-754807 Chemical compound C([C@@]1(C)C(=O)NC=2C=NC(F)=CC=2)CCN1C(=NN1C=CC=C11)N=C1NC(=NN1)C=C1C1CC1 LQVXSNNAFNGRAH-QHCPKHFHSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT01106333T 2000-06-26 2001-03-15 Eine kristallmodifikation von celecoxib ATE251142T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
TR2000/01872A TR200001872A3 (tr)	2000-06-26	2000-06-26	4-[5-(4-Metilfenil-3-(triflorometil)-1H-pirazol-1-il] benzensulfonamit' in yeni kristal biçimi "Biçim I" ve bu ürünün üretilmesine iliskin yöntem.

Publications (1)

Publication Number	Publication Date
ATE251142T1 true ATE251142T1 (de)	2003-10-15

Family

ID=21622570

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01106333T ATE251142T1 (de)	2000-06-26	2001-03-15	Eine kristallmodifikation von celecoxib

Country Status (13)

Country	Link
US (1)	US6391906B2 (de)
EP (1)	EP1167355B1 (de)
AT (1)	ATE251142T1 (de)
AU (1)	AU2001276808A1 (de)
CA (1)	CA2350956C (de)
DE (1)	DE60100873T2 (de)
EA (1)	EA004470B1 (de)
ES (1)	ES2206360T3 (de)
HK (1)	HK1045155B (de)
IL (1)	IL153615A0 (de)
PT (1)	PT1167355E (de)
TR (1)	TR200001872A3 (de)
WO (1)	WO2002000627A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA74539C2 (en) *	1999-12-08	2006-01-16	Pharmacia Corp	Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants)
DE10135027A1 (de) *	2001-07-18	2003-02-06	Solvay Pharm Gmbh	Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen
US6579988B2 (en)	2001-09-18	2003-06-17	Onconova Therapeutics, Inc.	Processes for the preparation of 1,5-diarylpyrazoles
JP2005508320A (ja)	2001-09-18	2005-03-31	オンコノバ・セラピューティックス・インコーポレーテッド	１，５−ジアリール−３−置換ピラゾールの調製方法
WO2004061433A1 (en) *	2002-12-30	2004-07-22	Transform Pharmaceuticals, Inc.	Pharmaceutical compositions with improved dissolution
US7927613B2 (en)	2002-02-15	2011-04-19	University Of South Florida	Pharmaceutical co-crystal compositions
US7790905B2 (en)	2002-02-15	2010-09-07	Mcneil-Ppc, Inc.	Pharmaceutical propylene glycol solvate compositions
AU2003213719A1 (en)	2002-03-01	2003-09-16	Regents Of The University Of Michigan	Multiple-component solid phases containing at least one active pharmaceutical ingredient
WO2003090730A1 (en) *	2002-04-25	2003-11-06	Generics [Uk] Limited	Novel crystalline forms of celecoxib and other compounds
WO2003091221A1 (en) *	2002-04-25	2003-11-06	Generics [Uk] Limited	Celecoxib forms
MXPA04011654A (es) *	2002-05-24	2005-03-07	Pharmacia Corp	Sintesis de diarilpirazoles.
IL165383A0 (en)	2002-06-21	2006-01-15	Transform Pharmaceuticals Inc	Pharmaceutical compositions with improved dissolution
US8183290B2 (en)	2002-12-30	2012-05-22	Mcneil-Ppc, Inc.	Pharmaceutically acceptable propylene glycol solvate of naproxen
WO2005095349A1 (en) *	2004-04-01	2005-10-13	Pharmacia & Upjohn Company Llc	Crystalline pyrazole derivative
WO2006024930A1 (en) *	2004-09-01	2006-03-09	Pharmacia & Upjohn Company Llc	Novel co-crystals between polyethylene glycols and 5-phenylpyrazolyl-1-benzenesulfonamides
EP1846566B1 (de) *	2004-10-28	2013-04-03	DSM IP Assets B.V.	Stabile nadelförmige natamycinkristalle
EP1846377A2 (de) *	2005-01-31	2007-10-24	Pharmacia & Upjohn Company LLC	Kristallines form-iv-celecoxib
BRPI0810590A2 (pt) *	2007-05-25	2014-10-21	Exxonmobil Upstream Res Co	Método in situ de produzir fluidos de hidrocarboneto de uma formação rochosa rica em matéria orgânica
WO2011055233A2 (en)	2009-11-03	2011-05-12	Actavis Group Ptc Ehf	Improved process for preparing celecoxib polymorph
US20110213159A1 (en)	2010-03-01	2011-09-01	Vamsee Krishna Muppidi	Process for preparation of celecoxib crystalline form
CN103524416B (zh) *	2013-10-29	2016-08-17	湖北华世通生物医药科技有限公司	一种塞来昔布新晶型a及其制备方法
CN103539739B (zh) *	2013-10-30	2016-02-10	中美华世通生物医药科技（武汉）有限公司	一种塞来昔布新晶型b及其制备方法
CN103508958A (zh) *	2013-10-30	2014-01-15	中美华世通生物医药科技（武汉）有限公司	一种塞来昔布新晶型c及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5604260A (en)	1992-12-11	1997-02-18	Merck Frosst Canada Inc.	5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
DE69422306T4 (de) *	1993-11-30	2000-09-07	G.D. Searle & Co., Chicago	Substituierte pyrazolyl-benzolsulfonamide zur behandlung von entzündungen
EP0828717B1 (de) *	1995-05-25	2002-09-04	G.D. SEARLE & CO.	Verfahren zur herstellung von 3-haloalkyl-1h-pyrazole
JP2002534509A (ja) *	1999-01-14	2002-10-15	メルクフロストカナダアンドカンパニー	４−［（５−置換または未置換フェニル）−３−置換−１ｈ−ピラゾール−１−イル］ベンゼンスルホンアミド類の合成
UA74539C2 (en) *	1999-12-08	2006-01-16	Pharmacia Corp	Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants)

2000
- 2000-06-26 TR TR2000/01872A patent/TR200001872A3/tr unknown
2001
- 2001-03-15 ES ES01106333T patent/ES2206360T3/es not_active Expired - Lifetime
- 2001-03-15 AT AT01106333T patent/ATE251142T1/de not_active IP Right Cessation
- 2001-03-15 DE DE60100873T patent/DE60100873T2/de not_active Expired - Lifetime
- 2001-03-15 PT PT01106333T patent/PT1167355E/pt unknown
- 2001-03-15 EP EP01106333A patent/EP1167355B1/de not_active Expired - Lifetime
- 2001-06-18 CA CA002350956A patent/CA2350956C/en not_active Expired - Fee Related
- 2001-06-22 US US09/887,354 patent/US6391906B2/en not_active Expired - Fee Related
- 2001-06-26 EA EA200300067A patent/EA004470B1/ru not_active IP Right Cessation
- 2001-06-26 IL IL15361501A patent/IL153615A0/xx unknown
- 2001-06-26 WO PCT/TR2001/000025 patent/WO2002000627A1/en not_active Ceased
- 2001-06-26 AU AU2001276808A patent/AU2001276808A1/en not_active Abandoned
2002
- 2002-06-28 HK HK02104883.0A patent/HK1045155B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE60100873T2 (de)	2004-07-22
EP1167355A1 (de)	2002-01-02
WO2002000627A1 (en)	2002-01-03
ES2206360T3 (es)	2004-05-16
HK1045155B (en)	2004-05-28
CA2350956A1 (en)	2001-12-26
PT1167355E (pt)	2004-02-27
DE60100873D1 (de)	2003-11-06
CA2350956C (en)	2005-08-23
EA200300067A1 (ru)	2003-06-26
EA004470B1 (ru)	2004-04-29
US20020016351A1 (en)	2002-02-07
IL153615A0 (en)	2003-07-06
US6391906B2 (en)	2002-05-21
TR200001872A2 (tr)	2002-01-21
TR200001872A3 (tr)	2002-01-21
AU2001276808A1 (en)	2002-01-08
HK1045155A1 (en)	2002-11-15
EP1167355B1 (de)	2003-10-01

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Legal Events

Date	Code	Title	Description
2004-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties