ATE253381T1 - Verfahren zur detektion und lokalisation maligner meschlicher tumore des pankreas - Google Patents

Verfahren zur detektion und lokalisation maligner meschlicher tumore des pankreas

Info

Publication number
ATE253381T1
ATE253381T1 AT98904839T AT98904839T ATE253381T1 AT E253381 T1 ATE253381 T1 AT E253381T1 AT 98904839 T AT98904839 T AT 98904839T AT 98904839 T AT98904839 T AT 98904839T AT E253381 T1 ATE253381 T1 AT E253381T1
Authority
AT
Austria
Prior art keywords
pancreas
detecting
composition
relates
neurotensin
Prior art date
Application number
AT98904839T
Other languages
English (en)
Inventor
J C Reubi
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE253381T1 publication Critical patent/ATE253381T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/085—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being neurotensin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Nuclear Medicine (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
AT98904839T 1997-02-03 1998-02-02 Verfahren zur detektion und lokalisation maligner meschlicher tumore des pankreas ATE253381T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200297 1997-02-03
PCT/US1998/001964 WO1998033531A1 (en) 1997-02-03 1998-02-02 Method for the detection and localization of malignant human tumours

Publications (1)

Publication Number Publication Date
ATE253381T1 true ATE253381T1 (de) 2003-11-15

Family

ID=26146106

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98904839T ATE253381T1 (de) 1997-02-03 1998-02-02 Verfahren zur detektion und lokalisation maligner meschlicher tumore des pankreas

Country Status (11)

Country Link
US (2) US6312661B1 (de)
EP (1) EP0968001B1 (de)
JP (1) JP2001511152A (de)
AT (1) ATE253381T1 (de)
AU (1) AU728712C (de)
CA (1) CA2279530C (de)
DE (1) DE69819478T2 (de)
HU (1) HUP0001316A3 (de)
IL (1) IL131386A0 (de)
NO (1) NO993846L (de)
WO (1) WO1998033531A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3340699B2 (ja) * 1998-06-05 2002-11-05 東京瓦斯株式会社 膵外分泌機能診断剤
US7232559B1 (en) 1999-06-04 2007-06-19 Tokyo Gas Company Limited Diagnostic agents for pancreatic exocrine function
AU2119101A (en) * 1999-10-22 2001-05-08 Insight Neuroimaging Systems, Llc Ligand chelated paramagnetic mri contrast agents
US8175890B2 (en) * 2001-10-30 2012-05-08 Biodose, Llc Pharmacy based method and algorithm for handling of radioactive pharmaceuticals and generating of reports therefrom
US7630907B2 (en) * 2001-10-30 2009-12-08 Biodose, Llc Algorithm and program for the handling and administration of radioactive pharmaceuticals
US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
WO2004065621A1 (en) 2002-03-01 2004-08-05 Dyax Corp. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US20040039241A1 (en) * 2002-05-29 2004-02-26 Biodose Llc Integrated distribution and communication process and algorithm for providing, handling, distributing or generating reports regarding radioactive pharmaceuticals
AU2003259172A1 (en) * 2002-07-24 2004-02-09 The Salk Institute For Biological Studies Receptor (sstr4)- selective somatostatin analogs
GR1004637B (el) * 2003-04-04 2004-07-23 Βιομεντικααλαιφασαιενσισαανωνυμηαεταιριααφαρμακευτικωναπροιοντωναα Συνθεσηαβιολογικηακαιαπροκλινικηααξιολογησηααναλογωνανευροτενσινησα}@@bατροποποιημενωναμεαπαραγωγαατουᐏ@ϊ@τετρααζαενδεκανιουα}@ϊ@tetraazaundecanebακαιαεπισημασμενωναμεατεχνητιο@mα}αηαλλααραδιονουκλιδιαατουατεχνητιουbαη@καιαρηνιο@ϊϊα}΄ηααλλααραδιονουκλιδιαατουαρηνιουbαγιααεφαρμογηαστηναογκολογιαα
BRPI0414512B8 (pt) * 2003-09-17 2021-05-25 Board Of Regentes The Univ Of Texas System composição para reproduzir imagens de um pâncreas e uso desta
US7507547B2 (en) * 2004-09-09 2009-03-24 University Of Massachusetts Screening assays for antioxidants and antiproliferative compounds
US20060062729A1 (en) * 2004-09-09 2006-03-23 Carraway Robert E Enhanced ligand binding to neurotensin receptors
ES2538002T3 (es) 2009-01-07 2015-06-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Métodos para el tratamiento, la evaluación pronóstica y la detección de cáncer de mama
US9809624B2 (en) * 2009-07-16 2017-11-07 Inserm (Institut National De La Sante Et De La Recherche Medicale) Neurotensin analogues for radioisotope targeting to neurotensin receptor-positive tumors
US8378134B2 (en) 2009-09-30 2013-02-19 General Electric Company Hydroxylated contrast enhancement agents
EP2740726A1 (de) 2012-12-07 2014-06-11 3B Pharmaceuticals GmbH Neurotensin-Rezeptorligande
CA2949936C (en) 2014-06-10 2022-10-18 3B Pharmaceuticals Gmbh Conjugate comprising a neurotensin receptor ligand and use thereof
EP2954933A1 (de) 2014-06-10 2015-12-16 3B Pharmaceuticals GmbH Konjugat mit einem Neurotensinrezptorligand
EP2954934A1 (de) 2014-06-11 2015-12-16 3B Pharmaceuticals GmbH Konjugat aus einem Neurotensinrezeptorliganden und Verwendung davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687680A1 (fr) * 1992-02-20 1993-08-27 Centre Nat Rech Scient Procede de marquage de proteines et de peptides par acylation de leur fonction alpha aminee par un reactif comportant une fonction carboxylique activee.
JPH07505621A (ja) * 1992-03-25 1995-06-22 マリンクロッド・インコーポレイテッド 外科手術中における腫瘍組織の検出および探知法
CA2086453A1 (en) * 1992-12-30 1994-07-01 Mcgill University Marker for neurotensin receptor
DE4337599A1 (de) * 1993-11-01 1995-05-04 Diagnostikforschung Inst Metallbindende cysteinfreie Peptide für Diagnose und Therapie, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
EP0752873A4 (de) * 1994-02-18 2002-05-15 Mallinckrodt Inc Markierte peptidverbindungen
FR2720066B1 (fr) * 1994-05-20 1996-06-28 Rhone Poulenc Rorer Sa Peptides antagonistes de la neurotensine.
FR2722193B1 (fr) * 1994-07-08 1996-10-04 Sanofi Sa Derives n-oxydes de 1-(7-chloro-4-quinoleinyl)pyrazole-3-carboxamides substitues, procede pour leur preparation et les compositions pharmaceitiques les contenant
WO1996023527A1 (en) * 1995-02-03 1996-08-08 Mallinckrodt Medical, Inc. Method for the detection and localization of malignant human tumours

Also Published As

Publication number Publication date
HUP0001316A3 (en) 2001-10-29
NO993846D0 (no) 1999-08-10
HUP0001316A2 (hu) 2000-09-28
EP0968001B1 (de) 2003-11-05
US6312661B1 (en) 2001-11-06
US20020155064A1 (en) 2002-10-24
AU6262298A (en) 1998-08-25
AU728712B2 (en) 2001-01-18
EP0968001A1 (de) 2000-01-05
IL131386A0 (en) 2001-01-28
DE69819478T2 (de) 2004-09-02
WO1998033531A1 (en) 1998-08-06
CA2279530A1 (en) 1998-08-06
CA2279530C (en) 2009-04-28
DE69819478D1 (de) 2003-12-11
JP2001511152A (ja) 2001-08-07
NO993846L (no) 1999-09-09
AU728712C (en) 2001-07-19

Similar Documents

Publication Publication Date Title
DE69819478D1 (de) Verfahren zur detektion und lokalisation maligner meschlicher tumore des pankreas
Tjuvajev et al. Iododeoxyuridine uptake and retention as a measure of tumor growth
Ruserb et al. Somatostatin analogues for somatostatin-receptor-mediated radiotherapy of cancer
EP2940474B1 (de) Neuartige markierungszusammensetzung für krebsläsionen
KR102396324B1 (ko) 인 시츄 면역 조절 암 백신화를 위한 표적화된 방사선요법 킬레이트
US20250186632A1 (en) Fibroblast activation protein targeting peptides
Liu et al. 99mTc-labeled SWL specific peptide for targeting EphA2 receptor
O'Byrne et al. Scintigraphic imaging of small-cell lung cancer with [111In] pentetreotide, a radiolabelled somatostatin analogue
N Eberle et al. Synthetic peptide drugs for targeting skin cancer: malignant melanoma and melanotic lesions
JP2022549258A (ja) セラノスティックスとして使用するための放射性標識grprアンタゴニスト
Wu et al. Development of the research on the application of chlorotoxin in imaging diagnostics and targeted therapies for tumors
KR20170104398A (ko) Glypican-3에 선택적으로 결합하는 압타머 및 이의 용도
US20060188441A1 (en) Radiolabeled gallium complexes, methods for synthesis and use for PET imaging of EGFR expression in malignant tumors
Guo et al. A novel indium-111-labeled gonadotropin-releasing hormone peptide for human prostate cancer imaging
Nock et al. Theranostic perspectives in prostate cancer with the GRPR-antagonist NeoBOMB1–preclinical and first clinical results
JP2005514335A (ja) 腫瘍イメージング及び治療のためのpacap組成物及び方法
US11213597B2 (en) Kinin-based theranostic probes for solid cancers and uses thereof
JP2002516882A5 (de)
US20170326166A1 (en) Compositions and methods for treating pituitary tumors
WO1997031657A3 (en) Use of labelled cck-b receptor ligands for the detection and localization of malignant human tumors
Keenan Immunolymphoscintigraphy
Kinuya et al. Short-period-induced hypertension could improve tumor-to-nontumor ratios of radiolabeled monoclonal antibody
Tjuvajev et al. Measure of Tumor Growth
Ertl Inhibitory Effect of Bombesin Receptor Antagonist RC3095 on the Growth of Human Pancreatic Cancer Cells in Vivo and in Vitro
WO1999049900A1 (en) Tumour imaging and therapeutic agents

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties