ATE252543T1 - Verfahren zur herstellung chiraler (s)-2,3- disubstituierter 1-propylamin-derivate - Google Patents
Verfahren zur herstellung chiraler (s)-2,3- disubstituierter 1-propylamin-derivateInfo
- Publication number
- ATE252543T1 ATE252543T1 AT99914788T AT99914788T ATE252543T1 AT E252543 T1 ATE252543 T1 AT E252543T1 AT 99914788 T AT99914788 T AT 99914788T AT 99914788 T AT99914788 T AT 99914788T AT E252543 T1 ATE252543 T1 AT E252543T1
- Authority
- AT
- Austria
- Prior art keywords
- disubstituted
- derivatives
- propylamin
- producing chiral
- chiral
- Prior art date
Links
- -1 (S)-2,3-DISUBSTITUTED 1-PROPYLAMIN Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000006969 Curtius rearrangement reaction Methods 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/54—Preparation of compounds containing amino groups bound to a carbon skeleton by rearrangement reactions
- C07C209/56—Preparation of compounds containing amino groups bound to a carbon skeleton by rearrangement reactions from carboxylic acids involving a Hofmann, Curtius, Schmidt, or Lossen-type rearrangement
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019980013172A KR100489649B1 (ko) | 1998-04-14 | 1998-04-14 | (s)-3-치환-2-히드록시프로필아민의제조방법 |
| KR1019980013173A KR100469946B1 (ko) | 1998-04-14 | 1998-04-14 | 키랄(s)-2,3-치환-1-프로필아민유도체의제조방법 |
| KR1019980013174A KR100469947B1 (ko) | 1998-04-14 | 1998-04-14 | 키랄(s)-3-아미노-1,2-프로판디올의제조방법 |
| PCT/KR1999/000178 WO1999052855A1 (en) | 1998-04-14 | 1999-04-14 | A process for preparing chiral (s)-2,3-disubstituted-1-propylamine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE252543T1 true ATE252543T1 (de) | 2003-11-15 |
Family
ID=27349711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99914788T ATE252543T1 (de) | 1998-04-14 | 1999-04-14 | Verfahren zur herstellung chiraler (s)-2,3- disubstituierter 1-propylamin-derivate |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6417403B1 (de) |
| EP (1) | EP1071654B1 (de) |
| JP (1) | JP2002511445A (de) |
| CN (1) | CN1301248A (de) |
| AT (1) | ATE252543T1 (de) |
| AU (1) | AU3345599A (de) |
| CA (1) | CA2328124A1 (de) |
| DE (1) | DE69912264T2 (de) |
| WO (1) | WO1999052855A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1331218B1 (de) * | 1998-06-01 | 2006-12-27 | Michigan State University | Verfahren zur Herstellung von geschützten 3-Amino-1,2-Dihydroxypropanacetal und Derivate davon |
| US6040464A (en) * | 1998-06-01 | 2000-03-21 | Board Of Trustees Operating Michigan State University | Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof |
| DE69933526D1 (de) | 1998-12-07 | 2006-11-23 | Takasago Perfumery Co Ltd | Verfahren zur Herstellung von optisch aktiven Oxazolidinonderivate |
| JPWO2004002973A1 (ja) * | 2002-06-28 | 2005-10-27 | 株式会社カネカ | 光学活性１−置換アミノ−２，３−エポキシプロパンの製造方法並びにその合成中間体およびそれらの製造方法 |
| CA2603943A1 (en) * | 2005-04-06 | 2006-10-12 | Pharmacia & Upjohn Company Llc | An oxindole oxazolidinone as antibacterial agent |
| AU2006231919A1 (en) * | 2005-04-06 | 2006-10-12 | Pharmacia & Upjohn Company Llc | 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents |
| US9024028B2 (en) | 2011-01-26 | 2015-05-05 | Ariad Pharmaceuticals, Inc. | Methods and compositions for the synthesis of multimerizing agents |
| GEP20156397B (en) * | 2011-05-06 | 2015-11-10 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Process for the preparation of a rivaroxaban and intermediates formed in said process |
| US10022531B2 (en) | 2016-01-21 | 2018-07-17 | Teva Medical Ltd. | Luer lock adaptor |
| WO2019070981A1 (en) * | 2017-10-05 | 2019-04-11 | Novomer, Inc. | ISOCYANATES, DERIVATIVES, AND THEIR PRODUCTION PROCESSES |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3855283A (en) * | 1969-07-29 | 1974-12-17 | American Cyanamid Co | Levo 1-amino-3-chloro-2-propanol and acid addition salts thereof |
| US4582855A (en) * | 1981-11-12 | 1986-04-15 | American Hospital Supply Corporation | Aromatic and esters of hydroxypropylamines |
| US4900847A (en) | 1985-04-04 | 1990-02-13 | Massachusetts Institute Of Technology | Catalytic asymmetric epoxidation |
| SE468211B (sv) * | 1990-01-22 | 1992-11-23 | Nobel Chemicals Ab | Flerstegsfoerfarande foer framstaellning av homokirala aminer |
| CA2049536C (en) | 1991-05-13 | 1999-07-06 | Rawle I. Hollingsworth | Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof |
| DE4315623A1 (de) * | 1993-05-11 | 1994-11-17 | Hoechst Ag | Verfahren zur Herstellung von Aminen |
-
1999
- 1999-04-14 JP JP2000543418A patent/JP2002511445A/ja active Pending
- 1999-04-14 AT AT99914788T patent/ATE252543T1/de not_active IP Right Cessation
- 1999-04-14 AU AU33455/99A patent/AU3345599A/en not_active Abandoned
- 1999-04-14 EP EP99914788A patent/EP1071654B1/de not_active Expired - Lifetime
- 1999-04-14 US US09/673,123 patent/US6417403B1/en not_active Expired - Fee Related
- 1999-04-14 WO PCT/KR1999/000178 patent/WO1999052855A1/en not_active Ceased
- 1999-04-14 DE DE69912264T patent/DE69912264T2/de not_active Expired - Fee Related
- 1999-04-14 CA CA002328124A patent/CA2328124A1/en not_active Abandoned
- 1999-04-14 CN CN99806311A patent/CN1301248A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1071654A1 (de) | 2001-01-31 |
| EP1071654B1 (de) | 2003-10-22 |
| AU3345599A (en) | 1999-11-01 |
| CA2328124A1 (en) | 1999-10-21 |
| DE69912264T2 (de) | 2004-07-22 |
| DE69912264D1 (de) | 2003-11-27 |
| CN1301248A (zh) | 2001-06-27 |
| WO1999052855A1 (en) | 1999-10-21 |
| US6417403B1 (en) | 2002-07-09 |
| JP2002511445A (ja) | 2002-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |