ATE252594T1 - Verfahren zur herstellung von ribavirin - Google Patents

Verfahren zur herstellung von ribavirin

Info

Publication number: ATE252594T1
Authority: AT; Austria
Prior art keywords: chem; formula; ribavirin; reaction; group
Prior art date: 2001-07-30

Application number

AT01830510T

Other languages

English (en)

Inventor

Aldo Banfi

Oro Bruno Dall

Marco Frigerio

Alfredo Mancini

Original Assignee

Clariant Lsm Italia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-30

Filing date

2001-07-30

Publication date

2003-11-15

2001-07-30 Application filed by Clariant Lsm Italia Spa filed Critical Clariant Lsm Italia Spa

2003-11-15 Application granted granted Critical

2003-11-15 Publication of ATE252594T1 publication Critical patent/ATE252594T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT01830510T 2001-07-30 2001-07-30 Verfahren zur herstellung von ribavirin ATE252594T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01830510A EP1281715B1 (de)	2001-07-30	2001-07-30	Verfahren zur Herstellung von Ribavirin

Publications (1)

Publication Number	Publication Date
ATE252594T1 true ATE252594T1 (de)	2003-11-15

Family

ID=8184638

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT01830510T ATE252594T1 (de)	2001-07-30	2001-07-30	Verfahren zur herstellung von ribavirin
AT02764788T ATE286062T1 (de)	2001-07-30	2002-07-25	Verfahren zur herstellung von l-ribavirin

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT02764788T ATE286062T1 (de)	2001-07-30	2002-07-25	Verfahren zur herstellung von l-ribavirin

Country Status (13)

Country	Link
US (2)	US7285660B2 (de)
EP (2)	EP1281715B1 (de)
JP (2)	JP2004538317A (de)
KR (2)	KR20040031784A (de)
CN (2)	CN1255420C (de)
AT (2)	ATE252594T1 (de)
AU (1)	AU2002328974A1 (de)
BR (2)	BR0210278A (de)
DE (2)	DE60101056T2 (de)
ES (2)	ES2208540T3 (de)
HU (2)	HUP0401615A2 (de)
MX (2)	MXPA04000382A (de)
WO (2)	WO2003011883A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005539032A (ja)	2002-08-12	2005-12-22	エフ．ホフマン−ラ　ロシュ　アーゲー	リボフラノースの製造方法
EP1904071A2 (de) *	2005-07-08	2008-04-02	Aurobindo Pharma Limited	Zusammensetzungen einer antiviralen verbindung
JP2008222630A (ja) *	2007-03-12	2008-09-25	Permachem Asia Ltd	１−β−Ｄ−リボフラノシルー１，２，４−トリアゾール−３−カルボキサミドのＲ−ＩＩ型結晶の製造法
CN101891786B (zh) *	2010-08-04	2012-09-05	王明	一种利巴韦林化合物及其制法
WO2012075140A1 (en)	2010-11-30	2012-06-07	Pharmasset, Inc.	Compounds
CN102127134B (zh) *	2010-12-02	2012-11-14	海南美兰史克制药有限公司	一种利巴韦林化合物及其方法
CN102532226B (zh) *	2010-12-15	2014-05-07	上海迪赛诺医药发展有限公司	利巴韦林晶型及其制备方法
CN109134565A (zh) *	2017-08-15	2019-01-04	李双喜	一种1/10水利巴韦林化合物及其药物组合物
CN109134566A (zh) *	2017-08-18	2019-01-04	樊艳芳	一种1/20水利巴韦林化合物
CN108484691A (zh) *	2018-06-28	2018-09-04	牡丹江师范学院	一种利巴韦林缩合物的化学合成方法
CN111647033A (zh) *	2020-06-08	2020-09-11	济南明鑫制药股份有限公司	一锅法制备利巴韦林的方法
CN115322236A (zh) *	2022-09-06	2022-11-11	启东东岳药业有限公司	合成利巴韦林的新方法
WO2025240242A1 (en)	2024-05-13	2025-11-20	Gilead Sciences, Inc.	Combination therapies with ribavirin
WO2025240246A1 (en)	2024-05-13	2025-11-20	Gilead Sciences, Inc.	Combination therapies with ribavirin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3798209A (en) *	1971-06-01	1974-03-19	Icn Pharmaceuticals	1,2,4-triazole nucleosides
JPS55160793A (en) *	1979-05-29	1980-12-13	Microbial Chem Res Found	Preparation of virazole
JPS5931797A (ja) *	1982-08-18	1984-02-20	Sumitomo Chem Co Ltd	新規１−置換イミダゾ−ルヌクレオシドおよびその製造法
JPS60252493A (ja) *	1984-05-25	1985-12-13	Takeda Chem Ind Ltd	シチジン誘導体の製造法
YU59288A (en) *	1987-03-25	1989-12-31	Wellcome Found	New process for obtaining timine derivatives
CN1049435C (zh) *	1994-11-09	2000-02-16	中国科学院上海药物研究所	含苯基和杂环基的青蒿素衍生物及其制备方法
AU738170B2 (en) *	1996-10-16	2001-09-13	Icn Pharmaceuticals, Inc.	Monocyclic L-nucleosides, analogs and uses thereof
EP1254911A1 (de) *	1996-10-16	2002-11-06	ICN Pharmaceuticals, Inc.	Monozyklische L-Nukleoside, analoga und ihre Anwendungen

2001
- 2001-07-30 DE DE60101056T patent/DE60101056T2/de not_active Expired - Lifetime
- 2001-07-30 EP EP01830510A patent/EP1281715B1/de not_active Expired - Lifetime
- 2001-07-30 ES ES01830510T patent/ES2208540T3/es not_active Expired - Lifetime
- 2001-07-30 AT AT01830510T patent/ATE252594T1/de not_active IP Right Cessation
2002
- 2002-07-25 AU AU2002328974A patent/AU2002328974A1/en not_active Abandoned
- 2002-07-25 US US10/485,436 patent/US7285660B2/en not_active Expired - Fee Related
- 2002-07-25 DE DE60202483T patent/DE60202483T2/de not_active Expired - Fee Related
- 2002-07-25 MX MXPA04000382A patent/MXPA04000382A/es active IP Right Grant
- 2002-07-25 WO PCT/EP2002/008330 patent/WO2003011883A2/en not_active Ceased
- 2002-07-25 KR KR10-2004-7001404A patent/KR20040031784A/ko not_active Ceased
- 2002-07-25 CN CNB028149246A patent/CN1255420C/zh not_active Expired - Fee Related
- 2002-07-25 HU HU0401615A patent/HUP0401615A2/hu unknown
- 2002-07-25 JP JP2003517074A patent/JP2004538317A/ja active Pending
- 2002-07-25 AT AT02764788T patent/ATE286062T1/de not_active IP Right Cessation
- 2002-07-25 BR BR0210278-1A patent/BR0210278A/pt not_active IP Right Cessation
- 2002-07-25 EP EP02764788A patent/EP1414836B1/de not_active Expired - Lifetime
- 2002-07-25 ES ES02764788T patent/ES2233857T3/es not_active Expired - Lifetime
- 2002-07-29 WO PCT/IB2002/002950 patent/WO2003011884A1/en not_active Ceased
- 2002-07-29 MX MXPA03010251A patent/MXPA03010251A/es active IP Right Grant
- 2002-07-29 HU HU0401899A patent/HUP0401899A2/hu unknown
- 2002-07-29 CN CNB028149254A patent/CN1255421C/zh not_active Expired - Fee Related
- 2002-07-29 BR BR0209815-6A patent/BR0209815A/pt not_active IP Right Cessation
- 2002-07-29 JP JP2003517075A patent/JP2004538318A/ja active Pending
- 2002-07-29 KR KR1020047001334A patent/KR100953031B1/ko not_active Expired - Fee Related
- 2002-07-29 US US10/485,335 patent/US7285659B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE60101056D1 (de)	2003-11-27
HUP0401615A2 (hu)	2004-11-29
JP2004538318A (ja)	2004-12-24
ES2208540T3 (es)	2004-06-16
WO2003011884A1 (en)	2003-02-13
JP2004538317A (ja)	2004-12-24
EP1414836B1 (de)	2004-12-29
CN1255420C (zh)	2006-05-10
DE60202483T2 (de)	2005-12-29
WO2003011883A3 (en)	2003-04-17
HUP0401899A2 (hu)	2004-12-28
MXPA04000382A (es)	2004-07-23
KR20040021670A (ko)	2004-03-10
KR20040031784A (ko)	2004-04-13
DE60202483D1 (de)	2005-02-03
EP1281715B1 (de)	2003-10-22
ES2233857T3 (es)	2005-06-16
CN1535277A (zh)	2004-10-06
DE60101056T2 (de)	2004-05-19
WO2003011883A2 (en)	2003-02-13
MXPA03010251A (es)	2004-03-16
BR0210278A (pt)	2004-07-20
EP1281715A1 (de)	2003-02-05
EP1414836A2 (de)	2004-05-06
CN1535278A (zh)	2004-10-06
BR0209815A (pt)	2004-06-01
ATE286062T1 (de)	2005-01-15
KR100953031B1 (ko)	2010-04-14
AU2002328974A1 (en)	2003-02-17
US7285660B2 (en)	2007-10-23
US7285659B2 (en)	2007-10-23
US20040192904A1 (en)	2004-09-30
US20040176587A1 (en)	2004-09-09
CN1255421C (zh)	2006-05-10

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Legal Events

Date	Code	Title	Description
2004-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties