ATE252638T1 - Das humane jtvi-gen überlappt mit dem pms2-gen - Google Patents
Das humane jtvi-gen überlappt mit dem pms2-genInfo
- Publication number
- ATE252638T1 ATE252638T1 AT96930577T AT96930577T ATE252638T1 AT E252638 T1 ATE252638 T1 AT E252638T1 AT 96930577 T AT96930577 T AT 96930577T AT 96930577 T AT96930577 T AT 96930577T AT E252638 T1 ATE252638 T1 AT E252638T1
- Authority
- AT
- Austria
- Prior art keywords
- hpms2
- gene
- found
- initiating methionine
- jtvi
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 108010074346 Mismatch Repair Endonuclease PMS2 Proteins 0.000 title 1
- 208000008051 Hereditary Nonpolyposis Colorectal Neoplasms Diseases 0.000 abstract 2
- 208000017095 Hereditary nonpolyposis colon cancer Diseases 0.000 abstract 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 2
- 239000002299 complementary DNA Substances 0.000 abstract 2
- 230000000977 initiatory effect Effects 0.000 abstract 2
- 229930182817 methionine Natural products 0.000 abstract 2
- 108020004705 Codon Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 108020005038 Terminator Codon Proteins 0.000 abstract 1
- 230000033607 mismatch repair Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000003757 reverse transcription PCR Methods 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Glass Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/518,862 US5843757A (en) | 1995-08-24 | 1995-08-24 | Human JTV1 gene overlaps PMS2 gene |
| PCT/US1996/013598 WO1997008312A1 (en) | 1995-08-24 | 1996-08-26 | Human jtv1 gene overlaps pms2 gene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE252638T1 true ATE252638T1 (de) | 2003-11-15 |
Family
ID=24065808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96930577T ATE252638T1 (de) | 1995-08-24 | 1996-08-26 | Das humane jtvi-gen überlappt mit dem pms2-gen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5843757A (de) |
| EP (1) | EP0852620B1 (de) |
| JP (1) | JPH11511323A (de) |
| AT (1) | ATE252638T1 (de) |
| CA (1) | CA2229789A1 (de) |
| DE (1) | DE69630458D1 (de) |
| WO (1) | WO1997008312A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6146894A (en) | 1998-04-14 | 2000-11-14 | The Johns Hopkins University | Method for generating hypermutable organisms |
| DE60135312D1 (de) | 2000-02-11 | 2008-09-25 | Morphotek Inc | Methode zur herstellung hypermutierender bakterien |
| AU2001226023A1 (en) | 2000-02-18 | 2001-08-27 | Luigi Grasso | A method for generating hypermutable plants |
| WO2001062945A1 (en) | 2000-02-23 | 2001-08-30 | The Johns Hopkins University | Methods for generating hypermutable yeast |
| US6825038B2 (en) | 2000-05-12 | 2004-11-30 | The Johns Hopkins University | Method for generating hypermutable organisms |
| AU2000258017A1 (en) * | 2000-07-17 | 2002-02-13 | Jiahui Xia | Human source gene leading sequence, gene vector and gene expression strategy |
| US6844152B1 (en) | 2000-09-15 | 2005-01-18 | Promega Corporation | Detection of microsatellite instability and its use in diagnosis of tumors |
| US20020058265A1 (en) * | 2000-09-15 | 2002-05-16 | Promega Corporation | Detection of microsatellite instability and its use in diagnosis of tumors |
| US6737268B1 (en) | 2000-11-14 | 2004-05-18 | Morphotek, Inc. | Method for generating genetically altered antigens |
| JP2005509399A (ja) * | 2000-11-14 | 2005-04-14 | モーフオテク・インコーポレーテツド | 遺伝的に改変された抗原の生成法 |
| US7070940B2 (en) * | 2002-07-18 | 2006-07-04 | Aventis Pharma S.A. | Method for determining the ability of a compound to modify the interaction between parkin and the p38 protein |
| KR100575251B1 (ko) * | 2003-03-03 | 2006-05-02 | 재단법인서울대학교산학협력재단 | p38/JTV-1을 유효성분으로 하는 암 치료용 약학적조성물 및 암 치료용 약학적 조성물의 스크리닝 방법 |
| JP5675109B2 (ja) | 2007-02-20 | 2015-02-25 | アナプティスバイオ インコーポレイティッド | ライブラリーの生成方法及びその使用 |
| EP2566499B1 (de) * | 2010-05-04 | 2017-01-25 | aTyr Pharma, Inc. | Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten aus einem p38-multi-trna-synthetase-komplex |
-
1995
- 1995-08-24 US US08/518,862 patent/US5843757A/en not_active Expired - Lifetime
-
1996
- 1996-08-26 WO PCT/US1996/013598 patent/WO1997008312A1/en not_active Ceased
- 1996-08-26 JP JP9510440A patent/JPH11511323A/ja active Pending
- 1996-08-26 CA CA002229789A patent/CA2229789A1/en not_active Abandoned
- 1996-08-26 DE DE69630458T patent/DE69630458D1/de not_active Expired - Lifetime
- 1996-08-26 EP EP96930577A patent/EP0852620B1/de not_active Expired - Lifetime
- 1996-08-26 AT AT96930577T patent/ATE252638T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69630458D1 (de) | 2003-11-27 |
| US5843757A (en) | 1998-12-01 |
| EP0852620A1 (de) | 1998-07-15 |
| EP0852620B1 (de) | 2003-10-22 |
| CA2229789A1 (en) | 1997-03-06 |
| JPH11511323A (ja) | 1999-10-05 |
| WO1997008312A1 (en) | 1997-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |