ATE252891T1 - Kationische lipid-nukleinsäure komplexe - Google Patents

Kationische lipid-nukleinsäure komplexe

Info

Publication number
ATE252891T1
ATE252891T1 AT97934685T AT97934685T ATE252891T1 AT E252891 T1 ATE252891 T1 AT E252891T1 AT 97934685 T AT97934685 T AT 97934685T AT 97934685 T AT97934685 T AT 97934685T AT E252891 T1 ATE252891 T1 AT E252891T1
Authority
AT
Austria
Prior art keywords
acid complexes
cationic lipid
lipid
suspension
nuclic acid
Prior art date
Application number
AT97934685T
Other languages
English (en)
Inventor
Rainer Bischoff
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Application granted granted Critical
Publication of ATE252891T1 publication Critical patent/ATE252891T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97934685T 1996-08-26 1997-08-25 Kationische lipid-nukleinsäure komplexe ATE252891T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96401819 1996-08-26
PCT/IB1997/001030 WO1998008489A1 (en) 1996-08-26 1997-08-25 Cationic lipid-nucleic acid complexes

Publications (1)

Publication Number Publication Date
ATE252891T1 true ATE252891T1 (de) 2003-11-15

Family

ID=8225285

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97934685T ATE252891T1 (de) 1996-08-26 1997-08-25 Kationische lipid-nukleinsäure komplexe

Country Status (11)

Country Link
US (1) US6271208B1 (de)
EP (1) EP0941066B1 (de)
JP (1) JP2000516948A (de)
AT (1) ATE252891T1 (de)
AU (1) AU729077B2 (de)
CA (1) CA2264140A1 (de)
DE (1) DE69725877T2 (de)
DK (1) DK0941066T3 (de)
ES (1) ES2208936T3 (de)
PT (1) PT941066E (de)
WO (1) WO1998008489A1 (de)

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US8334364B2 (en) 2006-11-06 2012-12-18 Nipon Kayaku Kabushiki Kaisha High-molecular weight derivative of nucleic acid antimetabolite
JP5548365B2 (ja) 2006-11-08 2014-07-16 日本化薬株式会社 核酸系代謝拮抗剤の高分子誘導体
US8357531B2 (en) 2007-07-03 2013-01-22 Transgene S.A. Immortalized avian cell lines
SI2170279T1 (en) 2007-07-31 2018-04-30 Otsuka Pharmaceutical Co., Ltd. Methods for producing aripiprazole suspension and freeze-dried formulation
JP5349318B2 (ja) 2007-09-28 2013-11-20 日本化薬株式会社 ステロイド類の高分子結合体
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JP5366940B2 (ja) 2008-05-08 2013-12-11 日本化薬株式会社 葉酸若しくは葉酸誘導体の高分子結合体
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JP6586075B2 (ja) 2013-03-14 2019-10-02 トランスレイト バイオ， インコーポレイテッド メッセンジャーｒｎａの精製方法
JP6620093B2 (ja) * 2013-07-23 2019-12-11 アービュートゥス バイオファーマ コーポレイションＡｒｂｕｔｕｓ Ｂｉｏｐｈａｒｍａ Ｃｏｒｐｏｒａｔｉｏｎ メッセンジャーｒｎａを送達するための組成物及び方法
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Also Published As

Publication number Publication date
EP0941066A1 (de) 1999-09-15
DE69725877T2 (de) 2004-07-22
AU729077B2 (en) 2001-01-25
US6271208B1 (en) 2001-08-07
DE69725877D1 (de) 2003-12-04
WO1998008489A1 (en) 1998-03-05
ES2208936T3 (es) 2004-06-16
AU3781597A (en) 1998-03-19
DK0941066T3 (da) 2004-02-23
JP2000516948A (ja) 2000-12-19
PT941066E (pt) 2004-03-31
EP0941066B1 (de) 2003-10-29
CA2264140A1 (en) 1998-03-05

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